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Select item 111033901.

Combination of androgen and estrogen improves asthma by mediating Runx3 expression

Yi He, Binaya Wasti, Yu Yuan, Zhifeng Chen, Wentao Duan, Jingsi Jia, Bing Xiao, Xiufeng Zhang, Jianmin Li, Qingping Zeng, Libing Ma, Shaokun Liu, Xudong Xiang

Int J Med Sci. 2024; 21(6): 1003–1015. Published online 2024 Apr 8. doi: 10.7150/ijms.91253

PMCID:: PMC11103390

Abstract Article PDF–5.4M

Select item 106057642.

Runx3 Restoration Regresses K-Ras-Activated Mouse Lung Cancers and Inhibits Recurrence

Ja-Yeol Lee, Jung-Won Lee, Tae-Geun Park, Sang-Hyun Han, Seo-Yeong Yoo, Kyoung-Mi Jung, Da-Mi Kim, Ok-Jun Lee, Dohun Kim, Xin-Zi Chi, Eung-Gook Kim, You-Soub Lee, Suk-Chul Bae

Cells. 2023 Oct; 12(20): 2438. Published online 2023 Oct 11. doi: 10.3390/cells12202438

PMCID:: PMC10605764

Abstract Article PDF–2.4M

Select item 103179903.

RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade

Vincent Oei, Linda Shyue Huey Chuang, Junichi Matsuo, Supriya Srivastava, Ming Teh, Yoshiaki Ito

Commun Biol. 2023; 6: 689. Published online 2023 Jul 3. doi: 10.1038/s42003-023-05037-0

PMCID:: PMC10317990

Abstract Article PDF–7.1M

Select item 100143504.

Enforced expression of Runx3 improved CAR-T cell potency in solid tumor via enhancing resistance to activation-induced cell death

Yi Wang, Honghong Zhang, Guoxiu Du, Hong Luo, Jingwen Su, Yansha Sun, Min Zhou, Bizhi Shi, Henry Q.X. Li, Hua Jiang, Zonghai Li

Mol Ther. 2023 Mar 1; 31(3): 701–714. Published online 2022 Dec 15. doi: 10.1016/j.ymthe.2022.12.009

PMCID:: PMC10014350

Abstract Article PDF–3.8M

Select item 92893705.

Transcription Factor RUNX3 Mediates Plasticity of ThGM Cells Toward Th1 Phenotype

Javad Rasouli, Giacomo Casella, Weifeng Zhang, Dan Xiao, Gaurav Kumar, Paolo Fortina, Guang-Xian Zhang, Bogoljub Ciric, Abdolmohamad Rostami

Front Immunol. 2022; 13: 912583. Published online 2022 Jul 4. doi: 10.3389/fimmu.2022.912583

PMCID:: PMC9289370

Abstract Article PDF–8.9M

Select item 89338476.

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach

Daisuke Douchi, Akihiro Yamamura, Junichi Matsuo, Jung-Won Lee, Napat Nuttonmanit, Yi Hui Melissa Lim, Kazuto Suda, Mitsuhiro Shimura, Sabirah Chen, ShuChin Pang, Kazuyoshi Kohu, Mari Kaneko, Hiroshi Kiyonari, Atsushi Kaneda, Hideyuki Yoshida, Ichiro Taniuchi, Motomi Osato, Henry Yang, Michiaki Unno, Jimmy Bok-Yan So, Khay Guan Yeoh, Linda Shyue Huey Chuang, Suk-Chul Bae, Yoshiaki Ito

Cell Mol Gastroenterol Hepatol. 2022; 13(5): 1317–1345. Published online 2022 Jan 21. doi: 10.1016/j.jcmgh.2022.01.010

PMCID:: PMC8933847

Abstract Article PDF–24M

Select item 73813837.

Peripherally induced brain tissue-resident memory CD8⁺ T cells mediate protection against CNS infection

Stina L. Urban, Isaac J. Jensen, Qiang Shan, Lecia L. Pewe, Hai-Hui Xue, Vladimir P. Badovinac, John T. Harty

Nat Immunol. Author manuscript; available in PMC 2020 Dec 22.

Published in final edited form as: Nat Immunol. 2020 Aug; 21(8): 938–949. Published online 2020 Jun 22. doi: 10.1038/s41590-020-0711-8

PMCID:: PMC7381383

Abstract Article PDF–3.5M

Select item 66917228.

Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors

Motoko Y Kimura, Julien Thomas, Xuguang Tai, Terry I Guinter, Miho Shinzawa, Ruth Etzensperger, Zhenhu Li, Paul Love, Toshinori Nakayama, Alfred Singer

Nat Immunol. Author manuscript; available in PMC 2019 Aug 13.

Published in final edited form as: Nat Immunol. 2016 Dec; 17(12): 1415–1423. Published online 2016 Sep 26. doi: 10.1038/ni.3560

PMCID:: PMC6691722

Abstract Article PDF–1.7M

Select item 57479649.

Runx3 programs CD8⁺ T cell residency in non-lymphoid tissues and tumors

J. Justin Milner, Clara Toma, Bingfei Yu, Kai Zhang, Kyla Omilusik, Anthony T. Phan, Dapeng Wang, Adam J. Getzler, Toan Nguyen, Shane Crotty, Wei Wang, Matthew E. Pipkin, Ananda W. Goldrath

Nature. Author manuscript; available in PMC 2018 Jun 6.

Published in final edited form as: Nature. 2017 Dec 14; 552(7684): 253–257. Published online 2017 Dec 6. doi: 10.1038/nature24993

PMCID:: PMC5747964

Article PDF–1.1M

Select item 508173510.

Runx3 transcription factor regulates ovarian functions and ovulation in female mice

Fumiya OJIMA, Yuka SAITO, Yukiko TSUCHIYA, Daichi KAYO, Syusuke TANIUCHI, Maho OGOSHI, Hiroshi FUKAMACHI, Sakae TAKEUCHI, Sumio TAKAHASHI

J Reprod Dev. 2016 Oct; 62(5): 479–486. Published online 2016 Jun 13. doi: 10.1262/jrd.2016-005

PMCID:: PMC5081735

Abstract Article PDF–2.5M

Select item 453007411.

Restriction of non-permissive RUNX3 protein expression in T lymphocytes by the Kozak sequence

Byungil Kim, Yo Sasaki, Takeshi Egawa

J Immunol. Author manuscript; available in PMC 2016 Aug 15.

Published in final edited form as: J Immunol. 2015 Aug 15; 195(4): 1517–1523. Published online 2015 Jul 13. doi: 10.4049/jimmunol.1501039

PMCID:: PMC4530074

Abstract Article PDF–2.4M

Select item 382742012.

Runx3-mediated Transcriptional Program in Cytotoxic Lymphocytes

Joseph Lotem, Ditsa Levanon, Varda Negreanu, Dena Leshkowitz, Gilgi Friedlander, Yoram Groner

PLoS One. 2013; 8(11): e80467. Published online 2013 Nov 13. doi: 10.1371/journal.pone.0080467

PMCID:: PMC3827420

Abstract Article PDF–2.3M

Select item 146434913.

Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3

Merav Yarmus, Eilon Woolf, Yael Bernstein, Ofer Fainaru, Varda Negreanu, Ditsa Levanon, Yoram Groner

Proc Natl Acad Sci U S A. 2006 May 9; 103(19): 7384–7389. Published online 2006 May 1. doi: 10.1073/pnas.0602470103

PMCID:: PMC1464349

Abstract Article PDF–1.1M

Select item 1116000514.

In vitro differentiation of Runx3^−/–p53^−/– gastric epithelial cells into intestinal type cells

Hiroshi Fukamachi, Ayako Mimata, Issei Tanaka, Kosei Ito, Yoshiaki Ito, Yasuhito Yuasa

Cancer Sci. 2008 Apr; 99(4): 671–676. Published online 2008 Mar 3. doi: 10.1111/j.1349-7006.2008.00732.x

PMCID:: PMC11160005

Abstract Article PDF–1.8M

Select item 1105041015.

Runx3 Regulates CD8⁺ T Cell Local Expansion and CD43 Glycosylation in Mice by H1N1 Influenza A Virus Infection

Qin Hao, Suman Kundu, Sreerama Shetty, Hua Tang

Int J Mol Sci. 2024 Apr; 25(8): 4220. Published online 2024 Apr 11. doi: 10.3390/ijms25084220

PMCID:: PMC11050410

Abstract Article PDF–3.0M

Select item 991399516.

RUNX3 in Stem Cell and Cancer Biology

Linda Shyue Huey Chuang, Junichi Matsuo, Daisuke Douchi, Nur Astiana Bte Mawan, Yoshiaki Ito

Cells. 2023 Feb; 12(3): 408. Published online 2023 Jan 25. doi: 10.3390/cells12030408

PMCID:: PMC9913995

Abstract Article PDF–2.2M

Select item 958625017.

Inducible general knockout of Runx3 profoundly reduces pulmonary cytotoxic CD8⁺ T cells with minimal effect on outcomes in mice following influenza infection

Qin Hao, Suman Kundu, Sreerama Shetty, Torry A. Tucker, Steven Idell, Hua Tang

Front Immunol. 2022; 13: 1011922. Published online 2022 Oct 7. doi: 10.3389/fimmu.2022.1011922

PMCID:: PMC9586250

Abstract Article PDF–14M

Select item 801015118.

Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells

Alexandra Franziska Gülich, Ramona Rica, Caroline Tizian, Csilla Viczenczova, Kseniya Khamina, Thomas Faux, Daniela Hainberger, Thomas Penz, Remy Bosselut, Christoph Bock, Asta Laiho, Laura L. Elo, Andreas Bergthaler, Wilfried Ellmeier, Shinya Sakaguchi

Front Immunol. 2021; 12: 535039. Published online 2021 Mar 17. doi: 10.3389/fimmu.2021.535039