PMC Links for Gene (Select 161198) - PMC

Select item 91185341.

CLEC14A was up-regulated in hepatocellular carcinoma and may function as a potential diagnostic biomarker

Lang Yan, Xiang Li, Yunfeng Yuan

Clinics (Sao Paulo) 2022 Jan-Dec; 77: 100029. Published online 2022 May 14. doi: 10.1016/j.clinsp.2022.100029

PMCID:: PMC9118534

Article PDF–853K

Select item 75783012.

An evaluation of the tumour endothelial marker CLEC14A as a therapeutic target in solid tumours

Joseph Robinson, Katharine Whitworth, Elizabeth Jinks, Zsuzsanna Nagy, Roy Bicknell, Steven P Lee

J Pathol Clin Res. 2020 Oct; 6(4): 308–319. Published online 2020 Jul 21. doi: 10.1002/cjp2.176

PMCID:: PMC7578301

Article PDF–7.4M

Select item 70499583.

Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin-binding protein

Daniel R. Sandoval, Alejandro Gomez Toledo, Chelsea D. Painter, Ember M. Tota, M. Osman Sheikh, Alan M. V. West, Martin M. Frank, Lance Wells, Ding Xu, Roy Bicknell, Kevin D. Corbett, Jeffrey D. Esko

J Biol Chem. 2020 Feb 28; 295(9): 2804–2821. Published online 2020 Jan 21. doi: 10.1074/jbc.RA119.011639

PMCID:: PMC7049958

Article PDF–3.8M

Select item 65108864.

Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer

Matteo Bocci, Jonas Sjölund, Ewa Kurzejamska, David Lindgren, Nour-Al-Dain Marzouka, Michael Bartoschek, Mattias Höglund, Kristian Pietras

Angiogenesis. 2019; 22(1): 117–131. Published online 2018 Aug 21. doi: 10.1007/s10456-018-9642-5

PMCID:: PMC6510886

Article PDF–3.4M

Select item 38981075.

Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro

M K Ki, M H Jeoung, J R Choi, S-S Rho, Y-G Kwon, H Shim, J Chung, H J Hong, B D Song, S Lee

Oncogene. 2013 Nov 28; 32(48): 5449–5457. Published online 2013 May 6. doi: 10.1038/onc.2013.156

PMCID:: PMC3898107

Article PDF–1.6M

Select item 69203946.

Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7

Andreas Marg, Helena Escobar, Nikos Karaiskos, Stefanie A. Grunwald, Eric Metzler, Janine Kieshauer, Sascha Sauer, Diana Pasemann, Edoardo Malfatti, Dominique Mompoint, Susanna Quijano-Roy, Anastasiya Boltengagen, Joanna Schneider, Markus Schülke, Séverine Kunz, Robert Carlier, Carmen Birchmeier, Helge Amthor, Andreas Spuler, Christine Kocks, Nikolaus Rajewsky, Simone Spuler

Nat Commun. 2019; 10: 5776. Published online 2019 Dec 18. doi: 10.1038/s41467-019-13650-z

PMCID:: PMC6920394

Article PDF–2.9M

Select item 56719387.

Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface

K A Khan, A J Naylor, A Khan, P J Noy, M Mambretti, P Lodhia, J Athwal, A Korzystka, C D Buckley, B E Willcox, F Mohammed, R Bicknell

Oncogene. 2017 Nov 2; 36(44): 6097–6108. Published online 2017 Jul 3. doi: 10.1038/onc.2017.214

PMCID:: PMC5671938

Article PDF–3.5M

Select item 47249398.

Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth

Noy PJ, Lodhia P, Khan K, Zhuang X, Ward DG, Verissimo AR, Bacon A, Bicknell R

Oncogene. Author manuscript; available in PMC 2016 May 18.

Published in final edited form as: Oncogene. 2015 Nov 19; 34(47): 5821–5831. Published online 2015 Mar 9. doi: 10.1038/onc.2015.34

PMCID:: PMC4724939

Article PDF–1.1M

Select item 52721799.

Carbohydrate-binding protein CLEC14A regulates VEGFR-2– and VEGFR-3–dependent signals during angiogenesis and lymphangiogenesis

Sungwoon Lee, Seung-Sik Rho, Hyojin Park, Jeong Ae Park, Jihye Kim, In-Kyu Lee, Gou Young Koh, Naoki Mochizuki, Young-Myeong Kim, Young-Guen Kwon

J Clin Invest. 2017 Feb 1; 127(2): 457–471. Published online 2016 Dec 19. doi: 10.1172/JCI85145

PMCID:: PMC5272179

Article PDF–5.9M

Select item 228655110.

Signal peptide prediction based on analysis of experimentally verified cleavage sites

Zemin Zhang, William J. Henzel

Protein Sci. 2004 Oct; 13(10): 2819–2824. doi: 10.1110/ps.04682504

PMCID:: PMC2286551

Article PDF–125K

Select item 386171011.

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

Sara Zanivan, Federica Maione, Marco Y. Hein, Juan Ramon Hernández-Fernaud, Pawel Ostasiewicz, Enrico Giraudo, Matthias Mann

Mol Cell Proteomics. 2013 Dec; 12(12): 3599–3611. Published online 2013 Aug 26. doi: 10.1074/mcp.M113.031344

PMCID:: PMC3861710

Article PDF–2.3M

Select item 40369712.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003

Correction in:: Genome Res. 2003 Dec; 13(12): 2759.

PMCID:: PMC403697

Article PDF–120K

Select item 756688113.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Article PDF–4.8M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Article PDF–5.4M

Select item 553161115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Article PDF–2.7M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011