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Select item 102105131.

Ptf1a expression is necessary for correct targeting of spiral ganglion neurons within the cochlear nuclei

Karen L. Elliott, Igor Y. Iskusnykh, Victor V. Chizhikov, Bernd Fritzsch

Neurosci Lett. Author manuscript; available in PMC 2024 May 29.

Published in final edited form as: Neurosci Lett. 2023 May 29; 806: 137244. Published online 2023 Apr 11. doi: 10.1016/j.neulet.2023.137244

PMCID:: PMC10210513

Abstract Article PDF–1.6M

Select item 92031212.

Mice Lacking Cerebellar Cortex and Related Structures Show a Decrease in Slow-Wave Activity With Normal Non-REM Sleep Amount and Sleep Homeostasis

Tomoyuki Fujiyama, Henri Takenaka, Fuyuki Asano, Kazuya Miyanishi, Noriko Hotta-Hirashima, Yukiko Ishikawa, Satomi Kanno, Patricia Seoane-Collazo, Hideki Miwa, Mikio Hoshino, Masashi Yanagisawa, Hiromasa Funato

Front Behav Neurosci. 2022; 16: 910461. Published online 2022 Jun 2. doi: 10.3389/fnbeh.2022.910461

PMCID:: PMC9203121

Abstract Article PDF–2.6M

Select item 68162573.

Proteogenomic Network Analysis of Context-Specific KRAS Signaling In Mouse-to-Human Cross-Species Translation

Douglas K. Brubaker, Joao A. Paulo, Shikha Sheth, Emily J. Poulin, Olesja Popow, Brian A. Joughin, Samantha Dale Strasser, Alina Starchenko, Steven P. Gygi, Douglas A. Lauffenburger, Kevin M. Haigis

Cell Syst. Author manuscript; available in PMC 2020 Sep 25.

Published in final edited form as: Cell Syst. 2019 Sep 25; 9(3): 258–270.e6. Published online 2019 Sep 11. doi: 10.1016/j.cels.2019.07.006

PMCID:: PMC6816257

Abstract Article PDF–2.9M

Select item 60268754.

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

Brad L. Jakubison, Patrick G. Schweickert, Sarah E. Moser, Yi Yang, Hongyu Gao, Kathleen Scully, Pamela Itkin‐Ansari, Yunlong Liu, Stephen F. Konieczny

Mol Oncol. 2018 Jun; 12(7): 1104–1124. Published online 2018 May 21. doi: 10.1002/1878-0261.12314

PMCID:: PMC6026875

Abstract Article PDF–2.2M

Select item 50315395.

Regulating the dorsal neural tube expression of Ptf1a through a distal 3′ enhancer

Bishakha Mona, John M. Avila, David M. Meredith, Rahul K. Kollipara, Jane E. Johnson

Dev Biol. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Dev Biol. 2016 Oct 1; 418(1): 216–225. Published online 2016 Jun 25. doi: 10.1016/j.ydbio.2016.06.033

PMCID:: PMC5031539

Abstract Article PDF–2.3M

Select item 42834756.

Ectopic Ptf1a expression in murine ESCs potentiates endocrine differentiation and models pancreas development in vitro

Gopika Nair, Robert K. Vincent, Jon S. Odorico

Stem Cells. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Stem Cells. 2014 May; 32(5): 1195–1207. doi: 10.1002/stem.1616

PMCID:: PMC4283475

Abstract Article PDF–3.2M

Select item 25197327.

Transcriptional Autoregulation Controls Pancreatic Ptf1a Expression during Development and Adulthood

Toshihiko Masui, Galvin H. Swift, Michael A. Hale, David M. Meredith, Jane E. Johnson, Raymond J. MacDonald

Mol Cell Biol. 2008 Sep; 28(17): 5458–5468. Published online 2008 Jul 7. doi: 10.1128/MCB.00549-08

PMCID:: PMC2519732

Abstract Article PDF–1.1M

Select item 112115738.

Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas

Gareth Pollin, Angela J. Mathison, Thiago M. de Assuncao, Anju Thomas, Atefeh Zeighami, Ann Salmonson, Hongfei Liu, Guillermo Urrutia, Pallavi Vankayala, Stephen J. Pandol, Johnny C. Hong, Michael T. Zimmermann, Juan Iovanna, Victor X. Jin, Raul Urrutia, Gwen Lomberk

Front Genet. 2024; 15: 1412767. Published online 2024 Jun 14. doi: 10.3389/fgene.2024.1412767

PMCID:: PMC11211573

Abstract Article PDF–6.1M

Select item 110837589.

Cytokine CCL9 Mediates Oncogenic KRAS-Induced Pancreatic Acinar-to-Ductal Metaplasia by Promoting Reactive Oxygen Species and Metalloproteinases

Geou-Yarh Liou, Crystal J. Byrd, Peter Storz, Justin K. Messex

Int J Mol Sci. 2024 May; 25(9): 4726. Published online 2024 Apr 26. doi: 10.3390/ijms25094726

PMCID:: PMC11083758

Abstract Article PDF–3.8M

Select item 1103967110.

Activin A signaling stimulates neutrophil activation and macrophage migration in pancreatitis

Mark B. Wiley, Jessica Bauer, Valentina Alvarez, Kunaal Mehrotra, Wenxuan Cheng, Zoe Kolics, Michael Giarrizzo, Komala Ingle, Agnieszka B. Bialkowska, Barbara Jung

Sci Rep. 2024; 14: 9382. Published online 2024 Apr 23. doi: 10.1038/s41598-024-60065-y

PMCID:: PMC11039671

Abstract Article PDF–8.4M

Select item 750259311.

Acinar transformed ductal cells exhibit differential mucin expression in a tamoxifen-induced pancreatic ductal adenocarcinoma mouse model

Kavita Mallya, Dhanya Haridas, Parthasarathy Seshacharyulu, Ramesh Pothuraju, Wade M. Junker, Shiv Ram Krishn, Sakthivel Muniyan, Raghupathy Vengoji, Surinder K. Batra, Satyanarayana Rachagani

Biol Open. 2020 Sep 15; 9(9): bio052878. Published online 2020 Sep 7. doi: 10.1242/bio.052878

PMCID:: PMC7502593

Abstract Article PDF–13M

Select item 703313212.

Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury

Julie K. Bray, Ola A. Elgamal, Jinmai Jiang, Lais S. Wright, Dhruvitkumar S. Sutaria, Mohamed Badawi, Madeline G. Borcyk, Xiuli Liu, Kristianna M. Fredenburg, Martha L. Campbell-Thompson, Thomas D. Schmittgen

Cell Death Dis. 2020 Feb; 11(2): 138. Published online 2020 Feb 20. doi: 10.1038/s41419-020-2269-7

PMCID:: PMC7033132

Abstract Article PDF–6.7M

Select item 696249413.

Metformin alters the duodenal microbiome and decreases the incidence of pancreatic ductal adenocarcinoma promoted by diet-induced obesity

Tien S. Dong, Hui-Hua Chang, Meg Hauer, Venu Lagishetty, William Katzka, Enrique Rozengurt, Jonathan P. Jacobs, Guido Eibl

Am J Physiol Gastrointest Liver Physiol. 2019 Dec 1; 317(6): G763–G772. Published online 2019 Sep 23. doi: 10.1152/ajpgi.00170.2019

PMCID:: PMC6962494

Abstract Article

Select item 652480814.

Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in Kras^G12D mice

Fang Hao, Qinhong Xu, Jing Wang, Shuo Yu, Hui-Hua Chang, James Sinnett-Smith, Guido Eibl, Enrique Rozengurt

PLoS One. 2019; 14(5): e0216603. Published online 2019 May 17. doi: 10.1371/journal.pone.0216603

PMCID:: PMC6524808

Abstract Article PDF–3.3M

Select item 650653115.

The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in Kras^G12D; Pdx1-Cre (KC) mice

Ana S. Leal, Sean A. Misek, Erika M. Lisabeth, Richard R. Neubig, Karen T. Liby

Sci Rep. 2019; 9: 7072. Published online 2019 May 8. doi: 10.1038/s41598-019-43430-0

PMCID:: PMC6506531

Abstract Article PDF–1.9M

Select item 650315116.

Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma

Didier Dréau, Laura Jeffords Moore, Mike Wu, Lopa Das Roy, Lloye Dillion, Travis Porter, Rahul Puri, Noor Momin, K. Dane Wittrup, Pinku Mukherjee

Front Oncol. 2019; 9: 330. Published online 2019 Apr 30. doi: 10.3389/fonc.2019.00330

PMCID:: PMC6503151

Abstract Article PDF–3.9M

Select item 645852217.

β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis

Risheng Ye, Toshiharu Onodera, Pierre-Gilles Blanchard, Christine M. Kusminski, Victoria Esser, Rolf A. Brekken, Philipp E. Scherer

Am J Pathol. 2019 Apr; 189(4): 813–825. doi: 10.1016/j.ajpath.2019.01.002

PMCID:: PMC6458522

Abstract Article PDF–6.3M

Select item 620240618.

Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway

Morito Sakikubo, Kenichiro Furuyama, Masashi Horiguchi, Shinichi Hosokawa, Yoshiki Aoyama, Kunihiko Tsuboi, Toshihiko Goto, Koji Hirata, Toshihiko Masui, Yuval Dor, Tomoyuki Fujiyama, Mikio Hoshino, Shinji Uemoto, Yoshiya Kawaguchi

Sci Rep. 2018; 8: 15812. Published online 2018 Oct 25. doi: 10.1038/s41598-018-34093-4

PMCID:: PMC6202406

Abstract Article PDF–3.4M

Select item 607634319.

Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure

Jesse Handler, Jane Cullis, Antonina Avanzi, Emily A. Vucic, Dafna Bar-Sagi

Oncogene. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: Oncogene. 2018 Aug; 37(31): 4334–4342. Published online 2018 May 1. doi: 10.1038/s41388-018-0264-6

PMCID:: PMC6076343

Abstract Article PDF–1.2M

Select item 605464920.

Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a

Dongchang Xiao, Xiaoning Liu, Min Zhang, Min Zou, Qinqin Deng, Dayu Sun, Xuting Bian, Yulong Cai, Yanan Guo, Shuting Liu, Shengguo Li, Evelyn Shiang, Hongyu Zhong, Lin Cheng, Haiwei Xu, Kangxin Jin, Mengqing Xiang

Nat Commun. 2018; 9: 2865. Published online 2018 Jul 20. doi: 10.1038/s41467-018-05209-1

PMCID:: PMC6054649

Abstract Article PDF–9.2M

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PMC Links for Gene (Select 19213) (464)
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RecName: Full=Pancreas transcription factor 1 subunit alpha; AltName: Full=Pancr...
RecName: Full=Pancreas transcription factor 1 subunit alpha; AltName: Full=Pancreas-specific transcription factor 1a; AltName: Full=bHLH transcription factor p48; AltName: Full=p48 DNA-binding subunit of transcription factor PTF1; Short=PTF1-p48
gi|81907091|sp|Q9QX98.1|PTF1A_MOUSE

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