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Select item 54117571.

Amelogenesis imperfecta caused by N-terminal enamelin point mutations in mice and men is driven by endoplasmic reticulum stress

Steven J. Brookes, Martin J. Barron, Claire E.L. Smith, James A. Poulter, Alan J. Mighell, Chris F. Inglehearn, Catriona J. Brown, Helen Rodd, Jennifer Kirkham, Michael J. Dixon

Hum Mol Genet. 2017 May 15; 26(10): 1863–1876. Published online 2017 Mar 11. doi: 10.1093/hmg/ddx090

PMCID:: PMC5411757

Abstract Article PDF–1.5M

Select item 42832032.

Characterization of Periodontal Structures of Enamelin-Null Mice

Hsun-Liang Chan, William V. Giannobile, Robert M. Eber, James P. Simmer, Jan C. Hu

J Periodontol. Author manuscript; available in PMC 2015 Jan 5.

Published in final edited form as: J Periodontol. 2014 Jan; 85(1): 195–203. Published online 2013 May 7. doi: 10.1902/jop.2013.120651

PMCID:: PMC4283203

Abstract Article PDF–1.1M

Select item 35912183.

Bodyweight Assessment of Enamelin Null Mice

Albert H.-L. Chan, Rangsiyakorn Lertlam, James P. Simmer, Chia-Ning Wang, Jan C. C. Hu

Biomed Res Int. 2013; 2013: 246861. Published online 2012 Dec 26. doi: 10.1155/2013/246861

PMCID:: PMC3591218

Abstract Article PDF–901K

Select item 27544084.

Identifying Promoter Elements Necessary for Enamelin Tissue-Specific Expression

Petros Papagerakis, Yuanyuan Hu, Ling Ye, Jerry Q. Feng, James P. Simmer, Jan C.-C. Hu

Cells Tissues Organs. 2008 Dec; 189(1-4): 98–104. Published online 2008 Aug 15. doi: 10.1159/000151429

PMCID:: PMC2754408

Abstract Article PDF–550K

Select item 27019705.

Distal cis-regulatory elements are required for tissue-specific expression of enamelin (Enam)

Yuanyuan Hu, Petros Papagerakis, Ling Ye, Jerry Q. Feng, James P. Simmer, Jan C-C. Hu

Eur J Oral Sci. Author manuscript; available in PMC 2009 Jun 25.

Published in final edited form as: Eur J Oral Sci. 2008 Apr; 116(2): 113–123. doi: 10.1111/j.1600-0722.2007.00519.x

PMCID:: PMC2701970

Abstract Article PDF–3.9M

Select item 112446406.

The phosphorylation of serine⁵⁵ in enamelin is essential for murine amelogenesis

Changchun Dong, Bikash Lamichhane, Hajime Yamazaki, Brent Vasquez, Jingya Wang, Yongxu Zhang, Jian Q. Feng, Henry C. Margolis, Elia Beniash, Xiaofang Wang

Matrix Biol. Author manuscript; available in PMC 2024 Jul 12.

Published in final edited form as: Matrix Biol. 2022 Aug; 111: 245–263. Published online 2022 Jul 9. doi: 10.1016/j.matbio.2022.07.001

PMCID:: PMC11244640

Abstract Article PDF–3.2M

Select item 51182107.

Ultrastructure of early amelogenesis in wild‐type, Amelx^‐/‐, and Enam^‐/‐ mice: enamel ribbon initiation on dentin mineral and ribbon orientation by ameloblasts

Charles E. Smith, Yuanyuan Hu, Jan C.‐C. Hu, James P. Simmer

Mol Genet Genomic Med. 2016 Nov; 4(6): 662–683. Published online 2016 Oct 16. doi: 10.1002/mgg3.253

PMCID:: PMC5118210

Abstract Article PDF–21M

Select item 39459758.

Enamelin Is Critical for Ameloblast Integrity and Enamel Ultrastructure Formation

Jan C.-C. Hu, Yuanyuan Hu, Yuhe Lu, Charles E. Smith, Rangsiyakorn Lertlam, John Timothy Wright, Cynthia Suggs, Marc D. McKee, Elia Beniash, M. Enamul Kabir, James P. Simmer

PLoS One. 2014; 9(3): e89303. Published online 2014 Mar 6. doi: 10.1371/journal.pone.0089303

PMCID:: PMC3945975

Abstract Article PDF–5.9M

Select item 37185749.

Phenotype-Genotype Correlations in Mouse Models of Amelogenesis Imperfecta Caused by Amelx and Enam Mutations

Thomas Liam Coxon, Alan Henry Brook, Martin John Barron, Richard Nigel Smith

Cells Tissues Organs. 2012 Oct; 196(5): 420–430. Published online 2012 Jun 28. doi: 10.1159/000336440

PMCID:: PMC3718574

Abstract Article PDF–392K

Select item 277857810.

Consequences for enamel development and mineralization resulting from loss of function of ameloblastin or enamelin

Charles E. Smith, Rima Wazen, Yuanyuan Hu, Sylvia F. Zalzal, Antonio Nanci, James P. Simmer, Jan C-C. Hu

Eur J Oral Sci. Author manuscript; available in PMC 2009 Nov 17.

Published in final edited form as: Eur J Oral Sci. 2009 Oct; 117(5): 485–497. doi: 10.1111/j.1600-0722.2009.00666.x

PMCID:: PMC2778578

Abstract Article PDF–3.9M

Select item 244766911.

Enamel Defects and Ameloblast-specific Expression in Enam Knock-out/lacZ Knock-in Mice

Jan C.-C. Hu, Yuanyuan Hu, Charles E. Smith, Marc D. McKee, J. Timothy Wright, Yasuo Yamakoshi, Petros Papagerakis, Graeme K. Hunter, Jerry Q. Feng, Fumiko Yamakoshi, James P. Simmer

J Biol Chem. 2008 Apr 18; 283(16): 10858–10871. doi: 10.1074/jbc.M710565200

PMCID:: PMC2447669

Abstract Article PDF–1018K

Select item 229299312.

Epstein-Barr Virus Nuclear Antigen 1 Does Not Cause Lymphoma in C57BL/6J Mice

Myung-Soo Kang, Vishal Soni, Roderick Bronson, Elliott Kieff

J Virol. 2008 Apr; 82(8): 4180–4183. Published online 2008 Feb 6. doi: 10.1128/JVI.02596-07

PMCID:: PMC2292993

Abstract Article PDF–257K

Select item 329554613.

Relationships between protein and mineral during enamel development in normal and genetically altered mice

Charles E. Smith, Yuanyuan Hu, Amelia S. Richardson, John D. Bartlett, Jan C-C. Hu, James P. Simmer

Eur J Oral Sci. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Eur J Oral Sci. 2011 Dec; 119(Suppl 1): 125–135. doi: 10.1111/j.1600-0722.2011.00871.x

PMCID:: PMC3295546

Abstract Article PDF–5.4M

Select item 850039814.

Connexin 43-Mediated Gap Junction Communication Regulates Ameloblast Differentiation via ERK1/2 Phosphorylation

Aya Yamada, Keigo Yoshizaki, Masaki Ishikawa, Kan Saito, Yuta Chiba, Emiko Fukumoto, Ryoko Hino, Seira Hoshikawa, Mitsuki Chiba, Takashi Nakamura, Tsutomu Iwamoto, Satoshi Fukumoto

Front Physiol. 2021; 12: 748574. Published online 2021 Sep 24. doi: 10.3389/fphys.2021.748574

PMCID:: PMC8500398

Abstract Article PDF–2.8M

Select item 602374115.

The role of epithelial Stat3 in amelogenesis during mouse incisor renewal

Bin Zhang, Bo Meng, Edward Viloria, Adrien Naveau, Bernhard Ganss, Andrew H Jheon

Cells Tissues Organs. Author manuscript; available in PMC 2019 Mar 16.

Published in final edited form as: Cells Tissues Organs. 2018; 205(2): 63–71. Published online 2018 Mar 16. doi: 10.1159/000486745

PMCID:: PMC6023741

Abstract Article PDF–2.2M

Select item 481773016.

MEPE Localization in the Craniofacial Complex and Function in Tooth Dentin Formation

Angela Gullard, Jelica Gluhak-Heinrich, Silvana Papagerakis, Philip Sohn, Aaron Unterbrink, Shuo Chen, Mary MacDougall

J Histochem Cytochem. 2016 Apr; 64(4): 224–236. Published online 2016 Feb 29. doi: 10.1369/0022155416635569

PMCID:: PMC4817730

Abstract Article PDF–2.9M

Select item 363829317.

Dpysl4 Is Involved in Tooth Germ Morphogenesis through Growth Regulation, Polarization and Differentiation of Dental Epithelial Cells

Masato Yasukawa, Kentaro Ishida, Yohei Yuge, Mai Hanaoka, Yoko Minami, Miho Ogawa, Takashi Sasaki, Masahiro Saito, Takashi Tsuji

Int J Biol Sci. 2013; 9(4): 382–390. Published online 2013 Apr 26. doi: 10.7150/ijbs.5510

PMCID:: PMC3638293

Abstract Article PDF–988K

Select item 131698418.

periostin Null Mice Exhibit Dwarfism, Incisor Enamel Defects, and an Early-Onset Periodontal Disease-Like Phenotype

Hector Rios, Shrinagesh V. Koushik, Haiyan Wang, Jian Wang, Hong-Ming Zhou, Andrew Lindsley, Rhonda Rogers, Zhi Chen, Manabu Maeda, Agnieszka Kruzynska-Frejtag, Jian Q. Feng, Simon J. Conway

Mol Cell Biol. 2005 Dec; 25(24): 11131–11144. doi: 10.1128/MCB.25.24.11131-11144.2005

PMCID:: PMC1316984

Abstract Article PDF–1.8M

Select item 275486319.

Human and Mouse Enamel Phenotypes Resulting from Mutation or Altered Expression of AMEL, ENAM, MMP20 and KLK4

J. Timothy Wright, Thomas C. Hart, P. Suzanne Hart, Darrin Simmons, Cynthia Suggs, Bill Daley, Jim Simmer, Jan Hu, John D. Bartlett, Yong Li, Zhi-An Yuan, W. Kim Seow, Carolyn W. Gibson

Cells Tissues Organs. 2008 Dec; 189(1-4): 224–229. Published online 2008 Aug 19. doi: 10.1159/000151378