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Select item 109123461.

Function of KvLQT1 potassium channels in a mouse model of bleomycin-induced acute lung injury

Mélissa Aubin Vega, Alban Girault, Émilie Meunier, Jasmine Chebli, Anik Privé, Annette Robichaud, Damien Adam, Emmanuelle Brochiero

Front Physiol. 2024; 15: 1345488. Published online 2024 Feb 20. doi: 10.3389/fphys.2024.1345488

PMCID:: PMC10912346

Abstract Article PDF–4.0M

Select item 108284892.

Coronary and carotid artery dysfunction and K_V7 overexpression in a mouse model of Hutchinson-Gilford progeria syndrome

Álvaro Macías, Rosa M. Nevado, Cristina González-Gómez, Pilar Gonzalo, María Jesús Andrés-Manzano, Beatriz Dorado, Ignacio Benedicto, Vicente Andrés

GeroScience. 2024 Feb; 46(1): 867–884. Published online 2023 May 26. doi: 10.1007/s11357-023-00808-3

PMCID:: PMC10828489

Abstract Article PDF–6.1M

Select item 81929013.

Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

Anniek F. Lubberding, Jinyi Zhang, Morten Lundh, Thomas Svava Nielsen, Mathilde S. Søndergaard, Maria Villadsen, Emil Z. Skovhøj, Geke A. Boer, Jakob B. Hansen, Morten B. Thomsen, Jonas T. Treebak, Jens J. Holst, Jørgen K. Kanters, Thomas Mandrup-Poulsen, Thomas Jespersen, Brice Emanuelli, Signe S. Torekov

Sci Rep. 2021; 11: 12253. Published online 2021 Jun 10. doi: 10.1038/s41598-021-90452-8

PMCID:: PMC8192901

Abstract Article PDF–2.1M

Select item 66793904.

Different functional roles for K⁺ channel subtypes in regulating small intestinal glucose and ion transport

Chao Du, Siyuan Chen, Hanxing Wan, Lihong Chen, Lingyu Li, Hong Guo, Biguang Tuo, Hui Dong

Biol Open. 2019 Jul 15; 8(7): bio042200. Published online 2019 Jun 26. doi: 10.1242/bio.042200

PMCID:: PMC6679390

Abstract Article PDF–6.2M

Select item 64835095.

KCNQ/M-channels regulate mouse vagal bronchopulmonary C-fiber excitability and cough sensitivity

Hui Sun, An-Hsuan Lin, Fei Ru, Mayur J. Patil, Sonya Meeker, Lu-Yuan Lee, Bradley J. Undem

JCI Insight. 2019 Mar 7; 4(5): e124467. Published online 2019 Mar 7. doi: 10.1172/jci.insight.124467

PMCID:: PMC6483509

Abstract Article PDF–1.6M

Select item 45513456.

Virally mediated Kcnq1 gene replacement therapy in the immature scala media restores hearing in a mouse model of human Jervell and Lange-Nielsen deafness syndrome

Qing Chang, Jianjun Wang, Qi Li, Yeunjung Kim, Binfei Zhou, Yunfeng Wang, Huawei Li, Xi Lin

EMBO Mol Med. 2015 Aug; 7(8): 1077–1086. Published online 2015 Jun 17. doi: 10.15252/emmm.201404929

PMCID:: PMC4551345

Abstract Article PDF–2.8M

Select item 36444807.

Hypothyroidism of gene-targeted mice lacking Kcnq1

Henning Fröhlich, Krishna M. Boini, Guiscard Seebohm, Nathalie Strutz-Seebohm, Oana N. Ureche, Michael Föller, Melanie Eichenmüller, Ekaterina Shumilina, Ganesh Pathare, Anurag Kumar Singh, Ursula Seidler, Karl E. Pfeifer, Florian Lang

Pflugers Arch. Author manuscript; available in PMC 2013 May 5.

Published in final edited form as: Pflugers Arch. 2011 Jan; 461(1): 45–52. Published online 2010 Oct 27. doi: 10.1007/s00424-010-0890-5

PMCID:: PMC3644480

Abstract Article PDF–1.3M

Select item 26927908.

Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1

Krishna M. Boini, Dirk Graf, Anita M. Hennige, Saisudha Koka, Daniela S. Kempe, Kan Wang, Teresa F. Ackermann, Michael Föller, Volker Vallon, Karl Pfeifer, Erwin Schleicher, Susanne Ullrich, Hans-Ulrich Häring, Dieter Häussinger, Florian Lang

Am J Physiol Regul Integr Comp Physiol. 2009 Jun; 296(6): R1695–R1701. Published online 2009 Apr 15. doi: 10.1152/ajpregu.90839.2008

PMCID:: PMC2692790

Abstract Article

Select item 26892229.

Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus

Siemon H Ng, Rose Madeira, Emil D Parvanov, Lorin M Petros, Petko M Petkov, Kenneth Paigen

BMC Mol Biol. 2009; 10: 43. Published online 2009 May 13. doi: 10.1186/1471-2199-10-43

PMCID:: PMC2689222

Abstract Article PDF–408K

Select item 202568610.

Kcnq1 Contributes to an Adrenergic-Sensitive Steady-State K⁺ Current in Mouse Heart

Bjorn C. Knollmann, Syevda Sirenko, Qi Rong, Alexander N. Katchman, Mathew Casimiro, Karl Pfeifer, Steven N. Ebert

Biochem Biophys Res Commun. Author manuscript; available in PMC 2008 Aug 17.

Published in final edited form as: Biochem Biophys Res Commun. 2007 Aug 17; 360(1): 212–218. Published online 2007 Jun 15. doi: 10.1016/j.bbrc.2007.06.038

PMCID:: PMC2025686

Abstract Article PDF–1019K

Select item 3017111.

Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange– Nielsen Syndrome

Mathew C. Casimiro, Björn C. Knollmann, Steven N. Ebert, Jay C. Vary, Jr., Anne E. Greene, Michael R. Franz, Alexander Grinberg, Sing Ping Huang, Karl Pfeifer

Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5): 2526–2531. doi: 10.1073/pnas.041398998

PMCID:: PMC30171

Abstract Article PDF–376K

Select item 670446412.

The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury

Leng Zhou, Clemens Köhncke, Zhaoyang Hu, Torsten K. Roepke, Geoffrey W. Abbott

FASEB J. 2019 Sep; 33(9): 9762–9774. Published online 2019 Jun 4. doi: 10.1096/fj.201802519R

PMCID:: PMC6704464

Abstract Article

Select item 668750113.

Transcription alterations of KCNQ1 associated with imprinted methylation defects in the Beckwith–Wiedemann locus

Federica Maria Valente, Angela Sparago, Andrea Freschi, Katherine Hill-Harfe, Saskia M. Maas, Suzanna Gerarda Maria Frints, Marielle Alders, Laura Pignata, Monica Franzese, Claudia Angelini, Diana Carli, Alessandro Mussa, Andrea Gazzin, Fulvio Gabbarini, Basilia Acurzio, Giovanni Battista Ferrero, Jet Bliek, Charles A. Williams, Andrea Riccio, Flavia Cerrato

Genet Med. 2019; 21(8): 1808–1820. Published online 2019 Jan 12. doi: 10.1038/s41436-018-0416-7

PMCID:: PMC6687501

Abstract Article PDF–2.6M

Select item 580341014.

Pharmacogenetics of KCNQ channel activation in two potassium channelopathy mouse models of epilepsy

Stephanie L. Vanhoof-Villalba, Nicole M. Gautier, Vikas Mishra, Edward Glasscock

Epilepsia. Author manuscript; available in PMC 2019 Feb 1.

Published in final edited form as: Epilepsia. 2018 Feb; 59(2): 358–368. Published online 2017 Dec 19. doi: 10.1111/epi.13978

PMCID:: PMC5803410

Abstract Article PDF–885K

Select item 499665215.

Protein arginine methylation facilitates KCNQ channel-PIP₂ interaction leading to seizure suppression

Hyun-Ji Kim, Myong-Ho Jeong, Kyung-Ran Kim, Chang-Yun Jung, Seul-Yi Lee, Hanna Kim, Jewoo Koh, Tuan Anh Vuong, Seungmoon Jung, Hyunwoo Yang, Su-Kyung Park, Dahee Choi, Sung Hun Kim, KyeongJin Kang, Jong-Woo Sohn, Joo Min Park, Daejong Jeon, Seung-Hoi Koo, Won-Kyung Ho, Jong-Sun Kang, Seong-Tae Kim, Hana Cho

eLife. 2016; 5: e17159. Published online 2016 Jul 28. doi: 10.7554/eLife.17159

PMCID:: PMC4996652

Abstract Article PDF–3.7M

Select item 388278716.

Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus

He Zhang, Michael J. Zeitz, Hong Wang, Beibei Niu, Shengfang Ge, Wei Li, Jiuwei Cui, Guanjun Wang, Guanxiang Qian, Michael J. Higgins, Xianqun Fan, Andrew R. Hoffman, Ji-Fan Hu

J Cell Biol. 2014 Jan 6; 204(1): 61–75. doi: 10.1083/jcb.201304152

PMCID:: PMC3882787

Abstract Article PDF–3.6M

Select item 340527817.

The KCNQ1-KCNE2 K⁺ channel is required for adequate thyroid I⁻ uptake

Kerry Purtell, Monika Paroder-Belenitsky, Andrea Reyna-Neyra, Juan P. Nicola, Wade Koba, Eugene Fine, Nancy Carrasco, Geoffrey W. Abbott

FASEB J. 2012 Aug; 26(8): 3252–3259. doi: 10.1096/fj.12-206110

PMCID:: PMC3405278

Abstract Article

Select item 295175418.

Arrhythmia in Heart and Brain: KCNQ1 Mutations Link Epilepsy and Sudden Unexplained Death

A. M. Goldman, E. Glasscock, J. Yoo, T. T. Chen, T. L. Klassen, J. L. Noebels

Sci Transl Med. Author manuscript; available in PMC 2010 Oct 8.

Published in final edited form as: Sci Transl Med. 2009 Oct 14; 1(2): 2ra6. doi: 10.1126/scitranslmed.3000289

PMCID:: PMC2951754

Abstract Article PDF–3.1M

Select item 284416619.

Disruption of the K⁺ Channel β-Subunit KCNE3 Reveals an Important Role in Intestinal and Tracheal Cl⁻ Transport

Patricia Preston, Lena Wartosch, Dorothee Günzel, Michael Fromm, Patthara Kongsuphol, Jiraporn Ousingsawat, Karl Kunzelmann, Jacques Barhanin, Richard Warth, Thomas J. Jentsch

J Biol Chem. 2010 Mar 5; 285(10): 7165–7175. Published online 2010 Jan 5. doi: 10.1074/jbc.M109.047829

PMCID:: PMC2844166

Abstract Article PDF–3.3M

Select item 274662220.

KCNQ1 is the luminal K⁺ recycling channel during stimulation of gastric acid secretion

Penghong Song, Stephanie Groos, Brigitte Riederer, Zhe Feng, Anja Krabbenhöft, Adam Smolka, Ursula Seidler

J Physiol. 2009 Aug 1; 587(Pt 15): 3955–3965. Published online 2009 Jun 2. doi: 10.1113/jphysiol.2009.173302

PMCID:: PMC2746622

Abstract Article PDF–671K

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PMC Links for Gene (Select 16535) (90)
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The functional small RNA interactome reveals targets for the vancomycin-responsi...
The functional small RNA interactome reveals targets for the vancomycin-responsive sRNA RsaOI in vancomycin tolerant Staphylococcus aureus.
The functional small RNA interactome reveals targets for the vancomycin-responsive sRNA RsaOI in vancomycin tolerant Staphylococcus aureus.

BioProject
nssv453974 (0)
PopSet
potassium voltage-gated channel subfamily KQT member 1 isoform X5 [Mus musculus]
potassium voltage-gated channel subfamily KQT member 1 isoform X5 [Mus musculus]
gi|1720421032|ref|XP_006508554.3|

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nssv1455858 AND (alive[prop]) (0)
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