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Select item 112113151.

Single-cell transcriptomic profiling reveals decreased ER protein Reticulon3 drives the progression of renal fibrosis

Shuai Guo, Yi Dong, Ran Du, Yu-Xing Liu, Shu Liu, Qin Wang, Ji-Shi Liu, Hui Xu, Yu-Jie Jiang, Huang Hao, Liang-Liang Fan, Rong Xiang

Mol Biomed. 2024 Dec; 5: 24. Published online 2024 Jun 28. doi: 10.1186/s43556-024-00187-x

PMCID:: PMC11211315

Abstract Article PDF–24M

Select item 109238872.

Lipid overload-induced RTN3 activation leads to cardiac dysfunction by promoting lipid droplet biogenesis

Dong Guo, Mingming Zhang, Bingchao Qi, Tingwei Peng, Mingchuan Liu, Zhelong Li, Feng Fu, Yanjie Guo, Congye Li, Ying Wang, Lang Hu, Yan Li

Cell Death Differ. 2024 Mar; 31(3): 292–308. Published online 2023 Nov 28. doi: 10.1038/s41418-023-01241-x

PMCID:: PMC10923887

Abstract Article PDF–7.7M

Select item 48874203.

Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer’s disease

Md. Golam Sharoar, Qi Shi, Yingying Ge, Wanxia He, Xiangyou Hu, George Perry, Xiongwei Zhu, Riqiang Yan

Mol Psychiatry. Author manuscript; available in PMC 2016 Aug 23.

Published in final edited form as: Mol Psychiatry. 2016 Sep; 21(9): 1263–1271. Published online 2015 Dec 1. doi: 10.1038/mp.2015.181

PMCID:: PMC4887420

Abstract Article PDF–1.5M

Select item 18886694.

Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities

Xiangyou Hu, Qi Shi, Xiangdong Zhou, Wanxia He, Hong Yi, Xinghua Yin, Marla Gearing, Allan Levey, Riqiang Yan

EMBO J. 2007 Jun 6; 26(11): 2755–2767. Published online 2007 May 3. doi: 10.1038/sj.emboj.7601707

PMCID:: PMC1888669

Abstract Article PDF–589K

Select item 53446855.

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3

Amandine Bastide, Diego Peretti, John R.P. Knight, Stefano Grosso, Ruth V. Spriggs, Xavier Pichon, Thomas Sbarrato, Anne Roobol, Jo Roobol, Davide Vito, Martin Bushell, Tobias von der Haar, C. Mark Smales, Giovanna R. Mallucci, Anne E. Willis

Curr Biol. 2017 Mar 6; 27(5): 638–650. doi: 10.1016/j.cub.2017.01.047

PMCID:: PMC5344685

Abstract Article

Select item 29303756.

Expression of reticulon 3 in Alzheimer’s disease brain

Hideaki Kume, Yoshihiro Konishi, Kiyoko S. Murayama, Fuyuki Kametani, Wataru Araki

Neuropathol Appl Neurobiol. Author manuscript; available in PMC 2010 Aug 31.

Published in final edited form as: Neuropathol Appl Neurobiol. 2009 Apr; 35(2): 178–188. doi: 10.1111/j.1365-2990.2008.00974.x

PMCID:: PMC2930375

Abstract Article PDF–1.2M

Select item 11346807.

Tissue specificity and regulation of the N-terminal diversity of reticulon 3

Franck Di Scala, Luc Dupuis, Christian Gaiddon, Marc De Tapia, Natasa Jokic, Jose-Luis Gonzalez De Aguilar, Jean-Sébastien Raul, Bertrand Ludes, Jean-Philippe Loeffler

Biochem J. 2005 Jan 1; 385(Pt 1): 125–134. Prepublished online 2004 Sep 7. Published online 2004 Dec 14. doi: 10.1042/BJ20040458

PMCID:: PMC1134680

Abstract Article PDF–1.1M

Select item 41985398.

Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition

Qi Shi, Yingying Ge, Md. Golam Sharoar, Wanxia He, Rong Xiang, Zhuohua Zhang, Xiangyou Hu, Riqiang Yan

J Neurosci. 2014 Oct 15; 34(42): 13954–13962. doi: 10.1523/JNEUROSCI.1588-14.2014

PMCID:: PMC4198539

Abstract Article PDF–3.1M

Select item 37984909.

Increased Expression of Reticulon 3 in Neurons Leads to Reduced Axonal Transport of β Site Amyloid Precursor Protein-cleaving Enzyme 1

Minzi Deng, Wanxia He, Ya Tan, Hailong Han, Xiangyou Hu, Kun Xia, Zhuohua Zhang, Riqiang Yan

J Biol Chem. 2013 Oct 18; 288(42): 30236–30245. Published online 2013 Sep 4. doi: 10.1074/jbc.M113.480079

PMCID:: PMC3798490

Abstract Article PDF–2.3M

Select item 916679110.

Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells

Liang-Liang Fan, Ran Du, Ji-Shi Liu, Jie-Yuan Jin, Chen-Yu Wang, Yi Dong, Wan-Xia He, Ri-Qiang Yan, Rong Xiang

Exp Mol Med. 2022 May; 54(5): 653–661. Published online 2022 May 20. doi: 10.1038/s12276-022-00763-7

PMCID:: PMC9166791

Abstract Article PDF–4.6M

Select item 851446011.

PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones

Yu-Jie Chen, Jeffrey Knupp, Anoop Arunagiri, Leena Haataja, Peter Arvan, Billy Tsai

Nat Commun. 2021; 12: 5991. Published online 2021 Oct 13. doi: 10.1038/s41467-021-26225-8

PMCID:: PMC8514460

Abstract Article PDF–6.4M

Select item 831580512.

RTN3 inhibits RIG-I-mediated antiviral responses by impairing TRIM25-mediated K63-linked polyubiquitination

Ziwei Yang, Jun Wang, Bailin He, Xiaolin Zhang, Xiaojuan Li, Ersheng Kuang

eLife. 2021; 10: e68958. Published online 2021 Jul 27. doi: 10.7554/eLife.68958

Correction in:: eLife. 2021; 10: e73737.

PMCID:: PMC8315805

Abstract Article PDF–5.9M

Select item 552244813.

RTN1 and RTN3 protein are differentially associated with senile plaques in Alzheimer’s brains

Qi Shi, Yingying Ge, Wanxia He, Xiangyou Hu, Riqiang Yan

Sci Rep. 2017; 7: 6145. Published online 2017 Jul 21. doi: 10.1038/s41598-017-05504-9

PMCID:: PMC5522448

Abstract Article PDF–1.8M

Select item 639246614.

Increased RTN3 leads to obesity and hypertriglyceridemia by interacting with HSPA5

Rong Xiang, Liang-liang Fan, Hao Huang, Ya-qin Chen, Wanxia He, Shuai Guo, Jing-Jing Li, Jie-yuan Jin, Ran Du, Riqiang Yan, Kun Xia

Circulation. Author manuscript; available in PMC 2019 Oct 23.

Published in final edited form as: Circulation. 2018 Oct 23; 138(17): 1828–1838. doi: 10.1161/CIRCULATIONAHA.117.030718

PMCID:: PMC6392466

Abstract Article PDF–858K

Select item 1040771015.

Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development

John Zhou, Qi Shi, Ying Y Ge, Wanxia He, Xiangyou Hu, Weiming Xia, Riqiang Yan

Hum Mol Genet. 2023 Aug 15; 32(16): 2587–2599. Published online 2023 May 25. doi: 10.1093/hmg/ddad085

PMCID:: PMC10407710

Abstract Article PDF–2.5M

Select item 274635916.

A class of dynamin-like GTPases involved in the generation of the tubular ER network

Junjie Hu, Yoko Shibata, Peng-Peng Zhu, Christiane Voss, Neggy Rismanchi, William A. Prinz, Tom A. Rapoport, Craig Blackstone

Cell. Author manuscript; available in PMC 2010 Feb 7.

Published in final edited form as: Cell. 2009 Aug 7; 138(3): 549–561. doi: 10.1016/j.cell.2009.05.025

PMCID:: PMC2746359

Abstract Article PDF–2.4M

Select item 809881417.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 268625218.

The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

Stephen N. Sansom, Dean S. Griffiths, Andrea Faedo, Dirk-Jan Kleinjan, Youlin Ruan, James Smith, Veronica van Heyningen, John L. Rubenstein, Frederick J. Livesey

PLoS Genet. 2009 Jun; 5(6): e1000511. Published online 2009 Jun 12. doi: 10.1371/journal.pgen.1000511