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Select item 107975551.

A novel macrolide–Del-1 axis to regenerate bone in old age

Kridtapat Sirisereephap, Hikaru Tamura, Jong-Hyung Lim, Meircurius Dwi Condro Surboyo, Toshihito Isono, Takumi Hiyoshi, Andrea L. Rosenkranz, Yurie Sato-Yamada, Hisanori Domon, Akari Ikeda, Tomoyasu Hirose, Toshiaki Sunazuka, Nagako Yoshiba, Hiroyuki Okada, Yutaka Terao, Takeyasu Maeda, Koichi Tabeta, Triantafyllos Chavakis, George Hajishengallis, Tomoki Maekawa

iScience. 2024 Feb 16; 27(2): 108798. Published online 2024 Jan 4. doi: 10.1016/j.isci.2024.108798

PMCID:: PMC10797555

Abstract Article PDF–3.5M

Select item 95751072.

EDIL3 influenced the αvβ3‐FAK/MEK/ERK axis of endothelial cells in psoriasis

Xuping Niu, Qixin Han, Xinhua Li, Juan Li, Yanmin Liu, Yan Li, Yan Wu, Kaiming Zhang

J Cell Mol Med. 2022 Oct; 26(20): 5202–5212. Published online 2022 Sep 6. doi: 10.1111/jcmm.17544

PMCID:: PMC9575107

Abstract Article PDF–18M

Select item 89203413.

Developmental endothelial locus-1 protects from hypertension-induced cardiovascular remodeling via immunomodulation

Theresa Failer, Michael Amponsah-Offeh, Aleš Neuwirth, Ioannis Kourtzelis, Pallavi Subramanian, Peter Mirtschink, Mirko Peitzsch, Klaus Matschke, Sems M. Tugtekin, Tetsuhiro Kajikawa, Xiaofei Li, Anne Steglich, Florian Gembardt, Annika C. Wegner, Christian Hugo, George Hajishengallis, Triantafyllos Chavakis, Andreas Deussen, Vladimir Todorov, Irakli Kopaliani

J Clin Invest. 2022 Mar 15; 132(6): e126155. Published online 2022 Mar 15. doi: 10.1172/JCI126155

Correction in:: J Clin Invest. 2024 May 1; 134(9): e181599.

PMCID:: PMC8920341

Abstract Article PDF–8.3M

Select item 76580514.

Cell Cycle-Dependent ERK Signaling Dynamics Direct Fate Specification in the Mammalian Preimplantation Embryo

Michael J. Pokrass, Kathleen A. Ryan, Tianchi Xin, Brittany Pielstick, Winston Timp, Valentina Greco, Sergi Regot

Dev Cell. Author manuscript; available in PMC 2021 Nov 9.

Published in final edited form as: Dev Cell. 2020 Nov 9; 55(3): 328–340.e5. Published online 2020 Oct 21. doi: 10.1016/j.devcel.2020.09.013

PMCID:: PMC7658051

Abstract Article PDF–2.1M

Select item 72473085.

The secreted protein DEL-1 activates a β3 integrin–FAK–ERK1/2–RUNX2 pathway and promotes osteogenic differentiation and bone regeneration

Da-Yo Yuh, Tomoki Maekawa, Xiaofei Li, Tetsuhiro Kajikawa, Khalil Bdeir, Triantafyllos Chavakis, George Hajishengallis

J Biol Chem. 2020 May 22; 295(21): 7261–7273. Published online 2020 Apr 12. doi: 10.1074/jbc.RA120.013024

PMCID:: PMC7247308

Abstract Article PDF–3.0M

Select item 70267706.

DHEA Inhibits Leukocyte Recruitment through Regulation of the Integrin Antagonist DEL-1

Athanasios Ziogas, Tomoki Maekawa, Johannes R. Wiessner, Thi Trang Le, David Sprott, Maria Troullinaki, Ales Neuwirth, Vasiliki Anastasopoulou, Sylvia Grossklaus, Kyoung-Jin Chung, Markus Sperandio, Triantafyllos Chavakis, George Hajishengallis, Vasileia Ismini Alexaki

J Immunol. 2020 Mar 1; 204(5): 1214–1224. Published online 2020 Jan 24. doi: 10.4049/jimmunol.1900746

PMCID:: PMC7026770

Abstract Article PDF–944K

Select item 54195617.

An improved method with high sensitivity and low background in detecting low β-galactosidase expression in mouse embryos

Xiaopeng Shen, Wenjing Bao, Wei Yu, Rui Liang, Bao Nguyen, Yu Liu

PLoS One. 2017; 12(5): e0176915. Published online 2017 May 5. doi: 10.1371/journal.pone.0176915

PMCID:: PMC5419561

Abstract Article PDF–14M

Select item 46709868.

Development of the anterior-posterior axis is a self-organizing process in the absence of maternal cues in the mouse embryo

Ivan Bedzhov, Monika Bialecka, Agata Zielinska, Joanna Kosalka, Francesco Antonica, Amelia J Thompson, Kristian Franze, Magdalena Zernicka-Goetz

Cell Res. 2015 Dec; 25(12): 1368–1371. Published online 2015 Sep 4. doi: 10.1038/cr.2015.104

PMCID:: PMC4670986

Article PDF–1.9M

Select item 31932539.

Regulatory elements required for the activation and repression of the protocadherin-α gene cluster

Polina Kehayova, Kevin Monahan, Weisheng Chen, Tom Maniatis

Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41): 17195–17200. Published online 2011 Sep 26. doi: 10.1073/pnas.1114357108

PMCID:: PMC3193253

Abstract Article PDF–605K

Select item 255375710.

Del-1 Gene Transfer Induces Cerebral Angiogenesis in Mice

Yongfeng Fan, Wei Zhu, Michael Yang, Yiqian Zhu, Fanxia Shen, Qi Hao, William L. Young, Guo-Yuan Yang, Yongmei Chen

Brain Res. Author manuscript; available in PMC 2009 Jul 11.

Published in final edited form as: Brain Res. 2008 Jul 11; 1219: 1–7. Published online 2008 May 10. doi: 10.1016/j.brainres.2008.05.003

PMCID:: PMC2553757

Abstract Article PDF–1.2M

Select item 1119203711.

Influence of the Calcium Voltage-Gated Channel Auxiliary Subunit (CACNA2D1) Absence on Intraocular Pressure in Mice

Levi Lankford, Rupalatha Maddala, Monica M. Jablonski, P. Vasantha Rao

Exp Eye Res. Author manuscript; available in PMC 2024 Jun 21.

Published in final edited form as: Exp Eye Res. 2024 Apr; 241: 109835. Published online 2024 Feb 17. doi: 10.1016/j.exer.2024.109835

PMCID:: PMC11192037

Abstract Article PDF–2.1M

Select item 1117980212.

Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension

Alejandra Becerra Calderon, Urvi Nikhil Shroff, Sachin Deepak, Audrey Izuhara, Greta Trogen, Alicia A. McDonough, Susan B. Gurley, Jonathan W. Nelson, János Peti‐Peterdi, Georgina Gyarmati

J Am Heart Assoc. 2024 May 21; 13(10): e033998. Published online 2024 May 10. doi: 10.1161/JAHA.123.033998

PMCID:: PMC11179802

Abstract Article PDF–24M

Select item 1110056813.

Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease

Guogang Xu, Songhua Quan, Joseph Schell, Yucheng Gao, Mahboubeh Varmazyad, Prethish Sreenivas, Diego Cruz, Haiyan Jiang, Meixia Pan, Xianlin Han, Juan Pablo Palavicini, Peng Zhao, Xiaoli Sun, Erik D. Marchant, Blake B. Rasmussen, Guannan Li, Sakie Katsumura, Masahiro Morita, Erin Munkácsy, Nobuo Horikoshi, E. Sandra Chocron, David Gius

Sci Adv. 2024 May 17; 10(20): eadj5942. Published online 2024 May 17. doi: 10.1126/sciadv.adj5942

PMCID:: PMC11100568

Abstract Article PDF–3.4M

Select item 1101826714.

Obesity and altered angiogenic-related gene expression in endometrial cancer

Lauren Patterson Cobb, Sharareh Siamakpour-Reihani, Dadong Zhang, Xiaodi Qin, Kouros Owzar, Chunxiao Zhou, Thomas P. Conrads, G. Larry Maxwell, Kathleen M. Darcy, Nicholas Bateman, Tracy Litzi, Victoria Bae-Jump, Angeles Alvarez Secord

Gynecol Oncol. Author manuscript; available in PMC 2024 Apr 15.

Published in final edited form as: Gynecol Oncol. 2021 Nov; 163(2): 320–326. Published online 2021 Sep 15. doi: 10.1016/j.ygyno.2021.08.010

PMCID:: PMC11018267

Abstract Article PDF–758K

Select item 1088811715.

Del-1 Plays a Protective Role against COPD Development by Inhibiting Inflammation and Apoptosis

Nakwon Kwak, Kyoung-Hee Lee, Jisu Woo, Jiyeon Kim, Jimyung Park, Chang-Hoon Lee, Chul-Gyu Yoo

Int J Mol Sci. 2024 Feb; 25(4): 1955. Published online 2024 Feb 6. doi: 10.3390/ijms25041955

PMCID:: PMC10888117

Abstract Article PDF–4.2M

Select item 1087741016.

BRCA1 protein dose-dependent risk for embryonic oxidative DNA damage, embryopathies and neurodevelopmental disorders with and without ethanol exposure

Danielle M. Drake, Kian Afsharian, Benjamin Or, Aaron M. Shapiro, Michelle L. Lai, Lutfiya Miller, Peter G. Wells

Redox Biol. 2024 Apr; 70: 103070. Published online 2024 Feb 8. doi: 10.1016/j.redox.2024.103070

PMCID:: PMC10877410

Abstract Article PDF–5.5M

Select item 1052070917.

SPAG17 mediates nuclear translocation of protamines during spermiogenesis

Clara Agudo-Rios, Amber Rogers, Isaiah King, Virali Bhagat, Le My Tu Nguyen, Carlos Córdova-Fletes, Diego Krapf, Jerome F. Strauss, III, Lena Arévalo, Gina Esther Merges, Hubert Schorle, Eduardo R. S. Roldan, Maria Eugenia Teves

Front Cell Dev Biol. 2023; 11: 1125096. Published online 2023 Sep 12. doi: 10.3389/fcell.2023.1125096

PMCID:: PMC10520709

Abstract Article PDF–1.9M

Select item 1045242018.

Del1 Is a Growth Factor for Skeletal Progenitor Cells in the Fracture Callus

Yuxi Sun, Tatiana Boyko, Owen Marecic, Danielle Struck, Randall K. Mann, Tom W. Andrew, Michael Lopez, Xinming Tong, Stuart B. Goodman, Fan Yang, Michael T. Longaker, Charles K. F. Chan, George P. Yang

Biomolecules. 2023 Aug; 13(8): 1214. Published online 2023 Aug 3. doi: 10.3390/biom13081214

PMCID:: PMC10452420

Abstract Article PDF–35M

Select item 1035814719.

Androgen Resistance in Female Mice Increases Susceptibility to DMBA-Induced Mammary Tumors

Ulla Simanainen, Yan Ru Gao, Kirsty A. Walters, Geoff Watson, Reena Desai, Mark Jimenez, David J. Handelsman

Horm Cancer. 2012 Jun; 3(3): 113–124. Published online 2012 Feb 28. doi: 10.1007/s12672-012-0107-9

PMCID:: PMC10358147

Abstract Article PDF–703K

Select item 1029891820.

Epidermal Loss of RORα Enhances Skin Inflammation in a MC903-Induced Mouse Model of Atopic Dermatitis

Xiangmei Hua, Conrad Dean Blosch, Hannah Dorsey, Maria K. Ficaro, Nicole L. Wallace, Richard P. Hsung, Jun Dai

Int J Mol Sci. 2023 Jun; 24(12): 10241. Published online 2023 Jun 16. doi: 10.3390/ijms241210241

PMCID:: PMC10298918

Abstract Article PDF–6.0M

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