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Select item 104396241.

Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence

Fengzhi Li, Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze, Xiaozhuo Liu, Pawel Kalinski, Dean G. Tang

J Exp Clin Cancer Res. 2023; 42: 213. Published online 2023 Aug 19. doi: 10.1186/s13046-023-02787-x

PMCID:: PMC10439624

Article PDF–3.3M

Select item 103238862.

Hypoxia‐mediated regulation of DDX5 through decreased chromatin accessibility and post‐translational targeting restricts R‐loop accumulation

Katarzyna B. Leszczynska, Monika Dzwigonska, Hala Estephan, Jutta Moehlenbrink, Elizabeth Bowler, Amato J. Giaccia, Jakub Mieczkowski, Bozena Kaminska, Ester M. Hammond

Mol Oncol. 2023 Jul; 17(7): 1173–1191. Published online 2023 Apr 22. doi: 10.1002/1878-0261.13431

PMCID:: PMC10323886

Article PDF–2.6M

Select item 80811633.

The RNA helicase DDX5 promotes viral infection via regulating N⁶-methyladenosine levels on the DHX58 and NFκB transcripts to dampen antiviral innate immunity

Jian Xu, Yunhong Cai, ZhenBang Ma, Bo Jiang, Wenxiao Liu, Jing Cheng, Nannan Guo, Zishu Wang, Joshua E. Sealy, Cuiping Song, Xiaojia Wang, Yongqing Li

PLoS Pathog. 2021 Apr; 17(4): e1009530. Published online 2021 Apr 28. doi: 10.1371/journal.ppat.1009530

PMCID:: PMC8081163

Article PDF–4.6M

Select item 78410594.

Knockdown of DDX5 Inhibits the Proliferation and Tumorigenesis in Esophageal Cancer

Zhenchuan Ma, Jie Feng, Yurui Guo, Ranran Kong, Yuefeng Ma, Liangzhang Sun, Xiaoping Yang, Bin Zhou, Shaomin Li, Wei Zhang, Jiantao Jiang, Jin Zhang, Zhe Qiao, Yao Cheng, Danjie Zha, Shiyuan Liu

Oncol Res. 2017; 25(6): 887–895. Published online 2017 Jul 5. doi: 10.3727/096504016X14817158982636

PMCID:: PMC7841059

Article PDF–2.8M

Select item 75326715.

Restoration of RNA helicase DDX5 suppresses hepatitis B virus (HBV) biosynthesis and Wnt signaling in HBV-related hepatocellular carcinoma

Saravana Kumar Kailasam Mani, Bingyu Yan, Zhibin Cui, Jiazeng Sun, Sagar Utturkar, Adrien Foca, Nadim Fares, David Durantel, Nadia Lanman, Philippe Merle, Majid Kazemian, Ourania Andrisani

Theranostics. 2020; 10(24): 10957–10972. Published online 2020 Sep 1. doi: 10.7150/thno.49629

PMCID:: PMC7532671

Article PDF–3.1M

Select item 71136856.

The DEAD-box RNA helicase DDX5 acts as a positive regulator of Japanese encephalitis virus replication by binding to viral 3′ UTR

Chen Li, Ling-ling Ge, Peng-peng Li, Yue Wang, Ming-xia Sun, Li Huang, Hassan Ishag, Dong-dong Di, Zhi-qiang Shen, Wei-xing Fan, Xiang Mao

Antiviral Res. 2013 Nov; 100(2): 487–499. Published online 2013 Sep 11. doi: 10.1016/j.antiviral.2013.09.002

PMCID:: PMC7113685

Article PDF–2.3M

Select item 69311417.

DDX5 Silencing Suppresses the Migration of Basal cell Carcinoma Cells by Downregulating JAK2/STAT3 Pathway

Zhe Quan, Bei-bei Zhang, Fang Yin, Jiru Du, Yuan-ting Zhi, Jin Xu, Ningjing Song

Technol Cancer Res Treat. 2019; 18: 1533033819892258. Published online 2019 Dec 24. doi: 10.1177/1533033819892258

PMCID:: PMC6931141

Article PDF–2.8M

Select item 63491818.

O‐GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5

Nan Wu, Mingzuo Jiang, Yuying Han, Haiming Liu, Yi Chu, Hao Liu, Jiayi Cao, Qiuqiu Hou, Yu Zhao, Bing Xu, Xin Xie

J Cell Mol Med. 2019 Feb; 23(2): 1354–1362. Published online 2018 Nov 28. doi: 10.1111/jcmm.14038

PMCID:: PMC6349181

Article PDF–733K

Select item 59795479.

DDX5 RNA Helicases: Emerging Roles in Viral Infection

Wenyu Cheng, Guohua Chen, Huaijie Jia, Xiaobing He, Zhizhong Jing

Int J Mol Sci. 2018 Apr; 19(4): 1122. Published online 2018 Apr 9. doi: 10.3390/ijms19041122

PMCID:: PMC5979547

Article PDF–3.2M

Select item 531696110.

DDX5 promotes gastric cancer cell proliferation in vitro and in vivo through mTOR signaling pathway

Cheng Du, Dan-qi Li, Na Li, Li Chen, Shi-sen Li, Yang Yang, Ming-xiao Hou, Man-jiang Xie, Zhen-dong Zheng

Sci Rep. 2017; 7: 42876. Published online 2017 Feb 20. doi: 10.1038/srep42876

PMCID:: PMC5316961

Article PDF–3.0M

Select item 463800211.

DDX5 promotes proliferation and tumorigenesis of non-small-cell lung cancer cells by activating β-catenin signaling pathway

Zhendong Wang, Zhonghua Luo, Lin Zhou, Xiaofei Li, Tao Jiang, Enqing Fu

Cancer Sci. 2015 Oct; 106(10): 1303–1312. Published online 2015 Sep 3. doi: 10.1111/cas.12755

PMCID:: PMC4638002

Article PDF–3.5M

Select item 449177012.

Reduction of toxic RNAs in myotonic dystrophies type 1 and type 2 by the RNA helicase p68/DDX5

Karlie Jones, Christina Wei, Benedikt Schoser, Giovanni Meola, Nikolai Timchenko, Lubov Timchenko

Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26): 8041–8045. Published online 2015 Jun 15. doi: 10.1073/pnas.1422273112

PMCID:: PMC4491770

Article PDF–1.0M

Select item 410007013.

Acquired Dependence Of Acute Myeloid Leukemia On The DEAD-BOX RNA Helicase DDX5

Anthony Mazurek, Youngkyu Park, Cornelius Miething, John E. Wilkinson, Jesse Gillis, Scott W. Lowe, Christopher R. Vakoc, Bruce Stillman

Cell Rep. Author manuscript; available in PMC 2014 Jul 16.

Published in final edited form as: Cell Rep. 2014 Jun 26; 7(6): 1887–1899. Published online 2014 Jun 5. doi: 10.1016/j.celrep.2014.05.019

PMCID:: PMC4100070

Article PDF–2.5M

Select item 344054614.

DDX5 Regulates DNA Replication And Is Required For Cell Proliferation In A Subset Of Breast Cancer Cells

Anthony Mazurek, Weijun Luo, Alexander Krasnitz, James Hicks, R. Scott Powers, Bruce Stillman

Cancer Discov. Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Cancer Discov. 2012 Sep; 2(9): 812–825. Published online 2012 Jun 29. doi: 10.1158/2159-8290.CD-12-0116

PMCID:: PMC3440546

Article PDF–2.3M

Select item 342420815.

p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50

Rui Wang, Zhuomin Jiao, Ruiyan Li, Hui Yue, Lijie Chen

Neuro Oncol. 2012 Sep; 14(9): 1116–1124. Published online 2012 Jul 18. doi: 10.1093/neuonc/nos131

PMCID:: PMC3424208

Article PDF–398K

Select item 332633016.

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

François-Xavier Laurent, Alain Sureau, Arnaud F. Klein, François Trouslard, Erwan Gasnier, Denis Furling, Joëlle Marie

Nucleic Acids Res. 2012 Apr; 40(7): 3159–3171. Published online 2011 Dec 9. doi: 10.1093/nar/gkr1228

PMCID:: PMC3326330

Article PDF–7.2M

Select item 281569017.

Expression, purification and preliminary crystallographic analysis of recombinant human DEAD-box polypeptide 5

Yook-Wah Choi, Sujit Dutta, Burtram C. Fielding, Yee-Joo Tan

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1; 66(Pt 2): 192–194. Published online 2010 Jan 28. doi: 10.1107/S1744309109052956

PMCID:: PMC2815690

Article PDF–189K

Select item 249155318.

P68 RNA Helicase (DDX5) Alters Activity of Cis- and Trans-Acting Factors of the Alternative Splicing of H-Ras

Maria Camats, Sonia Guil, Mariette Kokolo, Montse Bach-Elias

PLoS One. 2008; 3(8): e2926. Published online 2008 Aug 13. doi: 10.1371/journal.pone.0002926

PMCID:: PMC2491553

Article PDF–881K

Select item 189497519.

Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme

Li-Jen Su, Ching-Wei Chang, Yu-Chung Wu, Kuang-Chi Chen, Chien-Ju Lin, Shu-Ching Liang, Chi-Hung Lin, Jacqueline Whang-Peng, Shih-Lan Hsu, Chen-Hsin Chen, Chi-Ying F Huang

BMC Genomics. 2007; 8: 140. Published online 2007 Jun 1. doi: 10.1186/1471-2164-8-140