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Select item 56274831.

CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathway

Xiaofen Li, Wangxiong Hu, Jiaojiao Zhou, Yanqin Huang, Jiaping Peng, Ying Yuan, Jiekai Yu, Shu Zheng

Cell Commun Signal. 2017; 15: 38. Published online 2017 Oct 3. doi: 10.1186/s12964-017-0192-z

PMCID:: PMC5627483

Abstract Article PDF–2.2M

Select item 46543322.

Low Expression of Chloride Channel Accessory 1 Predicts a Poor Prognosis in Colorectal Cancer

Bo Yang, Lin Cao, Jiaen Liu, Yanjie Xu, Gillian Milne, Wanhei Chan, Steven D Heys, Colin D McCaig, Jin Pu

Cancer. 2015 May 15; 121(10): 1570–1580. Published online 2015 Jan 20. doi: 10.1002/cncr.29235

PMCID:: PMC4654332

Abstract Article PDF–542K

Select item 44980613.

Comparative Proteomics of Ovarian Cancer Aggregate Formation Reveals an Increased Expression of Calcium-activated Chloride Channel Regulator 1 (CLCA1)

Natasha Musrap, Alessandra Tuccitto, George S. Karagiannis, Punit Saraon, Ihor Batruch, Eleftherios P. Diamandis

J Biol Chem. 2015 Jul 10; 290(28): 17218–17227. Published online 2015 May 24. doi: 10.1074/jbc.M115.639773

PMCID:: PMC4498061

Abstract Article PDF–1.1M

Select item 38614824.

Secreted hCLCA1 Is a Signaling Molecule That Activates Airway Macrophages

John C. H. Ching, Liubov Lobanova, Matthew E. Loewen

PLoS One. 2013; 8(12): e83130. Published online 2013 Dec 12. doi: 10.1371/journal.pone.0083130

PMCID:: PMC3861482

Abstract Article PDF–2.8M

Select item 36251865.

The Transition from Proliferation to Differentiation in Colorectal Cancer Is Regulated by the Calcium Activated Chloride Channel A1

Bo Yang, Lin Cao, Bin Liu, Colin D. McCaig, Jin Pu

PLoS One. 2013; 8(4): e60861. Published online 2013 Apr 12. doi: 10.1371/journal.pone.0060861

PMCID:: PMC3625186

Abstract Article PDF–5.3M

Select item 34896976.

Increased human Ca²⁺-activated Cl^- channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients

Hiroki Iwashita, Keisaku Fujimoto, Shigeru Morita, Atsushi Nakanishi, Keishi Kubo

Respir Res. 2012; 13(1): 55. Published online 2012 Jun 25. doi: 10.1186/1465-9921-13-55

PMCID:: PMC3489697

Abstract Article PDF–1.4M

Select item 26919037.

Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents

Martine Hamann, Adele Gibson, Noel Davies, Amanda Jowett, Jean Philippe Walhin, Leanne Partington, Karen Affleck, Derek Trezise, Martin Main

J Physiol. 2009 May 15; 587(Pt 10): 2255–2274. Published online 2009 Mar 23. doi: 10.1113/jphysiol.2009.170159

PMCID:: PMC2691903

Abstract Article PDF–865K

Select item 70504728.

Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement

Kayla N. Berry, Tom J. Brett

Cell Rep. Author manuscript; available in PMC 2020 Mar 2.

Published in final edited form as: Cell Rep. 2020 Jan 28; 30(4): 1141–1151.e3. Published online 2020 Jan 28. doi: 10.1016/j.celrep.2019.12.059

PMCID:: PMC7050472

Abstract Article PDF–2.2M

Select item 60855409.

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity

Elisabeth E.L. Nyström, George M.H. Birchenough, Sjoerd van der Post, Liisa Arike, Achim D. Gruber, Gunnar C. Hansson, Malin E.V. Johansson

EBioMedicine. 2018 Jul; 33: 134–143. Published online 2018 Jun 7. doi: 10.1016/j.ebiom.2018.05.031

PMCID:: PMC6085540

Abstract Article PDF–2.3M

Select item 545409910.

Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1)

Monica Sala-Rabanal, Zeynep Yurtsever, Kayla N. Berry, Colin G. Nichols, Tom J. Brett

J Biol Chem. 2017 Jun 2; 292(22): 9164–9174. Published online 2017 Apr 18. doi: 10.1074/jbc.M117.788232

PMCID:: PMC5454099

Abstract Article PDF–2.2M

Select item 436065311.

Secreted CLCA1 modulates TMEM16A to activate Ca²⁺-dependent chloride currents in human cells

Monica Sala-Rabanal, Zeynep Yurtsever, Colin G Nichols, Tom J Brett

eLife. 2015; 4: e05875. Published online 2015 Mar 17. doi: 10.7554/eLife.05875

PMCID:: PMC4360653

Abstract Article PDF–2.8M

Select item 351675912.

Self-cleavage of Human CLCA1 Protein by a Novel Internal Metalloprotease Domain Controls Calcium-activated Chloride Channel Activation

Zeynep Yurtsever, Monica Sala-Rabanal, David T. Randolph, Suzanne M. Scheaffer, William T. Roswit, Yael G. Alevy, Anand C. Patel, Richard F. Heier, Arthur G. Romero, Colin G. Nichols, Michael J. Holtzman, Tom J. Brett

J Biol Chem. 2012 Dec 7; 287(50): 42138–42149. Published online 2012 Oct 30. doi: 10.1074/jbc.M112.410282

PMCID:: PMC3516759

Abstract Article PDF–4.3M

Select item 200042713.

Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

Prescott G. Woodruff, Homer A. Boushey, Gregory M. Dolganov, Chris S. Barker, Yee Hwa Yang, Samantha Donnelly, Almut Ellwanger, Sukhvinder S. Sidhu, Trang P. Dao-Pick, Carlos Pantoja, David J. Erle, Keith R. Yamamoto, John V. Fahy

Proc Natl Acad Sci U S A. 2007 Oct 2; 104(40): 15858–15863. Published online 2007 Sep 26. doi: 10.1073/pnas.0707413104

PMCID:: PMC2000427

Abstract Article PDF–305K

Select item 173570314.

CLCA1 gene polymorphisms in chronic obstructive pulmonary disease

A Hegab, T Sakamoto, Y Uchida, A Nomura, Y Ishii, Y Morishima, M Mochizuki, T Kimura, W Saitoh, H Massoud, H Massoud, K Hassanein, K Sekizawa

J Med Genet. 2004 Mar; 41(3): e27. doi: 10.1136/jmg.2003.012484

PMCID:: PMC1735703

Summary PDF–284K

Select item 1100374315.

Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

Preksha Gaur, Yesheswini Rajendran, Bhagyashree Srivastava, Manasvini Markandey, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Aamir Suhail, Shikha Chaudhary, Shaifali Tyagi, Subhash Chandra Yadav, Amit Kumar Pandey, Yifat Merbl, Avinash Bajaj, Vineet Ahuja, Chittur Srikanth

eLife. 2024; 12: RP89776. Published online 2024 Apr 9. doi: 10.7554/eLife.89776

PMCID:: PMC11003743

Abstract Article PDF–11M

Select item 685130016.

Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2–processing properties

Elisabeth E. L. Nyström, Liisa Arike, Erik Ehrencrona, Gunnar C. Hansson, Malin E. V. Johansson

J Biol Chem. 2019 Nov 8; 294(45): 17075–17089. Published online 2019 Sep 29. doi: 10.1074/jbc.RA119.009940

PMCID:: PMC6851300

Abstract Article PDF–3.1M

Select item 1831817.

HIV-1 gp120 and chemokines activate ion channels in primary macrophages through CCR5 and CXCR4 stimulation

Qing-Hua Liu, Darlisha A. Williams, Carrie McManus, Frédéric Baribaud, Robert W. Doms, Dominique Schols, Erik De Clercq, Michael I. Kotlikoff, Ronald G. Collman, Bruce D. Freedman

Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9): 4832–4837. Published online 2000 Apr 11. doi: 10.1073/pnas.090521697

PMCID:: PMC18318

Abstract Article PDF–128K

Select item 313914718.

HIV-1 Envelope Glycoprotein Biosynthesis, Trafficking, and Incorporation

Mary Ann Checkley, Benjamin G. Luttge, Eric O. Freed

J Mol Biol. Author manuscript; available in PMC 2012 Jul 22.

Published in final edited form as: J Mol Biol. 2011 Jul 22; 410(4): 582–608. doi: 10.1016/j.jmb.2011.04.042

PMCID:: PMC3139147

Abstract Article PDF–2.3M

Select item 275281119.

Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging

Heather E. Wheeler, E. Jeffrey Metter, Toshiko Tanaka, Devin Absher, John Higgins, Jacob M. Zahn, Julie Wilhelmy, Ronald W. Davis, Andrew Singleton, Richard M. Myers, Luigi Ferrucci, Stuart K. Kim

PLoS Genet. 2009 Oct; 5(10): e1000685. Published online 2009 Oct 16. doi: 10.1371/journal.pgen.1000685

PMCID:: PMC2752811

Abstract Article PDF–409K

Select item 296777020.

Polymorphisms in innate immunity genes and risk of childhood leukemia

Sohee Han, Qing Lan, Ae Kyung Park, Kyoung-Mu Lee, Sue K. Park, Hyo Seop Ahn, Hee Young Shin, Hyoung Jin Kang, Hong Hoe Koo, Jong Jin Seo, Ji Eun Choi, Yoon-Ok Ahn, Stephen J. Chanock, Ho Kim, Nathaniel Rothman, Daehee Kang

Hum Immunol. Author manuscript; available in PMC 2010 Nov 2.

Published in final edited form as: Hum Immunol. 2010 Jul; 71(7): 727–730. Published online 2010 May 16. doi: 10.1016/j.humimm.2010.04.004

PMCID:: PMC2967770

Abstract Article PDF–306K

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Rattus norvegicus ribosomal protein S20 (Rps20), mRNA
Rattus norvegicus ribosomal protein S20 (Rps20), mRNA
gi|56090270|ref|NM_001007603.1|

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