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Select item 89737011.

Angiotensin-(1-7) ameliorates high glucose-induced vascular endothelial injury through suppressing chloride channel 3

Fei Cheng, Jing Liu, Zhuolin Guo, Shicheng Li, Jingfu Chen, Chang Tu, Fengzhou Fu, Bai Shen, Xiaojie Zhang, Guohua Lai, Jun Lan

Bioengineered. 2022; 13(2): 4100–4111. Published online 2022 Feb 15. doi: 10.1080/21655979.2021.1997695

PMCID:: PMC8973701

Abstract Article PDF–2.9M

Select item 83653732.

The role of voltage-gated chloride channels in the epileptogenesis of temporal lobe epilepsy

Kai-Feng Shen, Xiao-Lin Yang, Guo-Long Liu, Gang Zhu, Zhong-Ke Wang, Xian-Jun Shi, Ting-Ting Wang, Zhi-Feng Wu, Sheng-Qing Lv, Shi-Yong Liu, Hui Yang, Chun-Qing Zhang

EBioMedicine. 2021 Aug; 70: 103537. Published online 2021 Aug 11. doi: 10.1016/j.ebiom.2021.103537

PMCID:: PMC8365373

Abstract Article PDF–4.1M

Select item 61254333.

Transcriptional repression of human epidermal growth factor receptor 2 by ClC‐3 Cl⁻/H⁺ transporter inhibition in human breast cancer cells

Mayu Fujimoto, Hiroaki Kito, Junko Kajikuri, Susumu Ohya

Cancer Sci. 2018 Sep; 109(9): 2781–2791. Published online 2018 Jul 28. doi: 10.1111/cas.13715

PMCID:: PMC6125433

Abstract Article PDF–1.3M

Select item 47463544.

ClC-3 Expression and Its Association with Hyperglycemia Induced HT22 Hippocampal Neuronal Cell Apoptosis

Feiyan Fan, Tao Liu, Xin Wang, Dongni Ren, Hui Liu, Pengxing Zhang, Zhen Wang, Nan Liu, Qian Li, Yanyang Tu, Jianfang Fu

J Diabetes Res. 2016; 2016: 2984380. Published online 2016 Jan 26. doi: 10.1155/2016/2984380

PMCID:: PMC4746354

Abstract Article PDF–2.3M

Select item 47284225.

Threonine532 phosphorylation in ClC‐3 channels is required for angiotensin II‐induced Cl⁻ current and migration in cultured vascular smooth muscle cells

Ming‐Ming Ma, Cai‐Xia Lin, Can‐Zhao Liu, Min Gao, Lu Sun, Yong‐Bo Tang, Jia‐Guo Zhou, Guan‐Lei Wang, Yong‐Yuan Guan

Br J Pharmacol. 2016 Feb; 173(3): 529–544. Published online 2016 Jan 15. doi: 10.1111/bph.13385

PMCID:: PMC4728422

Abstract Article PDF–2.2M

Select item 46462426.

Neuronal ClC-3 Splice Variants Differ in Subcellular Localizations, but Mediate Identical Transport Functions

Raul E. Guzman, Erick Miranda-Laferte, Arne Franzen, Christoph Fahlke

J Biol Chem. 2015 Oct 23; 290(43): 25851–25862. Published online 2015 Sep 4. doi: 10.1074/jbc.M115.668186

PMCID:: PMC4646242

Abstract Article PDF–4.9M

Select item 40443147.

Increase in Hypotonic Stress-Induced Endocytic Activity in Macrophages via ClC-3

Yutao Yan, Yu Ding, Bingxia Ming, Wenjiao Du, Xiaoling Kong, Li Tian, Fang Zheng, Min Fang, Zheng Tan, Feili Gong

Mol Cells. 2014 May; 37(5): 418–425. Published online 2014 May 16. doi: 10.14348/molcells.2014.0031

PMCID:: PMC4044314

Abstract Article PDF–563K

Select item 37091868.

Activation of Volume Regulated Chloride Channels Protects Myocardium from Ischemia/reperfusion Damage in Second-window Ischemic Preconditioning

Nathan D. Bozeat, Sunny Yang Xiang, Linda L. Ye, Tammy Y. Yao, Marie L. Duan, Dean J. Burkin, Fred S. Lamb, Dayue Darrel Duan

Cell Physiol Biochem. 2011 Dec; 28(6): 1265–1278. doi: 10.1159/000335858

PMCID:: PMC3709186

Abstract Article PDF–1.5M

Select item 35917119.

CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral–CA1 synapses

Laurel M Farmer, Brandy N Le, Deborah J Nelson

J Physiol. 2013 Feb 15; 591(Pt 4): 1001–1015. Published online 2012 Nov 19. doi: 10.1113/jphysiol.2012.243485

PMCID:: PMC3591711

Abstract Article PDF–1.9M

Select item 287914610.

Cardiac Specific, Inducible ClC-3 Gene Deletion Eliminates Native Volume-Sensitive Chloride Channels and Produces Myocardial Hypertrophy in Adult Mice

Dazhi Xiong, Nathanael S. Heyman, Judith Airey, Mi Zhang, Cherie A. Singer, Shanti Rawat, Linda Ye, Rebecca Evans, Dean J. Burkin, Honglin Tian, Diana T McCloskey, Maria Valencik, Fiona C. Britton, Dayue Duan, Joseph R. Hume

J Mol Cell Cardiol. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2010 Jan; 48(1): 211–219. Published online 2009 Jul 15. doi: 10.1016/j.yjmcc.2009.07.003

PMCID:: PMC2879146

Abstract Article PDF–1.2M

Select item 280731411.

The ClC-3 Cl⁻/H⁺ Antiporter Becomes Uncoupled at Low Extracellular pH

James J. Matsuda, Mohammed S. Filali, Malia M. Collins, Kenneth A. Volk, Fred S. Lamb

J Biol Chem. 2010 Jan 22; 285(4): 2569–2579. Published online 2009 Nov 19. doi: 10.1074/jbc.M109.018002

PMCID:: PMC2807314

Abstract Article PDF–2.6M

Select item 277819312.

The Granular Chloride Channel ClC-3 Is Permissive For Insulin Secretion

Ludmila V. Deriy, Erwin A. Gomez, David A. Jacobson, XueQing Wang, Jessika A. Hopson, Xiang Y. Liu, Guangping Zhang, Vytautas P. Bindokas, Louis H. Philipson, Deborah J. Nelson

Cell Metab. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Cell Metab. 2009 Oct; 10(4): 316–323. doi: 10.1016/j.cmet.2009.08.012

PMCID:: PMC2778193

Abstract Article PDF–3.3M

Select item 259070513.

ClC-3 and IClswell are Required for Normal Neutrophil Chemotaxis and Shape Change

A. Paige Davis Volk, Christine K. Heise, Jami L. Hougen, Christopher M. Artman, Kenneth A. Volk, Deborah Wessels, David R. Soll, William M. Nauseef, Fred S. Lamb, Jessica G. Moreland

J Biol Chem. 2008 Dec 5; 283(49): 34315–34326. doi: 10.1074/jbc.M803141200

PMCID:: PMC2590705

Abstract Article PDF–991K

Select item 229064314.

Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl⁻ channel gene

Jorge Arreola, Ted Begenisich, Keith Nehrke, Ha-Van Nguyen, Keerang Park, Linda Richardson, Baoli Yang, Brian C Schutte, Fred S Lamb, James E Melvin

J Physiol. 2002 Nov 15; 545(Pt 1): 207–216. Published online 2002 Sep 27. doi: 10.1113/jphysiol.2002.021980

PMCID:: PMC2290643

Abstract Article PDF–592K

Select item 166493415.

Identification of an N-terminal amino acid of the CLC-3 chloride channel critical in phosphorylation-dependent activation of a CaMKII-activated chloride current

N C Robinson, P Huang, M A Kaetzel, Fred S Lamb, D J Nelson

J Physiol. 2004 Apr 15; 556(Pt 2): 353–368. Published online 2004 Jan 30. doi: 10.1113/jphysiol.2003.058032

PMCID:: PMC1664934

Abstract Article PDF–692K

Select item 1104385016.

Chloride/proton antiporters ClC3 and ClC5 support bone formation in mice

Irina L. Tourkova, Quitterie C. Larrouture, Silvia Liu, Jianhua Luo, Katherine E. Shipman, Kelechi M. Onwuka, Ora A. Weisz, Vladimir Riazanski, Deborah J. Nelson, Matthew L. MacDonald, Paul H. Schlesinger, Harry C. Blair

Bone Rep. 2024 Jun; 21: 101763. Published online 2024 Apr 16. doi: 10.1016/j.bonr.2024.101763

PMCID:: PMC11043850

Abstract Article PDF–14M

Select item 838728417.

Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders

Anna R. Duncan, Maya M. Polovitskaya, Héctor Gaitán-Peñas, Sara Bertelli, Grace E. VanNoy, Patricia E. Grant, Anne O’Donnell-Luria, Zaheer Valivullah, Alysia Kern Lovgren, Elaina M. England, Emanuele Agolini, Jill A. Madden, Klaus Schmitz-Abe, Amy Kritzer, Pamela Hawley, Antonio Novelli, Paolo Alfieri, Giovanna Stefania Colafati, Dagmar Wieczorek, Konrad Platzer, Johannes Luppe, Margarete Koch-Hogrebe, Rami Abou Jamra, Juanita Neira-Fresneda, Anna Lehman, Cornelius F. Boerkoel, Kimberly Seath, Lorne Clarke, CAUSES Study, Yvette van Ierland, Emanuela Argilli, Elliott H. Sherr, Andrea Maiorana, Thilo Diel, Maja Hempel, Tatjana Bierhals, Raúl Estévez, Thomas J. Jentsch, Michael Pusch, Pankaj B. Agrawal

Am J Hum Genet. 2021 Aug 5; 108(8): 1450–1465. Published online 2021 Jun 28. doi: 10.1016/j.ajhg.2021.06.003

PMCID:: PMC8387284

Abstract Article PDF–3.1M

Select item 719691818.

Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration

Stefanie Weinert, Niclas Gimber, Dorothea Deuschel, Till Stuhlmann, Dmytro Puchkov, Zohreh Farsi, Carmen F Ludwig, Gaia Novarino, Karen I López‐Cayuqueo, Rosa Planells‐Cases, Thomas J Jentsch

EMBO J. 2020 May 4; 39(9): e103358. Published online 2020 Mar 2. doi: 10.15252/embj.2019103358

PMCID:: PMC7196918

Abstract Article PDF–4.9M

Select item 667134219.

Role of the Vesicular Chloride Transporter ClC-3 in Neuroendocrine Tissue

Tanja Maritzen, Damien J. Keating, Ioana Neagoe, Anselm A. Zdebik, Thomas J. Jentsch

J Neurosci. 2008 Oct 15; 28(42): 10587–10598. doi: 10.1523/JNEUROSCI.3750-08.2008

PMCID:: PMC6671342

Abstract Article PDF–665K

Select item 381725220.

Regulation of cell proliferation by intermediate-conductance Ca²⁺-activated potassium and volume-sensitive chloride channels in mouse mesenchymal stem cells

Rong Tao, Chu-Pak Lau, Hung-Fat Tse, Gui-Rong Li

Am J Physiol Cell Physiol. 2008 Nov; 295(5): C1409–C1416. doi: 10.1152/ajpcell.00268.2008

PMCID:: PMC3817252

Abstract Article

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PMC Links for Gene (Select 12725) (43)
PMC
PREDICTED: Mus musculus RIKEN cDNA 2600009E05 gene, transcript variant 4 (260000...
PREDICTED: Mus musculus RIKEN cDNA 2600009E05 gene, transcript variant 4 (2600009E05Rik), mRNA
gi|94367232|ref|XM_901934.2|

Nucleotide
Homo sapiens cDNA FLJ41423 fis, clone BRHIP2003242
Homo sapiens cDNA FLJ41423 fis, clone BRHIP2003242
gi|34528959|dbj|AK123417.1|

Nucleotide
PREDICTED: Globicephala melas hexosaminidase subunit beta (HEXB), transcript var...
PREDICTED: Globicephala melas hexosaminidase subunit beta (HEXB), transcript variant X6, mRNA
gi|2597740279|ref|XM_060295895.1|

Nucleotide
E3 ubiquitin-protein ligase rififylin isoform X4 [Pan troglodytes]
E3 ubiquitin-protein ligase rififylin isoform X4 [Pan troglodytes]
gi|1034121338|ref|XP_016787492.1|

Protein

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