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Select item 88095071.

RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4⁺ T-cell-dependent antitumor immunity

Zhuo Zhang, Lin Luo, Chuan Xing, Yu Chen, Peng Xu, Mao Li, Ling Zeng, Chao Li, Sadashib Ghosh, Deborah Della Manna, Tim Townes, William J. Britt, Narendra Wajapeyee, Barry P. Sleckman, Zechen Chong, Jianmei Wu Leavenworth, Eddy S Yang

Nat Cancer. Author manuscript; available in PMC 2022 Apr 22.

Published in final edited form as: Nat Cancer. 2021 Oct; 2(10): 1018–1038. Published online 2021 Oct 22. doi: 10.1038/s43018-021-00263-z

PMCID:: PMC8809507

Abstract Article PDF–7.2M

Select item 64144252.

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes

Konstantina Skourti-Stathaki, Elena Torlai Triglia, Marie Warburton, Philipp Voigt, Adrian Bird, Ana Pombo

Mol Cell. 2019 Mar 7; 73(5): 930–945.e4. doi: 10.1016/j.molcel.2018.12.016

PMCID:: PMC6414425

Abstract Article PDF–6.4M

Select item 45793473.

The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development

Robert S. Illingworth, Michael Moffat, Abigail R. Mann, David Read, Chris J. Hunter, Madapura M. Pradeepa, Ian R. Adams, Wendy A. Bickmore

Genes Dev. 2015 Sep 15; 29(18): 1897–1902. doi: 10.1101/gad.268151.115

PMCID:: PMC4579347

Abstract Article PDF–843K

Select item 28170094.

Eukaryotic DING Proteins Are Endogenous: An Immunohistological Study in Mouse Tissues

Jean-Marc Collombet, Mikael Elias, Guillaume Gotthard, Elise Four, Frédérique Renault, Aurélie Joffre, Dominique Baubichon, Daniel Rochu, Eric Chabrière

PLoS One. 2010; 5(2): e9099. Published online 2010 Feb 8. doi: 10.1371/journal.pone.0009099

PMCID:: PMC2817009

Abstract Article PDF–1.7M

Select item 20644425.

Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells

Martin Leeb, Anton Wutz

J Cell Biol. 2007 Jul 16; 178(2): 219–229. doi: 10.1083/jcb.200612127

PMCID:: PMC2064442

Abstract Article PDF–1.4M

Select item 56479396.

Polycomb directs timely activation of germline genes in spermatogenesis

So Maezawa, Kazuteru Hasegawa, Masashi Yukawa, Akihiko Sakashita, Kris G. Alavattam, Paul R. Andreassen, Miguel Vidal, Haruhiko Koseki, Artem Barski, Satoshi H. Namekawa

Genes Dev. 2017 Aug 15; 31(16): 1693–1703. doi: 10.1101/gad.302000.117

PMCID:: PMC5647939

Abstract Article PDF–6.6M

Select item 33477907.

Polycomb function during oogenesis is required for mouse embryonic development

Eszter Posfai, Rico Kunzmann, Vincent Brochard, Juliette Salvaing, Erik Cabuy, Tim C. Roloff, Zichuan Liu, Mathieu Tardat, Maarten van Lohuizen, Miguel Vidal, Nathalie Beaujean, Antoine H.F.M. Peters

Genes Dev. 2012 May 1; 26(9): 920–932. doi: 10.1101/gad.188094.112

PMCID:: PMC3347790

Abstract Article PDF–1.1M

Select item 22930858.

Changes in the Distributions and Dynamics of Polycomb Repressive Complexes during Embryonic Stem Cell Differentiation

Xiaojun Ren, Claudius Vincenz, Tom K. Kerppola

Mol Cell Biol. 2008 May; 28(9): 2884–2895. Published online 2008 Mar 3. doi: 10.1128/MCB.00949-07

PMCID:: PMC2293085

Abstract Article PDF–1.1M

Select item 79194129.

Polycomb complexes redundantly maintain epidermal stem cell identity during development

Idan Cohen, Carmit Bar, Hequn Liu, Victor J. Valdes, Dejian Zhao, Phillip M. Galbo, Jr., Jose M. Silva, Haruhiko Koseki, Deyou Zheng, Elena Ezhkova

Genes Dev. 2021 Mar 1; 35(5-6): 354–366. doi: 10.1101/gad.345363.120

PMCID:: PMC7919412

Abstract Article PDF–9.0M

Select item 515966310.

Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program

Tomokatsu Ikawa, Kyoko Masuda, Takaho A. Endo, Mitsuhiro Endo, Kyoichi Isono, Yoko Koseki, Rinako Nakagawa, Kohei Kometani, Junichiro Takano, Yasutoshi Agata, Yoshimoto Katsura, Tomohiro Kurosaki, Miguel Vidal, Haruhiko Koseki, Hiroshi Kawamoto

Genes Dev. 2016 Nov 15; 30(22): 2475–2485. doi: 10.1101/gad.290593.116

PMCID:: PMC5159663

Abstract Article PDF–961K

Select item 484763911.

Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome

Stefan Schoenfelder, Robert Sugar, Andrew Dimond, Biola-Maria Javierre, Harry Armstrong, Borbala Mifsud, Emilia Dimitrova, Louise Matheson, Filipe Tavares-Cadete, Mayra Furlan-Magaril, Anne Segonds-Pichon, Wiktor Jurkowski, Steven W. Wingett, Kristina Tabbada, Simon Andrews, Bram Herman, Emily LeProust, Cameron S. Osborne, Haruhiko Koseki, Peter Fraser, Nicholas M. Luscombe, Sarah Elderkin

Nat Genet. Author manuscript; available in PMC 2016 Apr 27.

Published in final edited form as: Nat Genet. 2015 Oct; 47(10): 1179–1186. Published online 2015 Aug 31. doi: 10.1038/ng.3393

PMCID:: PMC4847639

Abstract Article PDF–2.0M

Select item 404846412.

Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation

Neil P. Blackledge, Anca M. Farcas, Takashi Kondo, Hamish W. King, Joanna F. McGouran, Lars L.P. Hanssen, Shinsuke Ito, Sarah Cooper, Kaori Kondo, Yoko Koseki, Tomoyuki Ishikura, Hannah K. Long, Thomas W. Sheahan, Neil Brockdorff, Benedikt M. Kessler, Haruhiko Koseki, Robert J. Klose

Cell. 2014 Jun 5; 157(6): 1445–1459. doi: 10.1016/j.cell.2014.05.004

PMCID:: PMC4048464

Abstract Article PDF–4.1M

Select item 397923213.

Physical and functional interaction of Rnf2 with Af9 regulates basal and aldosterone-stimulated transcription of the α-ENaC gene in a renal collecting duct cell line

Zhi-Yuan Yu, Qun Kong, Bruce C. Kone

Biosci Rep. 2013; 33(5): e00076. Prepublished online 2013 Sep 27. Published online 2013 Oct 25. doi: 10.1042/BSR20130086

PMCID:: PMC3979232

Abstract Article PDF–539K

Select item 368218714.

Polycomb Associates Genome-wide with a Specific RNA Polymerase II Variant, and Regulates Metabolic Genes in ESCs

Emily Brookes, Inês de Santiago, Daniel Hebenstreit, Kelly J. Morris, Tom Carroll, Sheila Q. Xie, Julie K. Stock, Martin Heidemann, Dirk Eick, Naohito Nozaki, Hiroshi Kimura, Jiannis Ragoussis, Sarah A. Teichmann, Ana Pombo

Cell Stem Cell. 2012 Feb 3; 10(2): 157–170. doi: 10.1016/j.stem.2011.12.017

PMCID:: PMC3682187

Abstract Article

Select item 347949515.

A noncoding RNA regulates the neurogenin1 gene locus during mouse neocortical development

Masahiro Onoguchi, Yusuke Hirabayashi, Haruhiko Koseki, Yukiko Gotoh

Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42): 16939–16944. Published online 2012 Oct 1. doi: 10.1073/pnas.1202956109

PMCID:: PMC3479495

Abstract Article PDF–1.0M

Select item 237505516.

Ubiquitin E3 Ligase Ring1b/Rnf2 of Polycomb Repressive Complex 1 Contributes to Stable Maintenance of Mouse Embryonic Stem Cells

Petra van der Stoop, Erwin A. Boutsma, Danielle Hulsman, Sonja Noback, Mike Heimerikx, Ron M. Kerkhoven, J. Willem Voncken, Lodewyk F. A. Wessels, Maarten van Lohuizen

PLoS One. 2008; 3(5): e2235. Published online 2008 May 21. doi: 10.1371/journal.pone.0002235

PMCID:: PMC2375055

Abstract Article PDF–626K

Select item 222339017.

Inactivation of the Polycomb Group Protein Ring1B Unveils an Antiproliferative Role in Hematopoietic Cell Expansion and Cooperation with Tumorigenesis Associated with Ink4a Deletion

Carmela Calés, Mónica Román-Trufero, Leticia Pavón, Iván Serrano, Teresa Melgar, Mitsuhiro Endoh, Claudia Pérez, Haruhiko Koseki, Miguel Vidal

Mol Cell Biol. 2008 Feb; 28(3): 1018–1028. Published online 2007 Nov 26. doi: 10.1128/MCB.01136-07

PMCID:: PMC2223390

Abstract Article PDF–483K

Select item 970543018.

PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment

Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, Tomohiro Miyai, Yoko Koseki, Mika Ikegaya, Mizuki Sakihara, Manabu Nakayama, Osamu Ohara, Yoshinori Hasegawa, Kosuke Hashimoto, Erik Arner, Robert J. Klose, Atsushi Iwama, Haruhiko Koseki, Tomokatsu Ikawa

Nat Commun. 2022; 13: 7159. Published online 2022 Nov 28. doi: 10.1038/s41467-022-34856-8

PMCID:: PMC9705430

Abstract Article PDF–4.0M

Select item 562591419.

Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity

Yoshihiro Omori, Shun Kubo, Tetsuo Kon, Mayu Furuhashi, Hirotaka Narita, Taro Kominami, Akiko Ueno, Ryotaro Tsutsumi, Taro Chaya, Haruka Yamamoto, Isao Suetake, Shinji Ueno, Haruhiko Koseki, Atsushi Nakagawa, Takahisa Furukawa

Proc Natl Acad Sci U S A. 2017 Sep 26; 114(39): E8264–E8273. Published online 2017 Sep 12. doi: 10.1073/pnas.1707021114

PMCID:: PMC5625914

Abstract Article PDF–1.7M

Select item 505538220.

Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice

Alessandra Rossi, Karin J. Ferrari, Andrea Piunti, SriGanesh Jammula, Fulvio Chiacchiera, Luca Mazzarella, Andrea Scelfo, Pier Giuseppe Pelicci, Diego Pasini

Sci Adv. 2016 Oct; 2(10): e1600972. Published online 2016 Oct 7. doi: 10.1126/sciadv.1600972

PMCID:: PMC5055382

Abstract Article PDF–2.0M

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