PMC Links for Gene (Select 146057) - PMC

Michiko Kitano-Takahashi, Hiroyuki Morita, Shin Kondo, Kayoko Tomizawa, Ryohei Kato, Michikazu Tanio, Yoshiko Shirota, Hiroshi Takahashi, Shigetoshi Sugio, Toshiyuki Kohno

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Jul 1; 63(Pt 7): 602–604. Published online 2007 Jun 15. doi: 10.1107/S1744309107028783

PMCID:: PMC2335129

Abstract Article PDF–130K

Select item 13779405.

Autosomal dominant cerebellar ataxia type III: linkage in a large British family to a 7.6-cM region on chromosome 15q14-21.3.

P F Worth, P Giunti, C Gardner-Thorpe, P H Dixon, M B Davis, N W Wood

Am J Hum Genet. 1999 Aug; 65(2): 420–426. doi: 10.1086/302495

PMCID:: PMC1377940

Summary PDF–228K

Select item 101048076.

Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis

Frances M. Bashore, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran, Alison D. Axtman

Sci Rep. 2023; 13: 6118. Published online 2023 Apr 14. doi: 10.1038/s41598-023-32854-4

PMCID:: PMC10104807

Abstract Article PDF–3.8M

Select item 87521277.

Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies

Ivan Rosa e Silva, Lucia Binó, Christopher M. Johnson, Trevor J. Rutherford, David Neuhaus, Antonina Andreeva, Lukáš Čajánek, Mark van Breugel

Structure. 2022 Jan 6; 30(1): 114–128.e9. doi: 10.1016/j.str.2021.08.007

PMCID:: PMC8752127

Abstract Article

Select item 80722208.

A complex of distal appendage–associated kinases linked to human disease regulates ciliary trafficking and stability

Abdelhalim Loukil, Chloe Barrington, Sarah C. Goetz

Proc Natl Acad Sci U S A. 2021 Apr 20; 118(16): e2018740118. Published online 2021 Apr 12. doi: 10.1073/pnas.2018740118

PMCID:: PMC8072220

Abstract Article PDF–11M

Select item 67814409.

Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation

Chien-Hui Lo, I-Hsuan Lin, T. Tony Yang, Yen-Chun Huang, Barbara E. Tanos, Po-Chun Chou, Chih-Wei Chang, Yeou-Guang Tsay, Jung-Chi Liao, Won-Jing Wang

J Cell Biol. 2019 Oct 7; 218(10): 3489–3505. Published online 2019 Aug 27. doi: 10.1083/jcb.201811142

PMCID:: PMC6781440

Abstract Article PDF–4.4M

Select item 580205910.

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

Laura M. Taylor, Pamela J. McMillan, Nicole F. Liachko, Timothy J. Strovas, Bernardino Ghetti, Thomas D. Bird, C. Dirk Keene, Brian C. Kraemer

Mol Neurodegener. 2018; 13: 7. Published online 2018 Feb 6. doi: 10.1186/s13024-018-0237-9

PMCID:: PMC5802059

Abstract Article PDF–2.5M

Select item 410484611.

Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole

Lukáš Čajánek, Erich A. Nigg

Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2841–E2850. Published online 2014 Jun 30. doi: 10.1073/pnas.1401777111

PMCID:: PMC4104846

Abstract Article PDF–1.8M

Select item 373932612.

TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development

Michale Bouskila, Noor Esoof, Laurie Gay, Emily H. Fang, Maria Deak, Michael J. Begley, Lewis C. Cantley, Alan Prescott, Kate G. Storey, Dario R. Alessi

Biochem J. Author manuscript; available in PMC 2013 Aug 9.

Published in final edited form as: Biochem J. 2011 Jul 1; 437(1): 157–167. doi: 10.1042/BJ20110276

PMCID:: PMC3739326

Abstract Article PDF–4.5M

Select item 531914213.

TTBK2 circular RNA promotes glioma malignancy by regulating miR-217/HNF1β/Derlin-1 pathway

Jian Zheng, Xiaobai Liu, Yixue Xue, Wei Gong, Jun Ma, Zhuo Xi, Zhongyou Que, Yunhui Liu

J Hematol Oncol. 2017; 10: 52. Published online 2017 Feb 20. doi: 10.1186/s13045-017-0422-2

PMCID:: PMC5319142

Abstract Article PDF–24M

Select item 489366414.

MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment

Si-Hyung Lee, Mi-Sun Lee, Tae-Ik Choi, Hyowon Hong, Jun-Young Seo, Cheol-Hee Kim, Joon Kim

Sci Rep. 2016; 6: 27284. Published online 2016 Jun 6. doi: 10.1038/srep27284

PMCID:: PMC4893664

Abstract Article PDF–1.3M

Select item 425608715.

The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43

Nicole F. Liachko, Pamela J. McMillan, Timothy J. Strovas, Elaine Loomis, Lynne Greenup, Jill R. Murrell, Bernardino Ghetti, Murray A. Raskind, Thomas J. Montine, Thomas D. Bird, James B. Leverenz, Brian C. Kraemer

PLoS Genet. 2014 Dec; 10(12): e1004803. Published online 2014 Dec 4. doi: 10.1371/journal.pgen.1004803

PMCID:: PMC4256087

Abstract Article PDF–1.4M

Select item 285053916.

The ulcerative colitis marker protein WAFL interacts with accessory proteins in endocytosis

You Fu Pan, Ing-Marie Viklund, Heng Hang Tsai, Sven Pettersson, Ichiro N. Maruyama

Int J Biol Sci. 2010; 6(2): 163–171. Published online 2010 Mar 29. doi: 10.7150/ijbs.6.163

PMCID:: PMC2850539

Abstract Article PDF–523K

Select item 620775717.

M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole

Ning Huang, Donghui Zhang, Fangyuan Li, Peiyuan Chai, Song Wang, Junlin Teng, Jianguo Chen

Nat Commun. 2018; 9: 4511. Published online 2018 Oct 30. doi: 10.1038/s41467-018-06990-9

PMCID:: PMC6207757

Abstract Article PDF–4.0M

Select item 630781718.

Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability

Emily Bowie, Ryan Norris, Kathryn V. Anderson, Sarah C. Goetz

PLoS Genet. 2018 Dec; 14(12): e1007844. Published online 2018 Dec 10. doi: 10.1371/journal.pgen.1007844

PMCID:: PMC6307817

Abstract Article PDF–3.8M

Select item 349618419.

The Spinocerebellar Ataxia-associated Gene Tau Tubulin Kinase 2 (TTBK2) Controls the Initiation of Ciliogenesis

Sarah C. Goetz, Karel F. Liem, Jr., Kathryn V. Anderson

Cell. Author manuscript; available in PMC 2013 Nov 9.

Published in final edited form as: Cell. 2012 Nov 9; 151(4): 847–858. doi: 10.1016/j.cell.2012.10.010

PMCID:: PMC3496184

Abstract Article PDF–3.0M

Select item 455581620.

TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation

Takashi Watanabe, Mai Kakeno, Toshinori Matsui, Ikuko Sugiyama, Nariko Arimura, Kenji Matsuzawa, Aya Shirahige, Fumiyoshi Ishidate, Tomoki Nishioka, Shinichiro Taya, Mikio Hoshino, Kozo Kaibuchi

J Cell Biol. 2015 Aug 31; 210(5): 737–751. doi: 10.1083/jcb.201412075