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Select item 105145151.

The Cxcr2⁺ subset of the S100a8⁺ gastric granylocytic myeloid-derived suppressor cell population (G-MDSC) regulates gastric pathology

Krystal D. Kao, Helmut Grasberger, Mohamad El-Zaatari

Front Immunol. 2023; 14: 1147695. Published online 2023 Sep 8. doi: 10.3389/fimmu.2023.1147695

PMCID:: PMC10514515

Abstract Article PDF–15M

Select item 102391192.

CXCR2 expression during melanoma tumorigenesis controls transcriptional programs that facilitate tumor growth

J. Yang, K. Bergdorf, C. Yan, W. Luo, S. C. Chen, G.D. Ayers, Q. Liu, X. Liu, M. Boothby, V.L. Weiss, S. M. Groves, A. N. Oleskie, X. Zhang, D. Y. Maeda, J. A. Zebala, V. Quaranta, A. Richmond

Mol Cancer. 2023; 22: 92. Published online 2023 Jun 3. doi: 10.1186/s12943-023-01789-9

PMCID:: PMC10239119

Abstract Article PDF–2.2M

Select item 96066823.

CXCR2 intrinsically drives the maturation and function of neutrophils in mice

Pauline Delobel, Benjamin Ginter, Eliane Rubio, Karl Balabanian, Gwendal Lazennec

Front Immunol. 2022; 13: 1005551. Published online 2022 Oct 13. doi: 10.3389/fimmu.2022.1005551

PMCID:: PMC9606682

Abstract Article PDF–6.3M

Select item 84717054.

CXCR1/2 Inhibitor Ladarixin Ameliorates the Insulin Resistance of 3T3-L1 Adipocytes by Inhibiting Inflammation and Improving Insulin Signaling

Vanessa Castelli, Laura Brandolini, Michele d’Angelo, Cristina Giorgio, Margherita Alfonsetti, Pasquale Cocchiaro, Francesca Lombardi, Annamaria Cimini, Marcello Allegretti

Cells. 2021 Sep; 10(9): 2324. Published online 2021 Sep 6. doi: 10.3390/cells10092324

PMCID:: PMC8471705

Abstract Article PDF–5.3M

Select item 81001065.

Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms

Xiaojie Shi, Yue Wan, Nan Wang, Jiangchao Xiang, Tao Wang, Xiaofeng Yang, Ju Wang, Xuxue Dong, Liang Dong, Lei Yan, Yu Li, Lili Liu, Shinchen Hou, Zhenwei Zhong, Ian A. Wilson, Bei Yang, Guang Yang, Richard A. Lerner

Nat Commun. 2021; 12: 2547. Published online 2021 May 5. doi: 10.1038/s41467-021-22810-z

PMCID:: PMC8100106

Abstract Article PDF–3.1M

Select item 80279246.

Host Cxcr2-Dependent Regulation of Pancreatic Cancer Growth, Angiogenesis, and Metastasis

Abhilasha Purohit, Sugandha Saxena, Michelle Varney, Dipakkumar R. Prajapati, Jessica A. Kozel, Audrey Lazenby, Rakesh K. Singh

Am J Pathol. 2021 Apr; 191(4): 759–771. doi: 10.1016/j.ajpath.2021.01.002

PMCID:: PMC8027924

Abstract Article PDF–3.8M

Select item 79235937.

Astrocytes lure CXCR2-expressing CD4⁺ T cells to gray matter via TAK1-mediated chemokine production in a mouse model of multiple sclerosis

Yee Ming Khaw, Abbey Tierney, Claire Cunningham, Katiria Soto-Díaz, Eunjoo Kang, Andrew J. Steelman, Makoto Inoue

Proc Natl Acad Sci U S A. 2021 Feb 23; 118(8): e2017213118. Published online 2021 Feb 17. doi: 10.1073/pnas.2017213118

PMCID:: PMC7923593

Abstract Article PDF–1.9M

Select item 75012058.

CXCR2 signaling promotes secretory cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

Mohammad Awaji, Sugandha Saxena, Lingyun Wu, Dipakkumar R. Prajapati, Abhilasha Purohit, Michelle L. Varney, Sushil Kumar, Satyanarayana Rachagani, Quan P. Ly, Maneesh Jain, Surinder K. Batra, Rakesh K. Singh

FASEB J. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: FASEB J. 2020 Jul; 34(7): 9405–9418. Published online 2020 May 26. doi: 10.1096/fj.201902990R

PMCID:: PMC7501205

Abstract Article PDF–2.5M

Select item 70103169.

The health status alters the pituitary function and reproduction of mice in a Cxcr2-dependent manner

Colin Timaxian, Isabelle Raymond-Letron, Céline Bouclier, Linda Gulliver, Ludovic Le Corre, Karim Chébli, Anne Guillou, Patrice Mollard, Karl Balabanian, Gwendal Lazennec

Life Sci Alliance. 2020 Mar; 3(3): e201900599. Published online 2020 Feb 10. doi: 10.26508/lsa.201900599

PMCID:: PMC7010316

Abstract Article PDF–3.7M

Select item 700128410.

Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis

Yee Ming Khaw, Claire Cunningham, Abigail Tierney, Mayandi Sivaguru, Makoto Inoue

J Neuroinflammation. 2020; 17: 49. Published online 2020 Feb 4. doi: 10.1186/s12974-020-1730-y

PMCID:: PMC7001284

Abstract Article PDF–2.1M

Select item 661503511.

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition

Vanessa Nomellini, Douglas E. Faunce, Christian R. Gomez, Elizabeth J. Kovacs

J Leukoc Biol. Author manuscript; available in PMC 2019 Jul 9.

Published in final edited form as: J Leukoc Biol. 2008 Jun; 83(6): 1493–1501. Published online 2008 Mar 13. doi: 10.1189/jlb.1007672

PMCID:: PMC6615035

Abstract Article PDF–1.4M

Select item 658865412.

Mutations in foregut SOX2⁺ cells induce efficient proliferation via CXCR2 pathway

Tomoaki Hishida, Eric Vazquez-Ferrer, Yuriko Hishida-Nozaki, Ignacio Sancho-Martinez, Yuta Takahashi, Fumiyuki Hatanaka, Jun Wu, Alejandro Ocampo, Pradeep Reddy, Min-Zu Wu, Laurie Gerken, Reuben J. Shaw, Concepcion Rodriguez Esteban, Christopher Benner, Hiroshi Nakagawa, Pedro Guillen Garcia, Estrella Nuñez Delicado, Antoni Castells, Josep M. Campistol, Guang-Hui Liu, Juan Carlos Izpisua Belmonte

Protein Cell. 2019 Jul; 10(7): 485–495. Published online 2019 Apr 30. doi: 10.1007/s13238-019-0630-3

PMCID:: PMC6588654

Abstract Article PDF–1.6M

Select item 639211413.

The chemokine receptor CXCR2 contributes to murine adipocyte development

Douglas P. Dyer, Joan Boix Nebot, Christopher J. Kelly, Laura Medina‐Ruiz, Fabian Schuette, Gerard J Graham

J Leukoc Biol. 2019 Mar; 105(3): 497–506. Published online 2018 Dec 5. doi: 10.1002/JLB.1A0618-216RR

PMCID:: PMC6392114

Abstract Article PDF–2.5M

Select item 625197514.

Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

Teresa Arnandis, Pedro Monteiro, Sophie D. Adams, Victoria Louise Bridgeman, Vinothini Rajeeve, Emanuela Gadaleta, Jacek Marzec, Claude Chelala, Ilaria Malanchi, Pedro R. Cutillas, Susana A. Godinho

Dev Cell. 2018 Nov 19; 47(4): 409–424.e9. doi: 10.1016/j.devcel.2018.10.026

PMCID:: PMC6251975

Abstract Article

Select item 587711815.

Tumor conditions induce bone marrow expansion of granulocytic, but not monocytic, immunosuppressive leukocytes with increased CXCR2 expression in mice

Zhen Bian, Lei Shi, Mahathi Venkataramani, Ahmed Mansour Abdelaal, Courtney Culpepper, Koby Kidder, Hongwei Liang, Ke Zen, Yuan Liu

Eur J Immunol. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Eur J Immunol. 2018 Mar; 48(3): 532–542. Published online 2017 Dec 8. doi: 10.1002/eji.201746976

PMCID:: PMC5877118

Abstract Article PDF–1.2M

Select item 583370516.

Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis

Zongshan Shen, Jiancheng Wang, Qiting Huang, Yue Shi, Zhewei Wei, Xiaoran Zhang, Yuan Qiu, Min Zhang, Yi Wang, Wei Qin, Shuheng Huang, Yinong Huang, Xin Liu, Kai Xia, Xinchun Zhang, Zhengmei Lin

Cell Death Dis. 2018 Feb; 9(2): 229. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0310-x

PMCID:: PMC5833705

Abstract Article PDF–5.8M

Select item 553867717.

Cxcr2 signaling and the microbiome suppress inflammation, bile duct injury, and the phenotype of experimental biliary atresia

Junbae Jee, Reena Mourya, Pranavkumar Shivakumar, Lin Fei, Michael Wagner, Jorge A. Bezerra

PLoS One. 2017; 12(8): e0182089. Published online 2017 Aug 1. doi: 10.1371/journal.pone.0182089

PMCID:: PMC5538677

Abstract Article PDF–11M

Select item 529004018.

TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2⁺ neutrophils

P F Yu, Y Huang, Y Y Han, L Y Lin, W H Sun, A B Rabson, Y Wang, Y F Shi

Oncogene. 2017 Jan 26; 36(4): 482–490. Published online 2016 Jul 4. doi: 10.1038/onc.2016.217

PMCID:: PMC5290040

Abstract Article PDF–2.3M

Select item 483317819.

CXCR2 inhibition suppresses acute and chronic pancreatic inflammation

Colin W Steele, Saadia A Karim, Mona Foth, Loveena Rishi, Joshua DG Leach, Ross J Porter, Colin Nixon, TR Jeffry Evans, C Ross Carter, Robert JB Nibbs, Owen J Sansom, Jennifer P Morton

J Pathol. 2015 Sep; 237(1): 85–97. Published online 2015 Jun 4. doi: 10.1002/path.4555

PMCID:: PMC4833178

Abstract Article PDF–5.7M

Select item 482154620.

Induction of CXCR2 ligands, stem cell-like phenotype, and metastasis in chemotherapy-resistant breast cancer cells

Bhawna Sharma, Michelle L Varney, Sugandha Saxena, Lingyun Wu, Rakesh K Singh

Cancer Lett. Author manuscript; available in PMC 2017 Mar 28.

Published in final edited form as: Cancer Lett. 2016 Mar 28; 372(2): 192–200. Published online 2016 Jan 12. doi: 10.1016/j.canlet.2015.12.011

PMCID:: PMC4821546

Abstract Article PDF–1005K

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