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Select item 105879701.

RCC1 functions as a tumor facilitator in clear cell renal cell carcinoma by dysregulating cell cycle, apoptosis, and EZH2 stability

Yunfei Wu, Zhijie Xu, Xiaoyi Chen, Guanghou Fu, Junjie Tian, Baiye Jin

Cancer Med. 2023 Oct; 12(19): 19889–19903. Published online 2023 Sep 25. doi: 10.1002/cam4.6594

PMCID:: PMC10587970

Abstract Article PDF–31M

Select item 86741892.

RCC1 Expression as a Prognostic Marker in Colorectal Liver Oligometastases

Yuxiang Deng, Long Yu, Yujie Zhao, Jianhong Peng, Yanbo Xu, JiaYi Qin, Binyi Xiao, Songran Liu, Mei Li, Yujing Fang, Zhizhong Pan

Pathol Oncol Res. 2021; 27: 1610077. Published online 2021 Dec 2. doi: 10.3389/pore.2021.1610077

PMCID:: PMC8674189

Abstract Article PDF–2.0M

Select item 80517083.

Down‐regulation of RCC1 sensitizes immunotherapy by up‐regulating PD‐L1 via p27^kip1/CDK4 axis in non‐small cell lung cancer

Xiaozhu Zeng, Maoxi Zhong, Yumeng Yang, Zhi Wang, Yuxi Zhu

J Cell Mol Med. 2021 Apr; 25(8): 4136–4147. Published online 2021 Feb 25. doi: 10.1111/jcmm.16383

PMCID:: PMC8051708

Abstract Article PDF–2.4M

Select item 59695424.

RCC1 regulates inner centromeric composition in a Ran-independent fashion

Michael Shaofei Zhang, Maiko Furuta, Alexei Arnaoutov, Mary Dasso

Cell Cycle. 2018; 17(6): 739–748. Published online 2018 Apr 5. doi: 10.1080/15384101.2018.1442630

PMCID:: PMC5969542

Abstract Article PDF–1.3M

Select item 47135285.

Methylation-silencing RCC1 expression is associated with tumorigenesis and depth of invasion in gastric cancer

Yi-Ling Lin, Hsiao-Ling Chen, Shao-Bin Cheng, Dah-Cherng Yeh, Chu-Chun Huang, Fang-Ku P’eng, Tung-Chou Tsai, Cheng-Chung Wu, Chuan-Mu Chen

Int J Clin Exp Pathol. 2015; 8(11): 14257–14269. Published online 2015 Nov 1.

PMCID:: PMC4713528

Abstract Article PDF–1.2M

Select item 35899886.

Linkage to Chromosome 1p36 for Attention Deficit Hyperactivity Disorder Traits in School and Home Settings

Kaixin Zhou, Philip Asherson, Pak Sham, Barbara Franke, Richard JL Anney, Jan Buitelaar, Richard Ebstein, Michael Gill, Keeley Brookes, Cathelijne Buschgens, Desmond Campbell, Wai Chen, Hanna Christiansen, Ellen Fliers, Isabel Gabriëls, Lena Johansson, Rafaela Marco, Fernando Mulas, Ueli Müller, Aisling Mulligan, Benjamin M. Neale, Fruhling Rijsdijk, Nanda Rommelse, Henrik Uebel, Lamprini Psychogiou, Xiaohui Xu, Tobias Banaschewski, Edmund Sonuga-Barke, Jacques Eisenberg, Iris Manor, Ana Miranda, Robert D. Oades, Herbert Roeyers, Aribert Rothenberger, Joseph Sergeant, Hans-Christoph Steinhausen, Eric Taylor, Margaret Thompson, Stephen V Faraone

Biol Psychiatry. Author manuscript; available in PMC 2013 Mar 6.

Published in final edited form as: Biol Psychiatry. 2008 Oct 1; 64(7): 571–576. Published online 2008 Apr 24. doi: 10.1016/j.biopsych.2008.02.024

PMCID:: PMC3589988

Abstract Article PDF–791K

Select item 32464547.

Mitotic Spindle Assembly around RCC1-Coated Beads in Xenopus Egg Extracts

David Halpin, Petr Kalab, Jay Wang, Karsten Weis, Rebecca Heald

PLoS Biol. 2011 Dec; 9(12): e1001225. Published online 2011 Dec 27. doi: 10.1371/journal.pbio.1001225

PMCID:: PMC3246454

Abstract Article PDF–583K

Select item 25285828.

Regulation of chromatin binding by a conformational switch in the tail of the Ran exchange factor RCC1

Yi Hao, Ian G. Macara

J Cell Biol. 2008 Sep 8; 182(5): 827–836. doi: 10.1083/jcb.200803110

PMCID:: PMC2528582

Abstract Article PDF–2.3M

Select item 21745749.

Nuclear Import of the Ran Exchange Factor, Rcc1, Is Mediated by at Least Two Distinct Mechanisms

Michael E. Nemergut, Ian G. Macara

J Cell Biol. 2000 May 15; 149(4): 835–850. doi: 10.1083/jcb.149.4.835

PMCID:: PMC2174574

Abstract Article PDF–615K

Select item 30754410.

The Dynamic Association of RCC1 with Chromatin Is Modulated by Ran-dependent Nuclear Transport

Ian Cushman, David Stenoien, Mary Shannon Moore

Mol Biol Cell. 2004 Jan; 15(1): 245–255. doi: 10.1091/mbc.E03-06-0409

PMCID:: PMC307544

Abstract Article PDF–680K

Select item 5500811.

A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation.

F R Bischoff, G Maier, G Tilz, H Ponstingl

Proc Natl Acad Sci U S A. 1990 Nov; 87(21): 8617–8621. doi: 10.1073/pnas.87.21.8617

PMCID:: PMC55008

Summary Page Browse PDF–1.2M

Select item 1098509112.

Targeting RCC1 to block the human soft-tissue sarcoma by disrupting nucleo-cytoplasmic trafficking of Skp2

Mingzhi Zhuang, Fengyue Li, Hong Liang, Yongfu Su, Lei Cheng, Bingkai Lin, Jun Zhou, Runzhi Deng, Linying Chen, Peng Lyu, Zhonglei Lu

Cell Death Dis. 2024 Apr; 15(4): 241. Published online 2024 Apr 1. doi: 10.1038/s41419-024-06629-2

PMCID:: PMC10985091

Abstract Article PDF–5.3M

Select item 830194613.

Phosphorylation of RCC1 on Serine 11 Facilitates G1/S Transition in HPV E7-Expressing Cells

Xiaoyan Hou, Lijun Qiao, Ruijuan Liu, Xuechao Han, Weifang Zhang

Biomolecules. 2021 Jul; 11(7): 995. Published online 2021 Jul 6. doi: 10.3390/biom11070995

PMCID:: PMC8301946

Abstract Article PDF–3.4M

Select item 797950914.

PRMT6 Methylation of RCC1 Regulates Mitosis, Tumorigenicity, and Radiation Response of Glioblastoma Stem Cells

Tianzhi Huang, Yongyong Yang, Xiao Song, Xuechao Wan, Bingli Wu, Namratha Sastry, Craig M. Horbinski, Chang Zeng, Deanna Tiek, Anshika Goenka, Fabao Liu, Cameron W. Brennan, John A. Kessler, Roger Stupp, Ichiro Nakano, Erik P. Sulman, Ryo Nishikawa, Charles David James, Wei Zhang, Wei Xu, Bo Hu, Shi-Yuan Cheng

Mol Cell. Author manuscript; available in PMC 2022 Mar 18.

Published in final edited form as: Mol Cell. 2021 Mar 18; 81(6): 1276–1291.e9. Published online 2021 Feb 3. doi: 10.1016/j.molcel.2021.01.015

PMCID:: PMC7979509

Abstract Article PDF–3.6M

Select item 746966215.

RanBP1 controls the Ran pathway in mammalian cells through regulation of mitotic RCC1 dynamics

Ka Chun Yau, Alexei Arnaoutov, Vasilisa Aksenova, Ross Kaufhold, Shane Chen, Mary Dasso

Cell Cycle. 2020; 19(15): 1899–1916. Published online 2020 Jun 28. doi: 10.1080/15384101.2020.1782036

PMCID:: PMC7469662

Abstract Article PDF–3.7M

Select item 596411316.

Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells

Lijun Qiao, Jingyi Zheng, Yonghao Tian, Qishu Zhang, Xiao Wang, Jason J. Chen, Weifang Zhang

Cell Death Dis. 2018 Jun; 9(6): 583. Published online 2018 May 22. doi: 10.1038/s41419-018-0584-z

PMCID:: PMC5964113

Abstract Article PDF–2.0M

Select item 564546717.

Three-dimensional context rather than NLS amino acid sequence determines importin α subtype specificity for RCC1

Rajeshwer S. Sankhala, Ravi K. Lokareddy, Salma Begum, Ruth A. Pumroy, Richard E. Gillilan, Gino Cingolani

Nat Commun. 2017; 8: 979. Published online 2017 Oct 17. doi: 10.1038/s41467-017-01057-7

PMCID:: PMC5645467

Abstract Article PDF–3.3M

Select item 483188718.

RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage–induced cell senescence

Pavol Cekan, Keisuke Hasegawa, Yu Pan, Emily Tubman, David Odde, Jin-Qiu Chen, Michelle A. Herrmann, Sheetal Kumar, Petr Kalab

Mol Biol Cell. 2016 Apr 15; 27(8): 1346–1357. doi: 10.1091/mbc.E16-01-0025

PMCID:: PMC4831887

Abstract Article PDF–1.8M

Select item 462427919.

N-terminal a-methylation of RCC1 is necessary for stable chromatin association and normal mitosis

Ting Chen, Tara L. Muratore, Christine E. Schaner-Tooley, Jeffrey Shabanowitz, Donald F. Hunt, Ian G. Macara

Nat Cell Biol. Author manuscript; available in PMC 2015 Oct 28.

Published in final edited form as: Nat Cell Biol. 2007 May; 9(5): 596–603. Published online 2007 Apr 15. doi: 10.1038/ncb1572

PMCID:: PMC4624279

Abstract Article PDF–1.5M

Select item 428542720.

Disruption of the Ran System by Cysteine Oxidation of the Nucleotide Exchange Factor RCC1

Mandovi Chatterjee, Bryce M. Paschal

Mol Cell Biol. 2015 Feb; 35(3): 566–581. Prepublished online 2014 Dec 1. Published online 2015 Jan 7. doi: 10.1128/MCB.01133-14

PMCID:: PMC4285427

Abstract Article PDF–4.6M

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