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Select item 83854491.

Epithelial cell transforming factor ECT2 is an important regulator of DNA double-strand break repair and genome stability

Cheng Cao, Peiyi Han, Ling Liu, Yiman Tang, Shanshan Tian, Kai Zhang, Lei Shi, Zhiqiang Liu, Dexiang Zhuo, Wenshu Ge, Wenchen Gong

J Biol Chem. 2021 Sep; 297(3): 101036. Published online 2021 Jul 31. doi: 10.1016/j.jbc.2021.101036

PMCID:: PMC8385449

Abstract Article PDF–4.0M

Select item 78939902.

ECT2 promotes lung adenocarcinoma progression through extracellular matrix dynamics and focal adhesion signaling

Zeinab Kosibaty, Yoshihiko Murata, Yuko Minami, Masayuki Noguchi, Noriaki Sakamoto

Cancer Sci. 2021 Feb; 112(2): 703–714. Published online 2020 Dec 28. doi: 10.1111/cas.14743

PMCID:: PMC7893990

Abstract Article PDF–1.6M

Select item 78706643.

ECT2 overexpression promotes the polarization of tumor-associated macrophages in hepatocellular carcinoma via the ECT2/PLK1/PTEN pathway

Dafeng Xu, Yu Wang, Jincai Wu, Zhensheng Zhang, Jiacheng Chen, Mingwei Xie, Rong Tang, Cheng Chen, Liang Chen, Shixun Lin, Xiangxiang Luo, Jinfang Zheng

Cell Death Dis. 2021 Feb; 12(2): 162. Published online 2021 Feb 8. doi: 10.1038/s41419-021-03450-z

Correction in:: Cell Death Dis. 2022 Mar; 13(3): 201.

PMCID:: PMC7870664

Abstract Article PDF–4.3M

Select item 69695004.

Structure and regulation of human epithelial cell transforming 2 protein

Mengran Chen, Han Pan, Lingfei Sun, Peng Shi, Yikan Zhang, Le Li, Yuxing Huang, Jianhui Chen, Peng Jiang, Xianyang Fang, Congying Wu, Zhucheng Chen

Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1027–1035. Published online 2019 Dec 30. doi: 10.1073/pnas.1913054117

PMCID:: PMC6969500

Abstract Article PDF–1.6M

Select item 67483695.

Oncogenic Ect2 signaling regulates rRNA synthesis in NSCLC

Verline Justilien, Kayla C. Lewis, Nicole R. Murray, Alan P. Fields

Small GTPases. 2019 Sep; 10(5): 388–394. Published online 2017 Jul 5. doi: 10.1080/21541248.2017.1335274

PMCID:: PMC6748369

Abstract Article PDF–961K

Select item 56634956.

High ECT2 expression is an independent prognostic factor for poor overall survival and recurrence-free survival in non-small cell lung adenocarcinoma

Shijie Zhou, Ping Wang, Xiaolan Su, Jingxia Chen, Hongfen Chen, Hanbing Yang, Aiping Fang, Linshen Xie, Yuqin Yao, Jinliang Yang

PLoS One. 2017; 12(10): e0187356. Published online 2017 Oct 31. doi: 10.1371/journal.pone.0187356

Correction in:: PLoS One. 2018; 13(4): e0196354.

PMCID:: PMC5663495

Abstract Article PDF–17M

Select item 55621837.

Role of Epithelial Cell Transforming Sequence 2 (ECT2) in Predicting Prognosis of Osteosarcoma

Zhiguo Chen, Jiatian Liu, Yihang Zhang

Med Sci Monit. 2017; 23: 3861–3868. Published online 2017 Aug 10. doi: 10.12659/MSM.905951

PMCID:: PMC5562183

Abstract Article PDF–799K

Select item 54123288.

Early Assessment of Colorectal Cancer by Quantifying Circulating Tumor Cells in Peripheral Blood: ECT2 in Diagnosis of Colorectal Cancer

Chih-Jung Chen, Wen-Wei Sung, Hung-Chang Chen, Yi-Jye Chern, Hui-Ting Hsu, Yueh-Min Lin, Shu-Hui Lin, Konan Peck, Kun-Tu Yeh

Int J Mol Sci. 2017 Apr; 18(4): 743. Published online 2017 Mar 31. doi: 10.3390/ijms18040743

PMCID:: PMC5412328

Abstract Article PDF–1.4M

Select item 51776049.

Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis

Kristýna Kotýnková, Kuan-Chung Su, Stephen C. West, Mark Petronczki

Cell Rep. 2016 Dec 6; 17(10): 2672–2686. Published online 2016 Dec 6. doi: 10.1016/j.celrep.2016.11.029

PMCID:: PMC5177604

Abstract Article PDF–5.0M

Select item 431780210.

ECT2 amplification and overexpression as a new prognostic biomarker for early-stage lung adenocarcinoma

Yoshihiko Murata, Yuko Minami, Reika Iwakawa, Jun Yokota, Shingo Usui, Koji Tsuta, Kouya Shiraishi, Shingo Sakashita, Kaishi Satomi, Tatsuo Iijima, Masayuki Noguchi

Cancer Sci. 2014 Apr; 105(4): 490–497. Published online 2014 Mar 19. doi: 10.1111/cas.12363

PMCID:: PMC4317802

Abstract Article PDF–1.3M

Select item 431397411.

Up-regulation of ECT2 is associated with poor prognosisn gastric cancer patients

Yi Jin, Yuhui Yu, Qinshu Shao, Yingyu Ma, Ruxuan Zhang, Haibo Yao, Yuan Xu

Int J Clin Exp Pathol. 2014; 7(12): 8724–8731. Published online 2014 Dec 1.

PMCID:: PMC4313974

Abstract Article PDF–748K

Select item 376337112.

Changes in Ect2 Localization Couple Actomyosin-Dependent Cell Shape Changes to Mitotic Progression

Helen K. Matthews, Ulysse Delabre, Jennifer L. Rohn, Jochen Guck, Patricia Kunda, Buzz Baum

Dev Cell. 2012 Aug 14; 23(2): 371–383. doi: 10.1016/j.devcel.2012.06.003

PMCID:: PMC3763371

Abstract Article PDF–1.9M

Select item 352164513.

Nonfunction of the ECT2 gene may cause renal tubulointerstitial injury leading to focal segmental glomerulosclerosis

Akane Izu, Keisuke Sugimoto, Shinsuke Fujita, Hitomi Nishi, Yutaka Takemura, Mitsuru Okada, Tsukasa Takemura

Clin Exp Nephrol. 2012; 16(6): 875–882. Published online 2012 May 3. doi: 10.1007/s10157-012-0636-0

PMCID:: PMC3521645

Abstract Article PDF–807K

Select item 299393014.

Epithelial Cell Transforming Sequence 2 in Human Oral Cancer

Manabu Iyoda, Atsushi Kasamatsu, Takashi Ishigami, Dai Nakashima, Yosuke Endo-Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa

PLoS One. 2010; 5(11): e14082. Published online 2010 Nov 29. doi: 10.1371/journal.pone.0014082

PMCID:: PMC2993930

Abstract Article PDF–415K

Select item 217419115.

Novel Functions of Ect2 in Polar Lamellipodia Formation and Polarity Maintenance during “Contractile Ring-Independent” Cytokinesis in Adherent Cells

Masamitsu Kanada, Akira Nagasaki, Taro Q.P. Uyeda

Mol Biol Cell. 2008 Jan; 19(1): 8–16. doi: 10.1091/mbc.E07-04-0370

PMCID:: PMC2174191

Abstract Article PDF–1.2M

Select item 216934516.

Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in Cytokinesis

Takashi Tatsumoto, Xiaozhen Xie, Rayah Blumenthal, Isamu Okamoto, Toru Miki

J Cell Biol. 1999 Nov 29; 147(5): 921–928. doi: 10.1083/jcb.147.5.921

PMCID:: PMC2169345

Abstract Article PDF–324K

Select item 920056917.

Integrated Analysis of ECT2 and COL17A1 as Potential Biomarkers for Pancreatic Cancer

Wen-liang Huang, Shu-fen Wu, Xiao Huang, Shan Zhou

Dis Markers. 2022; 2022: 9453549. Published online 2022 Jun 8. doi: 10.1155/2022/9453549

PMCID:: PMC9200569

Abstract Article PDF–7.1M

Select item 673464818.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

Avais M. Daulat, Pascal Finetti, Diego Revinski, Mônica Silveira Wagner, Luc Camoin, Stéphane Audebert, Daniel Birnbaum, Laurent Kodjabachian, Jean-Paul Borg, François Bertucci

Br J Cancer. 2019 Apr 30; 120(9): 931–940. Published online 2019 Apr 11. doi: 10.1038/s41416-019-0448-z

PMCID:: PMC6734648

Abstract Article PDF–1.4M

Select item 549813119.

P53 and Protein Phosphorylation Regulate the Oncogenic Role of Epithelial Cell Transforming 2 (ECT2)

Yan Chen, Ping Tian, Yi Liu

Med Sci Monit. 2017; 23: 3154–3160. Published online 2017 Jun 27. doi: 10.12659/MSM.905388

PMCID:: PMC5498131

Abstract Article PDF–723K

Select item 502962520.

Meta-analysis of transcriptome data identifies a novel 5-gene pancreatic adenocarcinoma classifier

Manoj K. Bhasin, Kenneth Ndebele, Octavian Bucur, Eric U. Yee, Hasan H. Otu, Jessica Plati, Andrea Bullock, Xuesong Gu, Eduardo Castan, Peng Zhang, Robert Najarian, Maria S. Muraru, Rebecca Miksad, Roya Khosravi-Far, Towia A. Libermann

Oncotarget. 2016 Apr 26; 7(17): 23263–23281. Published online 2016 Mar 16. doi: 10.18632/oncotarget.8139