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Items: 1 to 20 of 64

1.
Furin Regulates the Alveolarization of Neonatal Lungs in a Mouse Model of Hyperoxic Lung Injury
Shin Kato, Osuke Iwata, Hiroyuki Kato, Satoko Fukaya, Yukari Imai, Shinji Saitoh
Biomolecules. 2023 Nov; 13(11): 1656. Published online 2023 Nov 16. doi: 10.3390/biom13111656
PMCID:
PMC10669361
AbstractArticlePDF–3.0M
2.
The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
Zhanfeng Liang, Zhaoqi Zhang, Qian Zhang, Xue Dong, Xiaofeng Yang, Jiayu Zhang, Tong Lei, John W.M. Creemers, Baojun Zhang, Yong Zhao
iScience. 2022 Oct 21; 25(10): 105233. Published online 2022 Sep 28. doi: 10.1016/j.isci.2022.105233
PMCID:
PMC9579486
AbstractArticlePDF–5.8M
3.
Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells
Zsuzsanna Ortutay, Anna Grönholm, Melina Laitinen, Melinda Keresztes-Andrei, Ismail Hermelo, Marko Pesu
Front Immunol. 2021; 12: 630389. Published online 2021 Feb 18. doi: 10.3389/fimmu.2021.630389
PMCID:
PMC7930619
AbstractArticlePDF–2.1M
4.
Myeloid cell expressed proprotein convertase FURIN attenuates inflammation
Zuzet Martinez Cordova, Anna Grönholm, Ville Kytölä, Valentina Taverniti, Sanna Hämäläinen, Saara Aittomäki, Wilhelmiina Niininen, Ilkka Junttila, Antti Ylipää, Matti Nykter, Marko Pesu
Oncotarget. 2016 Aug 23; 7(34): 54392–54404. Published online 2016 Aug 5. doi: 10.18632/oncotarget.11106
PMCID:
PMC5342350
AbstractArticlePDF–2.9M
5.
Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death
WooJin Kim, Rachid Essalmani, Dorota Szumska, John W. M. Creemers, Anton J. M. Roebroek, Pedro D'Orleans-Juste, Shoumo Bhattacharya, Nabil G. Seidah, Annik Prat
Mol Cell Biol. 2012 Sep; 32(17): 3382–3391. doi: 10.1128/MCB.06331-11
PMCID:
PMC3422005
AbstractArticlePDF–3.3M
6.
T cell-expressed proprotein convertase furin is essential for maintenance of peripheral tolerance
Marko Pesu, Wendy T. Watford, Lai Wei, Lili Xu, Ivan Fuss, Warren Strober, John Andersson, Ethan Shevach, Martha Quezado, Anton Roebroek, Yasmine Belkaid, John Creemers, John J. O’Shea
Nature. Author manuscript; available in PMC 2009 Oct 6.
Published in final edited form as: Nature. 2008 Sep 11; 455(7210): 246–250. doi: 10.1038/nature07210
PMCID:
PMC2758057
AbstractArticlePDF–3.1M
7.
FURIN AT THE CUTTING EDGE: FROM PROTEIN TRAFFIC TO EMBRYOGENESIS AND DISEASE
Gary Thomas
Nat Rev Mol Cell Biol. Author manuscript; available in PMC 2007 Sep 4.
Published in final edited form as: Nat Rev Mol Cell Biol. 2002 Oct; 3(10): 753–766. doi: 10.1038/nrm934
PMCID:
PMC1964754
AbstractArticlePDF–769K
8.
Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice
Ilaria Coppola, Bas Brouwers, Sandra Meulemans, Bruno Ramos-Molina, John W. M. Creemers
Int J Mol Sci. 2021 Jun; 22(12): 6344. Published online 2021 Jun 14. doi: 10.3390/ijms22126344
PMCID:
PMC8231939
AbstractArticlePDF–2.0M
9.
In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23
Omar Al Rifai, Delia Susan-Resiga, Rachid Essalmani, John W. M. Creemers, Nabil G. Seidah, Mathieu Ferron
Front Endocrinol (Lausanne) 2021; 12: 690681. Published online 2021 Jun 4. doi: 10.3389/fendo.2021.690681
PMCID:
PMC8213403
AbstractArticlePDF–6.4M
10.
STAT6 and Furin Are Successive Triggers for the Production of TGFβ by T Cells
Yue Li, Weiren Liu, Xiaqun Guan, Jamie Truscott, John W. Creemers, Hung-Lin Chen, Marko Pesu, Rami G. El Abiad, Bahri Karacay, Joseph F. Urban, Jr, David E. Elliott, Mark H. Kaplan, Bruce R. Blazar, M. Nedim Ince
J Immunol. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: J Immunol. 2018 Nov 1; 201(9): 2612–2623. Published online 2018 Sep 28. doi: 10.4049/jimmunol.1700808
PMCID:
PMC6200631
AbstractArticlePDF–2.1M
11.
Influence of a Coronary Artery Disease–Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior
Guojun Zhao, Wei Yang, Jingchun Wu, Bairu Chen, Xu Yang, Junhui Chen, David G. McVey, Catherine Andreadi, Peng Gong, Tom R. Webb, Nilesh J. Samani, Shu Ye
Arterioscler Thromb Vasc Biol. 2018 Aug; 38(8): 1837–1844. Published online 2018 Jul 5. doi: 10.1161/ATVBAHA.118.311030
PMCID:
PMC6092112
AbstractArticlePDF–1.0M
12.
Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice
Tie-Gang Meng, Meng-Wen Hu, Xue-Shan Ma, Lin Huang, Qiu-Xia Liang, Yue Yuan, Yi Hou, Hongmei Wang, Heide Schatten, Zhen-Bo Wang, Qing-Yuan Sun
Cell Death Dis. 2017 Jun; 8(6): e2846. Published online 2017 Jun 1. doi: 10.1038/cddis.2017.231
PMCID:
PMC5520891
AbstractArticlePDF–7.1M
13.
The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion
Patricia Jaaks, Valentina D’Alessandro, Nicole Grob, Sina Büel, Katarina Hajdin, Beat W. Schäfer, Michele Bernasconi
PLoS One. 2016; 11(8): e0161396. Published online 2016 Aug 22. doi: 10.1371/journal.pone.0161396
PMCID:
PMC4993484
AbstractArticlePDF–2.7M
14.
Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth
Jeroen Declercq, Bas Brouwers, Vincent P. E. G. Pruniau, Pieter Stijnen, Krizia Tuand, Sandra Meulemans, Annik Prat, Nabil G. Seidah, Abdel-Majid Khatib, John W. M. Creemers
Biomed Res Int. 2015; 2015: 148651. Published online 2015 Jun 8. doi: 10.1155/2015/148651
PMCID:
PMC4475760
AbstractArticlePDF–1.4M
15.
Proprotein Convertase Subtilisin/Kexin Type 3 Promotes Adipose Tissue-Driven Macrophage Chemotaxis and Is Increased in Obesity
Kai Kappert, Heike Meyborg, Jan Fritzsche, Daniel Urban, Janine Krüger, Ernst Wellnhofer, Ulrich Kintscher, Eckart Fleck, Philipp Stawowy
PLoS One. 2013; 8(8): e70542. Published online 2013 Aug 6. doi: 10.1371/journal.pone.0070542
PMCID:
PMC3735592
AbstractArticlePDF–1.4M
16.
Enhanced UV-Induced Skin Carcinogenesis in Transgenic Mice Overexpressing Proprotein Convertases
Jian Fu, Daniel E Bassi, Jirong Zhang, Tianyu Li, Kathy Q Cai, Courtney Lyons Testa, Emmanuelle Nicolas, Andres J Klein-Szanto
Neoplasia. 2013 Feb; 15(2): 169–179. doi: 10.1593/neo.121846
PMCID:
PMC3579319
AbstractArticlePDF–2.2M
17.
Role of furin in granular acidification in the endocrine pancreas: Identification of the V-ATPase subunit Ac45 as a candidate substrate
Els Louagie, Neil A. Taylor, Daisy Flamez, Anton J. M. Roebroek, Nicholas A. Bright, Sandra Meulemans, Roel Quintens, Pedro L. Herrera, Frans Schuit, Wim J. M. Van de Ven, John W. M. Creemers
Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34): 12319–12324. Published online 2008 Aug 19. doi: 10.1073/pnas.0800340105
PMCID:
PMC2527909
AbstractArticlePDF–677K
18.
Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner
Meng Chen, Meng-Hang Wang, Xue-Gang Shen, Hao Liu, Yu-Yuan Zhang, Jin-Mei Peng, Fandan Meng, Tong-Yun Wang, Yuan-Zhe Bai, Ming-Xia Sun, Zhi-Jun Tian, Xin Yin, Xue-Hui Cai, Yan-Dong Tang
J Virol. 2022 Oct; 96(20): e01318-22. Published online 2022 Sep 29. doi: 10.1128/jvi.01318-22
PMCID:
PMC9599266
AbstractArticlePDF–3.3M
19.
The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans
Omar Al Rifai, Catherine Julien, Julie Lacombe, Denis Faubert, Erandi Lira-Navarrete, Yoshiki Narimatsu, Henrik Clausen, Mathieu Ferron
eLife. 2020; 9: e61174. Published online 2020 Dec 7. doi: 10.7554/eLife.61174
PMCID:
PMC7822592
AbstractArticlePDF–2.6M
20.
FURIN inhibition reduces vascular remodeling and atherosclerotic lesion progression in mice
Gopala K. Yakala, Hector A. Cabrera-Fuentes, Gustavo E. Crespo-Avilan, Chutima Rattanasopa, Alexandrina Burlacu, Benjamin L. George, Kaviya Anand, David Castano Mayan, Maria Corliano, Sauri Hernández-Reséndiz, Zihao Wu, Anne M.K. Schwerk, Amberlyn L.J. Tan, Laia Trigueros-Motos, Raphael Chevre, Tricia Chua, Robert Kleemann, Elisa A. Liehn, Derek J. Hausenloy, Sujoy Ghosh, Roshni R. Singaraja
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Mar; 39(3): 387–401. doi: 10.1161/ATVBAHA.118.311903
PMCID:
PMC6393193
AbstractArticlePDF–2.8M

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