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Select item 86012951.

DDX10 and BYSL as the potential targets of chondrosarcoma and glioma

Xuemin Quan, Changsong Zhao, Zhengrong Gao, Yao Zhang, Rugang Zhao, Jingjing Wang, Qiang Zhang

Medicine (Baltimore) 2021 Nov 19; 100(46): e27669. Published online 2021 Nov 19. doi: 10.1097/MD.0000000000027669

PMCID:: PMC8601295

Abstract Article PDF–1.6M

Select item 82015372.

DDX10 promotes human lung carcinoma proliferation by U3 small nucleolar ribonucleoprotein IMP4

Chunquan Liu, Jizheng Tang, Xinchun Duan, Yanlin Du, Xiaoran Wang, Yong Cui

Thorac Cancer. 2021 Jun; 12(12): 1873–1880. Published online 2021 May 11. doi: 10.1111/1759-7714.13976

PMCID:: PMC8201537

Abstract Article PDF–1.8M

Select item 26820033.

A Novel Small-Subunit Processome Assembly Intermediate That Contains the U3 snoRNP, Nucleolin, RRP5, and DBP4

Amy Jane Turner, Andrew Alexander Knox, José-Luis Prieto, Brian McStay, Nicholas James Watkins

Mol Cell Biol. 2009 Jun; 29(11): 3007–3017. Published online 2009 Mar 30. doi: 10.1128/MCB.00029-09

PMCID:: PMC2682003

Abstract Article PDF–1.4M

Select item 2322664.

The rRNA-processing function of the yeast U14 small nucleolar RNA can be rescued by a conserved RNA helicase-like protein.

W Q Liang, J A Clark, M J Fournier

Mol Cell Biol. 1997 Jul; 17(7): 4124–4132. doi: 10.1128/mcb.17.7.4124

PMCID:: PMC232266

Summary PDF–593K

Select item 79284435.

DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization

Blagovesta Popova, Dan Wang, Christina Pätz, Dagmar Akkermann, Diana F. Lázaro, Dajana Galka, Miriam Kolog Gulko, Markus T. Bohnsack, Wiebke Möbius, Katherine E. Bohnsack, Tiago F. Outeiro, Gerhard H. Braus

PLoS Genet. 2021 Mar; 17(3): e1009407. Published online 2021 Mar 3. doi: 10.1371/journal.pgen.1009407

PMCID:: PMC7928443

Abstract Article PDF–4.7M

Select item 46354926.

Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication – a targeted small interfering RNA library screen using pseudotyped and WT HIV-1

Claire A. Williams, Truus E. M. Abbink, Kuan-Teh Jeang, Andrew M. L. Lever

J Gen Virol. 2015 Jun; 96(Pt 6): 1484–1489. doi: 10.1099/vir.0.000092

PMCID:: PMC4635492

Abstract Article PDF–406K

Select item 59643247.

TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14

Liang Chen, Guixin Zhu, Eleanor M. Johns, Xiaolu Yang

Nat Commun. 2018; 9: 1223. Published online 2018 Mar 26. doi: 10.1038/s41467-018-03499-z

PMCID:: PMC5964324

Abstract Article PDF–3.1M

Select item 57068918.

RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells

Ye Zhang, Xiao-Hong Liao, Hong-Yan Xie, Zhi-Min Shao, Da-Qiang Li

Oncotarget. 2017 Nov 7; 8(55): 94505–94518. Published online 2017 Oct 10. doi: 10.18632/oncotarget.21784

PMCID:: PMC5706891

Abstract Article PDF–3.1M

Select item 27091859.

Identification of Novel SHPS-1-associated Proteins and Their Roles in Regulation of Insulin-like Growth Factor-dependent Responses in Vascular Smooth Muscle Cells

Xinchun Shen, Gang Xi, Yashwanth Radhakrishnan, David R. Clemmons

Mol Cell Proteomics. 2009 Jul; 8(7): 1539–1551. Published online 2009 Mar 18. doi: 10.1074/mcp.M800543-MCP200

PMCID:: PMC2709185

Abstract Article PDF–538K

Select item 669962310.

The human regulatory protein Ki-1/57 is a target of SUMOylation and affects PML nuclear bodies formation

Ângela Saito, Edmarcia E. Souza, Fernanda C. Costa, Gabriela V. Meirelles, Kaliandra A. Gonçalves, Marcos T. Santos, Gustavo C. Bressan, Mark E. McComb, Catherine E. Costello, Stephen A. Whelan, Jörg Kobarg

J Proteome Res. Author manuscript; available in PMC 2019 Aug 19.

Published in final edited form as: J Proteome Res. 2017 Sep 1; 16(9): 3147–3157. Published online 2017 Jul 31. doi: 10.1021/acs.jproteome.7b00001

PMCID:: PMC6699623

Abstract Article PDF–1.0M

Select item 729557611.

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137

Fengwen Zhang, Paul D Bieniasz

eLife. 2020; 9: e55806. Published online 2020 Jun 15. doi: 10.7554/eLife.55806

PMCID:: PMC7295576

Abstract Article PDF–4.3M

Select item 1085081812.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 631799413.

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response

Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan

Cell Rep. Author manuscript; available in PMC 2019 Jan 3.

Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028

PMCID:: PMC6317994

Abstract Article PDF–1.4M

Select item 730617814.

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing

Emily C. Freund, Anne L. Sapiro, Qin Li, Sandra Linder, James J. Moresco, John R. Yates, III, Jin Billy Li

Cell Rep. Author manuscript; available in PMC 2020 Jun 21.

Published in final edited form as: Cell Rep. 2020 May 19; 31(7): 107656. doi: 10.1016/j.celrep.2020.107656

PMCID:: PMC7306178

Abstract Article PDF–1.8M

Select item 827099915.

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

Rui Liu, Lin-Wen Zeng, Rong Gong, Fanen Yuan, Hong-Bing Shu, Shu Li

Nat Commun. 2021; 12: 4227. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24321-3

PMCID:: PMC8270999

Abstract Article PDF–3.8M

Select item 743103016.

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Huettenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J.P. Mathy, Tina Perica, Kala B. Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A. Wankowicz, Markus Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C. O’Neal, Yiming Cai, Jason C.J.Chang, David J. Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu, Hao-Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A Verba, David A. Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, Danica G. Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Sali, Bryan L. Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Brian K. Shoichet, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2020 Oct 30.

Published in final edited form as: Nature. 2020 Jul; 583(7816): 459–468. Published online 2020 Apr 30. doi: 10.1038/s41586-020-2286-9

PMCID:: PMC7431030

Abstract Article PDF–7.7M

Select item 435865917.

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA

Benjamin A Diner, Tuo Li, Todd M Greco, Marni S Crow, John A Fuesler, Jennifer Wang, Ileana M Cristea

Mol Syst Biol. 2015 Feb; 11(2): 787. Published online 2015 Feb 9. doi: 10.15252/msb.20145808

PMCID:: PMC4358659

Abstract Article PDF–3.6M

Select item 456372018.

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression

Benjamin A. Diner, Krystal K. Lum, Aaron Javitt, Ileana M. Cristea

Mol Cell Proteomics. 2015 Sep; 14(9): 2341–2356. Published online 2015 Feb 18. doi: 10.1074/mcp.M114.047068

PMCID:: PMC4563720

Abstract Article PDF–2.8M

Select item 962912119.

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression

Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng

Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651

PMCID:: PMC9629121

Abstract Article PDF–8.1M

Select item 1076495820.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

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