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Select item 58274031.

Host Tumor Suppressor p18^INK4c Functions as a Potent Cell-Intrinsic Inhibitor of Murine Gammaherpesvirus 68 Reactivation and Pathogenesis

Brian F. Niemeyer, Lauren M. Oko, Eva M. Medina, Darby G. Oldenburg, Douglas W. White, Carlyne D. Cool, Eric T. Clambey, Linda F. van Dyk

J Virol. 2018 Mar 15; 92(6): e01604-17. Prepublished online 2018 Jan 3. Published online 2018 Feb 26. doi: 10.1128/JVI.01604-17

PMCID:: PMC5827403

Abstract Article PDF–2.4M

Select item 43946092.

Identification of p18^INK4c as a Tumor Suppressor Gene in Glioblastoma Multiforme

David A. Solomon, Jung-Sik Kim, Sultan Jenkins, Habtom Ressom, Michael Huang, Nicholas Coppa, Lauren Mabanta, Darell Bigner, Hai Yan, Walter Jean, Todd Waldman

Cancer Res. Author manuscript; available in PMC 2015 Apr 13.

Published in final edited form as: Cancer Res. 2008 Apr 15; 68(8): 2564–2569. Published online 2008 Apr 1. doi: 10.1158/0008-5472.CAN-07-6388

PMCID:: PMC4394609

Abstract Article PDF–776K

Select item 39488963.

Regulation of T Cell Differentiation and Alloimmunity by the Cyclin-Dependent Kinase Inhibitor p18ink4c

Emily A. Rowell, Liqing Wang, Neelanjana Chunder, Wayne W. Hancock, Andrew D. Wells

PLoS One. 2014; 9(3): e91587. Published online 2014 Mar 10. doi: 10.1371/journal.pone.0091587

PMCID:: PMC3948896

Abstract Article PDF–931K

Select item 37748324.

Cyclin-dependent kinase inhibitor Cdkn2c regulates B cell homeostasis and function in the NZM2410-derived murine lupus susceptibility locus Sle2c1

Zhiwei Xu, Hari-Hara SK Potula, Anusha Vallurupalli, Daniel Perry, Henry Baker, Byron P. Croker, Igor Dozmorov, Laurence Morel

J Immunol. Author manuscript; available in PMC 2013 Sep 16.

Published in final edited form as: J Immunol. 2011 Jun 15; 186(12): 6673–6682. Published online 2011 May 4. doi: 10.4049/jimmunol.1002544

PMCID:: PMC3774832

Abstract Article PDF–1.8M

Select item 33764685.

Cyclin Dependent Kinase Inhibitors Differentially Modulate Synergistic Cytokine Responsiveness of Hematopoietic Progenitor Cells

Hal E. Broxmeyer, David S. Franklin, Scott Cooper, Giao Hangoc, Charlie Mantel

Stem Cells Dev. 2012 Jul 1; 21(10): 1597–1603. Published online 2011 Sep 21. doi: 10.1089/scd.2011.0476

PMCID:: PMC3376468

Abstract Article PDF–435K

Select item 1411536.

Haploinsufficiency of p18^INK4c Sensitizes Mice to Carcinogen-Induced Tumorigenesis

Feng Bai, Xin-Hai Pei, Virginia L. Godfrey, Yue Xiong

Mol Cell Biol. 2003 Feb; 23(4): 1269–1277. doi: 10.1128/MCB.23.4.1269-1277.2003

PMCID:: PMC141153

Abstract Article PDF–861K

Select item 1214877.

Coupled Transcriptional and Translational Control of Cyclin-Dependent Kinase Inhibitor p18^INK4c Expression during Myogenesis

Dawn E. Phelps, Kuang-Ming Hsiao, Yan Li, Nanpin Hu, David S. Franklin, Eva Westphal, Eva Y.-H. P. Lee, Yue Xiong

Mol Cell Biol. 1998 Apr; 18(4): 2334–2343. doi: 10.1128/mcb.18.4.2334

PMCID:: PMC121487

Abstract Article PDF–1016K

Select item 86929048.

Loss of function of GATA3 induces basal-like mammary tumors

Feng Bai, Chenglong Zheng, Xiong Liu, Ho Lam Chan, Shiqin Liu, Jinshan Ma, Sijia Ren, Wei-Guo Zhu, Xin-Hai Pei

Theranostics. 2022; 12(2): 720–733. Published online 2022 Jan 1. doi: 10.7150/thno.65796

PMCID:: PMC8692904

Abstract Article PDF–2.7M

Select item 53254219.

Gata3 restrains B cell proliferation and cooperates with p18^INK4c to repress B cell lymphomagenesis

Shiqin Liu, Ho Lam Chan, Feng Bai, Jinshan Ma, Alexandria Scott, David J. Robbins, Anthony J. Capobianco, Ping Zhu, Xin-Hai Pei

Oncotarget. 2016 Sep 27; 7(39): 64007–64020. Published online 2016 Aug 31. doi: 10.18632/oncotarget.11746

PMCID:: PMC5325421

Abstract Article PDF–4.3M

Select item 462110010.

A Conserved Gammaherpesvirus Cyclin Specifically Bypasses Host p18^INK4c To Promote Reactivation from Latency

Lisa M. Williams, Brian F. Niemeyer, David S. Franklin, Eric T. Clambey, Linda F. van Dyk

J Virol. 2015 Nov 1; 89(21): 10821–10831. Published online 2015 Aug 19. doi: 10.1128/JVI.00891-15

PMCID:: PMC4621100

Abstract Article PDF–1.7M

Select item 450812511.

Small-molecule inhibitors targeting INK4 protein p18^INK4C enhance ex vivo expansion of haematopoietic stem cells

Yingdai Gao, Peng Yang, Hongmei Shen, Hui Yu, Xianmin Song, Liyan Zhang, Peng Zhang, Haizi Cheng, Zhaojun Xie, Sha Hao, Fang Dong, Shihui Ma, Qing Ji, Patrick Bartlow, Yahui Ding, Lirong Wang, Haibin Liu, Yanxin Li, Hui Cheng, Weimin Miao, Weiping Yuan, Youzhong Yuan, Tao Cheng, Xiang-Qun Xie

Nat Commun. Author manuscript; available in PMC 2015 Jul 20.

Published in final edited form as: Nat Commun. 2015; 6: 6328. Published online 2015 Feb 18. doi: 10.1038/ncomms7328

PMCID:: PMC4508125

Abstract Article PDF–1.7M

Select item 443594812.

An Important Role of CDK Inhibitor p18^INK4c in Modulating Antigen Receptor-Mediated T Cell Proliferation

Grigoriy I. Kovalev, David S. Franklin, V. McNeil Coffield, Yue Xiong, Lishan Su

J Immunol. Author manuscript; available in PMC 2015 May 18.

Published in final edited form as: J Immunol. 2001 Sep 15; 167(6): 3285–3292. doi: 10.4049/jimmunol.167.6.3285

PMCID:: PMC4435948

Abstract Article PDF–1.0M

Select item 306232713.

Noxa mediates p18^INK4c cell-cycle control of homeostasis in B cells and plasma cell precursors

Jamieson Bretz, Josefina Garcia, Xiangao Huang, Lin Kang, Yang Zhang, Kai-Michael Toellner, Selina Chen-Kiang

Blood. 2011 Feb 17; 117(7): 2179–2188. Prepublished online 2010 Dec 16. doi: 10.1182/blood-2010-06-288027

PMCID:: PMC3062327

Abstract Article

Select item 289643814.

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

Olivier Ayrault, Haotian Zhao, Frederique Zindy, Chunxu Qu, Charles J. Sherr, Martine F. Roussel

Cancer Res. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Cancer Res. 2010 Jul 1; 70(13): 5618–5627. Published online 2010 Jun 1. doi: 10.1158/0008-5472.CAN-09-3740

PMCID:: PMC2896438

Abstract Article PDF–3.2M

Select item 262940815.

p18^Ink4cand p53 act as tumor suppressors in Cyclin D1-driven primitive neuroectodermal tumor

Raya Saab, Carlos Rodriguez-Galindo, Kelly Matmati, Jerold E. Rehg, Shannon H. Baumer, Joseph D. Khoury, Catherine Billups, Geoffrey Neale, Kathleen J. Helton, Stephen X. Skapek

Cancer Res. Author manuscript; available in PMC 2010 Jan 15.

Published in final edited form as: Cancer Res. 2009 Jan 15; 69(2): 440–448. doi: 10.1158/0008-5472.CAN-08-1892

PMCID:: PMC2629408

Abstract Article PDF–2.8M

Select item 262844416.

Differential post-transcriptional regulation of two Ink4 proteins, p18^Ink4c and p19^Ink4d

Antoine Forget, Olivier Ayrault, Willem den Besten, Mei-Ling Kuo, Charles J. Sherr, Martine F. Roussel

Cell Cycle. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Cell Cycle. 2008 Dec; 7(23): 3737–3746. Published online 2008 Dec 13. doi: 10.4161/cc.7.23.7187

PMCID:: PMC2628444

Abstract Article PDF–1.1M

Select item 189591317.

Hematopoietic stem cell exhaustion impacted by p18^INK4C and p21^Cip1/Waf1 in opposite manners

Hui Yu, Youzhong Yuan, Hongmei Shen, Tao Cheng

Blood. 2006 Feb 1; 107(3): 1200–1206. Prepublished online 2005 Oct 18. doi: 10.1182/blood-2005-02-0685

PMCID:: PMC1895913

Abstract Article

Select item 44485118.

Genetic Evidence for Functional Dependency of p18^Ink4c on Cdk4

Xin-Hai Pei, Feng Bai, Tateki Tsutsui, Hiroaki Kiyokawa, Yue Xiong

Mol Cell Biol. 2004 Aug; 24(15): 6653–6664. doi: 10.1128/MCB.24.15.6653-6664.2004

PMCID:: PMC444851

Abstract Article PDF–1.3M

Select item 31717319.

CDK inhibitors p18^INK4c and p27^Kip1 mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

David S. Franklin, Virginia L. Godfrey, Hayyoung Lee, Grigoriy I. Kovalev, Robert Schoonhoven, Selina Chen-Kiang, Lishan Su, Yue Xiong

Genes Dev. 1998 Sep 15; 12(18): 2899–2911. doi: 10.1101/gad.12.18.2899

PMCID:: PMC317173

Abstract Article PDF–557K

Select item 31393820.

Limited overlapping roles of P15^INK4b and P18^INK4c cell cycle inhibitors in proliferation and tumorigenesis

Esther Latres, Marcos Malumbres, Rocío Sotillo, Javier Martín, Sagrario Ortega, Juan Martín-Caballero, Juana María Flores, Carlos Cordón-Cardo, Mariano Barbacid

EMBO J. 2000 Jul 3; 19(13): 3496–3506. doi: 10.1093/emboj/19.13.3496

PMCID:: PMC313938

Abstract Article PDF–964K

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