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Select item 104042651.

Developmental changes in cerebral NAD and neuroenergetics of an antioxidant compromised mouse model of schizophrenia

Radek Skupienski, Pascal Steullet, Kim Q. Do, Lijing Xin

Transl Psychiatry. 2023; 13: 275. Published online 2023 Aug 5. doi: 10.1038/s41398-023-02568-2

PMCID:: PMC10404265

Abstract Article PDF–1.3M

Select item 102270082.

Prenatal exposure to benzo[a]pyrene depletes ovarian reserve and masculinizes embryonic ovarian germ cell transcriptome transgenerationally

Jinhwan Lim, Toshihiro Shioda, Kelli F. Malott, Keiko Shioda, Junko Odajima, Kathleen N. Leon Parada, Julie Nguyen, Samantha Getze, Melody Lee, Jonathon Nguyen, Samantha Reshel Blakeley, Vienna Trinh, Hong-An Truong, Ulrike Luderer

Sci Rep. 2023; 13: 8671. Published online 2023 May 29. doi: 10.1038/s41598-023-35494-w

PMCID:: PMC10227008

Abstract Article PDF–2.4M

Select item 97340613.

Alterations in TRN-anterodorsal thalamocortical circuits affect sleep architecture and homeostatic processes in oxidative stress vulnerable Gclm^−/− mice

Christina Czekus, Pascal Steullet, Albert Orero López, Ivan Bozic, Thomas Rusterholz, Mojtaba Bandarabadi, Kim Q. Do, Carolina Gutierrez Herrera

Mol Psychiatry. 2022; 27(11): 4394–4406. Published online 2022 Jul 28. doi: 10.1038/s41380-022-01700-w

PMCID:: PMC9734061

Abstract Article PDF–4.3M

Select item 91989514.

Glutathione deficiency decreases lipid droplet stores and increases reactive oxygen species in mouse oocytes

Kelli F Malott, Samantha Reshel, Laura Ortiz, Ulrike Luderer

Biol Reprod. 2022 Jun; 106(6): 1218–1231. Published online 2022 Mar 3. doi: 10.1093/biolre/ioac032

PMCID:: PMC9198951

Abstract Article PDF–1.6M

Select item 87151105.

Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment

Christopher M. Schaupp, Dianne Botta, Collin C. White, David K. Scoville, Sengkeo Srinouanprachanh, Theo K. Bammler, James MacDonald, Terrance J. Kavanagh

Redox Biol. 2022 Feb; 49: 102213. Published online 2021 Dec 20. doi: 10.1016/j.redox.2021.102213

PMCID:: PMC8715110

Abstract Article PDF–2.3M

Select item 82011176.

GSH-Independent Induction of ER Stress during Hypoglycaemia in the Retinal Cells of Mice

Daria Fresia, Enrica Cannizzaro, Angelica Borgo, Raphaël Roduit

J Clin Med. 2021 Jun; 10(11): 2529. Published online 2021 Jun 7. doi: 10.3390/jcm10112529

PMCID:: PMC8201117

Abstract Article PDF–2.7M

Select item 71867797.

Antioxidant supplementation partially rescues accelerated ovarian follicle loss, but not oocyte quality, of glutathione-deficient mice

Jinhwan Lim, Samiha Ali, Lisa S Liao, Emily S Nguyen, Laura Ortiz, Samantha Reshel, Ulrike Luderer

Biol Reprod. 2020 Apr; 102(5): 1065–1079. Published online 2020 Jan 17. doi: 10.1093/biolre/ioaa009

PMCID:: PMC7186779

Abstract Article PDF–1.4M

Select item 66345458.

Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors

Pascal Steullet, Jan-Harry Cabungcal, Anita Kulak, Rudolf Kraftsik, Ying Chen, Timothy P. Dalton, Michel Cuenod, Kim Q. Do

J Neurosci. 2010 Feb 17; 30(7): 2547–2558. doi: 10.1523/JNEUROSCI.3857-09.2010

PMCID:: PMC6634545

Abstract Article PDF–3.4M

Select item 58495149.

Decreased glutathione levels cause overt motor neuron degeneration in hSOD1^WT overexpressing mice

Kelby M. Killoy, Benjamin A. Harlan, Mariana Pehar, Kristi L. Helke, Jeffrey A. Johnson, Marcelo R. Vargas

Exp Neurol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Exp Neurol. 2018 Apr; 302: 129–135. Published online 2018 Jan 4. doi: 10.1016/j.expneurol.2018.01.004

PMCID:: PMC5849514

Abstract Article PDF–598K

Select item 483863110.

Glutamate Cysteine Ligase—Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage

Suzie Lavoie, Pascal Steullet, Anita Kulak, Frederic Preitner, Kim Q. Do, Pierre J. Magistretti

Front Physiol. 2016; 7: 142. Published online 2016 Apr 21. doi: 10.3389/fphys.2016.00142

PMCID:: PMC4838631

Abstract Article PDF–1.0M

Select item 472326211.

Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia

Yiting Zhang, Nathaniel W. Hodgson, Malav S. Trivedi, Hamid M. Abdolmaleky, Margot Fournier, Michel Cuenod, Kim Quang Do, Richard C. Deth

PLoS One. 2016; 11(1): e0146797. Published online 2016 Jan 22. doi: 10.1371/journal.pone.0146797

PMCID:: PMC4723262

Abstract Article PDF–2.2M

Select item 454162412.

Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure

Jinhwan Lim, Brooke N. Nakamura, Isaac Mohar, Terrance J. Kavanagh, Ulrike Luderer

Endocrinology. 2015 Sep; 156(9): 3329–3343. Published online 2015 Jun 17. doi: 10.1210/en.2015-1206

PMCID:: PMC4541624

Abstract Article

Select item 404540613.

Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells

G. Giordano, L. Li, C.C. White, F.M. Farin, H.W. Wilkerson, T.J. Kavanagh, L.G. Costa

J Neurochem. Author manuscript; available in PMC 2014 Jun 4.

Published in final edited form as: J Neurochem. 2009 Apr; 109(2): 525–538. Published online 2009 Feb 7. doi: 10.1111/j.1471-4159.2009.05969.x

PMCID:: PMC4045406

Abstract Article PDF–2.9M

Select item 385622414.

In Utero Exposure to Benzo[a]pyrene Increases Adiposity and Causes Hepatic Steatosis in Female Mice, and Glutathione Deficiency Is Protective

Laura Ortiz, Brooke Nakamura, Xia Li., Bruce Blumberg, Ulrike Luderer

Toxicol Lett. Author manuscript; available in PMC 2014 Nov 25.

Published in final edited form as: Toxicol Lett. 2013 Nov 25; 223(2): 10.1016/j.toxlet.2013.09.017. Published online 2013 Oct 6. doi: 10.1016/j.toxlet.2013.09.017

PMCID:: PMC3856224

Abstract Article PDF–819K

Select item 377032515.

Functional significance of glutamate–cysteine ligase modifier for erythrocyte survival in vitro and in vivo

M Föller, I S Harris, A Elia, R John, F Lang, T J Kavanagh, T W Mak

Cell Death Differ. 2013 Oct; 20(10): 1350–1358. Published online 2013 Jun 21. doi: 10.1038/cdd.2013.70

PMCID:: PMC3770325

Abstract Article PDF–2.6M

Select item 373211916.

Control of Angiogenesis Dictated by Picomolar Superoxide Levels

Shyamal C Bir, Xinggui Shen, Terrance J Kavanagh, Christopher G Kevil, Christopher B Pattillo

Free Radic Biol Med. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Free Radic Biol Med. 2013 Oct; 63: 135–142. Published online 2013 May 16. doi: 10.1016/j.freeradbiomed.2013.05.015

PMCID:: PMC3732119

Abstract Article PDF–3.0M

Select item 370743717.

Glutathione Deficiency in Gclm Null Mice Results in Complex I Inhibition and Dopamine Depletion Following Paraquat Administration

Li-Ping Liang, Terrance J. Kavanagh, Manisha Patel

Toxicol Sci. 2013 Aug; 134(2): 366–373. Published online 2013 May 30. doi: 10.1093/toxsci/kft112

PMCID:: PMC3707437

Abstract Article PDF–2.2M

Select item 369351518.

Low-Level Domoic Acid Protects Mouse Cerebellar Granule Neurons from Acute Neurotoxicity: Role of Glutathione

Gennaro Giordano, Terrance J. Kavanagh, Elaine M. Faustman, Collin C. White, Lucio G. Costa

Toxicol Sci. 2013 Apr; 132(2): 399–408. Published online 2013 Jan 12. doi: 10.1093/toxsci/kft002

PMCID:: PMC3693515

Abstract Article PDF–2.4M

Select item 366458119.

The Glutathione Synthesis Gene Gclm Modulates Amphiphilic Polymer-Coated CdSe/ZnS Quantum Dot–Induced Lung Inflammation in Mice

Lisa A. McConnachie, Dianne Botta, Collin C. White, Chad S. Weldy, Hui-Wen Wilkerson, Jianbo Yu, Russell Dills, Xiaozhong Yu, William C. Griffith, Elaine M. Faustman, Federico M. Farin, Sean E. Gill, William C. Parks, Xiaoge Hu, Xiaohu Gao, David L. Eaton, Terrance J. Kavanagh

PLoS One. 2013; 8(5): e64165. Published online 2013 May 27. doi: 10.1371/journal.pone.0064165

PMCID:: PMC3664581

Abstract Article PDF–606K

Select item 362503120.

Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice

Chad S. Weldy, Ian P. Luttrell, Collin C. White, Vicki Morgan-Stevenson, Theo K. Bammler, Richard P. Beyer, Zahra Afsharinejad, Francis Kim, Kanchan Chitaley, Terrance J. Kavanagh

Free Radic Biol Med. Author manuscript; available in PMC 2013 Sep 15.

Published in final edited form as: Free Radic Biol Med. 2012 Sep 15; 53(6): 1264–1278. Published online 2012 Jul 21. doi: 10.1016/j.freeradbiomed.2012.07.006