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Select item 45404281.

Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow

Kentaro Yoshioka, Akihisa Oda, Chihiro Notsu, Takafumi Ohtsuka, Yasuhiro Kawai, Sadafumi Suzuki, Takuro Nakamura, Yo Mabuchi, Yumi Matsuzaki, Ryo Goitsuka

PLoS One. 2015; 10(8): e0136107. Published online 2015 Aug 18. doi: 10.1371/journal.pone.0136107

PMCID:: PMC4540428

Abstract Article PDF–1.9M

Select item 43952332.

ChIP-Seq and RNA-Seq Analyses Identify Components of the Wnt and Fgf Signaling Pathways as Prep1 Target Genes in Mouse Embryonic Stem Cells

Audrey Laurent, Manuela Calabrese, Hans-Jörg Warnatz, Marie-Laure Yaspo, Vsevolod Tkachuk, Miguel Torres, Francesco Blasi, Dmitry Penkov

PLoS One. 2015; 10(4): e0122518. Published online 2015 Apr 13. doi: 10.1371/journal.pone.0122518

PMCID:: PMC4395233

Abstract Article PDF–1.2M

Select item 41694583.

Prep1 (pKnox1) Regulates Mouse Embryonic HSC Cycling and Self-Renewal Affecting the Stat1-Sca1 IFN-Dependent Pathway

Livia Modica, Giorgio Iotti, Annalisa D’Avola, Francesco Blasi

PLoS One. 2014; 9(9): e107916. Published online 2014 Sep 18. doi: 10.1371/journal.pone.0107916

PMCID:: PMC4169458

Abstract Article PDF–5.1M

Select item 39112944.

Pknox1/Prep1 Regulates Mitochondrial Oxidative Phosphorylation Components in Skeletal Muscle

Timo Kanzleiter, Michaela Rath, Dmitry Penkov, Dmytro Puchkov, Nadja Schulz, Francesco Blasi, Annette Schürmann

Mol Cell Biol. 2014 Jan; 34(2): 290–298. doi: 10.1128/MCB.01232-13

PMCID:: PMC3911294

Abstract Article PDF–1.4M

Select item 28879405.

Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress

Nicola Micali, Elena Longobardi, Giorgio Iotti, Carmelo Ferrai, Laura Castagnaro, Mario Ricciardi, Francesco Blasi, Massimo P. Crippa

Nucleic Acids Res. 2010 Jun; 38(11): 3595–3604. Published online 2010 Jan 27. doi: 10.1093/nar/gkq019

PMCID:: PMC2887940

Abstract Article PDF–3.6M

Select item 56860656.

Prep1 prevents premature adipogenesis of mesenchymal progenitors

Giorgia Maroni, Vsevolod A. Tkachuk, Alexander Egorov, Marco J. Morelli, Raffaele Luongo, Elena Levantini, Francesco Blasi, Maria Cristina Magli, Dmitry Penkov

Sci Rep. 2017; 7: 15573. Published online 2017 Nov 14. doi: 10.1038/s41598-017-15828-1

PMCID:: PMC5686065

Abstract Article PDF–2.3M

Select item 55278987.

Prep1 (pKnox1)‐deficiency leads to spontaneous tumor development in mice and accelerates EμMyc lymphomagenesis: A tumor suppressor role for Prep1

E. Longobardi, G. Iotti, P. Di Rosa, S. Mejetta, F. Bianchi, L.C. Fernandez-Diaz, N. Micali, P. Nuciforo, E. Lenti, M. Ponzoni, C. Doglioni, M. Caniatti, P.P. Di Fiore, F. Blasi

Mol Oncol. 2010 Apr; 4(2): 126–134. Published online 2010 Jan 7. doi: 10.1016/j.molonc.2010.01.001

PMCID:: PMC5527898

Abstract Article PDF–1.0M

Select item 31419388.

Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability

Giorgio Iotti, Elena Longobardi, Silvia Masella, Leila Dardaei, Francesca De Santis, Nicola Micali, Francesco Blasi

Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29): E314–E322. Published online 2011 Jun 29. doi: 10.1073/pnas.1105216108

PMCID:: PMC3141938

Abstract Article PDF–1.5M

Select item 26438149.

Prep1 Directly Regulates the Intrinsic Apoptotic Pathway by Controlling Bcl-X_L Levels

Nicola Micali, Carmelo Ferrai, Luis C. Fernandez-Diaz, Francesco Blasi, Massimo P. Crippa

Mol Cell Biol. 2009 Mar; 29(5): 1143–1151. Published online 2008 Dec 22. doi: 10.1128/MCB.01273-08

PMCID:: PMC2643814

Abstract Article PDF–1.1M

Select item 254692810.

Prep1 Deficiency Induces Protection from Diabetes and Increased Insulin Sensitivity through a p160-Mediated Mechanism

Francesco Oriente, Luis Cesar Fernandez Diaz, Claudia Miele, Salvatore Iovino, Silvia Mori, Victor Manuel Diaz, Giancarlo Troncone, Angela Cassese, Pietro Formisano, Francesco Blasi, Francesco Beguinot

Mol Cell Biol. 2008 Sep; 28(18): 5634–5645. Published online 2008 Jul 21. doi: 10.1128/MCB.00117-08

PMCID:: PMC2546928

Abstract Article PDF–1.1M

Select item 241340811.

Cytosolic Sequestration of Prep1 Influences Early Stages of T Cell Development

Dmitry Penkov, Martina Palazzolo, Anna Mondino, Francesco Blasi

PLoS One. 2008; 3(6): e2424. Published online 2008 Jun 18. doi: 10.1371/journal.pone.0002424

PMCID:: PMC2413408

Abstract Article PDF–392K

Select item 131696912.

Involvement of Prep1 in the αβ T-Cell Receptor T-Lymphocytic Potential of Hematopoietic Precursors

Dmitri Penkov, Patrizia Di Rosa, Luis Fernandez Diaz, Veronica Basso, Elisabetta Ferretti, Fabio Grassi, Anna Mondino, Francesco Blasi

Mol Cell Biol. 2005 Dec; 25(24): 10768–10781. doi: 10.1128/MCB.25.24.10768-10781.2005

PMCID:: PMC1316969

Abstract Article PDF–526K

Select item 14070313.

Identification of Homeodomain Proteins, PBX1 and PREP1, Involved in the Transcription of Murine Leukemia Virus

Sheng-Hao Chao, John R. Walker, Sumit K. Chanda, Nathanael S. Gray, Jeremy S. Caldwell

Mol Cell Biol. 2003 Feb; 23(3): 831–841. doi: 10.1128/MCB.23.3.831-841.2003

PMCID:: PMC140703

Abstract Article PDF–240K

Select item 630217414.

Transcription factor Sp2 potentiates binding of the TALE homeoproteins Pbx1:Prep1 and the histone-fold domain protein Nf-y to composite genomic sites

Sara Völkel, Bastian Stielow, Florian Finkernagel, Dana Berger, Thorsten Stiewe, Andrea Nist, Guntram Suske

J Biol Chem. 2018 Dec 14; 293(50): 19250–19262. Published online 2018 Oct 18. doi: 10.1074/jbc.RA118.005341

PMCID:: PMC6302174

Abstract Article PDF–2.9M

Select item 606122015.

Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling

Serena Ricci, Davide Viggiano, Ilaria Cimmino, Giuseppe Perruolo, Serena Cabaro, Antonietta Liotti, Francesca Fiory, Rosa Spinelli, Angelina Di Carlo, Francesco Beguinot, Pietro Formisano, Francesco Oriente

Mol Neurobiol. 2018; 55(8): 6801–6815. Published online 2018 Jan 18. doi: 10.1007/s12035-018-0873-7