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Select item 109585851.

Human Genetic Variation at rs10071329 Correlates With Adiposity-Related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Mi Huang, Rashmi B. Prasad, Daniel E. Coral, Line Hjort, Daniel T.R. Minja, Hindrik Mulder, Paul W. Franks, Sebastian Kalamajski

Diabetes. 2024 Apr; 73(4): 637–645. Published online 2024 Jan 8. doi: 10.2337/db23-0531

PMCID:: PMC10958585

Abstract Article PDF–70M

Select item 83851102.

Decreased PGC1β expression results in disrupted human erythroid differentiation, impaired hemoglobinization and cell cycle exit

Taha Sen, Jun Chen, Sofie Singbrant

Sci Rep. 2021; 11: 17129. Published online 2021 Aug 24. doi: 10.1038/s41598-021-96585-0

PMCID:: PMC8385110

Abstract Article PDF–3.2M

Select item 64921243.

Reduced cardiomyocyte Na⁺ current in the age‐dependent murine Pgc‐1β^−/− model of ventricular arrhythmia

Shiraz Ahmad, Haseeb Valli, Robert Smyth, Anita Y. Jiang, Kamalan Jeevaratnam, Hugh R. Matthews, Christopher L.‐H. Huang

J Cell Physiol. 2019 Apr; 234(4): 3921–3932. Published online 2018 Aug 26. doi: 10.1002/jcp.27183

PMCID:: PMC6492124

Abstract Article PDF–978K

Select item 61202524.

PGC1β regulates multiple myeloma tumor growth through LDHA‐mediated glycolytic metabolism

Hongyu Zhang, Ling Li, Qi Chen, Min Li, Jia Feng, Ying Sun, Rong Zhao, Yin Zhu, Yang Lv, Zhigang Zhu, Xiaodong Huang, Weiguo Xie, Wei Xiang, Paul Yao

Mol Oncol. 2018 Sep; 12(9): 1579–1595. Published online 2018 Aug 14. doi: 10.1002/1878-0261.12363

PMCID:: PMC6120252

Abstract Article PDF–1.2M

Select item 60028815.

PGC1β Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation

Yan Zhang, Nidhi Rohatgi, Deborah J. Veis, Joel Schilling, Steven L. Teitelbaum, Wei Zou

J Bone Miner Res. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: J Bone Miner Res. 2018 Jun; 33(6): 1114–1125. Published online 2018 Mar 11. doi: 10.1002/jbmr.3398

PMCID:: PMC6002881

Abstract Article PDF–1.8M

Select item 58429206.

A PGC1β genetic variant associated with nevus count and melanoma mortality

Xin Li, Hongliang Liu, Christopher I. Amos, Jeffrey E. Lee, Nancy E. Thomas, Qingyi Wei, Jiali Han

Int J Cancer. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: Int J Cancer. 2017 Sep 1; 141(5): 1066–1067. Published online 2017 Jun 8. doi: 10.1002/ijc.30802

PMCID:: PMC5842920

Article PDF–284K

Select item 57257127.

Pro‐arrhythmic atrial phenotypes in incrementally paced murine Pgc1β^−/− hearts: effects of age

Haseeb Valli, Shiraz Ahmad, James A. Fraser, Kamalan Jeevaratnam, Christopher L.‐H. Huang

Exp Physiol. 2017 Dec 1; 102(12): 1619–1634. Published online 2017 Oct 29. doi: 10.1113/EP086589

PMCID:: PMC5725712

Abstract Article PDF–1.1M

Select item 39364688.

Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes

Raquel Villegas, Scott M. Williams, Yu-Tang Gao, Jirong Long, Jiajun Shi, Hui Cai, Honglan Li, Ching-Chu Chen, E. Shyong Tai, AGEN-T2D Consortium, Frank Hu, Qiuyin Cai, Wei Zheng, Xiao-Ou Shu

Ann Hum Genet. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Ann Hum Genet. 2014 Jan; 78(1): 23–32. doi: 10.1111/ahg.12044

PMCID:: PMC3936468

Abstract Article PDF–109K

Select item 31095789.

Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer

Yuqing Li, Yi Li, Sara Wedrén, Guoliang Li, Tze Howe Charn, Kartiki Vasant Desai, Carine Bonnard, Kamila Czene, Keith Humphreys, Hatef Darabi, Kristjana Einarsdóttir, Tuomas Heikkinen, Kristiina Aittomäki, Carl Blomqvist, Kee Seng Chia, Heli Nevanlinna, Per Hall, Edison T Liu, Jianjun Liu

Breast Cancer Res. 2011; 13(1): R10. Published online 2011 Jan 26. doi: 10.1186/bcr2817

PMCID:: PMC3109578

Abstract Article PDF–359K

Select item 304220810.

Phosphatidylinositol 3-kinase affects mitochondrial function in part through inducing peroxisome proliferator-activated receptor γ coactivator-1β expression

Minghui Gao, Junjian Wang, Wenxian Wang, Jinsong Liu, Chi-Wai Wong

Br J Pharmacol. 2011 Feb; 162(4): 1000–1008. doi: 10.1111/j.1476-5381.2010.01105.x

PMCID:: PMC3042208

Abstract Article PDF–703K

Select item 52574111.

Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

Charlotte Ling, Pernille Poulsen, Emma Carlsson, Martin Ridderstråle, Peter Almgren, Jørgen Wojtaszewski, Henning Beck-Nielsen, Leif Groop, Allan Vaag

J Clin Invest. 2004 Nov 15; 114(10): 1518–1526. doi: 10.1172/JCI21889

PMCID:: PMC525741

Abstract Article PDF–547K

Select item 992651412.

LMP1 mediates tumorigenesis through persistent epigenetic modifications and PGC1β upregulation

Siliang Chen, Ping Zhang, Jia Feng, Rui Li, Junhui Chen, Wei V. Zheng, Hongyu Zhang, Paul Yao

Oncol Rep. 2023 Mar; 49(3): 53. Published online 2023 Feb 2. doi: 10.3892/or.2023.8490

PMCID:: PMC9926514

Abstract Article PDF–3.7M

Select item 974187913.

Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia

Tamizh Paavai Thamizhanambi, Annasamy Rameshkumar, Ramadoss Ramya, Rajkumar Krishnan, Thayalan Dineshkumar, Gunasekaran Nandhini

Asian Pac J Cancer Prev. 2022 Aug; 23(8): 2797–2803. doi: 10.31557/APJCP.2022.23.8.2797

PMCID:: PMC9741879

Abstract Article PDF–332K

Select item 935971614.

PGC1α/β Expression Predicts Therapeutic Response to Oxidative Phosphorylation Inhibition in Ovarian Cancer

Carmen Ghilardi, Catarina Moreira-Barbosa, Laura Brunelli, Paola Ostano, Nicolò Panini, Monica Lupi, Alessia Anastasia, Fabio Fiordaliso, Monica Salio, Laura Formenti, Massimo Russo, Edoardo Arrigoni, Ferdinando Chiaradonna, Giovanna Chiorino, Giulio Draetta, Joseph R. Marszalek, Christopher P. Vellano, Roberta Pastorelli, MariaRosa Bani, Alessandra Decio, Raffaella Giavazzi

Cancer Res. 2022 Apr 1; 82(7): 1423–1434. Published online 2022 Feb 7. doi: 10.1158/0008-5472.CAN-21-1223

PMCID:: PMC9359716

Abstract Article PDF–1.4M

Select item 812912615.

UBQLN1 mediates sorafenib resistance through regulating mitochondrial biogenesis and ROS homeostasis by targeting PGC1β in hepatocellular carcinoma

Junjie Xu, Lin Ji, Yeling Ruan, Zhe Wan, Zhongjie Lin, Shunjie Xia, Liye Tao, Junhao Zheng, Liuxin Cai, Yifan Wang, Xiao Liang, Xiujun Cai

Signal Transduct Target Ther. 2021; 6: 190. Published online 2021 May 18. doi: 10.1038/s41392-021-00594-4

PMCID:: PMC8129126

Abstract Article PDF–7.4M

Select item 683147016.

Yin Yang 1 facilitates hepatocellular carcinoma cell lipid metabolism and tumor progression by inhibiting PGC-1β-induced fatty acid oxidation

Yanjun Li, Vivi Kasim, Xuesong Yan, Lang Li, Ian Timothy Sembiring Meliala, Can Huang, Zhuolin Li, Ke Lei, Guanbin Song, Xiaodong Zheng, Shourong Wu

Theranostics. 2019; 9(25): 7599–7615. Published online 2019 Oct 14. doi: 10.7150/thno.34931

PMCID:: PMC6831470

Abstract Article PDF–3.6M

Select item 636771317.

Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort

Jacob K Kresovich, Brian T Joyce, Tao Gao, Yinan Zheng, Zhou Zhang, Christopher J Achenbach, Robert L Murphy, Allan C Just, Jincheng Shen, Hushan Yang, Pantel Vokonas, Joel Schwartz, Andrea A Baccarelli, Lifang Hou

Epigenomics. 2018 Jun; 10(6): 733–742. Published online 2018 Jun 11. doi: 10.2217/epi-2017-0141

PMCID:: PMC6367713

Abstract Article PDF–1013K

Select item 628960318.

Peroxisome proliferator-activated receptor γ coactivator family members competitively regulate hepatitis b virus biosynthesis

Rasha E. Shalaby, Saira Iram, Claudia E. Oropeza, Alan McLachlan

Virology. Author manuscript; available in PMC 2020 Jan 2.

Published in final edited form as: Virology. 2019 Jan 2; 526: 214–221. Published online 2018 Nov 10. doi: 10.1016/j.virol.2018.10.027

PMCID:: PMC6289603

Abstract Article PDF–1.1M

Select item 581379319.

Genetic Variants in PPARGC1B and CNTN4 are Associated with Thromboxane A₂ Formation and with Cardiovascular Event Free Survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)

NS McCarthy, C Vangjeli, P Surendran, A Treumann, C Rooney, E Ho, P Sever, S Thom, AD Hughes, PB Munroe, P Howard, T Johnson, M Caulfield, DC Shields, E O’Brien, DJ Fitzgerald, AV Stanton

Atherosclerosis. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Atherosclerosis. 2018 Feb; 269: 42–49. Published online 2017 Dec 8. doi: 10.1016/j.atherosclerosis.2017.12.013

PMCID:: PMC5813793

Abstract Article PDF–1023K

Select item 549176820.

The FOXO3/PGC-1β signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma

Motofumi Kumazoe, Mika Takai, Shun Hiroi, Chieri Takeuchi, Mai Kadomatsu, Takashi Nojiri, Hiroaki Onda, Jaehoon Bae, Yuhui Huang, Kanako Takamatsu, Shuya Yamashita, Kenji Kangawa, Hirofumi Tachibana

J Biol Chem. 2017 Jun 30; 292(26): 10813–10823. Published online 2017 May 15. doi: 10.1074/jbc.M116.772111

PMCID:: PMC5491768

Abstract Article PDF–3.2M

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