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Select item 110728771.

PAI-1 production by reactive astrocytes drives tissue dysfibrinolysis in multiple sclerosis models

Héloïse Lebas, Sylvaine Guérit, Audrey Picot, Anne Cécile Boulay, Antoine Fournier, Denis Vivien, Martine Cohen Salmon, Fabian Docagne, Isabelle Bardou

Cell Mol Life Sci. 2022 Jun; 79(6): 323. Published online 2022 May 28. doi: 10.1007/s00018-022-04340-z

PMCID:: PMC11072877

Abstract Article PDF–16M

Select item 103757812.

PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

Gibran Ali, Mo Zhang, Jianjun Chang, Runzhen Zhao, Yang Jin, Jiwang Zhang, Hong-Long Ji

Stem Cell Res Ther. 2023; 14: 185. Published online 2023 Jul 27. doi: 10.1186/s13287-023-03414-4

PMCID:: PMC10375781

Abstract Article PDF–1.5M

Select item 96029393.

Wnt5a/β-catenin axis is involved in the downregulation of AT2 lineage by PAI-1

Krishan G. Jain, Runzhen Zhao, Yang Liu, Xuan Guo, Guohua Yi, Hong-Long Ji

Am J Physiol Lung Cell Mol Physiol. 2022 Nov 1; 323(5): L515–L524. Published online 2022 Sep 13. doi: 10.1152/ajplung.00202.2022

PMCID:: PMC9602939

Abstract Article

Select item 93060994.

Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis

Xueshu Chen, Wei Chen, Yan Zhao, Qinrong Wang, Wenling Wang, Yining Xiang, Hang Yuan, Yuan Xie, Jianjiang Zhou

J Transl Med. 2022; 20: 322. Published online 2022 Jul 21. doi: 10.1186/s12967-022-03537-x

PMCID:: PMC9306099

Abstract Article PDF–13M

Select item 87452855.

Role of Macrophages and Plasminogen Activator Inhibitor-1 in Delayed Bone Repair Induced by Glucocorticoids in Mice

Kiyotaka Okada, Naoyuki Kawao, Daisho Nakai, Rei Wakabayashi, Yoshitaka Horiuchi, Katsumi Okumoto, Shinji Kurashimo, Yoshimasa Takafuji, Osamu Matsuo, Hiroshi Kaji

Int J Mol Sci. 2022 Jan; 23(1): 478. Published online 2022 Jan 1. doi: 10.3390/ijms23010478

PMCID:: PMC8745285

Abstract Article PDF–2.4M

Select item 73648186.

Transcriptomic Analysis of Cellular Pathways in Healing Flexor Tendons of Plasminogen Activator Inhibitor 1 (PAI-1/Serpine1) Null Mice

Margaret A. T. Freeberg, Anas Easa, Jacquelyn A. Lillis, Danielle S.W. Benoit, Andre J. van Wijnen, Hani A. Awad

J Orthop Res. Author manuscript; available in PMC 2020 Jul 16.

Published in final edited form as: J Orthop Res. 2020 Jan; 38(1): 43–58. Published online 2019 Sep 1. doi: 10.1002/jor.24448

PMCID:: PMC7364818

Abstract Article PDF–1.0M

Select item 71536567.

Transplantation of adipose tissue lacking PAI-1 improves glucose tolerance and attenuates cardiac metabolic abnormalities in high-fat diet-induced obesity

Sijing Liu, Yi Li, Xin Fan, Kai Li, Chunrong Xu, Liping Zhang, Mao Luo, Liqun Wang, Rong Li, Jianbo Wu

Adipocyte. 2020; 9(1): 170–178. Published online 2020 Apr 9. doi: 10.1080/21623945.2020.1748961

PMCID:: PMC7153656

Abstract Article PDF–1.3M

Select item 68585818.

Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

Derek Klarin, Emma Busenkell, Renae Judy, Julie Lynch, Michael Levin, Jeffery Haessler, Krishna Aragam, Mark Chaffin, Mary Haas, Sara Lindström, Themistocles L. Assimes, Jie Huang, Kyung Min Lee, Qing Shao, Jennifer E. Huffman, Christopher Kabrhel, Yunfeng Huang, Yan V. Sun, Marijana Vujkovic, Danish Saleheen, Donald R. Miller, Peter Reaven, Scott DuVall, William E. Boden, Saiju Pyarajan, Alex P. Reiner, David-Alexandre Trégouët, Peter Henke, Charles Kooperberg, J. Michael Gaziano, John Concato, Daniel J. Rader, Kelly Cho, Kyong-Mi Chang, Peter W.F. Wilson, Nicholas L. Smith, Christopher J. O’Donnell, Philip S. Tsao, Sekar Kathiresan, Andrea Obi, Scott M. Damrauer, Pradeep Natarajan, INVENT Consortium, VA Million Veteran Program

Nat Genet. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Nat Genet. 2019 Nov; 51(11): 1574–1579. Published online 2019 Nov 1. doi: 10.1038/s41588-019-0519-3

PMCID:: PMC6858581

Abstract Article PDF–1.0M

Select item 60461909.

Mast Cell-Derived PAI-1 Promotes Airway Inflammation and Remodeling in a Murine Model of Asthma

Ara Jo, Sun H. Lee, Dong-Young Kim, Seung-Jae Hong, Michael N Teng, Narasaiah Kolliputi, Richard F. Lockey, Robert P. Schleimer, Seong H Cho

J Allergy Clin Immunol. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: J Allergy Clin Immunol. 2018 Jul; 142(1): 294–297.e5. Published online 2018 Mar 2. doi: 10.1016/j.jaci.2018.01.040

Correction in:: J Allergy Clin Immunol. 2018 Nov; 142(5): 1678.

PMCID:: PMC6046190

Article PDF–829K

Select item 591988010.

PAI1 mediates fibroblast–mast cell interactions in skin fibrosis

Neha Pincha, Edries Yousaf Hajam, Krithika Badarinath, Surya Prakash Rao Batta, Tafheem Masudi, Rakesh Dey, Peter Andreasen, Toshiaki Kawakami, Rekha Samuel, Renu George, Debashish Danda, Paul Mazhuvanchary Jacob, Colin Jamora

J Clin Invest. 2018 May 1; 128(5): 1807–1819. Published online 2018 Mar 26. doi: 10.1172/JCI99088

PMCID:: PMC5919880

Abstract Article PDF–14M

Select item 589557811.

Serpine1 Knockdown Enhances MMP Activity after Flexor Tendon Injury in Mice: Implications for Adhesions Therapy

Margaret A. T. Freeberg, Youssef M. Farhat, Anas Easa, Jacob G. Kallenbach, Dominic W. Malcolm, Mark R. Buckley, Danielle S. W. Benoit, Hani A. Awad

Sci Rep. 2018; 8: 5810. Published online 2018 Apr 11. doi: 10.1038/s41598-018-24144-1

PMCID:: PMC5895578

Abstract Article PDF–3.5M

Select item 578440012.

Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis

Panagiotis Flevaris, Sadiya S. Khan, Mesut Eren, Adam J. T. Schuldt, Sanjiv J. Shah, Daniel C. Lee, Sweta Gupta, Amy D. Shapiro, Paul W. Burridge, Asish K. Ghosh, Douglas E. Vaughan

Circulation. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Circulation. 2017 Aug 15; 136(7): 664–679. Published online 2017 Jun 6. doi: 10.1161/CIRCULATIONAHA.117.028145

PMCID:: PMC5784400

Abstract Article PDF–1.0M

Select item 559451413.

Plasminogen activator inhibitor-1 deficiency enhances subchondral osteopenia after induction of osteoarthritis in mice

Akihiro Moritake, Naoyuki Kawao, Kiyotaka Okada, Kohei Tatsumi, Masayoshi Ishida, Katsumi Okumoto, Osamu Matsuo, Masao Akagi, Hiroshi Kaji

BMC Musculoskelet Disord. 2017; 18: 392. Published online 2017 Sep 11. doi: 10.1186/s12891-017-1752-5

PMCID:: PMC5594514

Abstract Article PDF–1.3M

Select item 544513814.

Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury

Winfried Neuhaus, Tobias Krämer, Anja Neuhoff, Christina Gölz, Serge C. Thal, Carola Y. Förster

Front Mol Neurosci. 2017; 10: 149. Published online 2017 May 26. doi: 10.3389/fnmol.2017.00149

PMCID:: PMC5445138

Abstract Article PDF–3.5M

Select item 510227115.

Pharmacological Targeting of Plasminogen Activator Inhibitor-1 Decreases Vascular Smooth Muscle Cell Migration and Neointima Formation

Yan Ji, Zhen Weng, Philip Fish, Neha Goyal, Mao Luo, Samantha P. Myears, Tammy L. Strawn, Bysani Chandrasekar, Jianbo Wu, William P. Fay

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Nov; 36(11): 2167–2175. Published online 2016 Sep 22. doi: 10.1161/ATVBAHA.116.308344

PMCID:: PMC5102271

Abstract Article PDF–1.6M

Select item 438468716.

Plasminogen activator inhibitor 1, fibroblast apoptosis resistance, and aging-related susceptibility to lung fibrosis

Wen-Tan Huang, Hasina Akhter, Chunsun Jiang, Mark MacEwen, Qiang Ding, Veena Antony, Victor John Thannickal, Rui-Ming Liu

Exp Gerontol. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Exp Gerontol. 2015 Jan; 61: 62–75. Published online 2014 Nov 28. doi: 10.1016/j.exger.2014.11.018

PMCID:: PMC4384687

Abstract Article PDF–4.9M

Select item 421482017.

Effects of a High-Fat Diet on Spontaneous Metastasis of Lewis Lung Carcinoma in Plasminogen Activator Inhibitor-1 Deficient and Wild-Type Mice

Lin Yan, Lana C. DeMars

PLoS One. 2014; 9(10): e110869. Published online 2014 Oct 30. doi: 10.1371/journal.pone.0110869

Correction in:: PLoS One. 2015; 10(3): e0118115.

PMCID:: PMC4214820

Abstract Article PDF–306K

Select item 420673718.

Nocturnal Light Exposure Alters Hepatic Pai-1 Expression by Stimulating the Adrenal Pathway in C3H Mice

Yoshiki Aoshima, Hiroyuki Sakakibara, Taka-aki Suzuki, Shunsuke Yamazaki, Kayoko Shimoi

Exp Anim. 2014; 63(3): 331–338. Published online 2014 Aug 22. doi: 10.1538/expanim.63.331

PMCID:: PMC4206737

Abstract Article PDF–781K

Select item 396526919.

Peptidergic Regulation of Plasminogen Activator Inhibitor-1 Gene Expression In Vivo

N.A. Gingles, H. Bai, L.A. Miles, R.J. Parmer

J Thromb Haemost. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Thromb Haemost. 2013 Sep; 11(9): 1707–1715. doi: 10.1111/jth.12333

PMCID:: PMC3965269

Abstract Article PDF–2.5M

Select item 393095420.

Plasminogen Activator Inhibitor-1 Deficiency Augments Visceral Mesothelial Organization, Intrapleural Coagulation, and Lung Restriction in Mice with Carbon Black/Bleomycin–Induced Pleural Injury

Torry A. Tucker, Ann Jeffers, Alexia Alvarez, Shuzi Owens, Kathleen Koenig, Brandon Quaid, Andrey A. Komissarov, Galina Florova, Hema Kothari, Usha Pendurthi, L. Vijaya Mohan Rao, Steven Idell

Am J Respir Cell Mol Biol. 2014 Feb; 50(2): 316–327. doi: 10.1165/rcmb.2013-0300OC

PMCID:: PMC3930954

Abstract Article PDF–1.8M

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