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Select item 102976351.

Induction of Senescence by Loss of Gata4 in Cardiac Fibroblasts

Zhentao Zhang, Gabriella Shayani, Yanping Xu, Ashley Kim, Yurim Hong, Haiyue Feng, Hua Zhu

Cells. 2023 Jun; 12(12): 1652. Published online 2023 Jun 17. doi: 10.3390/cells12121652

PMCID:: PMC10297635

Abstract Article PDF–6.1M

Select item 98513992.

Hepatic GATA4 regulates cholesterol and triglyceride homeostasis in collaboration with LXRs

Lara Bideyan, Maykel López Rodríguez, Christina Priest, John P. Kennelly, Yajing Gao, Alessandra Ferrari, Prashant Rajbhandari, An-Chieh Feng, Sergei G. Tevosian, Stephen T. Smale, Peter Tontonoz

Genes Dev. 2022 Nov-Dec; 36(21-24): 1129–1144. doi: 10.1101/gad.350145.122

PMCID:: PMC9851399

Abstract Article PDF–3.3M

Select item 76438813.

Cell culture system to assay candidate genes and molecular pathways implicated in congenital diaphragmatic hernias

Eric L. Bogenschutz, Elizabeth M. Sefton, Gabrielle Kardon

Dev Biol. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Dev Biol. 2020 Nov 1; 467(1-2): 30–38. Published online 2020 Aug 19. doi: 10.1016/j.ydbio.2020.07.013

PMCID:: PMC7643881

Abstract Article PDF–1.1M

Select item 67778104.

Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload–associated maladaptation

Mona Malek Mohammadi, Aya Abouissa, Isyatul Azizah, Yinou Xie, Julio Cordero, Amir Shirvani, Anna Gigina, Maren Engelhardt, Felix A. Trogisch, Robert Geffers, Gergana Dobreva, Johann Bauersachs, Joerg Heineke

JCI Insight. 2019 Aug 22; 4(16): e128336. Published online 2019 Aug 22. doi: 10.1172/jci.insight.128336

PMCID:: PMC6777810

Abstract Article PDF–16M

Select item 64966915.

Histone modifications interact with DNA methylation at the GATA4 promoter during differentiation of mesenchymal stem cells into cardiomyocyte‐like cells

Hao Xu, Qin Yi, Chunmei Yang, Yue Wang, Jie Tian, Jing Zhu

Cell Prolif. 2016 Jun; 49(3): 315–329. Published online 2016 Apr 26. doi: 10.1111/cpr.12253

PMCID:: PMC6496691

Abstract Article PDF–2.1M

Select item 60530636.

GATA4 Directly Regulates Runx2 Expression and Osteoblast Differentiation

Aysha B Khalid, Alexandria V Slayden, Jerusha Kumpati, Chanel D Perry, Maria Angeles Lillo Osuna, Samantha R Arroyo, Gustavo A Miranda‐Carboni, Susan A Krum

JBMR Plus. 2018 Mar; 2(2): 81–91. Published online 2018 Jan 3. doi: 10.1002/jbm4.10027

PMCID:: PMC6053063

Abstract Article PDF–5.3M

Select item 58338527.

Dural effects of oxidative stress on cardiomyogenesis via Gata4 transcription and protein ubiquitination

Tao Li, Xia Zhang, Kesheng Jiang, Jing Liu, Zhiqiang Liu

Cell Death Dis. 2018 Feb; 9(2): 246. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0281-y

PMCID:: PMC5833852

Abstract Article PDF–2.3M

Select item 52863678.

The transcription factor GATA4 promotes myocardial regeneration in neonatal mice

Mona Malek Mohammadi, Badder Kattih, Andrea Grund, Natali Froese, Mortimer Korf‐Klingebiel, Anna Gigina, Ulrike Schrameck, Carsten Rudat, Qiangrong Liang, Andreas Kispert, Kai C Wollert, Johann Bauersachs, Joerg Heineke

EMBO Mol Med. 2017 Feb; 9(2): 265–279. Published online 2017 Jan 4. doi: 10.15252/emmm.201606602

Correction in:: EMBO Mol Med. 2019 Jun; 11(6): e10678.

PMCID:: PMC5286367

Abstract Article PDF–1.9M

Select item 52229809.

Polygenic Causes of Congenital Diaphragmatic Hernia Produce Common Lung Pathologies

Patricia K. Donahoe, Mauro Longoni, Frances A. High

Am J Pathol. 2016 Oct; 186(10): 2532–2543. doi: 10.1016/j.ajpath.2016.07.006

PMCID:: PMC5222980

Abstract Article PDF–1.4M

Select item 510153110.

Gata4 is critical to maintain gut barrier function and mucosal integrity following epithelial injury

David Lepage, Élise Bélanger, Christine Jones, Sarah Tremblay, Joannie M. Allaire, Joannie Bruneau, Claude Asselin, Nathalie Perreault, Alfredo Menendez, Fernand-Pierre Gendron, Francois Boudreau

Sci Rep. 2016; 6: 36776. Published online 2016 Nov 9. doi: 10.1038/srep36776

PMCID:: PMC5101531

Abstract Article PDF–2.5M

Select item 489178911.

GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells

Anja Schrade, Antti Kyrönlahti, Oyediran Akinrinade, Marjut Pihlajoki, Simon Fischer, Verena Martinez Rodriguez, Kerstin Otte, Vidya Velagapudi, Jorma Toppari, David B. Wilson, Markku Heikinheimo

Endocrinology. 2016 Jun; 157(6): 2416–2431. Published online 2016 Mar 14. doi: 10.1210/en.2015-1927

PMCID:: PMC4891789

Abstract Article

Select item 456067212.

Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesis

Rajani M. George, Katherine L. Hahn, Alan Rawls, Robert S. Viger, Jeanne Wilson-Rawls

Reproduction. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: Reproduction. 2015 Oct; 150(4): 383–394. Published online 2015 Jul 16. doi: 10.1530/REP-15-0226

PMCID:: PMC4560672

Abstract Article PDF–1.2M

Select item 439876213.

GATA4 Is a Key Regulator of Steroidogenesis and Glycolysis in Mouse Leydig Cells

Anja Schrade, Antti Kyrönlahti, Oyediran Akinrinade, Marjut Pihlajoki, Merja Häkkinen, Simon Fischer, Tero-Pekka Alastalo, Vidya Velagapudi, Jorma Toppari, David B. Wilson, Markku Heikinheimo

Endocrinology. 2015 May; 156(5): 1860–1872. Published online 2015 Feb 10. doi: 10.1210/en.2014-1931

PMCID:: PMC4398762

Abstract Article

Select item 369484514.

DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation

Masaaki Oda, Yuichi Kumaki, Masaki Shigeta, Lars Martin Jakt, Chisa Matsuoka, Akiko Yamagiwa, Hitoshi Niwa, Masaki Okano

PLoS Genet. 2013 Jun; 9(6): e1003574. Published online 2013 Jun 27. doi: 10.1371/journal.pgen.1003574

PMCID:: PMC3694845

Abstract Article PDF–1.4M

Select item 323677115.

An Ebox Element in the Proximal Gata4 Promoter Is Required for Gata4 Expression In Vivo

Alain Boulende Sab, Marie-France Bouchard, Mélanie Béland, Bruno Prud'homme, Ouliana Souchkova, Robert S. Viger, Nicolas Pilon

PLoS One. 2011; 6(12): e29038. Published online 2011 Dec 13. doi: 10.1371/journal.pone.0029038

PMCID:: PMC3236771

Abstract Article PDF–974K

Select item 316329216.

Loss of intestinal GATA4 prevents diet-induced obesity and promotes insulin sensitivity in mice

Jay V. Patankar, Prakash G. Chandak, Sascha Obrowsky, Thomas Pfeifer, Clemens Diwoky, Andreas Uellen, Wolfgang Sattler, Rudolf Stollberger, Gerald Hoefler, Akos Heinemann, Michele Battle, Stephen Duncan, Dagmar Kratky, Sanja Levak-Frank

Am J Physiol Endocrinol Metab. 2011 Mar; 300(3): E478–E488. Published online 2010 Dec 21. doi: 10.1152/ajpendo.00457.2010

PMCID:: PMC3163292

Abstract Article

Select item 314569817.

Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo

Jop H. van Berlo, John W. Elrod, Bruce J. Aronow, William T. Pu, Jeffery D. Molkentin

Proc Natl Acad Sci U S A. 2011 Jul 26; 108(30): 12331–12336. Published online 2011 Jul 11. doi: 10.1073/pnas.1104499108

PMCID:: PMC3145698

Abstract Article PDF–805K

Select item 305873218.

Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart

Ah-Mee Park, Hiroko Nagase, Lingling Liu, Shilpashree Vinod Kumar, Nava Szwergold, Chi-Ming Wong, Yuichiro J. Suzuki

Cardiovasc Res. 2011 Apr 1; 90(1): 97–104. Published online 2010 Nov 16. doi: 10.1093/cvr/cvq361

PMCID:: PMC3058732

Abstract Article PDF–423K

Select item 298179819.

Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine

Eva Beuling, Ilona M Kerkhof, Grace A Nicksa, Michael J Giuffrida, Jamie Haywood, Daniel J aan de Kerk, Christina M Piaseckyj, William T Pu, Terry L Buchmiller, Paul A Dawson, Stephen D Krasinski

Gut. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Gut. 2010 Jul; 59(7): 888–895. doi: 10.1136/gut.2009.204990