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Select item 111582201.

Up‐regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity

Sumitaka Hagiwara, Yoshiki Murakumo, Tomoko Sato, Toshio Shigetomi, Kenji Mitsudo, Iwai Tohnai, Minoru Ueda, Masahide Takahashi

Cancer Sci. 2008 Oct; 99(10): 1916–1923. Published online 2008 Oct 3. doi: 10.1111/j.1349-7006.2008.00949.x

PMCID:: PMC11158220

Abstract Article PDF–437K

Select item 102996492.

CD109 Promotes Drug Resistance in A2780 Ovarian Cancer Cells by Regulating the STAT3-NOTCH1 Signaling Axis

Jun Se Kim, Min Joo Shin, Seo Yul Lee, Dae Kyoung Kim, Kyung-Un Choi, Dong-Soo Suh, Dayea Kim, Jae Ho Kim

Int J Mol Sci. 2023 Jun; 24(12): 10306. Published online 2023 Jun 18. doi: 10.3390/ijms241210306

PMCID:: PMC10299649

Abstract Article PDF–3.2M

Select item 79260253.

Serum CD109 levels reflect the node metastasis status in head and neck squamous cell carcinoma

Sumitaka Hagiwara, Eiichi Sasaki, Yasuhisa Hasegawa, Hidenori Suzuki, Daisuke Nishikawa, Shintaro Beppu, Hoshino Terada, Michi Sawabe, Masahide Takahashi, Nobuhiro Hanai

Cancer Med. 2021 Feb; 10(4): 1335–1346. Published online 2021 Feb 9. doi: 10.1002/cam4.3737

PMCID:: PMC7926025

Abstract Article PDF–1.0M

Select item 78232734.

Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling

Kang-Yun Lee, Tai-Chih Kuo, Chih-Ming Chou, Wen-Jing Hsu, Wei-Cheng Lee, Jia-Zih Dai, Sheng-Ming Wu, Cheng-Wei Lin

Cells. 2021 Jan; 10(1): 28. Published online 2020 Dec 25. doi: 10.3390/cells10010028

PMCID:: PMC7823273

Abstract Article PDF–2.4M

Select item 72261825.

Elevation of CD109 promotes metastasis and drug resistance in lung cancer via activation of EGFR‐AKT‐mTOR signaling

Kang‐Yun Lee, Pei‐Wei Shueng, Chih‐Ming Chou, Bo‐Xing Lin, Mei‐Hsiang Lin, Deng‐Yu Kuo, I‐Lin Tsai, Sheng‐Ming Wu, Cheng‐Wei Lin

Cancer Sci. 2020 May; 111(5): 1652–1662. Published online 2020 Mar 25. doi: 10.1111/cas.14373

PMCID:: PMC7226182

Abstract Article PDF–2.0M

Select item 68345706.

CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro

Shufeng Zhou, Sabrina Daniela da Silva, Peter M. Siegel, Anie Philip

Sci Rep. 2019; 9: 16317. Published online 2019 Nov 6. doi: 10.1038/s41598-019-50694-z

PMCID:: PMC6834570

Abstract Article PDF–18M

Select item 45458197.

CD109 is a novel marker for squamous cell/adenosquamous carcinomas of the gallbladder

Fengyun Dong, Chuanfeng Lu, Xiaocui Chen, Yuan Guo, Ju Liu

Diagn Pathol. 2015; 10: 137. Published online 2015 Aug 7. doi: 10.1186/s13000-015-0375-0

PMCID:: PMC4545819

Abstract Article PDF–989K

Select item 42666088.

A Subpopulation of Circulating Endothelial Cells Express CD109 and is Enriched in the Blood of Cancer Patients

Patrizia Mancuso, Angelica Calleri, Giuliana Gregato, Valentina Labanca, Jessica Quarna, Pierluigi Antoniotti, Lucia Cuppini, Gaetano Finocchiaro, Marica Eoli, Vittorio Rosti, Francesco Bertolini

PLoS One. 2014; 9(12): e114713. Published online 2014 Dec 15. doi: 10.1371/journal.pone.0114713

PMCID:: PMC4266608

Abstract Article PDF–1.0M

Select item 38698409.

High Expression of CD109 Antigen Regulates the Phenotype of Cancer Stem-Like Cells/Cancer-Initiating Cells in the Novel Epithelioid Sarcoma Cell Line ESX and Is Related to Poor Prognosis of Soft Tissue Sarcoma

Makoto Emori, Tomohide Tsukahara, Masaki Murase, Masanobu Kano, Kenji Murata, Akari Takahashi, Terufumi Kubo, Hiroko Asanuma, Kazuyo Yasuda, Vitaly Kochin, Mitsunori Kaya, Satoshi Nagoya, Jun Nishio, Hiroshi Iwasaki, Tomoko Sonoda, Tadashi Hasegawa, Toshihiko Torigoe, Takuro Wada, Toshihiko Yamashita, Noriyuki Sato

PLoS One. 2013; 8(12): e84187. Published online 2013 Dec 20. doi: 10.1371/journal.pone.0084187

PMCID:: PMC3869840

Abstract Article PDF–3.5M

Select item 358308810.

Human Platelet Antigen Genotyping and Expression of CD109 (Human Platelet Antigen 15) mRNA in Various Human Cell Types

Sang Mee Hwang, Mi Jung Kim, Ho Eun Chang, Yun Ji Hong, Taek Soo Kim, Eun Young Song, Kyoung Un Park, Junghan Song, Kyou-Sup Han

Biomed Res Int. 2013; 2013: 946403. Published online 2013 Feb 12. doi: 10.1155/2013/946403

PMCID:: PMC3583088

Abstract Article PDF–507K

Select item 826234211.

CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity

Pauliina Filppu, Jayendrakishore Tanjore Ramanathan, Kirsi J. Granberg, Erika Gucciardo, Hannu Haapasalo, Kaisa Lehti, Matti Nykter, Vadim Le Joncour, Pirjo Laakkonen

JCI Insight. 2021 May 10; 6(9): e141486. Published online 2021 May 10. doi: 10.1172/jci.insight.141486

PMCID:: PMC8262342

Abstract Article PDF–16M

Select item 749491312.

Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy

Soniya Bastola, Marat S. Pavlyukov, Daisuke Yamashita, Sadashib Ghosh, Heejin Cho, Noritaka Kagaya, Zhuo Zhang, Mutsuko Minata, Yeri Lee, Hirokazu Sadahiro, Shinobu Yamaguchi, Svetlana Komarova, Eddy Yang, James Markert, Louis B. Nabors, Krishna Bhat, James Lee, Qin Chen, David K. Crossman, Kazuo Shin-Ya, Do-Hyun Nam, Ichiro Nakano

Nat Commun. 2020; 11: 4660. Published online 2020 Sep 16. doi: 10.1038/s41467-020-18189-y

PMCID:: PMC7494913

Abstract Article PDF–7.4M

Select item 504539913.

Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma

Bo-Gen Ye, Hui-Chuan Sun, Xiao-Dong Zhu, Zong-Tao Chai, Yuan-Yuan Zhang, Jian-Yang Ao, Hao Cai, De-Ning Ma, Cheng-Hao Wang, Cheng-Dong Qin, Dong-Mei Gao, Zhao-You Tang

Oncotarget. 2016 May 17; 7(20): 29333–29345. Published online 2016 Apr 18. doi: 10.18632/oncotarget.8787

PMCID:: PMC5045399

Abstract Article PDF–15M

Select item 388099314.

Human Hepatic Progenitor Cells Express Hematopoietic Cell Markers CD45 and CD109

Jun Li, Jiaojiao Xin, Liyuan Zhang, Jian Wu, Longyan Jiang, Qian Zhou, Jun Li, Jing Guo, Hongcui Cao, Lanjuan Li

Int J Med Sci. 2014; 11(1): 65–79. Published online 2013 Dec 21. doi: 10.7150/ijms.7426

PMCID:: PMC3880993

Abstract Article PDF–2.3M

Select item 344652715.

CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts

Xiao-Yong Man, Kenneth W Finnson, Murray Baron, Anie Philip

Arthritis Res Ther. 2012; 14(3): R144. Published online 2012 Jun 13. doi: 10.1186/ar3877

PMCID:: PMC3446527

Abstract Article PDF–565K

Select item 292929316.

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

Alexandra Hockla, Derek C. Radisky, Evette S. Radisky

Breast Cancer Res Treat. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Breast Cancer Res Treat. 2010 Nov; 124(1): 27–38. Published online 2009 Dec 25. doi: 10.1007/s10549-009-0699-0

PMCID:: PMC2929293

Abstract Article PDF–2.8M

Select item 746300317.

CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma

Xue-Tang Mo, Thomas Ho-Yin Leung, Hermit Wai-Man Tang, Michelle Kwan-Yee Siu, Peter Kok-Ting Wan, Karen Kar-Loen Chan, Annie Nga-Yin Cheung, Hextan Yuen-Sheung Ngan

Br J Cancer. 2020 Sep 1; 123(5): 833–843. Published online 2020 Jun 8. doi: 10.1038/s41416-020-0922-7

PMCID:: PMC7463003

Abstract Article PDF–3.8M

Select item 593906318.

Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-β signaling

Yuan-Li Tsai, Dat P. Ha, He Zhao, Anthony J. Carlos, Shan Wei, Tsam Kiu Pun, Kaijin Wu, Ebrahim Zandi, Kevin Kelly, Amy S. Lee

Proc Natl Acad Sci U S A. 2018 May 1; 115(18): E4245–E4254. Published online 2018 Apr 13. doi: 10.1073/pnas.1714866115

PMCID:: PMC5939063

Abstract Article PDF–2.4M

Select item 640211619.

Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma

Rui Peng, Peng-Fei Zhang, Xuan Yang, Chuan-Yuan Wei, Xiao-Yong Huang, Jia-Bin Cai, Jia-Cheng Lu, Chao Gao, Hai-Xiang Sun, Qiang Gao, Dou-Sheng Bai, Guo-Ming Shi, Ai-Wu Ke, Jia Fan

J Exp Clin Cancer Res. 2019; 38: 113. Published online 2019 Mar 5. doi: 10.1186/s13046-019-1113-3

PMCID:: PMC6402116

Abstract Article PDF–3.0M

Select item 377800420.

Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations

Conall M. O'Seaghdha, Hongsheng Wu, Qiong Yang, Karen Kapur, Idris Guessous, Annie Mercier Zuber, Anna Köttgen, Candice Stoudmann, Alexander Teumer, Zoltán Kutalik, Massimo Mangino, Abbas Dehghan, Weihua Zhang, Gudny Eiriksdottir, Guo Li, Toshiko Tanaka, Laura Portas, Lorna M. Lopez, Caroline Hayward, Kurt Lohman, Koichi Matsuda, Sandosh Padmanabhan, Dmitri Firsov, Rossella Sorice, Sheila Ulivi, A. Catharina Brockhaus, Marcus E. Kleber, Anubha Mahajan, Florian D. Ernst, Vilmundur Gudnason, Lenore J. Launer, Aurelien Mace, Eric Boerwinckle, Dan E. Arking, Chizu Tanikawa, Yusuke Nakamura, Morris J. Brown, Jean-Michel Gaspoz, Jean-Marc Theler, David S. Siscovick, Bruce M. Psaty, Sven Bergmann, Peter Vollenweider, Veronique Vitart, Alan F. Wright, Tatijana Zemunik, Mladen Boban, Ivana Kolcic, Pau Navarro, Edward M. Brown, Karol Estrada, Jingzhong Ding, Tamara B. Harris, Stefania Bandinelli, Dena Hernandez, Andrew B. Singleton, Giorgia Girotto, Daniela Ruggiero, Adamo Pio d'Adamo, Antonietta Robino, Thomas Meitinger, Christa Meisinger, Gail Davies, John M. Starr, John C. Chambers, Bernhard O. Boehm, Bernhard R. Winkelmann, Jie Huang, Federico Murgia, Sarah H. Wild, Harry Campbell, Andrew P. Morris, Oscar H. Franco, Albert Hofman, Andre G. Uitterlinden, Fernando Rivadeneira, Uwe Völker, Anke Hannemann, Reiner Biffar, Wolfgang Hoffmann, So–Youn Shin, Pierre Lescuyer, Hughes Henry, Claudia Schurmann, The SUNLIGHT consortium, The GEFOS consortium, Patricia B. Munroe, Paolo Gasparini, Nicola Pirastu, Marina Ciullo, Christian Gieger, Winfried März, Lars Lind, Tim D. Spector, Albert V. Smith, Igor Rudan, James F. Wilson, Ozren Polasek, Ian J. Deary, Mario Pirastu, Luigi Ferrucci, Yongmei Liu, Bryan Kestenbaum, Jaspal S. Kooner, Jacqueline C. M. Witteman, Matthias Nauck, W. H. Linda Kao, Henri Wallaschofski, Olivier Bonny, Caroline S. Fox, Murielle Bochud

PLoS Genet. 2013 Sep; 9(9): e1003796. Published online 2013 Sep 19. doi: 10.1371/journal.pgen.1003796

PMCID:: PMC3778004

Abstract Article PDF–797K

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