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Select item 93464691.

Hypoxia‐induced ELF3 promotes tumor angiogenesis through IGF1/IGF1R

Seung Hee Seo, Soo‐Yeon Hwang, Seohui Hwang, Sunjung Han, Hyojin Park, Yun‐Sil Lee, Seung Bae Rho, Youngjoo Kwon

EMBO Rep. 2022 Aug; 23(8): e52977. Published online 2022 Jun 13. doi: 10.15252/embr.202152977

PMCID:: PMC9346469

Abstract Article PDF–2.9M

Select item 92493412.

ETS transcription factor ELF3 (ESE‐1) is a cell cycle regulator in benign and malignant prostate

Leanne K. Archer, Fiona M. Frame, Hannah F. Walker, Alastair P. Droop, Georgina L. K. McDonald, Samuel Kucko, Daniel M. Berney, Vincent M. Mann, Matthew S. Simms, Norman J. Maitland

FEBS Open Bio. 2022 Jul; 12(7): 1365–1387. Published online 2022 May 6. doi: 10.1002/2211-5463.13417

PMCID:: PMC9249341

Abstract Article PDF–4.8M

Select item 89631313.

ELF3 mediates IL-1α induced differentiation of mesenchymal stem cells to inflammatory iCAFs

Linda L. Tran, Truong Dang, Rintu Thomas, David R. Rowley

Stem Cells. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Stem Cells. 2021 Dec; 39(12): 1766–1777. Published online 2021 Oct 7. doi: 10.1002/stem.3455

PMCID:: PMC8963131

Abstract Article PDF–1.1M

Select item 82277324.

Nanopore Sequencing Unveils Diverse Transcript Variants of the Epithelial Cell-Specific Transcription Factor Elf-3 in Human Malignancies

Michaela A. Boti, Panagiotis G. Adamopoulos, Panagiotis Tsiakanikas, Andreas Scorilas

Genes (Basel) 2021 Jun; 12(6): 839. Published online 2021 May 29. doi: 10.3390/genes12060839

PMCID:: PMC8227732

Abstract Article PDF–1.4M

Select item 78807225.

ELF3 Overexpression as Prognostic Biomarker for Recurrence of Stage II Colorectal Cancer

AYUMI TAKAOKA, TOSHIAKI ISHIKAWA, SATOSHI OKAZAKI, SHUICHI WATANABE, FUYUKI MIYA, TATSUHIKO TSUNODA, AKIFUMI KIKUCHI, SHINICHI YAMAUCHI, TAKATOSHI MATSUYAMA, MASANORI TOKUNAGA, HIROYUKI UETAKE, YUSUKE KINUGASA

In Vivo. 2021 Jan-Feb; 35(1): 191–201. Published online 2021 Jan 3. doi: 10.21873/invivo.12248

PMCID:: PMC7880722

Abstract Article PDF–2.5M

Select item 74452886.

Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate

Akhilesh Pandey, Eric W. Stawiski, Steffen Durinck, Harsha Gowda, Leonard D. Goldstein, Mustafa A. Barbhuiya, Markus S. Schröder, Sreelakshmi K. Sreenivasamurthy, Sun-Whe Kim, Sameer Phalke, Kushal Suryamohan, Kayla Lee, Papia Chakraborty, Vasumathi Kode, Xiaoshan Shi, Aditi Chatterjee, Keshava Datta, Aafaque A. Khan, Tejaswini Subbannayya, Jing Wang, Subhra Chaudhuri, Sanjiv Gupta, Braj Raj Shrivastav, Bijay S. Jaiswal, Satish S. Poojary, Shushruta Bhunia, Patricia Garcia, Carolina Bizama, Lorena Rosa, Wooil Kwon, Hongbeom Kim, Youngmin Han, Thakur Deen Yadav, Vedam L. Ramprasad, Amitabha Chaudhuri, Zora Modrusan, Juan Carlos Roa, Pramod Kumar Tiwari, Jin-Young Jang, Somasekar Seshagiri

Nat Commun. 2020; 11: 4225. Published online 2020 Aug 24. doi: 10.1038/s41467-020-17880-4

PMCID:: PMC7445288

Abstract Article PDF–16M

Select item 67216827.

The Transcription Factor Elf3 Is Essential for a Successful Mesenchymal to Epithelial Transition

Burcu Sengez, Ilkin Aygün, Huma Shehwana, Neslihan Toyran, Sanem Tercan Avci, Ozlen Konu, Marc P. Stemmler, Hani Alotaibi

Cells. 2019 Aug; 8(8): 858. Published online 2019 Aug 9. doi: 10.3390/cells8080858

PMCID:: PMC6721682

Abstract Article PDF–2.3M

Select item 53700138.

ELF3 is a negative regulator of epithelial-mesenchymal transition in ovarian cancer cells

Tsz-Lun Yeung, Cecilia S. Leung, Kwong-Kwok Wong, Arthur Gutierrez-Hartmann, Joseph Kwong, David M. Gershenson, Samuel C. Mok

Oncotarget. 2017 Mar 7; 8(10): 16951–16963. Published online 2017 Feb 9. doi: 10.18632/oncotarget.15208

PMCID:: PMC5370013

Abstract Article PDF–9.3M

Select item 49823769.

Ampullary cancers harbor ELF3 tumor suppressor gene mutations and exhibit frequent WNT dysregulation

Marie-Claude Gingras, Kyle R. Covington, David K. Chang, Lawrence A. Donehower, Anthony J. Gill, Michael M. Ittmann, Chad J. Creighton, Amber L. Johns, Eve Shinbrot, Ninad Dewal, William E. Fisher, Australian Pancreatic Cancer Genome Initiative, Christian Pilarsky, Robert Grützmann, Michael J. Overman, Nigel B. Jamieson, George Van Buren, II, Jennifer Drummond, Kimberly Walker, Oliver A. Hampton, Liu Xi, Donna M. Muzny, Harsha Doddapaneni, Sandra L. Lee, Michelle Bellair, Jianhong Hu, Yi Han, Huyen H. Dinh, Mike Dahdouli, Jaswinder S. Samra, Peter Bailey, Nicola Waddell, John V. Pearson, Ivon Harliwong, Huamin Wang, Daniela Aust, Karin A. Oien, Ralph H. Hruban, Sally E. Hodges, Amy McElhany, Charupong Saengboonmee, Fraser R. Duthie, Sean M. Grimmond, Andrew V. Biankin, David A. Wheeler, Richard A. Gibbs

Cell Rep. Author manuscript; available in PMC 2016 Aug 12.

Published in final edited form as: Cell Rep. 2016 Feb 2; 14(4): 907–919. Published online 2016 Jan 21. doi: 10.1016/j.celrep.2015.12.005

PMCID:: PMC4982376

Abstract Article PDF–2.7M

Select item 404787110.

Elf3 drives β-catenin transactivation and associates with poor prognosis in colorectal cancer

J-L Wang, Z-F Chen, H-M Chen, M-Y Wang, X Kong, Y-C Wang, T-T Sun, J Hong, W Zou, J Xu, J-Y Fang

Cell Death Dis. 2014 May; 5(5): e1263. Published online 2014 May 29. doi: 10.1038/cddis.2014.206

PMCID:: PMC4047871

Abstract Article PDF–5.3M

Select item 318303011.

Mapping of ESE-1 subdomains required to initiate mammary epithelial cell transformation via a cytoplasmic mechanism

Jason D Prescott, Joanna M Poczobutt, John J Tentler, Darius M Walker, Arthur Gutierrez-Hartmann

Mol Cancer. 2011; 10: 103. Published online 2011 Aug 28. doi: 10.1186/1476-4598-10-103

PMCID:: PMC3183030

Abstract Article PDF–2.1M

Select item 41989112.

The ETS Transcription Factor ESE-1 Transforms MCF-12A Human Mammary Epithelial Cells via a Novel Cytoplasmic Mechanism

Jason D. Prescott, Karen S. N. Koto, Meenakshi Singh, Arthur Gutierrez-Hartmann

Mol Cell Biol. 2004 Jun; 24(12): 5548–5564. doi: 10.1128/MCB.24.12.5548-5564.2004

PMCID:: PMC419891

Abstract Article PDF–1.0M

Select item 14704513.

The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis.

J M Andreoli, S I Jang, E Chung, C M Coticchia, P M Steinert, N G Markova

Nucleic Acids Res. 1997 Nov 1; 25(21): 4287–4295. doi: 10.1093/nar/25.21.4287

PMCID:: PMC147045

Summary PDF–553K

Select item 1023661714.

An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma

Masafumi Horie, Hidenori Tanaka, Masami Suzuki, Yoshihiko Sato, So Takata, Erina Takai, Naoya Miyashita, Akira Saito, Yoichiro Nakatani, Shinichi Yachida

Cancer Sci. 2023 Jun; 114(6): 2596–2608. Published online 2023 Mar 15. doi: 10.1111/cas.15764

PMCID:: PMC10236617

Abstract Article PDF–3.5M

Select item 1002815315.

ESE1/AGR2 axis antagonizes TGF‐β‐induced epithelial‐mesenchymal transition in low‐grade pancreatic cancer

Hui‐Jing Xu, Jing Bai, Ye Tian, Xiao Feng, Ai‐Ping Chen, Jie Wang, Jin Wu, Xu‐Ru Jin, Feng Zhang, Mei‐Yu Quan, Chengshui Chen, Kwang‐youl Lee, Jin‐San Zhang

Cancer Med. 2023 Mar; 12(5): 5979–5993. Published online 2022 Nov 3. doi: 10.1002/cam4.5397

PMCID:: PMC10028153

Abstract Article PDF–9.5M

Select item 981018916.

MYB and ELF3 differentially modulate labor-inducing gene expression in myometrial cells

Virlana M. Shchuka, Nawrah Khader, Anna Dorogin, Oksana Shynlova, Jennifer A. Mitchell

PLoS One. 2023; 18(1): e0271081. Published online 2023 Jan 3. doi: 10.1371/journal.pone.0271081

PMCID:: PMC9810189

Abstract Article PDF–1.4M

Select item 851905617.

Vorinostat ameliorates IL‐1α‐induced reduction of type II collagen by inhibiting the expression of ELF3 in chondrocytes

Xudong Miao, Yongping Wu, Ping Wang, Qiang Zhang, Chenhe Zhou, Xinning Yu, Le Cao

J Biochem Mol Toxicol. 2021 Sep; 35(9): e22844. Published online 2021 Jul 11. doi: 10.1002/jbt.22844

PMCID:: PMC8519056

Abstract Article PDF–2.7M

Select item 802650618.

A transcriptional regulatory loop of master regulator transcription factors, PPARG, and fatty acid synthesis promotes esophageal adenocarcinoma

Sai Ma, Bo Zhou, Qian Yang, Yunzhi Pan, Wei Yang, Stephen J. Freedland, Ling-Wen Ding, Michael R. Freeman, Joshua J. Breunig, Neil A. Bhowmick, Jian Pan, H. Phillip Koeffler, De-Chen Lin

Cancer Res. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Cancer Res. 2021 Mar 1; 81(5): 1216–1229. Published online 2021 Jan 5. doi: 10.1158/0008-5472.CAN-20-0652

PMCID:: PMC8026506

Abstract Article PDF–1.4M

Select item 793634919.

ELF3 activated by a superenhancer and an autoregulatory feedback loop is required for high-level HLA-C expression on extravillous trophoblasts

Qin Li, Torsten B. Meissner, Fang Wang, Ziming Du, Sai Ma, Sarika Kshirsagar, Tamara Tilburgs, Jason D. Buenrostro, Motonari Uesugi, Jack L. Strominger

Proc Natl Acad Sci U S A. 2021 Mar 2; 118(9): e2025512118. Published online 2021 Feb 23. doi: 10.1073/pnas.2025512118

PMCID:: PMC7936349

Abstract Article PDF–1.2M

Select item 789874520.

FZD5 prevents epithelial-mesenchymal transition in gastric cancer

Dan Dong, Lei Na, Kailing Zhou, Zhuo Wang, Yu Sun, Qianqian Zheng, Jian Gao, Chenghai Zhao, Wei Wang

Cell Commun Signal. 2021; 19: 21. Published online 2021 Feb 22. doi: 10.1186/s12964-021-00708-z

PMCID:: PMC7898745

Abstract Article PDF–7.2M

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