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Items: 1 to 20 of 43

1.
FHL1 promotes chikungunya and o’nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design
Wern Hann Ng, Xiang Liu, Zheng L. Ling, Camilla N. O. Santos, Lucas S. Magalhães, Andrew J. Kueh, Marco J. Herold, Adam Taylor, Joseph R. Freitas, Sandra Koit, Sainan Wang, Andrew R. Lloyd, Mauro M. Teixeira, Andres Merits, Roque P. Almeida, Nicholas J. C. King, Suresh Mahalingam
Nat Commun. 2023; 14: 6605. Published online 2023 Oct 26. doi: 10.1038/s41467-023-42330-2
PMCID:
PMC10603155
AbstractArticlePDF–1.8M
2.
Cardiomyopathy and altered integrin-actin signaling in Fhl1 mutant female mice
Akatsuki Kubota, Martí Juanola-Falgarona, Valentina Emmanuele, Maria Jose Sanchez-Quintero, Shingo Kariya, Fusako Sera, Shunichi Homma, Kurenai Tanji, Catarina M Quinzii, Michio Hirano
Hum Mol Genet. 2019 Jan 15; 28(2): 209–219. Published online 2018 Sep 26. doi: 10.1093/hmg/ddy299
PMCID:
PMC7594173
AbstractArticlePDF–32M
3.
FHL-1 is not involved in pressure overload-induced maladaptive right ventricular remodeling and dysfunction
Christine Veith, Dariusch Neghabian, Himal Luitel, Jochen Wilhelm, Bakytbek Egemnazarov, Caja Muntanjohl, Jan-Hendrik Fischer, Bhola Kumar Dahal, Ralph Theo Schermuly, Hossein Ardeschir Ghofrani, Friedrich Grimminger, Ludger Fink, Grazyna Kwapiszewska, Norbert Weissmann, Akylbek Sydykov
Basic Res Cardiol. 2020; 115(2): 17. Published online 2020 Jan 24. doi: 10.1007/s00395-019-0767-5
PMCID:
PMC6981327
AbstractArticlePDF–1.9M
4.
KyoT2 downregulates airway remodeling in asthma
Mei Hu, Hai-Feng Ou-Yang, Xing-Peng Han, Xin-Yu Ti, Chang-Gui Wu
Int J Clin Exp Pathol. 2015; 8(11): 14171–14179. Published online 2015 Nov 1.
PMCID:
PMC4713516
AbstractArticlePDF–1.0M
5.
Fhl1 W122S causes loss of protein function and late-onset mild myopathy
Valentina Emmanuele, Akatsuki Kubota, Beatriz Garcia-Diaz, Caterina Garone, Hasan O. Akman, Daniel Sánchez-Gutiérrez, Luis M. Escudero, Shingo Kariya, Shunichi Homma, Kurenai Tanji, Catarina M. Quinzii, Michio Hirano
Hum Mol Genet. 2015 Feb 1; 24(3): 714–726. Published online 2014 Sep 30. doi: 10.1093/hmg/ddu490
PMCID:
PMC4342698
AbstractArticlePDF–1007K
6.
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice
Farah Sheikh, Anna Raskin, Pao-Hsien Chu, Stephan Lange, Andrea A. Domenighetti, Ming Zheng, Xingqun Liang, Tong Zhang, Toshitaka Yajima, Yusu Gu, Nancy D. Dalton, Sushil K. Mahata, Gerald W. Dorn, II, Joan Heller-Brown, Kirk L. Peterson, Jeffrey H. Omens, Andrew D. McCulloch, Ju Chen
J Clin Invest. 2008 Dec 1; 118(12): 3870–3880. Published online 2008 Nov 3. doi: 10.1172/JCI34472
Correction in:
J Clin Invest. 2012 Apr 2; 122(4): 1584.
PMCID:
PMC2575833
AbstractArticlePDF–2.9M
7.
MiR-183-5p induced by saturated fatty acids regulates the myogenic differentiation by directly targeting FHL1 in C2C12 myoblasts
Mai Thi Nguyen, Kyung-Ho Min, Wan Lee
BMB Rep. 2020 Nov 30; 53(11): 605–610. Published online 2020 Nov 30. doi: 10.5483/BMBRep.2020.53.11.175
PMCID:
PMC7704217
AbstractArticlePDF–4.7M
8.
Structure and Function of the CSL-KyoT2 Corepressor Complex – a Negative Regulator of Notch Signaling
Kelly J. Collins, Zhenyu Yuan, Rhett A. Kovall
Structure. Author manuscript; available in PMC 2015 Jan 7.
Published in final edited form as: Structure. 2014 Jan 7; 22(1): 70–81. Published online 2013 Nov 27. doi: 10.1016/j.str.2013.10.010
PMCID:
PMC3947186
AbstractArticlePDF–4.5M
9.
5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy
Danos C. Christodoulou, Hiroko Wakimoto, Kenji Onoue, Seda Eminaga, Joshua M. Gorham, Steve R. DePalma, Daniel S. Herman, Polakit Teekakirikul, David A. Conner, David M. McKean, Andrea A. Domenighetti, Anton Aboukhalil, Stephen Chang, Gyan Srivastava, Barbara McDonough, Philip L. De Jager, Ju Chen, Martha L. Bulyk, Jochen D. Muehlschlegel, Christine E. Seidman, J.G. Seidman
J Clin Invest. 2014 Mar 3; 124(3): 1364–1370. Published online 2014 Feb 10. doi: 10.1172/JCI70108
PMCID:
PMC3934171
AbstractArticlePDF–943K
10.
Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice
Andrea A. Domenighetti, Pao-Hsien Chu, Tongbin Wu, Farah Sheikh, David S. Gokhin, Ling T. Guo, Ziyou Cui, Angela K. Peter, Danos C. Christodoulou, Michael G. Parfenov, Joshua M. Gorham, Daniel Y. Li, Indroneal Banerjee, Xianyin Lai, Frank A. Witzmann, Christine E. Seidman, Jonathan G. Seidman, Aldrin V. Gomes, G. Diane Shelton, Richard L. Lieber, Ju Chen
Hum Mol Genet. 2014 Jan 1; 23(1): 209–225. Published online 2013 Aug 23. doi: 10.1093/hmg/ddt412
PMCID:
PMC3916749
AbstractArticlePDF–1.7M
11.
SLIMMER (FHL1B/KyoT3) Interacts with the Proapoptotic Protein Siva-1 (CD27BP) and Delays Skeletal Myoblast Apoptosis
Denny L. Cottle, Meagan J. McGrath, Brendan R. Wilding, Belinda S. Cowling, Jordan M. Kane, Colleen E. D'Arcy, Melissa Holdsworth, Irene Hatzinisiriou, Mark Prescott, Susan Brown, Christina A. Mitchell
J Biol Chem. 2009 Sep 25; 284(39): 26964–26977. Published online 2009 Jul 29. doi: 10.1074/jbc.M109.036293
PMCID:
PMC2786031
AbstractArticlePDF–5.9M
12.
Four-and-a-half LIM domains proteins are novel regulators of the protein kinase D pathway in cardiac myocytes
Konstantina Stathopoulou, Friederike Cuello, Alexandra J. Candasamy, Elizabeth M. Kemp, Elisabeth Ehler, Robert S. Haworth, Metin Avkiran
Biochem J. 2014 Feb 1; 457(Pt 3): 451–461. Prepublished online 2013 Nov 13. Published online 2014 Jan 10. doi: 10.1042/BJ20131026
PMCID:
PMC3927927
AbstractArticlePDF–1.3M
13.
LIM Protein KyoT2 Negatively Regulates Transcription by Association with the RBP-J DNA-Binding Protein
Yoshihito Taniguchi, Takahisa Furukawa, Tin Tun, Hua Han, Tasuku Honjo
Mol Cell Biol. 1998 Jan; 18(1): 644–654. doi: 10.1128/mcb.18.1.644
PMCID:
PMC121531
AbstractArticlePDF–1.0M
14.
Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes
Judith Krysiak, Andreas Unger, Lisa Beckendorf, Nazha Hamdani, Marion von Frieling-Salewsky, Margaret M. Redfield, Cris G. dos Remedios, Farah Sheikh, Ulrich Gergs, Peter Boknik, Wolfgang A. Linke
Nat Commun. 2018; 9: 262. Published online 2018 Jan 17. doi: 10.1038/s41467-017-02483-3
PMCID:
PMC5772059
AbstractArticlePDF–5.9M
15.
Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy
Belinda S. Cowling, Meagan J. McGrath, Mai-Anh Nguyen, Denny L. Cottle, Anthony J. Kee, Susan Brown, Joachim Schessl, Yaqun Zou, Josephine Joya, Carsten G. Bönnemann, Edna C. Hardeman, Christina A. Mitchell
J Cell Biol. 2008 Dec 15; 183(6): 1033–1048. doi: 10.1083/jcb.200804077
PMCID:
PMC2600747
AbstractArticlePDF–3.5M
16.
The T-Cell Oncogenic Protein HOX11 Activates Aldh1 Expression in NIH 3T3 Cells but Represses Its Expression in Mouse Spleen Development
Wayne K. Greene, Sabine Bahn, Norma Masson, Terence H. Rabbitts
Mol Cell Biol. 1998 Dec; 18(12): 7030–7037. doi: 10.1128/mcb.18.12.7030
PMCID:
PMC109285
AbstractArticlePDF–1.9M
17.
Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina
Joel B. Miesfeld, Myung-soon Moon, Amy N. Riesenberg, Ashley N. Contreras, Rhett A. Kovall, Nadean L. Brown
Sci Rep. 2018; 8: 10195. Published online 2018 Jul 5. doi: 10.1038/s41598-018-28420-y
PMCID:
PMC6033939
AbstractArticlePDF–3.4M
18.
Src-mediated phosphorylation converts FHL1 from tumor suppressor to tumor promoter
Xiang Wang, Xiaofan Wei, Yang Yuan, Qingrui Sun, Jun Zhan, Jing Zhang, Yan Tang, Feng Li, Lihua Ding, Qinong Ye, Hongquan Zhang
J Cell Biol. 2018 Apr 2; 217(4): 1335–1351. doi: 10.1083/jcb.201708064
PMCID:
PMC5881501
AbstractArticlePDF–3.2M
19.
Multimodal profiling of the transcriptional regulatory landscape of the developing mouse cortex identifies Neurog2 as a key epigenome remodeler
Florian Noack, Silvia Vangelisti, Gerald Raffl, Madalena Carido, Jeisimhan Diwakar, Faye Chong, Boyan Bonev
Nat Neurosci. 2022; 25(2): 154–167. Published online 2022 Feb 7. doi: 10.1038/s41593-021-01002-4
PMCID:
PMC8825286
AbstractArticlePDF–24M
20.
A Novel Mechanism Involving Four-and-a-half LIM Domain Protein-1 and Extracellular Signal-regulated Kinase-2 Regulates Titin Phosphorylation and Mechanics
Anna Raskin, Stephan Lange, Katherine Banares, Robert C. Lyon, Anke Zieseniss, Leonard K. Lee, Katrina G. Yamazaki, Henk L. Granzier, Carol C. Gregorio, Andrew D. McCulloch, Jeffrey H. Omens, Farah Sheikh
J Biol Chem. 2012 Aug 24; 287(35): 29273–29284. Published online 2012 Jul 9. doi: 10.1074/jbc.M112.372839
PMCID:
PMC3436149
AbstractArticlePDF–3.1M

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