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Select item 103754641.

A humanized equation M1

integrin knockin mouse reveals localized intra- and extravascular neutrophil integrin activation in vivo

Lai Wen, Alex Marki, Zhihao Wang, Marco Orecchioni, Jeffrey Makings, Monica Billitti, Erpei Wang, Sujit S.A. Suthahar, Kenneth Kim, William B. Kiosses, Zbigniew Mikulski, Klaus Ley

Cell Rep. Author manuscript; available in PMC 2023 Jul 28.

Published in final edited form as: Cell Rep. 2022 May 31; 39(9): 110876. doi: 10.1016/j.celrep.2022.110876

PMCID:: PMC10375464

Abstract Article PDF–2.6M

Select item 100945782.

The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells—Lessons Learned from Different Transgenic Mouse Models

Tanja Klaus, Alicia Wilson, Michael Fichter, Matthias Bros, Tobias Bopp, Stephan Grabbe

Int J Mol Sci. 2023 Apr; 24(7): 6331. Published online 2023 Mar 28. doi: 10.3390/ijms24076331

PMCID:: PMC10094578

Abstract Article PDF–1.0M

Select item 95743673.

CD18 controls the development and activation of monocyte-to-macrophage axis during chronic schistosomiasis

Camila O. S. Souza, Jefferson Elias-Oliveira, Marcella R. Pastore, Caroline Fontanari, Vanessa F. Rodrigues, Vanderlei Rodriguez, Luiz G. Gardinassi, Lúcia H. Faccioli

Front Immunol. 2022; 13: 929552. Published online 2022 Oct 3. doi: 10.3389/fimmu.2022.929552

PMCID:: PMC9574367

Abstract Article PDF–4.5M

Select item 93229994.

β2 Integrins on Dendritic Cells Modulate Cytokine Signaling and Inflammation-Associated Gene Expression, and Are Required for Induction of Autoimmune Encephalomyelitis

Monika Bednarczyk, Vanessa Bolduan, Maximilian Haist, Henner Stege, Christoph Hieber, Lisa Johann, Carsten Schelmbauer, Michaela Blanfeld, Khalad Karram, Jenny Schunke, Tanja Klaus, Ingrid Tubbe, Evelyn Montermann, Nadine Röhrig, Maike Hartmann, Jana Schlosser, Tobias Bopp, Björn E Clausen, Ari Waisman, Matthias Bros, Stephan Grabbe

Cells. 2022 Jul; 11(14): 2188. Published online 2022 Jul 13. doi: 10.3390/cells11142188

PMCID:: PMC9322999

Abstract Article PDF–3.7M

Select item 83299265.

Platelet and Erythrocyte Extravasation across Inflamed Corneal Venules Depend on CD18, Neutrophils, and Mast Cell Degranulation

Angie De La Cruz, Aubrey Hargrave, Sri Magadi, Justin A. Courson, Paul T. Landry, Wanyu Zhang, Fong W. Lam, Monica A. Bray, C. Wayne Smith, Alan R. Burns, Rolando E. Rumbaut

Int J Mol Sci. 2021 Jul; 22(14): 7360. Published online 2021 Jul 8. doi: 10.3390/ijms22147360

PMCID:: PMC8329926

Abstract Article PDF–5.0M

Select item 77890146.

The role of β₂ integrin in dendritic cell migration during infection

Tarfa Altorki, Werner Muller, Andrew Brass, Sheena Cruickshank

BMC Immunol. 2021; 22: 2. Published online 2021 Jan 6. doi: 10.1186/s12865-020-00394-5

PMCID:: PMC7789014

Abstract Article PDF–16M

Select item 77144427.

Role of LFA-1 integrin in the control of a lymphocytic choriomeningitis virus (LCMV) infection

Mario Perro, Matteo Iannacone, Ulrich H. von Andrian, Antonio Peixoto

Virulence. 2020; 11(1): 1640–1655. Published online 2020 Nov 29. doi: 10.1080/21505594.2020.1845506

PMCID:: PMC7714442

Abstract Article PDF–7.7M

Select item 76148638.

Differential nanoscale organisation of LFA-1 modulates T cell migration

Michael J. Shannon, Judith Pineau, Juliette Griffié, Jesse Aaron, Tamlyn Peel, David J. Williamson, Rose Zamoyska, Andrew P. Cope, Georgina H. Cornish, Dylan M. Owen

J Cell Sci. Author manuscript; available in PMC 2023 Aug 2.

Published in final edited form as: J Cell Sci. 2019 Oct 16; 133(5): jcs232991. Published online 2019 Oct 16. doi: 10.1242/jcs.232991

PMCID:: PMC7614863

Abstract Article PDF–2.8M

Select item 75025899.

LFA-1 signals to promote actin polymerization and upstream migration in T cells

Nathan H. Roy, Sarah Hyun Ji Kim, Alexander Buffone, Jr, Daniel Blumenthal, Bonnie Huang, Sangya Agarwal, Pamela L. Schwartzberg, Daniel A. Hammer, Janis K. Burkhardt

J Cell Sci. 2020 Sep 1; 133(17): jcs248328. Published online 2020 Sep 9. doi: 10.1242/jcs.248328

PMCID:: PMC7502589

Abstract Article

Select item 748678110.

β2 Integrins differentially regulate γδ T cell subset thymic development and peripheral maintenance

Claire L. McIntyre, Leticia Monin, Jesse C. Rop, Thomas D. Otto, Carl S. Goodyear, Adrian C. Hayday, Vicky L. Morrison

Proc Natl Acad Sci U S A. 2020 Sep 8; 117(36): 22367–22377. Published online 2020 Aug 26. doi: 10.1073/pnas.1921930117

PMCID:: PMC7486781

Abstract Article PDF–1.6M

Select item 684978111.

The Impact of Integrin β2 on Granulocyte/Macrophage Progenitor Proliferation

Li‐Jie Zhang, Cen Yan, Sarah Schouteden, Xiao‐Juan Ma, Dong Zhao, Thorsten Peters, Catherine M. Verfaillie, Ying‐Mei Feng

Stem Cells. 2019 Mar; 37(3): 430–440. Published online 2019 Feb 7. doi: 10.1002/stem.2961

PMCID:: PMC6849781

Abstract Article PDF–1.2M

Select item 660800812.

Leukocyte‐borne α(1,3)‐fucose is a negative regulator of β₂‐integrin‐dependent recruitment in lung inflammation

Alexander Buffone, Jr., Mehrab Nasirikenari, Charles T. Manhardt, Amit Lugade, Paul N. Bogner, Robert Sackstein, Yasmin Thanavala, Sriram Neelamegham, Joseph T. Y. Lau

J Leukoc Biol. 2017 Feb; 101(2): 459–470. Published online 2016 Aug 26. doi: 10.1189/jlb.3A0516-215RR

PMCID:: PMC6608008

Abstract Article

Select item 612727513.

CD18 Regulates Monocyte Hematopoiesis and Promotes Resistance to Experimental Schistosomiasis

Camila O. S. Souza, Milena S. Espíndola, Caroline Fontanari, Morgana K. B. Prado, Fabiani G. Frantz, Vanderlei Rodrigues, Luiz G. Gardinassi, Lúcia H. Faccioli

Front Immunol. 2018; 9: 1970. Published online 2018 Aug 31. doi: 10.3389/fimmu.2018.01970

PMCID:: PMC6127275

Abstract Article PDF–4.5M

Select item 571800614.

Decreased expression of the β₂ integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

Aitor Benedicto, Joana Marquez, Alba Herrero, Elvira Olaso, Elzbieta Kolaczkowska, Beatriz Arteta

BMC Cancer. 2017; 17: 827. Published online 2017 Dec 6. doi: 10.1186/s12885-017-3823-2

PMCID:: PMC5718006

Abstract Article PDF–2.0M

Select item 558492615.

CD18 deficiency improves liver injury in the MCD model of steatohepatitis

Andrew A. Pierce, Caroline C. Duwaerts, Kevin Siao, Aras N. Mattis, Amanda Goodsell, Jody L. Baron, Jacquelyn J. Maher

PLoS One. 2017; 12(9): e0183912. Published online 2017 Sep 5. doi: 10.1371/journal.pone.0183912

PMCID:: PMC5584926

Abstract Article PDF–14M

Select item 458318716.

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

Paul J. Meakin, Vicky L. Morrison, Claire C. Sneddon, Terhi Savinko, Liisa Uotila, Susan M. Jalicy, Jennie L. Gabriel, Li Kang, Michael L. J. Ashford, Susanna C. Fagerholm

PLoS One. 2015; 10(9): e0138872. Published online 2015 Sep 25. doi: 10.1371/journal.pone.0138872

PMCID:: PMC4583187

Abstract Article PDF–2.7M

Select item 440403417.

T Cell-Extrinsic CD18 Attenuates Antigen-Dependent CD4⁺ T cell Activation In Vivo

Xingxin Wu, Amit Lahiri, Ritu Sarin, Clara Abraham

J Immunol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: J Immunol. 2015 May 1; 194(9): 4122–4129. Published online 2015 Mar 23. doi: 10.4049/jimmunol.1401328

PMCID:: PMC4404034

Abstract Article PDF–1.6M

Select item 425860618.

Loss of beta2-integrin-mediated cytoskeletal linkage reprograms dendritic cells to a mature migratory phenotype

Vicky Louise Morrison, Martyn John James, Katarzyna Grzes, Peter Cook, David Gavin Glass, Terhi Savinko, Hwee San Lek, Christian Gawden-Bone, Colin Watts, Owain Richard Millington, Andrew Scott MacDonald, Susanna Carola Fagerholm

Nat Commun. Author manuscript; available in PMC 2015 Apr 28.

Published in final edited form as: Nat Commun. 2014; 5: 5359. Published online 2014 Oct 28. doi: 10.1038/ncomms6359