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Select item 58044901.

Gene Expression, and Fatigue in Puerto Rican Men during Radiotherapy for Prostate Cancer: an exploratory study

Velda J. Gonzalez, Leorey N. Saligan, Brooke L. Fridley, Humberto Ortiz-Zuazaga, Lauren S. Aaronson

P R Health Sci J. Author manuscript; available in PMC 2018 Feb 8.

Published in final edited form as: P R Health Sci J. 2017 Dec; 36(4): 223–231.

PMCID:: PMC5804490

Abstract Article PDF–883K

Select item 49650512.

Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach

Rajneesh Srivastava, Yang Zhang, Xiwen Xiong, Xiaoning Zhang, Xiaoyan Pan, X. Charlie Dong, Suthat Liangpunsakul, Sarath Chandra Janga

PLoS One. 2016; 11(7): e0160228. Published online 2016 Jul 28. doi: 10.1371/journal.pone.0160228

PMCID:: PMC4965051

Abstract Article PDF–4.7M

Select item 38823723.

Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle

Emmani BM Nascimento, Megan E. Osler, Juleen R. Zierath

Am J Physiol Endocrinol Metab. 2013 Dec 1; 305(11): E1408–E1414. Published online 2013 Oct 15. doi: 10.1152/ajpendo.00212.2013

PMCID:: PMC3882372

Abstract Article

Select item 38326114.

Regulatory Effects of Sestrin 3 (SESN3) in BCR-ABL Expressing Cells

Eliza Vakana, Ahmet Dirim Arslan, Amy Szilard, Jessica K. Altman, Leonidas C. Platanias

PLoS One. 2013; 8(11): e78780. Published online 2013 Nov 18. doi: 10.1371/journal.pone.0078780

PMCID:: PMC3832611

Abstract Article PDF–1.1M

Select item 26575535.

Repression of Sestrin Family Genes Contributes to Oncogenic Ras-Induced ROS Up-Regulation and Genetic Instability

Pavel B. Kopnin, Larissa S. Agapova, Boris P. Kopnin, Peter M. Chumakov

Cancer Res. Author manuscript; available in PMC 2009 Mar 18.

Published in final edited form as: Cancer Res. 2007 May 15; 67(10): 4671–4678. doi: 10.1158/0008-5472.CAN-06-2466

PMCID:: PMC2657553

Abstract Article PDF–1.0M

Select item 83766396.

Colon and liver tissue damage detection using methylated SESN3 and PTK2B genes in circulating cell-free DNA in patients with acute graft-versus-host disease

Miguel Waterhouse, Sandra Pennisi, Dietmar Pfeifer, Max Deuter, Nikolas von Bubnoff, Florian Scherer, Tim Strüssmann, Claudia Wehr, Justus Duyster, Hartmut Bertz, Jürgen Finke, Jesus Duque-Afonso

Bone Marrow Transplant. 2021; 56(2): 327–333. Published online 2020 Oct 20. doi: 10.1038/s41409-020-01090-z

Correction in:: Bone Marrow Transplant. 2021; 56(10): 2616.

PMCID:: PMC8376639

Abstract Article PDF–709K

Select item 60755157.

Sestrin-3 modulation is essential for therapeutic efficacy of cucurbitacin B in lung cancer cells

Naghma Khan, Farah Jajeh, Mohammad Imran Khan, Eiman Mukhtar, Sameh M. Shabana, Hasan Mukhtar

Carcinogenesis. 2017 Feb; 38(2): 184–195. Published online 2016 Nov 23. doi: 10.1093/carcin/bgw124

PMCID:: PMC6075515

Abstract Article PDF–6.9M

Select item 40801638.

The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury

Xinqin Kang, Kateryna Petyaykina, Rongya Tao, Xiwen Xiong, X. Charlie Dong, Suthat Liangpunsakul

Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1; 307(1): G58–G65. Published online 2014 May 15. doi: 10.1152/ajpgi.00373.2013

PMCID:: PMC4080163

Abstract Article

Select item 30386659.

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

Veronique Nogueira, Youngkyu Park, Chia-Chen Chen, Pei-Zhang Xu, Mei-Ling Chen, Ivana Tonic, Terry Unterman, Nissim Hay

Cancer Cell. Author manuscript; available in PMC 2011 Feb 14.

Published in final edited form as: Cancer Cell. 2008 Dec 9; 14(6): 458–470. doi: 10.1016/j.ccr.2008.11.003

PMCID:: PMC3038665

Abstract Article PDF–3.0M

Select item 880656910.

Oncogenic role of early growth response-1 in liver cancer through the regulation of the microRNA-675/sestrin 3 and the Wnt/β-catenin signaling pathway

Lingling Zhang, Ran Ren, Xue Yang, Yiman Ge, Xiajun Zhang, Hongping Yuan

Bioengineered. 2021; 12(1): 5305–5322. Published online 2021 Aug 19. doi: 10.1080/21655979.2021.1964889

PMCID:: PMC8806569

Abstract Article PDF–6.0M

Select item 872119111.

The functions and roles of sestrins in regulating human diseases

Yitong Chen, Tingben Huang, Zhou Yu, Qiong Yu, Ying Wang, Ji’an Hu, Jiejun Shi, Guoli Yang

Cell Mol Biol Lett. 2022; 27: 2. Published online 2022 Jan 3. doi: 10.1186/s11658-021-00302-8

PMCID:: PMC8721191

Abstract Article PDF–2.1M

Select item 730685312.

Circulating Sestrin Levels Are Increased in Hypertension Patients

Cao Fang, Zicong Yang, Lei Shi, Tao Zeng, Ying Shi, Ling Liu, Hongtao Liu, Yingzhong Lin

Dis Markers. 2020; 2020: 3787295. Published online 2020 Jun 12. doi: 10.1155/2020/3787295

PMCID:: PMC7306853

Abstract Article PDF–629K

Select item 667983513.

Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis

Joanna Kozak, Paulina Wdowiak, Ryszard Maciejewski, Anna Torres

Mol Cell Biochem. 2019; 459(1): 21–34. Published online 2019 May 9. doi: 10.1007/s11010-019-03547-2

PMCID:: PMC6679835

Abstract Article PDF–1.6M

Select item 361073014.

Ras-induced ROS upregulation affecting cell proliferation is connected with cell type-specific alterations of HSF1/SESN3/p21^Cip1/WAF1 pathways

Maria Zamkova, Natalia Khromova, Boris P. Kopnin, Pavel Kopnin

Cell Cycle. 2013 Mar 1; 12(5): 826–836. doi: 10.4161/cc.23723

PMCID:: PMC3610730

Abstract Article PDF–2.2M

Select item 567194415.

FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3

M Rupp, J Hagenbuchner, B Rass, H Fiegl, U Kiechl-Kohlendorfer, P Obexer, M J Ausserlechner

Oncogene. 2017 Nov 2; 36(44): 6190–6203. Published online 2017 Sep 4. doi: 10.1038/onc.2017.288

PMCID:: PMC5671944

Abstract Article PDF–6.1M

Select item 462757616.

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Michael R. Johnson, Jacques Behmoaras, Leonardo Bottolo, Michelle L. Krishnan, Katharina Pernhorst, Paola L. Meza Santoscoy, Tiziana Rossetti, Doug Speed, Prashant K. Srivastava, Marc Chadeau-Hyam, Nabil Hajji, Aleksandra Dabrowska, Maxime Rotival, Banafsheh Razzaghi, Stjepana Kovac, Klaus Wanisch, Federico W. Grillo, Anna Slaviero, Sarah R. Langley, Kirill Shkura, Paolo Roncon, Tisham De, Manuel Mattheisen, Pitt Niehusmann, Terence J. O’Brien, Slave Petrovski, Marec von Lehe, Per Hoffmann, Johan Eriksson, Alison J. Coffey, Sven Cichon, Matthew Walker, Michele Simonato, Bénédicte Danis, Manuela Mazzuferi, Patrik Foerch, Susanne Schoch, Vincenzo De Paola, Rafal M. Kaminski, Vincent T. Cunliffe, Albert J. Becker, Enrico Petretto

Nat Commun. Author manuscript; available in PMC 2015 Oct 30.

Published in final edited form as: Nat Commun. 2015; 6: 6031. Published online 2015 Jan 23. doi: 10.1038/ncomms7031

PMCID:: PMC4627576

Abstract Article PDF–1.7M

Select item 469801717.

Sestrin2 is a leucine sensor for the mTORC1 pathway

Rachel L. Wolfson, Lynne Chantranupong, Robert A. Saxton, Kuang Shen, Sonia M. Scaria, Jason R. Cantor, David M. Sabatini

Science. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Science. 2016 Jan 1; 351(6268): 43–48. Published online 2015 Oct 8. doi: 10.1126/science.aab2674

PMCID:: PMC4698017

Abstract Article PDF–1.4M

Select item 303198418.

FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor

Chia-Chen Chen, Sang-Min Jeon, Prashanth T. Bhaskar, Veronique Nogueira, Deepa Sundararajan, Ivana Tonic, Youngkyu Park, Nissim Hay

Dev Cell. Author manuscript; available in PMC 2011 Apr 20.

Published in final edited form as: Dev Cell. 2010 Apr 20; 18(4): 592–604. doi: 10.1016/j.devcel.2010.03.008

PMCID:: PMC3031984

Abstract Article PDF–1.5M

Select item 368736519.

Maintenance of metabolic homeostasis by Sestrin 2 and 3

Jun Hee Lee, Andrei V. Budanov, Saswata Talukdar, Eek Joong Park, Hae Li Park, Hwan-Woo Park, Gautam Bandyopadhyay, Ning Li, Mariam Aghajan, Insook Jang, Amber M. Wolfe, Guy A. Perkins, Mark H. Ellisman, Ethan Bier, Miriam Scadeng, Marc Foretz, Benoit Viollet, Jerrold Olefsky, Michael Karin

Cell Metab. Author manuscript; available in PMC 2013 Jun 20.

Published in final edited form as: Cell Metab. 2012 Sep 5; 16(3): 311–321. doi: 10.1016/j.cmet.2012.08.004

PMCID:: PMC3687365

Abstract Article PDF–5.0M

Select item 422386620.

The Sestrins interact with GATOR2 to negatively regulate the amino acid sensing pathway upstream of mTORC1

Lynne Chantranupong, Rachel L. Wolfson, Jose M. Orozco, Robert A. Saxton, Sonia M. Scaria, Liron Bar-Peled, Eric Spooner, Marta Isasa, Steven P. Gygi, David M. Sabatini

Cell Rep. Author manuscript; available in PMC 2014 Nov 7.

Published in final edited form as: Cell Rep. 2014 Oct 9; 9(1): 1–8. Published online 2014 Sep 25. doi: 10.1016/j.celrep.2014.09.014

PMCID:: PMC4223866

Abstract Article PDF–616K

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