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Select item 85773181.

Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma

Nicole M. Anderson, Xiaodan Qin, Jennifer M. Finan, Andrew Lam, Jacob Athoe, Rindert Missiaen, Nicolas Skuli, Annie Kennedy, Amandeep S. Saini, Ting Tao, Shizhen Zhu, Itzhak Nissim, A. Thomas Look, Guoliang Qing, M. Celeste Simon, Hui Feng

Cancer Res. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Cancer Res. 2021 Sep 1; 81(17): 4417–4430. Published online 2021 Jul 7. doi: 10.1158/0008-5472.CAN-20-2153

PMCID:: PMC8577318

Abstract Article PDF–1.3M

Select item 1621512.

Truncated product of the bifunctional DLST gene involved in biogenesis of the respiratory chain

Takashi Kanamori, Kiyomi Nishimaki, Sadamitsu Asoh, Yoshitomo Ishibashi, Iichiro Takata, Tomoko Kuwabara, Kazunari Taira, Haruyasu Yamaguchi, Shiro Sugihara, Tsuneo Yamazaki, Yasuo Ihara, Kyoko Nakano, Sadayuki Matuda, Shigeo Ohta

EMBO J. 2003 Jun 16; 22(12): 2913–2923. doi: 10.1093/emboj/cdg299

PMCID:: PMC162151

Abstract Article PDF–360K

Select item 64517333.

Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas

Laura Remacha, David Pirman, Christopher E. Mahoney, Javier Coloma, Bruna Calsina, Maria Currás-Freixes, Rocío Letón, Rafael Torres-Pérez, Susan Richter, Guillermo Pita, Belén Herráez, Giovanni Cianchetta, Emiliano Honrado, Lorena Maestre, Miguel Urioste, Javier Aller, Óscar García-Uriarte, María Ángeles Gálvez, Raúl M. Luque, Marcos Lahera, Cristina Moreno-Rengel, Graeme Eisenhofer, Cristina Montero-Conde, Cristina Rodríguez-Antona, Óscar Llorca, Gromoslaw A. Smolen, Mercedes Robledo, Alberto Cascón

Am J Hum Genet. 2019 Apr 4; 104(4): 651–664. Published online 2019 Mar 28. doi: 10.1016/j.ajhg.2019.02.017

Correction in:: Am J Hum Genet. 2019 May 2; 104(5): 1008–1010.

PMCID:: PMC6451733

Abstract Article PDF–2.3M

Select item 64114474.

Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells

Yongmei Feng, E. Hampton Sessions, Fan Zhang, Fuqiang Ban, Veronica Placencio-Hickok, Chen-Ting Ma, Fu-Yue Zeng, Ian Pass, David B. Terry, Gregory Cadwell, Laurie A. Bankston, Robert C. Liddington, Thomas D.Y. Chung, Anthony B. Pinkerton, Eduard Sergienko, Martin Gleave, Neil Bhowmick, Michael R. Jackson, Artem Cherkasov, Ze’ev A. Ronai

Cancer Lett. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Lett. 2019 May 1; 449: 145–162. Published online 2019 Feb 14. doi: 10.1016/j.canlet.2019.02.012

PMCID:: PMC6411447

Abstract Article PDF–1.5M

Select item 48895315.

The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis

NM Anderson, D Li, HL Peng, FJF Laroche, MR Mansour, E Gjini, M Aioub, DJ Helman, JE Roderick, T Cheng, I Harrold, Y Samaha, L Meng, A Amsterdam, DS Neuberg, TT Denton, T Sanda, MA Kelliher, A Singh, AT Look, H Feng

Leukemia. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Leukemia. 2016 Jun; 30(6): 1365–1374. Published online 2016 Feb 15. doi: 10.1038/leu.2016.26

PMCID:: PMC4889531

Abstract Article PDF–2.4M

Select item 36593556.

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

Gergely Kiss, Csaba Konrad, Judit Doczi, Anatoly A. Starkov, Hibiki Kawamata, Giovanni Manfredi, Steven F. Zhang, Gary E. Gibson, M. Flint Beal, Vera Adam-Vizi, Christos Chinopoulos

FASEB J. 2013 Jun; 27(6): 2392–2406. doi: 10.1096/fj.12-220202

PMCID:: PMC3659355

Abstract Article

Select item 58414527.

KAT2A coupled with the a-KGDH complex acts as a histone H3 succinyltransferase

Yugang Wang, Yusong R. Guo, Ke Liu, Zheng Yin, Rui Liu, Yan Xia, Lin Tan, Peiying Yang, Jong-Ho Lee, Xin-jian Li, David Hawke, Yanhua Zheng, Xu Qian, Jianxin Lyu, Jie He, Dongming Xing, Yizhi Jane Tao, Zhimin Lu

Nature. Author manuscript; available in PMC 2018 Mar 7.

Published in final edited form as: Nature. 2017 Dec 14; 552(7684): 273–277. Published online 2017 Dec 6. doi: 10.1038/nature25003

PMCID:: PMC5841452

Abstract Article PDF–3.7M

Select item 63685398.

A network of chaperones prevents and detects failures in membrane protein lipid bilayer integration

João P. L. Coelho, Matthias Stahl, Nicolas Bloemeke, Kevin Meighen-Berger, Carlos Piedrafita Alvira, Zai-Rong Zhang, Stephan A. Sieber, Matthias J. Feige

Nat Commun. 2019; 10: 672. Published online 2019 Feb 8. doi: 10.1038/s41467-019-08632-0

Correction in:: Nat Commun. 2019; 10: 1908.

PMCID:: PMC6368539

Abstract Article PDF–1.6M

Select item 27540759.

Protein kinase DYRK2 is an E3-ligase specific molecular assembler

Subbareddy Maddika, Junjie Chen

Nat Cell Biol. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Nat Cell Biol. 2009 Apr; 11(4): 409–419. Published online 2009 Mar 15. doi: 10.1038/ncb1848

PMCID:: PMC2754075

Abstract Article PDF–4.6M

Select item 777854110.

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway

Lidong Wang, Yonglian Huang, Chenxi Liu, Mingyue Guo, Zhennan Ma, Jingni He, Ailian Wang, Xiaodan Sun, Zhen Liu

J Cancer. 2021; 12(3): 860–873. Published online 2021 Jan 1. doi: 10.7150/jca.48141

PMCID:: PMC7778541

Abstract Article PDF–2.2M

Select item 756785311.

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming

Robert Pedley, Louise E. King, Venkatesh Mallikarjun, Pengbo Wang, Joe Swift, Keith Brennan, Andrew P. Gilmore

Cell Death Dis. 2020 Oct; 11(10): 872. Published online 2020 Oct 16. doi: 10.1038/s41419-020-03091-8

PMCID:: PMC7567853

Abstract Article PDF–2.9M

Select item 851323712.

Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA

Rulan Ma, Kun Zhu, Dawei Yuan, Meijun Gong, Yijun Li, Kang Li, Lei Meng

J Transl Med. 2021; 19: 425. Published online 2021 Oct 13. doi: 10.1186/s12967-021-03100-0

PMCID:: PMC8513237

Abstract Article PDF–4.3M

Select item 983165413.

Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice

Wenjie Zhang, Bowen Shi, Shirui Li, Zenglin Liu, Songhan Li, Shuohui Dong, Yugang Cheng, Jiankang Zhu, Guangyong Zhang, Mingwei Zhong

Front Endocrinol (Lausanne) 2022; 13: 1041027. Published online 2022 Dec 27. doi: 10.3389/fendo.2022.1041027

PMCID:: PMC9831654

Abstract Article PDF–25M

Select item 554619814.

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Joanna K. Lempiäinen, Einari A. Niskanen, Kaisa-Mari Vuoti, Riikka E. Lampinen, Helka Göös, Markku Varjosalo, Jorma J. Palvimo

Mol Cell Proteomics. 2017 Aug; 16(8): 1462–1474. Published online 2017 Jun 13. doi: 10.1074/mcp.M117.067488

PMCID:: PMC5546198

Abstract Article PDF–3.1M

Select item 961539215.

MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer

Pushuai Wen, Huade Wang, Yi Li, Xinyao Sui, Zhijuan Hou, Xiaoyan Guo, Wanying Xue, Dahua Liu, Yu Wang, Jing Gao

Cell Commun Signal. 2022; 20: 170. Published online 2022 Oct 28. doi: 10.1186/s12964-022-00984-3

PMCID:: PMC9615392

Abstract Article PDF–13M

Select item 672167016.

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model

Zoë P. Van Acker, Geert A. Van Raemdonck, Emilie Logie, Sara I. Van Acker, Geert Baggerman, Wim Vanden Berghe, Peter Ponsaerts, Sylvia Dewilde

Cells. 2019 Aug; 8(8): 873. Published online 2019 Aug 11. doi: 10.3390/cells8080873

PMCID:: PMC6721670

Abstract Article PDF–4.1M

Select item 370996617.

HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

Carlos A. Barrero, Prasun K. Datta, Satarupa Sen, Satish Deshmane, Shohreh Amini, Kamel Khalili, Salim Merali

PLoS One. 2013; 8(7): e68376. Published online 2013 Jul 12. doi: 10.1371/journal.pone.0068376

PMCID:: PMC3709966

Abstract Article PDF–1.3M

Select item 803576618.

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer

Bing Li, Zhi-Peng Qi, Dong-Li He, Zhang-Han Chen, Jing-Yi Liu, Meng-Wai Wong, Jia-Wei Zhang, En-Pan Xu, Qiang Shi, Shi-Lun Cai, Di Sun, Li-Qing Yao, Ping-Hong Zhou, Yun-Shi Zhong

J Exp Clin Cancer Res. 2021; 40: 126. Published online 2021 Apr 10. doi: 10.1186/s13046-021-01920-y

PMCID:: PMC8035766

Abstract Article PDF–7.9M

Select item 342832419.

Targeted Ubiquitination and Degradation of G-Protein-Coupled Receptor Kinase 5 by the DDB1-CUL4 Ubiquitin Ligase Complex

Ziyan Wu, Yuejun Chen, Tong Yang, Qinqin Gao, Man Yuan, Lan Ma

PLoS One. 2012; 7(8): e43997. Published online 2012 Aug 27. doi: 10.1371/journal.pone.0043997

PMCID:: PMC3428324

Abstract Article PDF–2.0M

Select item 955026620.

Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition

Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti

Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570

PMCID:: PMC9550266

Abstract Article PDF–2.5M

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