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Items: 1 to 20 of 1221

1.
Dual roles of myocardial mitochondrial AKT on diabetic cardiomyopathy and whole body metabolism
Yu-Han Chen, Albert P. Ta, Yumay Chen, Hsiao-Chen Lee, Wenjun Fan, Phang-Lang Chen, Maria C. Jordan, Kenneth P. Roos, Grant R. MacGregor, Qin Yang, Robert A. Edwards, Junfeng Li, Ping H. Wang
Cardiovasc Diabetol. 2023; 22: 294. Published online 2023 Oct 27. doi: 10.1186/s12933-023-02020-1
PMCID:
PMC10612246
AbstractArticlePDF–7.7M
2.
Decrotonylation of AKT1 promotes AKT1 phosphorylation and activation during myogenic differentiation
Zhengyu Qian, Jingwei Ye, Jinteng Li, Yunshu Che, Wenhui Yu, Peitao Xu, Jiajie Lin, Feng Ye, Xiaojun Xu, Zepeng Su, Dateng Li, Zhongyu Xie, Yanfeng Wu, Huiyong Shen
J Adv Res. 2023 Aug; 50: 117–133. Published online 2022 Oct 18. doi: 10.1016/j.jare.2022.10.005
PMCID:
PMC10403674
AbstractArticlePDF–5.2M
3.
Akt1-dependent expression of angiopoietin 1 and 2 in vascular smooth muscle cells leads to vascular stabilization
Jung Min Ha, Seo Yeon Jin, Hye Sun Lee, Hye Jin Kum, Farzaneh Vafaeinik, Hong Koo Ha, Sang Heon Song, Chi Dae Kim, Sun Sik Bae
Exp Mol Med. 2022 Aug; 54(8): 1133–1145. Published online 2022 Aug 5. doi: 10.1038/s12276-022-00819-8
PMCID:
PMC9440121
AbstractArticlePDF–9.1M
4.
Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells
Xiaoqing Dong, Rui Zhao, Yue Li, Qianyun Yu, Xin Chen, Xiaoyu Hu, Jing Ma, Xiaoling Chen, Shile Huang, Long Chen
Int J Biochem Cell Biol. Author manuscript; available in PMC 2022 Jun 8.
Published in final edited form as: Int J Biochem Cell Biol. 2019 Sep; 114: 105573. Published online 2019 Jul 17. doi: 10.1016/j.biocel.2019.105573
PMCID:
PMC9175263
AbstractArticlePDF–1.9M
5.
Activation of Akt–mTORC1 signalling reverts cancer‐dependent muscle wasting
Alessia Geremia, Roberta Sartori, Martina Baraldo, Leonardo Nogara, Valeria Balmaceda, Georgia Ana Dumitras, Stefano Ciciliot, Marco Scalabrin, Hendrik Nolte, Bert Blaauw
J Cachexia Sarcopenia Muscle. 2022 Feb; 13(1): 648–661. Published online 2021 Nov 6. doi: 10.1002/jcsm.12854
PMCID:
PMC8818597
AbstractArticlePDF–3.0M
6.
Regulation of AKT Signaling in Mouse Uterus
Vijay K Sirohi, Theresa I Medrano, Ana M Mesa, Athilakshmi Kannan, Indrani C Bagchi, Paul S Cooke
Endocrinology. 2022 Jan; 163(1): bqab233. Published online 2021 Nov 17. doi: 10.1210/endocr/bqab233
PMCID:
PMC8667855
AbstractArticle
7.
Prophylactic treatment with BX795 blocks activation of AKT and its downstream targets to protect vaginal keratinocytes and vaginal epithelium from HSV-2 infection
Krishnaraju Madavaraju, Tejabhiram Yadavalli, Sudhanshu Kumar Singh, Farreh Qatanani, Deepak Shukla
Antiviral Res. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Antiviral Res. 2021 Oct; 194: 105145. Published online 2021 Jul 22. doi: 10.1016/j.antiviral.2021.105145
PMCID:
PMC8446323
AbstractArticlePDF–1.9M
8.
Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease
Il Young Kim, Yeon Kyeong Park, Sang Heon Song, Eun Young Seong, Dong Won Lee, Sun Sik Bae, Soo Bong Lee
Korean J Intern Med. 2021 Jul; 36(4): 962–974. Published online 2020 Dec 16. doi: 10.3904/kjim.2020.198
PMCID:
PMC8273823
AbstractArticlePDF–4.3M
9.
The kinase AKT1 potentiates the suppressive functions of myeloid-derived suppressor cells in inflammation and cancer
Anna Jia, Yuexin Wang, Yufei Wang, Yan Li, Qiuli Yang, Yejin Cao, Ying He, Lin Dong, Yingjie Dong, Yueru Hou, Ruoning Wang, Yujing Bi, Guangwei Liu
Cell Mol Immunol. 2021 Apr; 18(4): 1074–1076. Published online 2021 Jan 18. doi: 10.1038/s41423-020-00610-7
PMCID:
PMC8115558
ArticlePDF–1.0M
10.
Akt Is S-Palmitoylated: A New Layer of Regulation for Akt
Matías Blaustein, Estefanía Piegari, Camila Martínez Calejman, Antonella Vila, Analía Amante, María Victoria Manese, Ari Zeida, Laurence Abrami, Mariela Veggetti, David A. Guertin, F. Gisou van der Goot, María Martha Corvi, Alejandro Colman-Lerner
Front Cell Dev Biol. 2021; 9: 626404. Published online 2021 Feb 15. doi: 10.3389/fcell.2021.626404
PMCID:
PMC7917195
AbstractArticlePDF–3.4M
11.
Energy Metabolism During Osteogenic Differentiation: The Role of Akt
Charles Owen Smith, Roman A. Eliseev
Stem Cells Dev. February 2021; 30(3): 149–162. Published online 2021 Jan 27. doi: 10.1089/scd.2020.0141
PMCID:
PMC7876359
AbstractArticlePDF–1.1M
12.
Deletion of Akt1 Promotes Kidney Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
Il Young Kim, Min Young Lee, Mi Wha Park, Eun Young Seong, Dong Won Lee, Soo Bong Lee, Sun Sik Bae, Sang Soo Kim, Sang Heon Song
Biomed Res Int. 2020; 2020: 6143542. Published online 2020 Nov 24. doi: 10.1155/2020/6143542
PMCID:
PMC7707954
AbstractArticlePDF–8.8M
13.
Transient activation of mTORC1 signaling in skeletal muscle is independent of Akt1 regulation
Mitsunori Miyazaki, Nobuki Moriya, Tohru Takemasa
Physiol Rep. 2020 Oct; 8(19): e14599. Published online 2020 Oct 10. doi: 10.14814/phy2.14599
PMCID:
PMC7547586
AbstractArticlePDF–691K
14.
AKT1 Regulates Endoplasmic Reticulum Stress and Mediates the Adaptive Response of Pancreatic β Cells
Zhechu Peng, Richa Aggarwal, Ni Zeng, Lina He, Eileen X. Stiles, Anketse Debebe, Jingyu Chen, Chien-Yu Chen, Bangyan L. Stiles
Mol Cell Biol. 2020 Jun; 40(11): e00031-20. Prepublished online 2020 Mar 16. Published online 2020 May 14. doi: 10.1128/MCB.00031-20
PMCID:
PMC7225563
AbstractArticlePDF–4.8M
15.
Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
Md. Razaul Karim, Cody R. Fisher, Rebecca J. Kapphahn, Jorge R. Polanco, Deborah A. Ferrington
PLoS One. 2020; 15(4): e0231212. Published online 2020 Apr 10. doi: 10.1371/journal.pone.0231212
PMCID:
PMC7147741
AbstractArticlePDF–2.9M
16.
Lithium for schizophrenia: supporting evidence from a 12-year, nationwide health insurance database and from Akt1-deficient mouse and cellular models
Da-Zhong Luo, Chia-Yuan Chang, Tsung-Ren Huang, Vincent Studer, Tsu-Wei Wang, Wen-Sung Lai
Sci Rep. 2020; 10: 647. Published online 2020 Jan 20. doi: 10.1038/s41598-019-57340-8
PMCID:
PMC6971245
AbstractArticlePDF–2.9M
17.
Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages
Yunjuan Nie, Yudong Hu, Kaikai Yu, Dan Zhang, Yinze Shi, Yaolin Li, Lei Sun, Feng Qian
Innate Immun. 2019 Oct; 25(7): 451–461. Published online 2019 Jul 12. doi: 10.1177/1753425919861774
PMCID:
PMC6900639
AbstractArticlePDF–1.3M
18.
Dopamine Induces a PI3-Kinase-Independent Activation of Akt in Striatal Neurons: A New Route to cAMP Response Element-Binding Protein Phosphorylation
Karen Brami-Cherrier, Emmanuel Valjent, Marta Garcia, Christiane Pagès, Robert A. Hipskind, Jocelyne Caboche
J Neurosci. 2002 Oct 15; 22(20): 8911–8921. doi: 10.1523/JNEUROSCI.22-20-08911.2002
PMCID:
PMC6757682
AbstractArticlePDF–667K
19.
Akt-1 Expression Level Regulates CNS Precursors
Amy D. Sinor, Laura Lillien
J Neurosci. 2004 Sep 29; 24(39): 8531–8541. doi: 10.1523/JNEUROSCI.1470-04.2004
PMCID:
PMC6729906
AbstractArticlePDF–563K
20.
Akt1-mediated CPR cooling protection targets regulators of metabolism, inflammation and contractile function in mouse cardiac arrest
Jing Li, Xiangdong Zhu, Huashan Wang, Chunpei Lee, Sy-Jou Chen, Yuanyu Qian, Mei Han, Ryan Bunney, David G. Beiser, Terry L. Vanden Hoek
PLoS One. 2019; 14(8): e0220604. Published online 2019 Aug 9. doi: 10.1371/journal.pone.0220604
PMCID:
PMC6688812
AbstractArticlePDF–2.2M

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