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Select item 87596081.

CD116⁺ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages

Elza Evren, Emma Ringqvist, Jean-Marc Doisne, Anna Thaller, Natalie Sleiers, Richard A. Flavell, James P. Di Santo, Tim Willinger

J Exp Med. 2022 Feb 7; 219(2): e20210987. Published online 2022 Jan 12. doi: 10.1084/jem.20210987

PMCID:: PMC8759608

Abstract Article PDF–9.6M

Select item 42542582.

Characterization of CSF2RA mutation related juvenile pulmonary alveolar proteinosis

Jenna Hildebrandt, Ebru Yalcin, Hans-Georg Bresser, Guzin Cinel, Monika Gappa, Alireza Haghighi, Nural Kiper, Soheila Khalilzadeh, Karl Reiter, John Sayer, Nicolaus Schwerk, Anke Sibbersen, Sabine Van Daele, Georg Nübling, Peter Lohse, Matthias Griese

Orphanet J Rare Dis. 2014; 9: 171. Published online 2014 Nov 26. doi: 10.1186/s13023-014-0171-z

PMCID:: PMC4254258

Abstract Article PDF–778K

Select item 33622073.

Defective Leukocyte GM-CSF Receptor (CD116) Expression and Function in Inflammatory Bowel Disease

Jonathan I. Goldstein, Douglas J. Kominsky, Nicole Jacobson, Brittelle Bowers, Kirsten Regalia, Gregory L. Austin, Melinda Yousefi, Michael T. Falta, Andrew P. Fontenot, Mark E. Gerich, Lucy Golden-Mason, Sean P. Colgan

Gastroenterology. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Gastroenterology. 2011 Jul; 141(1): 208–216. Published online 2011 Apr 7. doi: 10.1053/j.gastro.2011.03.060

PMCID:: PMC3362207

Abstract Article PDF–2.0M

Select item 25858514.

Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRα gene in the X chromosome pseudoautosomal region 1

Margarita Martinez-Moczygemba, Minh L. Doan, Okan Elidemir, Leland L. Fan, Sau Wai Cheung, Jonathan T. Lei, James P. Moore, Ghamartaj Tavana, Lora R. Lewis, Yiming Zhu, Donna M. Muzny, Richard A. Gibbs, David P. Huston

J Exp Med. 2008 Nov 24; 205(12): 2711–2716. doi: 10.1084/jem.20080759

PMCID:: PMC2585851

Abstract Article PDF–1.7M

Select item 25858455.

Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA

Takuji Suzuki, Takuro Sakagami, Bruce K. Rubin, Lawrence M. Nogee, Robert E. Wood, Sarah L. Zimmerman, Teresa Smolarek, Megan K. Dishop, Susan E. Wert, Jeffrey A. Whitsett, Gregory Grabowski, Brenna C. Carey, Carrie Stevens, Johannes C.M. van der Loo, Bruce C. Trapnell

J Exp Med. 2008 Nov 24; 205(12): 2703–2710. doi: 10.1084/jem.20080990

PMCID:: PMC2585845

Abstract Article PDF–2.7M

Select item 24949596.

Crystallization and preliminary X-ray diffraction analysis of the ternary human GM-CSF receptor complex

Guido Hansen, Timothy R. Hercus, Yibin Xu, Angel F. Lopez, Michael W. Parker, William J. McKinstry

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Aug 1; 64(Pt 8): 711–714. Published online 2008 Jul 5. doi: 10.1107/S1744309108019404

PMCID:: PMC2494959

Abstract Article PDF–302K

Select item 4020497.

Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.

D P Gearing, J A King, N M Gough, N A Nicola

EMBO J. 1989 Dec 1; 8(12): 3667–3676. doi: 10.1002/j.1460-2075.1989.tb08541.x

PMCID:: PMC402049

Summary Page Browse PDF–2.6M

Select item 3328248.

Cloning of a potentially soluble receptor for human GM-CSF.

A Ashworth, A Kraft

Nucleic Acids Res. 1990 Dec 11; 18(23): 7178. doi: 10.1093/nar/18.23.7178

PMCID:: PMC332824

Summary Page Browse PDF–153K

Select item 524759.

Identification and molecular cloning of a soluble human granulocyte-macrophage colony-stimulating factor receptor.

M A Raines, L Liu, S G Quan, V Joe, J F DiPersio, D W Golde

Proc Natl Acad Sci U S A. 1991 Sep 15; 88(18): 8203–8207. doi: 10.1073/pnas.88.18.8203

PMCID:: PMC52475

Summary Page Browse PDF–1.1M

Select item 5237910.

A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain.

K E Crosier, G G Wong, B Mathey-Prevot, D G Nathan, C A Sieff

Proc Natl Acad Sci U S A. 1991 Sep 1; 88(17): 7744–7748. doi: 10.1073/pnas.88.17.7744

PMCID:: PMC52379

Summary Page Browse PDF–1.1M

Select item 891793511.

A murine model of hereditary pulmonary alveolar proteinosis caused by homozygous Csf2ra gene disruption

Kenjiro Shima, Paritha Arumugam, Anthony Sallese, Yuko Horio, Yan Ma, Cole Trapnell, Matthew Wessendarp, Claudia Chalk, Cormac McCarthy, Brenna C. Carey, Bruce C. Trapnell, Takuji Suzuki

Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1; 322(3): L438–L448. Published online 2022 Jan 19. doi: 10.1152/ajplung.00175.2021

PMCID:: PMC8917935

Abstract Article

Select item 685070012.

Neutrophil GM‐CSF receptor dynamics in acute lung injury

Silvia De Alessandris, G. John Ferguson, Alison J. Dodd, Jatinder K. Juss, Abhinandan Devaprasad, Siân Piper, Owen Wyatt, Helen Killick, Dominic J. Corkill, E. Suzanne Cohen, Aridaman Pandit, Timothy R.D.J. Radstake, Rosalind Simmonds, Alison M. Condliffe, Matthew A. Sleeman, Andrew S. Cowburn, Donna K. Finch, Edwin R. Chilvers

J Leukoc Biol. 2019 Jun; 105(6): 1183–1194. Published online 2019 Apr 3. doi: 10.1002/JLB.3MA0918-347R

PMCID:: PMC6850700

Abstract Article PDF–659K

Select item 639184613.

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease

Lee A Denson, Ingrid Jurickova, Rebekah Karns, Kelly A Shaw, David J Cutler, David Okou, C Alexander Valencia, Anne Dodd, Kajari Mondal, Bruce J Aronow, Yael Haberman, Aaron Linn, Adam Price, Ramona Bezold, Kathleen Lake, Kimberly Jackson, Thomas D Walters, Anne Griffiths, Robert N Baldassano, Joshua D Noe, Jeffrey S Hyams, Wallace V Crandall, Barbara S Kirschner, Melvin B Heyman, Scott Snapper, Stephen L Guthery, Marla C Dubinsky, Neal S Leleiko, Anthony R Otley, Ramnik J Xavier, Christine Stevens, Mark J Daly, Michael E Zwick, Subra Kugathasan

Inflamm Bowel Dis. 2019 Mar; 25(3): 547–560. Published online 2018 Aug 13. doi: 10.1093/ibd/izy265

PMCID:: PMC6391846

Abstract Article PDF–1.5M

Select item 564726014.

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity

Igal Ifergan, Todd S. Davidson, Hania Kebir, Dan Xu, Daphne Palacios-Macapagal, Jennifer Cann, Jane M. Rodgers, Zoe N. Hunter, Camille L. Pittet, Sara Beddow, Clare A. Jones, Alexandre Prat, Matthew A. Sleeman, Stephen D. Miller

J Autoimmun. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: J Autoimmun. 2017 Nov; 84: 1–11. Published online 2017 Jun 20. doi: 10.1016/j.jaut.2017.06.005

PMCID:: PMC5647260

Abstract Article PDF–3.5M

Select item 28353515.

The laminin receptor modulates granulocyte–macrophage colony-stimulating factor receptor complex formation and modulates its signaling

Jian Chen, Juan M. Cárcamo, Oriana Bórquez-Ojeda, Hediye Erdjument-Bromage, Paul Tempst, David W. Golde

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14000–14005. Published online 2003 Nov 12. doi: 10.1073/pnas.2334584100

PMCID:: PMC283535

Abstract Article PDF–515K

Select item 532406416.

Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption

Chih-Yung Chiu, Shih-Chi Su, Wen-Lang Fan, Shen-Hao Lai, Ming-Han Tsai, Shih-Hsiang Chen, Kin-Sun Wong, Wen-Hung Chung

Sci Rep. 2017; 7: 43469. Published online 2017 Feb 24. doi: 10.1038/srep43469

PMCID:: PMC5324064

Abstract Article PDF–1.0M

Select item 5523117.

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

K Hayashida, T Kitamura, D M Gorman, K Arai, T Yokota, A Miyajima

Proc Natl Acad Sci U S A. 1990 Dec; 87(24): 9655–9659. doi: 10.1073/pnas.87.24.9655

PMCID:: PMC55231

Summary Page Browse PDF–1.2M

Select item 347831218.

Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2

Ping-Hung Chen, Fan-Ching Chien, Sue-Ping Lee, Woan-Eng Chan, I-Hsuan Lin, Chun-Shan Liu, Fang-Jen Lee, Jiann-Shiun Lai, Peilin Chen, Hsin-Fang Yang-Yen, Jeffrey Jong-Young Yen

Cell Cycle. 2012 Oct 1; 11(19): 3611–3626. doi: 10.4161/cc.21920

PMCID:: PMC3478312

Abstract Article PDF–6.8M

Select item 39546619.

Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.

J M Woodcock, B Zacharakis, G Plaetinck, C J Bagley, S Qiyu, T R Hercus, J Tavernier, A F Lopez

EMBO J. 1994 Nov 1; 13(21): 5176–5185. doi: 10.1002/j.1460-2075.1994.tb06848.x

PMCID:: PMC395466

Summary Page Browse PDF–1.9M

Select item 374693220.

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

Tory P. Johnson, Karan Patel, Kory R. Johnson, Dragan Maric, Peter A. Calabresi, Rodrigo Hasbun, Avindra Nath

Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33): 13588–13593. Published online 2013 Jul 29. doi: 10.1073/pnas.1308673110

PMCID:: PMC3746932

Abstract Article PDF–1002K

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