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Select item 109316051.

Deletion of Gadd45a Expression in Mice Leads to Cognitive and Synaptic Impairment Associated with Alzheimer’s Disease Hallmarks

Christian Griñán-Ferré, Júlia Jarne-Ferrer, Aina Bellver-Sanchis, Marta Ribalta-Vilella, Emma Barroso, Jesús M. Salvador, Javier Jurado-Aguilar, Xavier Palomer, Manuel Vázquez-Carrera, Mercè Pallàs

Int J Mol Sci. 2024 Mar; 25(5): 2595. Published online 2024 Feb 23. doi: 10.3390/ijms25052595

PMCID:: PMC10931605

Abstract Article PDF–3.7M

Select item 105614322.

GADD45A regulates subcutaneous fat deposition and lipid metabolism by interacting with Stat1

Wenjing You, Shiqi Liu, Jie Li, Yuang Tu, Tizhong Shan

BMC Biol. 2023; 21: 212. Published online 2023 Oct 9. doi: 10.1186/s12915-023-01713-z

PMCID:: PMC10561432

Abstract Article PDF–4.2M

Select item 105594523.

Impact of GADD45A on radiation biodosimetry using mouse peripheral blood

Constantinos G. Broustas, Sanjay Mukherjee, Igor Shuryak, Alexandra Taraboletti, Jerry Angdisen, Pelagie Ake, Albert J. Fornace, Jr., Sally A. Amundson

Radiat Res. Author manuscript; available in PMC 2023 Oct 7.

Published in final edited form as: Radiat Res. 2023 Sep 1; 200(3): 296–306. doi: 10.1667/RADE-23-00052.1

PMCID:: PMC10559452

Abstract Article PDF–768K

Select item 84100744.

GADD45A is a protective modifier of neurogenic skeletal muscle atrophy

Jeffrey T. Ehmsen, Riki Kawaguchi, Damlanur Kaval, Anna E. Johnson, Daniel Nachun, Giovanni Coppola, Ahmet Höke

JCI Insight. 2021 Jul 8; 6(13): e149381. Published online 2021 Jul 8. doi: 10.1172/jci.insight.149381

PMCID:: PMC8410074

Abstract Article PDF–14M

Select item 65490225.

Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNAs

Alejandro Aparisi Rey, Emil Karaulanov, Salim Sharopov, Khelifa Arab, Andrea Schäfer, Mathias Gierl, Stephan Guggenhuber, Caroline Brandes, Luigi Pennella, Wolfram H Gruhn, Ruth Jelinek, Christina Maul, Andrea Conrad, Werner Kilb, Heiko J Luhmann, Christof Niehrs, Beat Lutz

EMBO Rep. 2019 Jun; 20(6): e46022. Published online 2019 Apr 4. doi: 10.15252/embr.201846022

PMCID:: PMC6549022

Abstract Article PDF–2.5M

Select item 58427926.

Conserved DNA methylation in Gadd45a^-/- mice

Nora Engel, Jennifer S. Tront, Toyin Erinle, Nghi Nguyen, Keith E. Latham, Carmen Sapienza, Barbara Hoffman, Dan A. Liebermann

Epigenetics. Author manuscript; available in PMC 2018 Mar 8.

Published in final edited form as: Epigenetics. 2009 Feb 16; 4(2): 98–99. Published online 2009 Feb 15. doi: 10.4161/epi.4.2.7858

PMCID:: PMC5842792

Abstract Article PDF–445K

Select item 56750027.

Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet

Naoki Tanaka, Shogo Takahashi, Xiao Hu, Lu Yu, Naoyuki Fujimori, Srujana Golla, Zhong-Ze Fang, Toshifumi Aoyama, Kristopher W. Krausz, Frank J. Gonzalez

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Biochim Biophys Acta. 2017 Dec; 1863(12): 3170–3182. Published online 2017 Aug 24. doi: 10.1016/j.bbadis.2017.08.017

PMCID:: PMC5675002

Abstract Article PDF–908K

Select item 50907078.

Gadd45a is a heterochromatin relaxer that enhances iPS cell generation

Keshi Chen, Qi Long, Tao Wang, Danyun Zhao, Yanshuang Zhou, Juntao Qi, Yi Wu, Shengbiao Li, Chunlan Chen, Xiaoming Zeng, Jianguo Yang, Zisong Zhou, Weiwen Qin, Xiyin Liu, Yuxing Li, Yingying Li, Xiaofen Huang, Dajiang Qin, Jiekai Chen, Guangjin Pan, Hans R Schöler, Guoliang Xu, Xingguo Liu, Duanqing Pei

EMBO Rep. 2016 Nov; 17(11): 1641–1656. Published online 2016 Oct 4. doi: 10.15252/embr.201642402

PMCID:: PMC5090707

Abstract Article PDF–2.3M

Select item 48322679.

DNA‐damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival

Susanne Wingert, Frederic B. Thalheimer, Nadine Haetscher, Maike Rehage, Timm Schroeder, Michael A. Rieger

Stem Cells. 2016 Mar; 34(3): 699–710. Published online 2016 Jan 26. doi: 10.1002/stem.2282

PMCID:: PMC4832267

Abstract Article PDF–818K

Select item 477800010.

New role and molecular mechanism of Gadd45a in hepatic ﬁbrosis

Liang Hong, Qing-Feng Sun, Ting-Yan Xu, Yang-He Wu, Hui Zhang, Rong-Quan Fu, Fu-Jing Cai, Qing-Qing Zhou, Ke Zhou, Qing-Wei Du, Dong Zhang, Shuang Xu, Ji-Guang Ding

World J Gastroenterol. 2016 Mar 7; 22(9): 2779–2788. Published online 2016 Mar 7. doi: 10.3748/wjg.v22.i9.2779

PMCID:: PMC4778000

Abstract Article PDF–1.6M

Select item 359429111.

GADD45α Induction by Nickel Negatively Regulates JNKs/p38 Activation via Promoting PP2Cα Expression

Yonghui Yu, Jingxia Li, Yu Wan, Jianyi Lu, Jimin Gao, Chuanshu Huang

PLoS One. 2013; 8(3): e57185. Published online 2013 Mar 11. doi: 10.1371/journal.pone.0057185

PMCID:: PMC3594291

Abstract Article PDF–1.7M

Select item 322051512.

GADD45A Protein Plays an Essential Role in Active DNA Demethylation during Terminal Osteogenic Differentiation of Adipose-derived Mesenchymal Stem Cells

Rui-peng Zhang, Jian-zhong Shao, Li-xin Xiang

J Biol Chem. 2011 Nov 25; 286(47): 41083–41094. Published online 2011 Sep 14. doi: 10.1074/jbc.M111.258715

PMCID:: PMC3220515

Abstract Article PDF–5.0M

Select item 319914213.

Gadd45a Functions as a Promoter or Suppressor of Breast Cancer Dependent on the Oncogenic Stress

Jennifer S. Tront, Yajue Haung, Albert A. Fornace, Jr., Barbara Hoffman, Dan A. Liebermann

Cancer Res. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: Cancer Res. 2010 Dec 1; 70(23): 9671–9681. Published online 2010 Nov 23. doi: 10.1158/0008-5472.CAN-10-2177

Correction in:: volume 71 on page 1506

PMCID:: PMC3199142

Abstract Article PDF–2.7M

Select item 35860314.

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

Q Zhan, K A Lord, I Alamo, Jr, M C Hollander, F Carrier, D Ron, K W Kohn, B Hoffman, D A Liebermann, A J Fornace, Jr

Mol Cell Biol. 1994 Apr; 14(4): 2361–2371. doi: 10.1128/mcb.14.4.2361

PMCID:: PMC358603

Summary Page Browse PDF–2.7M

Select item 1037908515.

GADD45A and GADD45B as Novel Biomarkers Associated with Chromatin Regulators in Renal Ischemia-Reperfusion Injury

Ming Xie, Ruiyan Xie, Pengcheng Huang, Desmond Y. H. Yap, Peng Wu

Int J Mol Sci. 2023 Jul; 24(14): 11304. Published online 2023 Jul 11. doi: 10.3390/ijms241411304

PMCID:: PMC10379085

Abstract Article PDF–11M

Select item 738515916.

GADD45α drives brown adipose tissue formation through upregulating PPARγ in mice

Wenjing You, Ziye Xu, Ye Sun, Teresa G. Valencak, Yizhen Wang, Tizhong Shan

Cell Death Dis. 2020 Jul; 11(7): 585. Published online 2020 Jul 27. doi: 10.1038/s41419-020-02802-5

PMCID:: PMC7385159

Abstract Article PDF–3.4M

Select item 660151117.

GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells

Katrin M. Schüle, Manuel Leichsenring, Tommaso Andreani, Viviana Vastolo, Medhavi Mallick, Michael U. Musheev, Emil Karaulanov, Christof Niehrs

Genes Dev. 2019 Jul 1; 33(13-14): 782–798. doi: 10.1101/gad.325696.119

PMCID:: PMC6601511

Abstract Article PDF–5.4M

Select item 617246118.

Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan

Daojun Diao, Hu Wang, Tangliang Li, Zhencan Shi, Xiaoqing Jin, Tobias Sperka, Xudong Zhu, Meimei Zhang, Fan Yang, Yusheng Cong, Li Shen, Qimin Zhan, Jing Yan, Zhangfa Song, Zhenyu Ju

EMBO Rep. 2018 Oct; 19(10): e45494. Published online 2018 Aug 20. doi: 10.15252/embr.201745494

PMCID:: PMC6172461

Abstract Article PDF–2.5M

Select item 608036519.

Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation

B Wang, Xing Fu, Mei-Jun Zhu, Min Du

J Mol Cell Biol. 2017 Aug; 9(4): 338–349. Published online 2017 Aug 5. doi: 10.1093/jmcb/mjx026

PMCID:: PMC6080365

Abstract Article PDF–1.6M

Select item 604951320.

Impaired DNA demethylation of C/EBP sites causes premature aging

Andrea Schäfer, Bernadette Mekker, Medhavi Mallick, Viviana Vastolo, Emil Karaulanov, Dominik Sebastian, Carina von der Lippen, Bernd Epe, Damien J. Downes, Carola Scholz, Christof Niehrs

Genes Dev. 2018 Jun 1; 32(11-12): 742–762. doi: 10.1101/gad.311969.118

PMCID:: PMC6049513

Abstract Article PDF–7.2M

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PMC Links for Gene (Select 13197) (78)
PMC
14631049[uid] (0)
Taxonomy
RE05089.5prime RE Drosophila melanogaster normalized Embryo pFlc-1 Drosophila me...
RE05089.5prime RE Drosophila melanogaster normalized Embryo pFlc-1 Drosophila melanogaster cDNA clone RE05089 5 similar to CG9028: FBan0009028 located on: 3L 70C8-70C9;: 04/11/2001, mRNA sequence
gi|14631049|gnl|dbEST|8940143|gb|BI 3.1|

Nucleotide
Homo sapiens neuroligin 4 X-linked (NLGN4X), transcript variant 1, mRNA
Homo sapiens neuroligin 4 X-linked (NLGN4X), transcript variant 1, mRNA
gi|1890327986|ref|NM_020742.4|

Nucleotide
14631049 (0)
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