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Select item 104118101.

Integrated bioinformatics analyses identifying potential biomarkers for type 2 diabetes mellitus and breast cancer: In SIK1-ness and health

Ilhaam Ayaz Durrani, Attya Bhatti, Peter John

PLoS One. 2023; 18(8): e0289839. Published online 2023 Aug 9. doi: 10.1371/journal.pone.0289839

PMCID:: PMC10411810

Abstract Article PDF–2.2M

Select item 52559452.

Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology

Christoph Pröschel, Jeanne N Hansen, Adil Ali, Emily Tuttle, Michelle Lacagnina, Georgia Buscaglia, Marc W Halterman, Alex R Paciorkowski

Eur J Hum Genet. 2017 Feb; 25(2): 216–221. Published online 2016 Dec 14. doi: 10.1038/ejhg.2016.145

PMCID:: PMC5255945

Abstract Article PDF–880K

Select item 43851823.

De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies

Jeanne Hansen, Chelsi Snow, Emily Tuttle, Dalia H. Ghoneim, Chun-Song Yang, Adam Spencer, Sonya A. Gunter, Christopher D. Smyser, Christina A. Gurnett, Marwan Shinawi, William B. Dobyns, James Wheless, Marc W. Halterman, Laura A. Jansen, Bryce M. Paschal, Alex R. Paciorkowski

Am J Hum Genet. 2015 Apr 2; 96(4): 682–690. doi: 10.1016/j.ajhg.2015.02.013

Correction in:: Am J Hum Genet. 2015 Jun 4; 96(6): 1009.

PMCID:: PMC4385182

Abstract Article PDF–1.8M

Select item 25187054.

TGFβ induces SIK to negatively regulate type I receptor kinase signaling

Marcin Kowanetz, Peter Lönn, Michael Vanlandewijck, Katarzyna Kowanetz, Carl-Henrik Heldin, Aristidis Moustakas

J Cell Biol. 2008 Aug 25; 182(4): 655–662. doi: 10.1083/jcb.200804107

PMCID:: PMC2518705

Abstract Article PDF–2.9M

Select item 103527425.

Down-Regulation and Clinic-Pathological Correlation of SIK-1 and SIL-1-LNC in Non-Small Cell Lung Cancer Patients

Alireza Anvarnia, Reza Panahizadeh, Habib Zarredar, Milad Asadi, Shahriyar Hashemzadeh, Mohammad Amin Vatankhah, Hamed Valizadeh, Mortaza Raeisi

Asian Pac J Cancer Prev. 2023; 24(4): 1407–1411. doi: 10.31557/APJCP.2023.24.4.1407

PMCID:: PMC10352742

Abstract Article PDF–467K

Select item 87290166.

Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network

Yangqiu Jin, Hui Wang

J Ovarian Res. 2022; 15: 3. Published online 2022 Jan 4. doi: 10.1186/s13048-021-00931-9

PMCID:: PMC8729016

Abstract Article PDF–8.4M

Select item 78854087.

Role of SIK1 in the transition of acute kidney injury into chronic kidney disease

Jinxiu Hu, Jiao Qiao, Qun Yu, Bing Liu, Junhui Zhen, Yue Liu, Qiqi Ma, Yanmei Li, Qianhui Wang, Cheng Wang, Zhimei Lv

J Transl Med. 2021; 19: 69. Published online 2021 Feb 15. doi: 10.1186/s12967-021-02717-5

PMCID:: PMC7885408

Abstract Article PDF–12M

Select item 74936568.

SIK1 Regulates CRTC2-Mediated Gluconeogenesis Signaling Pathway in Human and Mouse Liver Cells

Chang Wang, Daofei Song, Jiahui Fu, Xiuying Wen

Front Endocrinol (Lausanne) 2020; 11: 580. Published online 2020 Sep 2. doi: 10.3389/fendo.2020.00580

PMCID:: PMC7493656

Abstract Article PDF–2.1M

Select item 72641729.

Exosomal miR-130b-3p targets SIK1 to inhibit medulloblastoma tumorigenesis

Saihua Huang, Ping Xue, Xiao Han, Caiyan Zhang, Lan Yang, Lijuan Liu, Xiang Wang, Hao Li, Jinrong Fu, Yufeng Zhou

Cell Death Dis. 2020 Jun; 11(6): 408. Published online 2020 Jun 1. doi: 10.1038/s41419-020-2621-y

PMCID:: PMC7264172

Abstract Article PDF–6.3M

Select item 535687110.

Down-regulation of salt-inducible kinase 1 (SIK1) is mediated by RNF2 in hepatocarcinogenesis

Chao Qu, Yaqin Qu

Oncotarget. 2017 Jan 10; 8(2): 3144–3155. Published online 2016 Nov 29. doi: 10.18632/oncotarget.13673

PMCID:: PMC5356871

Abstract Article PDF–7.0M

Select item 422654111.

Salt-Inducible Kinase 1 (SIK1) Is Induced by Gastrin and Inhibits Migration of Gastric Adenocarcinoma Cells

Linn-Karina M. Selvik, Shalini Rao, Tonje S. Steigedal, Ildri Haltbakk, Kristine Misund, Torunn Bruland, Wenche S. Prestvik, Astrid Lægreid, Liv Thommesen

PLoS One. 2014; 9(11): e112485. Published online 2014 Nov 10. doi: 10.1371/journal.pone.0112485

PMCID:: PMC4226541

Abstract Article PDF–2.6M

Select item 690152712.

Sodium Channel Na_v1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible Kinase-1

Frédéric Gradek, Osbaldo Lopez-Charcas, Stéphanie Chadet, Lucile Poisson, Lobna Ouldamer, Caroline Goupille, Marie-Lise Jourdan, Stéphan Chevalier, Driffa Moussata, Pierre Besson, Sébastien Roger

Sci Rep. 2019; 9: 18652. Published online 2019 Dec 9. doi: 10.1038/s41598-019-55197-5

PMCID:: PMC6901527

Abstract Article PDF–2.0M

Select item 682555813.

An Lkb1-Sik axis suppresses lung tumor growth and controls differentiation

Christopher W. Murray, Jennifer J. Brady, Min K. Tsai, Chuan Li, Ian P. Winters, Rui Tang, Laura Andrejka, Rosanna K. Ma, Christian A. Kunder, Pauline Chu, Monte M. Winslow

Cancer Discov. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Cancer Discov. 2019 Nov; 9(11): 1590–1605. Published online 2019 Jul 26. doi: 10.1158/2159-8290.CD-18-1237

PMCID:: PMC6825558

Abstract Article PDF–3.2M

Select item 364095014.

LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription

Hei-Man Vincent Tang, Wei-Wei Gao, Ching-Ping Chan, Yeung-Tung Siu, Chi-Ming Wong, Kin-Hang Kok, Yick-Pang Ching, Hiroshi Takemori, Dong-Yan Jin

Retrovirology. 2013; 10: 40. Published online 2013 Apr 11. doi: 10.1186/1742-4690-10-40

PMCID:: PMC3640950

Abstract Article PDF–1.4M

Select item 333996615.

Transcriptional Induction of Salt-inducible Kinase 1 by Transforming Growth Factor β Leads to Negative Regulation of Type I Receptor Signaling in Cooperation with the Smurf2 Ubiquitin Ligase

Peter Lönn, Michael Vanlandewijck, Erna Raja, Marcin Kowanetz, Yukihide Watanabe, Katarzyna Kowanetz, Eleftheria Vasilaki, Carl-Henrik Heldin, Aristidis Moustakas

J Biol Chem. 2012 Apr 13; 287(16): 12867–12878. Published online 2012 Feb 29. doi: 10.1074/jbc.M111.307249

PMCID:: PMC3339966

Abstract Article PDF–1.9M

Select item 310642416.

Salt-inducible kinase 1 is present in lung alveolar epithelial cells and regulates active sodium transport

Kristina Eneling, Jiwang Chen, Lynn C. Welch, Hiroshi Takemori, Jacob I. Sznajder, Alejandro M. Bertorello

Biochem Biophys Res Commun. Author manuscript; available in PMC 2012 May 27.

Published in final edited form as: Biochem Biophys Res Commun. 2011 May 27; 409(1): 28–33. Published online 2011 Apr 28. doi: 10.1016/j.bbrc.2011.04.100