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Select item 89342721.

Platelet glycoprotein Ibα provides radiation protection

Adam Corken, Sanchita P. Ghosh, Ruofei Du, Marjan Boerma, Jerry Ware, Rupak Pathak

Radiother Oncol. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Radiother Oncol. 2022 Feb; 167: 143–148. Published online 2021 Dec 28. doi: 10.1016/j.radonc.2021.12.030

PMCID:: PMC8934272

Abstract Article PDF–1.1M

Select item 49291482.

Defective association of the platelet glycoprotein Ib-IX complex with the glycosphingolipid-enriched membrane domain inhibits murine thrombus and atheroma formation

Hao Zhou, Yali Ran, Qi Da, Tanner S. Shaw, Dan Shang, Anilkumar K. Reddy, José A. López, Christie M. Ballantyne, Jerry Ware, Huaizhu Wu, Yuandong Peng

J Immunol. Author manuscript; available in PMC 2017 Jul 1.

Published in final edited form as: J Immunol. 2016 Jul 1; 197(1): 288–295. Published online 2016 May 20. doi: 10.4049/jimmunol.1501946

PMCID:: PMC4929148

Abstract Article PDF–2.2M

Select item 44298703.

Genetic deletion of platelet Glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis

Ekaterina K. Koltsova, Prithu Sundd, Alessandro Zarpellon, Hui Ouyang, Zbigniew Mikulski, Antonella Zampolli, Zaverio M. Ruggeri, Klaus Ley

Thromb Haemost. Author manuscript; available in PMC 2015 May 13.

Published in final edited form as: Thromb Haemost. 2014 Dec; 112(6): 1252–1263. Published online 2014 Aug 7. doi: 10.1160/TH14-02-0130

PMCID:: PMC4429870

Abstract Article PDF–1.5M

Select item 104451244.

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Joshua H. Bourne, Joana Campos, Sophie J. Hopkin, Katharine Whitworth, James Palis, Yotis A. Senis, Julie Rayes, Asif J. Iqbal, Alexander Brill

Front Immunol. 2023; 14: 1226196. Published online 2023 Aug 9. doi: 10.3389/fimmu.2023.1226196

PMCID:: PMC10445124

Abstract Article PDF–1.6M

Select item 74799535.

von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions

Hannah K. Lohmeier, Tricia L. Slobodianuk, Sachiko Kanaji, Sandra L. Haberichter, Robert R. Montgomery, Veronica H. Flood

Blood Adv. 2020 Sep 8; 4(17): 4065–4068. Published online 2020 Aug 31. doi: 10.1182/bloodadvances.2020002629

PMCID:: PMC7479953

Abstract Article PDF–698K

Select item 54775196.

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

Yunmei Wang, Huiyun Gao, Can Shi, Paul W. Erhardt, Alexander Pavlovsky, Dmitry A. Soloviev, Kamila Bledzka, Valentin Ustinov, Liang Zhu, Jun Qin, Adam D. Munday, Jose Lopez, Edward Plow, Daniel I. Simon

Nat Commun. 2017; 8: 15559. Published online 2017 May 30. doi: 10.1038/ncomms15559

Correction in:: Nat Commun. 2017; 8: 16124.

PMCID:: PMC5477519

Abstract Article PDF–1.2M

Select item 42639877.

Exploiting the kinetic interplay between GPIbα–VWF binding interfaces to regulate hemostasis and thrombosis

Jianchung Chen, Hairu Zhou, Alexander Diacovo, X. Long Zheng, Jonas Emsley, Thomas G. Diacovo

Blood. 2014 Dec 11; 124(25): 3799–3807. Prepublished online 2014 Oct 7. doi: 10.1182/blood-2014-04-569392

PMCID:: PMC4263987

Abstract Article

Select item 38139668.

Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl₃-induced occlusive thrombus formation in the inferior vena cava of mice

M. Joglekar, Jerry Ware, Jin Xu, Malinda E. C. Fitzgerald, T. Kent Gartner

Platelets. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Platelets. 2013; 24(3): 10.3109/09537104.2012.696746. Published online 2012 Jun 21. doi: 10.3109/09537104.2012.696746

PMCID:: PMC3813966

Abstract Article PDF–2.1M

Select item 37732829.

Hypoxia, such as encountered at high altitude, promotes deep vein thrombosis in mice

A. Brill, G. L. Suidan, D. D. Wagner

J Thromb Haemost. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Thromb Haemost. 2013 Sep; 11(9): 1773–1775. doi: 10.1111/jth.12310

PMCID:: PMC3773282

Article PDF–106K

Select item 364377010.

Red blood cells mediate the onset of thrombosis in the ferric chloride murine model

Justin D. Barr, Anil K. Chauhan, Gilbert V. Schaeffer, Jessica K. Hansen, David G. Motto

Blood. 2013 May 2; 121(18): 3733–3741. Prepublished online 2013 Jan 23. doi: 10.1182/blood-2012-11-468983

PMCID:: PMC3643770

Abstract Article

Select item 320484111.

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies

Conglei Li, Siavash Piran, Pingguo Chen, Sean Lang, Alessandro Zarpellon, Joseph W. Jin, Guangheng Zhu, Adili Reheman, Dianne E. van der Wal, Elisa K. Simpson, Ran Ni, Peter L. Gross, Jerry Ware, Zaverio M. Ruggeri, John Freedman, Heyu Ni

J Clin Invest. 2011 Nov 1; 121(11): 4537–4547. Published online 2011 Oct 24. doi: 10.1172/JCI57850

PMCID:: PMC3204841

Abstract Article PDF–1.4M

Select item 188562112.

Platelet glycoprotein Ibα supports experimental lung metastasis

Shashank Jain, Masahiko Zuka, Jungling Liu, Susan Russell, Judith Dent, José A. Guerrero, Jane Forsyth, Brigid Maruszak, T. Kent Gartner, Brunhilde Felding-Habermann, Jerry Ware

Proc Natl Acad Sci U S A. 2007 May 22; 104(21): 9024–9028. Published online 2007 May 9. doi: 10.1073/pnas.0700625104

PMCID:: PMC1885621

Abstract Article PDF–564K

Select item 163655113.

The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

Wolfgang Bergmeier, Crystal L. Piffath, Tobias Goerge, Stephen M. Cifuni, Zaverio M. Ruggeri, Jerry Ware, Denisa D. Wagner

Proc Natl Acad Sci U S A. 2006 Nov 7; 103(45): 16900–16905. Published online 2006 Oct 30. doi: 10.1073/pnas.0608207103

PMCID:: PMC1636551

Abstract Article PDF–417K

Select item 1601014.

Generation and rescue of a murine model of platelet dysfunction: The Bernard-Soulier syndrome

Jerry Ware, Susan Russell, Zaverio M. Ruggeri

Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6): 2803–2808. Published online 2000 Mar 7. doi: 10.1073/pnas.050582097

PMCID:: PMC16010

Abstract Article PDF–210K

Select item 706617215.

Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb

David Köhler, Tiago Granja, Julia Volz, Michael Koeppen, Harald F. Langer, Georg Hansmann, Ekaterina Legchenko, Tobias Geisler, Tamam Bakchoul, Claudia Eggstein, Helene A. Häberle, Bernhard Nieswandt, Peter Rosenberger

Nat Commun. 2020; 11: 1315. Published online 2020 Mar 11. doi: 10.1038/s41467-020-14958-x

PMCID:: PMC7066172

Abstract Article PDF–2.0M

Select item 457387116.

Platelets induce apoptosis via membrane-bound FasL

Rebecca I. Schleicher, Frank Reichenbach, Peter Kraft, Anil Kumar, Mario Lescan, Franziska Todt, Kerstin Göbel, Ingo Hilgendorf, Tobias Geisler, Axel Bauer, Marcus Olbrich, Martin Schaller, Sebastian Wesselborg, Lorraine O’Reilly, Sven G. Meuth, Klaus Schulze-Osthoff, Meinrad Gawaz, Xuri Li, Christoph Kleinschnitz, Frank Edlich, Harald F. Langer

Blood. 2015 Sep 17; 126(12): 1483–1493. Prepublished online 2015 Jul 31. doi: 10.1182/blood-2013-12-544445

Correction in:: Blood. 2016 Jan 14; 127(2): 270.

PMCID:: PMC4573871

Abstract Article

Select item 439647317.

Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage

Issaka Yougbaré, Sean Lang, Hong Yang, Pingguo Chen, Xu Zhao, Wei-She Tai, Darko Zdravic, Brian Vadasz, Conglei Li, Siavash Piran, Alexandra Marshall, Guangheng Zhu, Heidi Tiller, Mette Kjaer Killie, Shelley Boyd, Howard Leong-Poi, Xiao-Yan Wen, Bjorn Skogen, S. Lee Adamson, John Freedman, Heyu Ni

J Clin Invest. 2015 Apr 1; 125(4): 1545–1556. Published online 2015 Mar 16. doi: 10.1172/JCI77820

PMCID:: PMC4396473

Abstract Article PDF–3.9M

Select item 379546418.

Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia

Taisuke Kanaji, Sachiko Kanaji, Robert R. Montgomery, Shailendra B. Patel, Peter J. Newman

Blood. 2013 Oct 10; 122(15): 2732–2742. Prepublished online 2013 Aug 7. doi: 10.1182/blood-2013-06-510461

PMCID:: PMC3795464

Abstract Article

Select item 375535319.

Platelet IKKβ Deficiency Increases Mouse Arterial Neointima Formation via Delayed Glycoprotein Ibα Shedding

Shujian Wei, Huan Wang, Guoying Zhang, Ying Lu, Xiaofei An, Shumei Ren, Yunmei Wang, Yuguo Chen, James G White, Chunxiang Zhang, Daniel I. Simon, Chaodong Wu, Zhenyu Li, Yuqing Huo

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2): 241–248. Published online 2012 Dec 13. doi: 10.1161/ATVBAHA.112.300781