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Select item 108838381.

Iron/ROS/Itga3 mediated accelerated depletion of hippocampal neural stem cell pool contributes to cognitive impairment after hemorrhagic stroke

Xuyang Zhang, Huanhuan Li, Haomiao Wang, Qian Zhang, Xueyun Deng, Shuixian Zhang, Long Wang, Chao Guo, Fengchun Zhao, Yi Yin, Tengyuan Zhou, Jun Zhong, Hui Feng, Wei Chen, Jun Zhang, Hua Feng, Rong Hu

Redox Biol. 2024 May; 71: 103086. Published online 2024 Feb 13. doi: 10.1016/j.redox.2024.103086

PMCID:: PMC10883838

Abstract Article PDF–13M

Select item 76807212.

Integrin α3β1 on tumor keratinocytes is essential to maintain tumor growth and promotes a tumor-supportive keratinocyte secretome.

Whitney M. Longmate, Scott Varney, Derek Power, Rakshitha Pandulal Miskin, Karl E. Anderson, Lori DeFreest, Livingston Van De Water, C. Michael DiPersio

J Invest Dermatol. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: J Invest Dermatol. 2021 Jan; 141(1): 142–151.e6. Published online 2020 May 23. doi: 10.1016/j.jid.2020.05.080

PMCID:: PMC7680721

Abstract Article PDF–2.2M

Select item 71719223.

Keratinocyte integrin α3β1 promotes secretion of IL-1α to effect paracrine regulation of fibroblast gene expression and differentiation

Rui Zheng, Whitney M. Longmate, Lori DeFreest, Scott Varney, Lei Wu, C. Michael DiPersio, Livingston Van De Water

J Invest Dermatol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: J Invest Dermatol. 2019 Sep; 139(9): 2029–2038.e3. Published online 2019 Mar 13. doi: 10.1016/j.jid.2019.02.025

PMCID:: PMC7171922

Abstract Article PDF–1.9M

Select item 39470214.

Integrin α3β1 Can Function to Promote Spontaneous Metastasis and Lung Colonization of Invasive Breast Carcinoma

Bo Zhou, Katherine N. Gibson-Corley, Mary E. Herndon, Yihan Sun, Elisabeth Gustafson-Wagner, Melissa Teoh-Fitzgerald, Frederick E. Domann, Michael D. Henry, Christopher S. Stipp

Mol Cancer Res. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Mol Cancer Res. 2014 Jan; 12(1): 143–154. Published online 2013 Sep 3. doi: 10.1158/1541-7786.MCR-13-0184

PMCID:: PMC3947021

Abstract Article PDF–3.5M

Select item 36459985.

Adhesion Proteins - An Impact on Skeletal Myoblast Differentiation

Marta Przewoźniak, Iwona Czaplicka, Areta M. Czerwińska, Agnieszka Markowska-Zagrajek, Jerzy Moraczewski, Władysława Stremińska, Katarzyna Jańczyk-Ilach, Maria A. Ciemerych, Edyta Brzoska

PLoS One. 2013; 8(5): e61760. Published online 2013 May 6. doi: 10.1371/journal.pone.0061760

PMCID:: PMC3645998

Abstract Article PDF–10M

Select item 35335486.

Gain of glycosylation in integrin α3 causes lung disease and nephrotic syndrome

Nayia Nicolaou, Coert Margadant, Sietske H. Kevelam, Marc R. Lilien, Michiel J.S. Oosterveld, Maaike Kreft, Albertien M. van Eerde, Rolph Pfundt, Paulien A. Terhal, Bert van der Zwaag, Peter G.J. Nikkels, Norman Sachs, Roel Goldschmeding, Nine V.A.M. Knoers, Kirsten Y. Renkema, Arnoud Sonnenberg

J Clin Invest. 2012 Dec 3; 122(12): 4375–4387. Published online 2012 Nov 1. doi: 10.1172/JCI64100

PMCID:: PMC3533548

Abstract Article PDF–5.2M

Select item 29289837.

Endothelial α3β1-Integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF

Rita Graça da Silva, Bernardo Tavora, Stephen D. Robinson, Louise E. Reynolds, Charles Szekeres, John Lamar, Sílvia Batista, Vassiliki Kostourou, Mitchel A. Germain, Andrew R. Reynolds, Dylan T. Jones, Alan R. Watson, Janet L. Jones, Adrian Harris, Ian R. Hart, M. Luisa Iruela-Arispe, C. Michael DiPersio, Jordan A. Kreidberg, Kairbaan M. Hodivala-Dilke

Am J Pathol. 2010 Sep; 177(3): 1534–1548. doi: 10.2353/ajpath.2010.100043

PMCID:: PMC2928983

Abstract Article PDF–1.1M

Select item 21493498.

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes

Kairbaan M. Hodivala-Dilke, C. Michael DiPersio, Jordan A. Kreidberg, Richard O. Hynes

J Cell Biol. 1998 Sep 7; 142(5): 1357–1369. doi: 10.1083/jcb.142.5.1357

PMCID:: PMC2149349

Abstract Article PDF–1.3M

Select item 19940829.

α3-Integrins are required for hippocampal long-term potentiation and working memory

Chi-Shing Chan, Jonathan M. Levenson, Partha S. Mukhopadhyay, Lin Zong, Allan Bradley, J. David Sweatt, Ronald L. Davis

Learn Mem. 2007 Sep; 14(9): 606–615. doi: 10.1101/lm.648607

PMCID:: PMC1994082

Abstract Article PDF–746K

Select item 1082172010.

Integrin α3 promotes Th17 cell polarization and extravasation during autoimmune neuroinflammation.

Eunchong Park, William E. Barclay, Alejandro Barrera, Tzu-Chieh Liao, Harmony R. Salzler, Timothy E. Reddy, Mari L. Shinohara, Maria Ciofani

Sci Immunol. Author manuscript; available in PMC 2024 Jan 27.

Published in final edited form as: Sci Immunol. 2023 Oct 20; 8(88): eadg7597. Published online 2023 Oct 13. doi: 10.1126/sciimmunol.adg7597

PMCID:: PMC10821720

Abstract Article PDF–3.2M

Select item 1074812811.

The Role of α3β1 Integrin Modulation on Fabry Disease Podocyte Injury and Kidney Impairment

Bruna Bosquetti, Aline Aparecida Santana, Paulo Cézar Gregório, Regiane Stafim da Cunha, Guilherme Miniskiskosky, Julia Budag, Célia Regina Cavichiolo Franco, Edneia Amancio de Souza Ramos, Fellype Carvalho Barreto, Andréa Emilia Marques Stinghen

Toxins (Basel) 2023 Dec; 15(12): 700. Published online 2023 Dec 14. doi: 10.3390/toxins15120700

PMCID:: PMC10748128

Abstract Article PDF–12M

Select item 652536212.

Absence of integrin α3β1 promotes the progression of HER2-driven breast cancer in vivo

Veronika Ramovs, Pablo Secades, Ji-Ying Song, Bram Thijssen, Maaike Kreft, Arnoud Sonnenberg

Breast Cancer Res. 2019; 21: 63. Published online 2019 May 17. doi: 10.1186/s13058-019-1146-8

PMCID:: PMC6525362

Abstract Article PDF–6.4M

Select item 639908013.

The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth

Eugenia M. Yazlovitskaya, Olga Viquez, Tianxiang Tu, Adele De Arcangelis, Elisabeth Georges-Labouesse, Arnoud Sonnenberg, Ambra Pozzi, Roy Zent

Matrix Biol. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Matrix Biol. 2019 Apr; 77: 101–116. Published online 2018 Sep 4. doi: 10.1016/j.matbio.2018.08.010

PMCID:: PMC6399080

Abstract Article PDF–2.8M

Select item 543689214.

Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump

Toke Jost Isaksen, Lieke Kros, Natascia Vedovato, Thomas Hellesøe Holm, Ariel Vitenzon, David C. Gadsby, Kamran Khodakhah, Karin Lykke-Hartmann

PLoS Genet. 2017 May; 13(5): e1006763. Published online 2017 May 4. doi: 10.1371/journal.pgen.1006763

PMCID:: PMC5436892

Abstract Article PDF–6.5M

Select item 425690515.

Sepsis lethality via exacerbated tissue infiltration and TLR-induced cytokine production by neutrophils is integrin α₃β₁-dependent

Yelena V. Lerman, Kihong Lim, Young-Min Hyun, Kathleen L. Falkner, Hongmei Yang, Anthony P. Pietropaoli, Arnoud Sonnenberg, Pranita P. Sarangi, Minsoo Kim

Blood. 2014 Dec 4; 124(24): 3515–3523. Prepublished online 2014 Oct 2. doi: 10.1182/blood-2014-01-552943

PMCID:: PMC4256905

Abstract Article

Select item 353562516.

Loss of integrin α3 prevents skin tumor formation by promoting epidermal turnover and depletion of slow-cycling cells

Norman Sachs, Pablo Secades, Laura van Hulst, Maaike Kreft, Ji-Ying Song, Arnoud Sonnenberg

Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52): 21468–21473. Published online 2012 Dec 10. doi: 10.1073/pnas.1204614110

PMCID:: PMC3535625

Abstract Article PDF–1.3M

Select item 309848517.

Control of mammary myoepithelial cell contractile function by α3β1 integrin signalling

Karine Raymond, Stéphanie Cagnet, Maaike Kreft, Hans Janssen, Arnoud Sonnenberg, Marina A Glukhova

EMBO J. 2011 May 18; 30(10): 1896–1906. Published online 2011 Apr 12. doi: 10.1038/emboj.2011.113

PMCID:: PMC3098485

Abstract Article PDF–1.5M

Select item 306412918.

Dystroglycan does not contribute significantly to kidney development or function, in health or after injury

George Jarad, Jeffrey W. Pippin, Stuart J. Shankland, Jordan A. Kreidberg, Jeffrey H. Miner

Am J Physiol Renal Physiol. 2011 Mar; 300(3): F811–F820. Published online 2011 Jan 5. doi: 10.1152/ajprenal.00725.2010

PMCID:: PMC3064129

Abstract Article

Select item 278277519.

An immortalization-dependent switch in integrin function upregulates MMP-9 to enhance tumor cell invasion

John M. Lamar, Kevin M. Pumiglia, C. Michael DiPersio

Cancer Res. Author manuscript; available in PMC 2009 Nov 25.

Published in final edited form as: Cancer Res. 2008 Sep 15; 68(18): 7371–7379. doi: 10.1158/0008-5472.CAN-08-1080

PMCID:: PMC2782775

Abstract Article PDF–888K

Select item 221573020.

α3β1 integrin–controlled Smad7 regulates reepithelialization during wound healing in mice

Louise E. Reynolds, Francesco J. Conti, Rita Silva, Stephen D. Robinson, Vandana Iyer, Rob Rudling, Barbara Cross, Emma Nye, Ian R. Hart, C. Michael DiPersio, Kairbaan M. Hodivala-Dilke

J Clin Invest. 2008 Mar 3; 118(3): 965–974. Published online 2008 Feb 1. doi: 10.1172/JCI33538