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Select item 105866731.

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

Patricia Aguilar-Calvo, Adela Malik, Daniel R. Sandoval, Christopher Barback, Christina D. Orrù, Heidi G. Standke, Olivia R. Thomas, Chrissa A. Dwyer, Donald P. Pizzo, Jaidev Bapat, Katrin Soldau, Ryotaro Ogawa, Mckenzie B. Riley, K. Peter R. Nilsson, Allison Kraus, Byron Caughey, Jeffrey J. Iliff, David R. Vera, Jeffrey D. Esko, Christina J. Sigurdson

PLoS Pathog. 2023 Sep; 19(9): e1011487. Published online 2023 Sep 25. doi: 10.1371/journal.ppat.1011487

PMCID:: PMC10586673

Abstract Article PDF–2.3M

Select item 98367012.

Overexpression of NDST1 Attenuates Fibrotic Response in Murine Adipose-Derived Stem Cells

Takayoshi Otsuka, Ho-Man Kan, Timothy D. Mason, Lakshmi S. Nair, Cato T. Laurencin

Stem Cells Dev. December 2022; 31(23-24): 787–798. Published online 2022 Dec 7. doi: 10.1089/scd.2022.0053

PMCID:: PMC9836701

Abstract Article PDF–1.1M

Select item 75600883.

Cerebellar Morphology and Behavioral Profiles in Mice Lacking Heparan Sulfate Ndst Gene Function

Lars Lewejohann, Srinivas R. Pallerla, Rebecca S. Schreiber, Joanna Gerula, Kay Grobe

J Dev Biol. 2020 Sep; 8(3): 13. Published online 2020 Jul 11. doi: 10.3390/jdb8030013

PMCID:: PMC7560088

Abstract Article PDF–3.2M

Select item 69406294.

Functional Cellular Anti-Tumor Mechanisms are Augmented by Genetic Proteoglycan Targeting

Purva Gupta, Scott C. Johns, So Young Kim, Roland El Ghazal, Elina I. Zuniga, Mark M. Fuster

Neoplasia. 2020 Feb; 22(2): 86–97. Published online 2019 Dec 30. doi: 10.1016/j.neo.2019.11.003

PMCID:: PMC6940629

Abstract Article PDF–1.6M

Select item 62474175.

Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy

Ditmer T. Talsma, Kirankumar Katta, Marieke A.B. Ettema, Berna Kel, Marion Kusche-Gullberg, Moh R. Daha, Coen A. Stegeman, Jacob van den Born, Lianchun Wang

Lab Invest. Author manuscript; available in PMC 2018 Nov 21.

Published in final edited form as: Lab Invest. 2018 Apr; 98(4): 427–438. Published online 2018 Jan 12. doi: 10.1038/s41374-017-0015-2

PMCID:: PMC6247417

Abstract Article PDF–1.7M

Select item 61289226.

Selective Deletion of Heparan Sulfotransferase Enzyme, Ndst1, in Donor Endothelial and Myeloid Precursor Cells Significantly Decreases Acute Allograft Rejection

Hao Chen, Sriram Ambadapadi, Dara Wakefield, Meeyong Bartee, Jordan R. Yaron, Liqiang Zhang, Stephanie A. Archer-Hartmann, Parastoo Azadi, Michelle Burgin, Chad Borges, Donghang Zheng, Kevin Ergle, Vishnu Muppala, Sufi Morshed, Kenneth Rand, William Clapp, Amanda Proudfoot, Alexandra Lucas

Sci Rep. 2018; 8: 13433. Published online 2018 Sep 7. doi: 10.1038/s41598-018-31779-7

PMCID:: PMC6128922

Abstract Article PDF–8.7M

Select item 49387257.

Functional Importance of a Proteoglycan Coreceptor in Pathologic Lymphangiogenesis

Scott C. Johns, Xin Yin, Michael Jeltsch, Joseph R. Bishop, Manuela Schuksz, Roland El Ghazal, Sarah A. Wilcox-Adelman, Kari Alitalo, Mark M. Fuster

Circ Res. 2016 Jul 8; 119(2): 210–221. Published online 2016 Jul 7. doi: 10.1161/CIRCRESAHA.116.308504

PMCID:: PMC4938725

Abstract Article PDF–1.7M

Select item 48530238.

Vascular Biomechanical Properties in Mice with Smooth Muscle Specific Deletion of Ndst1

Neeta Adhikari, Marie Billaud, Marjorie Carlson, Spencer P. Lake, Kim Ramil C. Montaniel, Rod Staggs, Weihua Guan, Dinesha Walek, Snider Desir, Brant E. Isakson, Victor H. Barocas, Jennifer L. Hall

Mol Cell Biochem. Author manuscript; available in PMC 2016 May 2.

Published in final edited form as: Mol Cell Biochem. 2014 Jan; 385(1-2): 225–238. Published online 2013 Oct 8. doi: 10.1007/s11010-013-1831-3

PMCID:: PMC4853023

Abstract Article PDF–451K

Select item 46243149.

Podocyte-specific deletion of NDST1, a key enzyme in the sulfation of heparan sulfate glycosaminoglycans, leads to abnormalities in podocyte organization in vivo

Terrel Sugar, Deborah J Wassenhove-McCarthy, Jeffrey D Esko, Toin H van Kuppevelt, Lawrence Holzman, Kevin J McCarthy

Kidney Int. Author manuscript; available in PMC 2015 Oct 28.

Published in final edited form as: Kidney Int. 2014 Feb; 85(2): 307–318. Published online 2013 Aug 7. doi: 10.1038/ki.2013.281

PMCID:: PMC4624314

Abstract Article PDF–3.1M

Select item 338173810.

Smooth Muscle Specific Deletion of Ndst1 Leads to Decreased Vessel Luminal Area and No Change in Blood Pressure in Conscious Mice

Kim Ramil Montaniel, Marie Billaud, Cassandra Graham, Sun K. Kim, Marjorie Carlson, William Zeng, Orien Zeng, Wei Pan, Brant E. Isakson, Jennifer L. Hall, Neeta Adhikari

J Cardiovasc Transl Res. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: J Cardiovasc Transl Res. 2012 Jun; 5(3): 274–279. Published online 2012 May 4. doi: 10.1007/s12265-012-9369-4

PMCID:: PMC3381738

Abstract Article PDF–515K

Select item 288546311.

Heparan Sulfate Ndst1 Regulates Vascular Smooth Muscle Cell Proliferation, Vessel Size and Vascular Remodeling

Neeta Adhikari, David L. Basi, DeWayne Townsend, Melissa Rusch, Ami Mariash, Sureni Mullegama, Adrienne Watson, Jon Larson, Sara Tan, Ben Lerman, Jeffrey D. Esko, Scott B. Selleck, Jennifer L. Hall

J Mol Cell Cardiol. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: J Mol Cell Cardiol. 2010 Aug; 49(2): 287–293. Published online 2010 Mar 4. doi: 10.1016/j.yjmcc.2010.02.022

PMCID:: PMC2885463

Article PDF–1.4M

Select item 287266212.

Loss of the Heparan Sulfate Sulfotransferase, Ndst1, in Mammary Epithelial Cells Selectively Blocks Lobuloalveolar Development in Mice

Brett E. Crawford, Omai B. Garner, Joseph R. Bishop, David Y. Zhang, Kevin T. Bush, Sanjay K. Nigam, Jeffrey D. Esko

PLoS One. 2010; 5(5): e10691. Published online 2010 May 18. doi: 10.1371/journal.pone.0010691

PMCID:: PMC2872662

Abstract Article PDF–5.8M

Select item 854659213.

Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis

Gregory J. Golden, Alejandro Gómez Toledo, Alex Marki, James T. Sorrentino, Claire Morris, Raquel J. Riley, Charlotte Spliid, Qiongyu Chen, Ingrid Cornax, Nathan E. Lewis, Nissi Varki, Dzung Le, Johan Malmström, Christofer Karlsson, Klaus Ley, Victor Nizet, Jeffrey D. Esko

mBio. 2021 Sep-Oct; 12(5): e01181-21. Published online 2021 Sep 21. doi: 10.1128/mBio.01181-21

PMCID:: PMC8546592

Abstract Article PDF–3.7M

Select item 730809014.

Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulfate production

Magali Macchi, Karine Magalon, Céline Zimmer, Elitsa Peeva, Bilal El Waly, Béatrice Brousse, Sarah Jaekel, Kay Grobe, Friedemann Kiefer, Anna Williams, Myriam Cayre, Pascale Durbec

eLife. 2020; 9: e51735. Published online 2020 Jun 9. doi: 10.7554/eLife.51735

PMCID:: PMC7308090

Abstract Article PDF–7.5M

Select item 673722515.

Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice

Maura Poli, Ferdous Anower-E-Khuda, Michela Asperti, Paola Ruzzenenti, Magdalena Gryzik, Andrea Denardo, Philip L. S. M. Gordts, Paolo Arosio, Jeffrey D. Esko

J Biol Chem. 2019 Sep 6; 294(36): 13292–13303. Published online 2019 Jul 17. doi: 10.1074/jbc.RA118.007213

Correction in:: J Biol Chem. 2020 Mar 13; 295(11): 3747.

Correction in:: J Biol Chem. 2020 Jul 24; 295(30): 10508.

PMCID:: PMC6737225

Abstract Article PDF–3.5M

Select item 500205616.

N-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions

Terrel Sugar, Deborah J. Wassenhove-McCarthy, A. Wayne Orr, Jonette Green, Toin H. van Kuppevelt, Kevin J. McCarthy

Am J Physiol Renal Physiol. 2016 May 15; 310(10): F1123–F1135. Published online 2016 Mar 2. doi: 10.1152/ajprenal.00603.2015

PMCID:: PMC5002056

Abstract Article

Select item 396008317.

Lymphatic Specific Disruption in the Fine Structure of Heparan Sulfate Inhibits Dendritic Cell Traffic and Functional T Cell Responses in the Lymph Node

Xin Yin, Scott C. Johns, Daniel Kim, Zbigniew Mikulski, Catherina L. Salanga, Tracy M. Handel, Mónica Macal, Elina I. Zúñiga, Mark M. Fuster

J Immunol. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: J Immunol. 2014 Mar 1; 192(5): 2133–2142. Published online 2014 Feb 3. doi: 10.4049/jimmunol.1301286

PMCID:: PMC3960083

Abstract Article PDF–1.9M

Select item 351675218.

N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland

Kevin T. Bush, Brett E. Crawford, Omai B. Garner, Kabir B. Nigam, Jeffrey D. Esko, Sanjay K. Nigam

J Biol Chem. 2012 Dec 7; 287(50): 42064–42070. Published online 2012 Oct 11. doi: 10.1074/jbc.M112.423327

PMCID:: PMC3516752

Abstract Article PDF–1.1M

Select item 332284419.

Undersulfation of Heparan Sulfate Restricts Differentiation Potential of Mouse Embryonic Stem Cells

Maud Forsberg, Katarina Holmborn, Soumi Kundu, Anders Dagälv, Lena Kjellén, Karin Forsberg-Nilsson

J Biol Chem. 2012 Mar 30; 287(14): 10853–10862. Published online 2012 Feb 1. doi: 10.1074/jbc.M111.337030

PMCID:: PMC3322844

Abstract Article PDF–2.0M

Select item 317280420.

Antibodies associated with heparin-induced thrombocytopenia (HIT) inhibit activated protein C generation: new insights into the prothrombotic nature of HIT

M. Anna Kowalska, Sriram Krishnaswamy, Lubica Rauova, Li Zhai, Vincent Hayes, Karine Amirikian, Jeffrey D. Esko, Daniel W. Bougie, Richard H. Aster, Douglas B. Cines, Mortimer Poncz

Blood. 2011 Sep 8; 118(10): 2882–2888. Prepublished online 2011 Jul 19. doi: 10.1182/blood-2011-02-335208

PMCID:: PMC3172804

Abstract Article

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PMC Links for Gene (Select 15531) (67)
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Holliday junction DNA helicase RuvB [Anaplasma marginale str. St. Maries]
Holliday junction DNA helicase RuvB [Anaplasma marginale str. St. Maries]
gi|56416489|ref|YP_153563.1|

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