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Select item 107170131.

The distribution of eukaryotic initiation factor 4E after bouts of resistance exercise is altered by shortening of recovery periods

Junya Takegaki, Riki Ogasawara, Karina Kouzaki, Satoshi Fujita, Koichi Nakazato, Naokata Ishii

J Physiol Sci. 2020; 70: 54. Published online 2020 Nov 4. doi: 10.1186/s12576-020-00781-y

PMCID:: PMC10717013

Abstract Article PDF–1.6M

Select item 103503392.

The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity

Crystal S. Conn, Haojun Yang, Harrison J. Tom, Kenji Ikeda, Juan A. Oses-Prieto, Hieu Vu, Yasuo Oguri, Supna Nair, Ryan M. Gill, Shingo Kajimura, Ralph J. DeBerardinis, Alma L. Burlingame, Davide Ruggero

Nat Metab. Author manuscript; available in PMC 2023 Jul 16.

Published in final edited form as: Nat Metab. 2021 Feb; 3(2): 244–257. Published online 2021 Feb 18. doi: 10.1038/s42255-021-00349-z

PMCID:: PMC10350339

Abstract Article PDF–4.9M

Select item 78705683.

The role of cap-dependent translation in aged-related changes in neuroimmunity and affective behaviors

Prapti H. Mody, Natalia Lucia dos Santos, Melissa E. Lenert, Luz R. Barron, Bethany A. Nottingham, Michael D. Burton

Neurobiol Aging. Author manuscript; available in PMC 2022 Feb 1.

Published in final edited form as: Neurobiol Aging. 2021 Feb; 98: 173–184. Published online 2020 Nov 13. doi: 10.1016/j.neurobiolaging.2020.10.014

PMCID:: PMC7870568

Abstract Article PDF–1.1M

Select item 77329364.

eIF4E phosphorylation modulates pain and neuroinflammation in the aged

Prapti H. Mody, Natalia L. Dos Santos, Luz R. Barron, Theodore J. Price, Michael D. Burton

GeroScience. 2020 Dec; 42(6): 1663–1674. Published online 2020 Jul 1. doi: 10.1007/s11357-020-00220-1

PMCID:: PMC7732936

Abstract Article PDF–1.8M

Select item 69625215.

Phosphorylation of eukaryotic initiation factor 4E is dispensable for skeletal muscle hypertrophy

Vandre C. Figueiredo, Davis A. Englund, Ivan J. Vechetti, Jr., Alexander Alimov, Charlotte A. Peterson, John J. McCarthy

Am J Physiol Cell Physiol. 2019 Dec 1; 317(6): C1247–C1255. Published online 2019 Oct 9. doi: 10.1152/ajpcell.00380.2019

PMCID:: PMC6962521

Abstract Article

Select item 63249966.

The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes

Honyin Chiu, Leandra V. Jackson, Kwon Ik Oh, Annie Mai, Ze’ev A. Ronai, Davide Ruggero, David A. Fruman

J Immunol. Author manuscript; available in PMC 2020 Jan 15.

Published in final edited form as: J Immunol. 2019 Jan 15; 202(2): 579–590. Published online 2018 Dec 10. doi: 10.4049/jimmunol.1800602

PMCID:: PMC6324996

Abstract Article PDF–2.7M

Select item 58779857.

Translational control in the tumor microenvironment promotes lung metastasis: Phosphorylation of eIF4E in neutrophils

Nathaniel Robichaud, Brian E. Hsu, Roman Istomine, Fernando Alvarez, Julianna Blagih, Eric H. Ma, Sebastian V. Morales, David L. Dai, Glenn Li, Margarita Souleimanova, Qianyu Guo, Sonia V. del Rincon, Wilson H. Miller, Jr., Santiago Ramón y Cajal, Morag Park, Russell G. Jones, Ciriaco A. Piccirillo, Peter M. Siegel, Nahum Sonenberg

Proc Natl Acad Sci U S A. 2018 Mar 6; 115(10): E2202–E2209. Published online 2018 Feb 20. doi: 10.1073/pnas.1717439115

PMCID:: PMC5877985

Abstract Article PDF–1.5M

Select item 58247458.

Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation

Inês S. Amorim, Sonal Kedia, Stella Kouloulia, Konstanze Simbriger, Ilse Gantois, Seyed Mehdi Jafarnejad, Yupeng Li, Agniete Kampaite, Tine Pooters, Nicola Romanò, Christos G. Gkogkas

J Neurosci. 2018 Feb 21; 38(8): 2118–2133. doi: 10.1523/JNEUROSCI.2673-17.2018

PMCID:: PMC5824745

Abstract Article PDF–3.3M

Select item 49785459.

Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

Nathaniel Robichaud, Sonia V. del Rincon, Bonnie Huor, Tommy Alain, Andy Petruccelli, Jaclyn Hearnden, Christophe Goncalves, Stefan Grotegut, Charles H. Spruck, Luc Furic, Ola Larsson, Wilson H. Miller, Jr, Nahum Sonenberg

Oncogene. Author manuscript; available in PMC 2016 Aug 9.

Published in final edited form as: Oncogene. 2015 Apr 16; 34(16): 2032–2042. Published online 2014 Jun 9. doi: 10.1038/onc.2014.146

PMCID:: PMC4978545

Abstract Article PDF–1.2M

Select item 444615810.

Light-regulated translational control of circadian behavior by eIF4E phosphorylation

Ruifeng Cao, Christos G. Gkogkas, Nuria de Zavalia, Ian D. Blum, Akiko Yanagiya, Yoshinori Tsukumo, Haiyan Xu, Choogon Lee, Kai-Florian Storch, Andrew C. Liu, Shimon Amir, Nahum Sonenberg

Nat Neurosci. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Nat Neurosci. 2015 Jun; 18(6): 855–862. Published online 2015 Apr 27. doi: 10.1038/nn.4010

PMCID:: PMC4446158

Abstract Article PDF–2.1M

Select item 433521311.

Murine Norovirus 1 (MNV1) Replication Induces Translational Control of the Host by Regulating eIF4E Activity during Infection

Elizabeth Royall, Nicole Doyle, Azimah Abdul-Wahab, Ed Emmott, Simon J. Morley, Ian Goodfellow, Lisa O. Roberts, Nicolas Locker

J Biol Chem. 2015 Feb 20; 290(8): 4748–4758. Published online 2015 Jan 5. doi: 10.1074/jbc.M114.602649

PMCID:: PMC4335213

Abstract Article PDF–471K

Select item 334667612.

Targeting Synthetic Lethal Interactions between Myc and the eIF4F Complex Impedes Tumorigenesis

Chen-Ju Lin, Zeina Nasr, Prem K. Premsrirut, John A. Porco, Jr., Yoshitaka Hippo, Scott W. Lowe, Jerry Pelletier

Cell Rep. Author manuscript; available in PMC 2012 May 7.

Published in final edited form as: Cell Rep. 2012 Apr 19; 1(4): 325–333. Published online 2012 Mar. doi: 10.1016/j.celrep.2012.02.010

PMCID:: PMC3346676

Abstract Article PDF–1.5M

Select item 228728513.

The eIF4E RNA regulon promotes the Akt signaling pathway

Biljana Culjkovic, Keith Tan, Slobodanka Orolicki, Abdellatif Amri, Sylvain Meloche, Katherine L.B. Borden

J Cell Biol. 2008 Apr 7; 181(1): 51–63. doi: 10.1083/jcb.200707018

PMCID:: PMC2287285

Abstract Article PDF–2.5M

Select item 211302414.

Dissecting eIF4E action in tumorigenesis

Hans-Guido Wendel, Ricardo L.A. Silva, Abba Malina, John R. Mills, Hong Zhu, Takeshi Ueda, Rie Watanabe-Fukunaga, Rikiro Fukunaga, Julie Teruya-Feldstein, Jerry Pelletier, Scott. W. Lowe

Genes Dev. 2007 Dec 15; 21(24): 3232–3237. doi: 10.1101/gad.1604407

PMCID:: PMC2113024

Abstract Article PDF–558K

Select item 179741615.

Epigenetic Activation of a Subset of mRNAs by eIF4E Explains Its Effects on Cell Proliferation

Yaël Mamane, Emmanuel Petroulakis, Yvan Martineau, Taka-Aki Sato, Ola Larsson, Vinagolu K. Rajasekhar, Nahum Sonenberg

PLoS One. 2007; 2(2): e242. Published online 2007 Feb 21. doi: 10.1371/journal.pone.0000242

PMCID:: PMC1797416

Abstract Article PDF–553K

Select item 137069316.

High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation

KIYOTAKA MOCHIZUKI, AKIHIRO OGURO, TAKASHI OHTSU, NAHUM SONENBERG, YOSHIKAZU NAKAMURA

RNA. 2005 Jan; 11(1): 77–89. doi: 10.1261/rna.7108205

PMCID:: PMC1370693

Abstract Article PDF–512K

Select item 126573617.

Translation Initiation Factor 4E Inhibits Differentiation of Erythroid Progenitors

Montserrat Blázquez-Domingo, Godfrey Grech, Marieke von Lindern

Mol Cell Biol. 2005 Oct; 25(19): 8496–8506. doi: 10.1128/MCB.25.19.8496-8506.2005

PMCID:: PMC1265736

Abstract Article PDF–900K

Select item 4003118.

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

D Rousseau, R Kaspar, I Rosenwald, L Gehrke, N Sonenberg

Proc Natl Acad Sci U S A. 1996 Feb 6; 93(3): 1065–1070. doi: 10.1073/pnas.93.3.1065

PMCID:: PMC40031

Summary Page Browse PDF–1.6M

Select item 990540519.

miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice

Xiao Ke, Manfei Deng, Zhuoze Wu, Hongyan Yu, Dian Yu, Hao Li, Youming Lu, Kai Shu, Lei Pei

Neurosci Bull. 2023 Feb; 39(2): 194–212. Published online 2022 Jul 8. doi: 10.1007/s12264-022-00898-7

PMCID:: PMC9905405

Abstract Article PDF–7.5M

Select item 903378720.

Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy

Anirban Roy, Ashok Kumar

Nat Commun. 2022; 13: 2201. Published online 2022 Apr 22. doi: 10.1038/s41467-022-29752-0

PMCID:: PMC9033787

Abstract Article PDF–7.2M

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PMC Links for Gene (Select 13684) (113)
PMC
PREDICTED: Kryptolebias marmoratus metabolism of cobalamin associated Db (mmadhc...
PREDICTED: Kryptolebias marmoratus metabolism of cobalamin associated Db (mmadhcb), transcript variant X2, mRNA
gi|1938281695|ref|XM_037977593.1|

Nucleotide
serine/threonine-protein kinase LMTK1 isoform X2 [Gallus gallus]
serine/threonine-protein kinase LMTK1 isoform X2 [Gallus gallus]
gi|2024464471|ref|XP_040542465.1|

Protein
Serine/threonine-protein kinase LMTK1, partial [Eudyptes schlegeli]
Serine/threonine-protein kinase LMTK1, partial [Eudyptes schlegeli]
gi|1803617498|gb|KAF1558822.1||gnl| ULF|FQV10_0000371

Protein
R-75594
R-75594

biosample

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