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Select item 112211461.

Impact of aquaporin-4 and CD11c + microglia in the development of ependymal cells in the aqueduct: inferences to hydrocephalus

Francisco Mayo, Lourdes González-Vinceiro, Laura Hiraldo-González, Francisco D. Rodríguez-Gómez, Claudia Calle-Castillejo, Manuel Mayo, Vanina Netti, Reposo Ramírez-Lorca, Miriam Echevarría

Fluids Barriers CNS. 2024; 21: 53. Published online 2024 Jul 2. doi: 10.1186/s12987-024-00548-2

PMCID:: PMC11221146

Abstract Article PDF–11M

Select item 111312572.

NHH promotes Sepsis-associated Encephalopathy with the expression of AQP4 in astrocytes through the gut-brain Axis

Lina Zhao, Zhen Zhang, Pei Wang, Nannan Zhang, Hao shen, Hening Wu, Zhiyong Wei, Fei Yang, Yunying Wang, Zhijie Yu, Haibo Li, Zhanfei Hu, Hongyan Zhai, Zhiwei Wang, Fuhong Su, Keliang Xie, Yun Li

J Neuroinflammation. 2024; 21: 138. Published online 2024 May 27. doi: 10.1186/s12974-024-03135-2

PMCID:: PMC11131257

Abstract Article PDF–16M

Select item 109645593.

Role of aquaporin-4 polarization in extracellular solute clearance

Laura Bojarskaite, Sahar Nafari, Anne Katrine Ravnanger, Mina Martine Frey, Nadia Skauli, Knut Sindre Åbjørsbråten, Lena Catherine Roth, Mahmood Amiry-Moghaddam, Erlend A. Nagelhus, Ole Petter Ottersen, Inger Lise Bogen, Anna E. Thoren, Rune Enger

Fluids Barriers CNS. 2024; 21: 28. Published online 2024 Mar 26. doi: 10.1186/s12987-024-00527-7

PMCID:: PMC10964559

Abstract Article PDF–2.4M

Select item 109524784.

Deletion of aquaporin‐4 improves capillary blood flow distribution in brain edema

Luca Bordoni, Anna E. Thoren, Eugenio Gutiérrez‐Jiménez, Knut S. Åbjørsbråten, Daniel M. Bjørnstad, Wannan Tang, Mette Stern, Leif Østergaard, Erlend A. Nagelhus, Sebastian Frische, Ole P. Ottersen, Rune Enger

Glia. 2023 Nov; 71(11): 2559–2572. Published online 2023 Jul 13. doi: 10.1002/glia.24439

PMCID:: PMC10952478

Abstract Article PDF–5.3M

Select item 108482985.

Water channel aquaporin 4 is required for T cell receptor mediated lymphocyte activation

Michael Nicosia, Juyeun Lee, Ashley Beavers, Danielle Kish, George W. Farr, Paul R. McGuirk, Marc F. Pelletier, Justin D. Lathia, Robert L. Fairchild, Anna Valujskikh

J Leukoc Biol. Author manuscript; available in PMC 2024 Feb 7.

Published in final edited form as: J Leukoc Biol. 2023 Jun 1; 113(6): 544–554. doi: 10.1093/jleuko/qiad010

PMCID:: PMC10848298

Abstract Article PDF–2.0M

Select item 107015216.

Evaluation of gliovascular functions of AQP4 readthrough isoforms

Shayna M. Mueller, Kelli McFarland White, Stuart B. Fass, Siyu Chen, Zhan Shi, Xia Ge, John A. Engelbach, Seana H. Gaines, Annie R. Bice, Michael J. Vasek, Joel R. Garbow, Joseph P. Culver, Zila Martinez-Lozada, Martine Cohen-Salmon, Joseph D. Dougherty, Darshan Sapkota

Front Cell Neurosci. 2023; 17: 1272391. Published online 2023 Nov 23. doi: 10.3389/fncel.2023.1272391

PMCID:: PMC10701521

Abstract Article PDF–3.7M

Select item 104058507.

Preconditioned extracellular vesicles from hypoxic microglia reduce poststroke AQP4 depolarization, disturbed cerebrospinal fluid flow, astrogliosis, and neuroinflammation

Wenqiang Xin, Yongli Pan, Wei Wei, Lars Tatenhorst, Irina Graf, Aurel Popa-Wagner, Stefan T Gerner, Sabine Huber, Ertugrul Kilic, Dirk M Hermann, Mathias Bähr, Hagen B Huttner, Thorsten R Doeppner

Theranostics. 2023; 13(12): 4197–4216. Published online 2023 Jul 24. doi: 10.7150/thno.84059

PMCID:: PMC10405850

Abstract Article PDF–13M

Select item 104019338.

Evaluation of gliovascular functions of Aqp4 readthrough isoforms

Shayna M. Mueller, Kelli McFarland White, Stuart B. Fass, Siyu Chen, Zhan Shi, Xia Ge, John A. Engelbach, Seana H Gaines, Annie R Bice, Michael J. Vasek, Joel R. Garbow, Joseph P. Culver, Zila Martinez-Lozada, Martine Cohen-Salmon, Joseph D. Dougherty, Darshan Sapkota

Version 1. bioRxiv. Preprint. 2023 Jul 25. doi: 10.1101/2023.07.21.549379

Published in:: Front Cell Neurosci. 2023; 17: 1272391.

PMCID:: PMC10401933

Abstract Article PDF–38M

Select item 103913429.

Stimulated Raman scattering microscopy reveals a unique and steady nature of brain water dynamics

Takanori Shinotsuka, Tsuyoshi Miyazawa, Keiko Karasawa, Yasuyuki Ozeki, Masato Yasui, Mutsuo Nuriya

Cell Rep Methods. 2023 Jul 24; 3(7): 100519. Published online 2023 Jul 5. doi: 10.1016/j.crmeth.2023.100519

PMCID:: PMC10391342

Abstract Article PDF–7.4M

Select item 1023323410.

Aqp4 stop codon readthrough facilitates amyloid-β clearance from the brain

Darshan Sapkota, Colin Florian, Brookelyn M Doherty, Kelli M White, Kate M Reardon, Xia Ge, Joel R Garbow, Carla M Yuede, John R Cirrito, Joseph D Dougherty

Brain. 2022 Sep; 145(9): 2982–2990. Published online 2022 Aug 18. doi: 10.1093/brain/awac199

PMCID:: PMC10233234

Abstract Article PDF–1.2M

Select item 999511311.

Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

Ryszard Stefan Gomolka, Lauren M Hablitz, Humberto Mestre, Michael Giannetto, Ting Du, Natalie Linea Hauglund, Lulu Xie, Weiguo Peng, Paula Melero Martinez, Maiken Nedergaard, Yuki Mori

eLife. 2023; 12: e82232. Published online 2023 Feb 9. doi: 10.7554/eLife.82232

PMCID:: PMC9995113

Abstract Article PDF–6.0M

Select item 986546212.

Assessing the Role of Aquaporin 4 in Skeletal Muscle Function

Tejal Aslesh, Ammar Al-aghbari, Toshifumi Yokota

Int J Mol Sci. 2023 Jan; 24(2): 1489. Published online 2023 Jan 12. doi: 10.3390/ijms24021489

PMCID:: PMC9865462

Abstract Article PDF–708K

Select item 985055513.

Sleep fragmentation affects glymphatic system through the different expression of AQP4 in wild type and 5xFAD mouse models

Valeria Vasciaveo, Antonella Iadarola, Antonino Casile, Davide Dante, Giulia Morello, Lorenzo Minotta, Elena Tamagno, Alessandro Cicolin, Michela Guglielmotto

Acta Neuropathol Commun. 2023; 11: 16. Published online 2023 Jan 18. doi: 10.1186/s40478-022-01498-2

PMCID:: PMC9850555

Abstract Article PDF–3.8M

Select item 963700114.

AQP4-A25Q Point Mutation in Mice Depolymerizes Orthogonal Arrays of Particles and Decreases Polarized Expression of AQP4 Protein in Astrocytic Endfeet at the Blood–Brain Barrier

Dan-Dan Zhu, Guang Yang, Yue-Lin Huang, Ting Zhang, Ao-Ran Sui, Na Li, Wei-Heng Su, Hai-Lun Sun, Jing-Jing Gao, Michael Ntim, Rong-Xiao Guan, Ling-Ling Jin, Jian Yu, Zhi-Yong Huang, Tong-Hui Ma, Shao Li

J Neurosci. 2022 Oct 26; 42(43): 8169–8183. doi: 10.1523/JNEUROSCI.0401-22.2022

PMCID:: PMC9637001

Abstract Article PDF–7.2M

Select item 916688015.

Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation

Ali Maisam Afzali, Lasse Stüve, Monika Pfaller, Lilian Aly, Katja Steiger, Benjamin Knier, Thomas Korn

J Mol Med (Berl) 2022; 100(6): 933–946. Published online 2022 May 10. doi: 10.1007/s00109-022-02202-6

PMCID:: PMC9166880

Abstract Article PDF–2.7M

Select item 904029116.

Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice

Matthew Simon, Marie Xun Wang, Ozama Ismail, Molly Braun, Abigail G. Schindler, Jesica Reemmer, Zhongya Wang, Mariya A. Haveliwala, Ryan P. O’Boyle, Warren Y. Han, Natalie Roese, Marjorie Grafe, Randall Woltjer, Detlev Boison, Jeffrey J. Iliff

Alzheimers Res Ther. 2022; 14: 59. Published online 2022 Apr 26. doi: 10.1186/s13195-022-00999-5

PMCID:: PMC9040291

Abstract Article PDF–11M

Select item 849486917.

Exploring cell membrane water exchange in aquaporin-4-deficient ischemic mouse brain using diffusion-weighted MRI

Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Yasuhiko Tachibana, Nobuhiro Nitta, Sayaka Shibata, Masato Yasui, Makoto Higuchi, Takayuki Obata

Eur Radiol Exp. 2021 Dec; 5: 44. Published online 2021 Oct 7. doi: 10.1186/s41747-021-00244-y

PMCID:: PMC8494869

Abstract Article PDF–1.4M

Select item 847114218.

Aquaporin-4 Mediates Permanent Brain Alterations in a Mouse Model of Hypoxia-Aged Hydrocephalus

José Luis Trillo-Contreras, Juan José Toledo-Aral, Javier Villadiego, Miriam Echevarría

Int J Mol Sci. 2021 Sep; 22(18): 9745. Published online 2021 Sep 9. doi: 10.3390/ijms22189745

PMCID:: PMC8471142

Abstract Article PDF–3.6M

Select item 841852919.

Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice

Daniel C. Lu, Zsolt Zador, Jinghua Yao, Farbod Fazlollahi, Geoffrey T. Manley

J Neurotrauma. April 15, 2021; 38(8): 1193–1201. Published online 2021 Apr 5. doi: 10.1089/neu.2011.2114

PMCID:: PMC8418529

Abstract Article PDF–850K

Select item 836169620.

Regulation of aquaporin‐4 expression in the central nervous system investigated using M23‐AQP4 null mouse

Francesco Pisani, Laura Simone, Maria Grazia Mola, Manuela De Bellis, Antonio Frigeri, Grazia Paola Nicchia, Maria Svelto

Glia. 2021 Sep; 69(9): 2235–2251. Published online 2021 May 26. doi: 10.1002/glia.24032

PMCID:: PMC8361696

Abstract Article PDF–4.9M

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PMC Links for Gene (Select 11829) (229)
PMC
PREDICTED: Panicum hallii alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosa...
PREDICTED: Panicum hallii alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (LOC112888575), transcript variant X8, mRNA
gi|1435114255|ref|XM_025954861.1|

Nucleotide
Mus musculus 7 days neonate cerebellum cDNA, RIKEN full-length enriched library,...
Mus musculus 7 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:A730071F09 product:hypothetical protein, full insert sequence
gi|26335588|dbj|AK043214.1|

Nucleotide
Homo sapiens Chromosome 4p16.3 BAC clone 399e10 containing Huntington's Disease ...
Homo sapiens Chromosome 4p16.3 BAC clone 399e10 containing Huntington's Disease gene; exons 1-67, complete sequence
gi|3900835|gnl|utswmed|BAC399e10|gb 5516.1|AC005516

Nucleotide

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