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Select item 112009331.

Deletion of Glyoxalase 1 Exacerbates Acetaminophen-Induced Hepatotoxicity in Mice

Prakashkumar Dobariya, Wei Xie, Swetha Pavani Rao, Jiashu Xie, Davis M. Seelig, Robert Vince, Michael K. Lee, Swati S. More

Antioxidants (Basel) 2024 Jun; 13(6): 648. Published online 2024 May 25. doi: 10.3390/antiox13060648

PMCID:: PMC11200933

Abstract Article PDF–8.1M

Select item 92537542.

Glyoxalase 1 knockdown induces age‐related β‐cell dysfunction and glucose intolerance in mice

Immacolata Prevenzano, Alessia Leone, Michele Longo, Antonella Nicolò, Serena Cabaro, Francesca Collina, Iacopo Panarese, Gerardo Botti, Pietro Formisano, Raffaele Napoli, Francesco Beguinot, Claudia Miele, Cecilia Nigro

EMBO Rep. 2022 Jul; 23(7): e52990. Published online 2022 May 27. doi: 10.15252/embr.202152990

PMCID:: PMC9253754

Abstract Article PDF–2.1M

Select item 82539143.

Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex

Kazuya Toriumi, Stefano Berto, Shin Koike, Noriyoshi Usui, Takashi Dan, Kazuhiro Suzuki, Mitsuhiro Miyashita, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Kenichiro Nagahama, Hsiao-Chun Lin, Yuki Sugaya, Takaki Watanabe, Masanobu Kano, Yuki Ogasawara, Toshio Miyata, Masanari Itokawa, Genevieve Konopka, Makoto Arai

Redox Biol. 2021 Sep; 45: 102057. Published online 2021 Jun 24. doi: 10.1016/j.redox.2021.102057

PMCID:: PMC8253914

Abstract Article PDF–3.8M

Select item 80682914.

Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits

Shin Koike, Kazuya Toriumi, Sakura Kasahara, Yosuke Kibune, Yo-ichi Ishida, Takashi Dan, Toshio Miyata, Makoto Arai, Yuki Ogasawara

Antioxidants (Basel) 2021 Apr; 10(4): 574. Published online 2021 Apr 8. doi: 10.3390/antiox10040574

PMCID:: PMC8068291

Abstract Article PDF–4.2M

Select item 67251005.

Identification of Glyoxalase-I as a Protein Marker in a Mouse Model of Extremes in Trait Anxiety

Simone A. Krömer, Melanie S. Keßler, Dale Milfay, Isabel N. Birg, Mirjam Bunck, Ludwig Czibere, Markus Panhuysen, Benno Pütz, Jan M. Deussing, Florian Holsboer, Rainer Landgraf, Christoph W. Turck

J Neurosci. 2005 Apr 27; 25(17): 4375–4384. doi: 10.1523/JNEUROSCI.0115-05.2005

PMCID:: PMC6725100

Abstract Article PDF–689K

Select item 59159176.

Glyoxalase (GLO1) inhibition or genetic overexpression does not alter ethanol’s locomotor effects: implications for GLO1 as a therapeutic target in alcohol use disorders

Amanda M Barkley-Levenson, Frances A Lagarda, Abraham A Palmer

Alcohol Clin Exp Res. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Alcohol Clin Exp Res. 2018 May; 42(5): 869–878. Published online 2018 Apr 18. doi: 10.1111/acer.13623

PMCID:: PMC5915917

Abstract Article PDF–1.1M

Select item 54427307.

Glyoxalase‐1 Overexpression Reverses Defective Proangiogenic Function of Diabetic Adipose‐Derived Stem Cells in Streptozotocin‐Induced Diabetic Mice Model of Critical Limb Ischemia

Zhiyou Peng, Xinrui Yang, Jinbao Qin, Kaichuang Ye, Xin Wang, Huihua Shi, Mier Jiang, Xiaobing Liu, Xinwu Lu

Stem Cells Transl Med. 2017 Jan; 6(1): 261–271. Published online 2016 Aug 15. doi: 10.5966/sctm.2015-0380

PMCID:: PMC5442730

Abstract Article PDF–4.9M

Select item 53361588.

Loss of Glyoxalase 1 Induces Compensatory Mechanism to Achieve Dicarbonyl Detoxification in Mammalian Schwann Cells

Jakob Morgenstern, Thomas Fleming, Dagmar Schumacher, Volker Eckstein, Marc Freichel, Stephan Herzig, Peter Nawroth

J Biol Chem. 2017 Feb 24; 292(8): 3224–3238. Published online 2016 Dec 12. doi: 10.1074/jbc.M116.760132

PMCID:: PMC5336158

Abstract Article PDF–2.6M

Select item 49174709.

Genetic and pharmacological manipulation of Glyoxalase 1 regulates voluntary ethanol consumption in mice

Katherine M. J. McMurray, Preetpal S. Sidhu, James M. Cook, Leggy A. Arnold, Abraham A. Palmer

Addict Biol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: Addict Biol. 2017 Mar; 22(2): 381–389. Published online 2015 Dec 22. doi: 10.1111/adb.12333

PMCID:: PMC4917470

Abstract Article PDF–687K

Select item 469302310.

A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

Markus Wortmann, Maani Hakimi, Thomas Fleming, Andreas S. Peters, Tjeerd P. Sijmonsma, Stephan Herzig, Peter P. Nawroth, Dittmar Böckler, Susanne Dihlmann

J Diabetes Res. 2016; 2016: 2981639. Published online 2015 Dec 15. doi: 10.1155/2016/2981639

PMCID:: PMC4693023

Abstract Article PDF–2.4M

Select item 456197511.

Structural basis for 18-β-glycyrrhetinic acid as a novel non-GSH analog glyoxalase I inhibitor

Hong Zhang, Qiang Huang, Jing Zhai, Yi-ning Zhao, Li-ping Zhang, Yun-yun Chen, Ren-wei Zhang, Qing Li, Xiao-peng Hu

Acta Pharmacol Sin. 2015 Sep; 36(9): 1145–1150. Published online 2015 Aug 17. doi: 10.1038/aps.2015.59

PMCID:: PMC4561975

Abstract Article PDF–931K

Select item 386805112.

Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

Ferdinando Giacco, Xueliang Du, Vivette D. D’Agati, Ross Milne, Guangzhi Sui, Michele Geoffrion, Michael Brownlee

Diabetes. 2014 Jan; 63(1): 291–299. Published online 2013 Dec 13. doi: 10.2337/db13-0316

PMCID:: PMC3868051

Abstract Article PDF–1.2M

Select item 376225313.

Characterization of Glyoxalase I in Streptozocin-Induced Diabetic Mouse Models of Painful and Insensate Neuropathy

M.M. Jack, J.M. Ryals, D.E. Wright

Diabetologia. Author manuscript; available in PMC 2013 Sep 4.

Published in final edited form as: Diabetologia. 2011 Aug; 54(8): 2174–2182. Published online 2011 Jun 3. doi: 10.1007/s00125-011-2196-3

PMCID:: PMC3762253

Abstract Article PDF–3.1M

Select item 336640714.

Glyoxalase 1 increases anxiety by reducing GABA_A receptor agonist methylglyoxal

Margaret G. Distler, Leigh D. Plant, Greta Sokoloff, Andrew J. Hawk, Ivy Aneas, Gerald E. Wuenschell, John Termini, Stephen C. Meredith, Marcelo A. Nobrega, Abraham A. Palmer

J Clin Invest. 2012 Jun 1; 122(6): 2306–2315. Published online 2012 May 15. doi: 10.1172/JCI61319

PMCID:: PMC3366407

Abstract Article PDF–965K

Select item 265079215.

A Common and Unstable Copy Number Variant Is Associated with Differences in Glo1 Expression and Anxiety-Like Behavior

Richard Williams, IV, Jackie E. Lim, Bettina Harr, Claudia Wing, Ryan Walters, Margaret G. Distler, Meike Teschke, Chunlei Wu, Tim Wiltshire, Andrew I. Su, Greta Sokoloff, Lisa M. Tarantino, Justin O. Borevitz, Abraham A. Palmer

PLoS One. 2009; 4(3): e4649. Published online 2009 Mar 6. doi: 10.1371/journal.pone.0004649

PMCID:: PMC2650792

Abstract Article PDF–851K

Select item 858030716.

High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice

Shinobu Hirai, Hideki Miwa, Tomoko Tanaka, Kazuya Toriumi, Yasuto Kunii, Hiroko Shimbo, Takuya Sakamoto, Mizuki Hino, Ryuta Izumi, Atsuko Nagaoka, Hirooki Yabe, Tomoya Nakamachi, Seiji Shioda, Takashi Dan, Toshio Miyata, Yasumasa Nishito, Kazuhiro Suzuki, Mitsuhiro Miyashita, Toshifumi Tomoda, Takatoshi Hikida, Junjiro Horiuchi, Masanari Itokawa, Makoto Arai, Haruo Okado

Sci Adv. 2021 Nov; 7(46): eabl6077. Published online 2021 Nov 10. doi: 10.1126/sciadv.abl6077

PMCID:: PMC8580307

Abstract Article PDF–1.4M

Select item 373717017.

Increased Glyoxalase-1 Levels in Fkbp5 Knockout Mice Caused by Glyoxalase-1 Gene Duplication

Lorenz K. Kollmannsberger, Nils C. Gassen, Andrea Bultmann, Jakob Hartmann, Peter Weber, Mathias V. Schmidt, Theo Rein

G3 (Bethesda) 2013 Aug; 3(8): 1311–1313. Published online 2013 Aug 1. doi: 10.1534/g3.113.006445

PMCID:: PMC3737170

Abstract Article PDF–613K

Select item 302982318.

Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress

Alexander Kurz, Naila Rabbani, Michael Walter, Michael Bonin, Paul Thornalley, Georg Auburger, Suzana Gispert

Cell Mol Life Sci. 2011 Feb; 68(4): 721–733. Published online 2010 Aug 14. doi: 10.1007/s00018-010-0483-7

PMCID:: PMC3029823

Abstract Article PDF–329K

Select item 282865619.

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

Markus A. Queisser, Dachun Yao, Sven Geisler, Hans-Peter Hammes, Günter Lochnit, Erwin D. Schleicher, Michael Brownlee, Klaus T. Preissner

Diabetes. 2010 Mar; 59(3): 670–678. Published online 2009 Dec 15. doi: 10.2337/db08-1565

PMCID:: PMC2828656

Abstract Article PDF–418K

Select item 257528220.

The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I

Makoto Kawatani, Hideo Okumura, Kaori Honda, Naoki Kanoh, Makoto Muroi, Naoshi Dohmae, Masamichi Takami, Mitsuhiro Kitagawa, Yushi Futamura, Masaya Imoto, Hiroyuki Osada

Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33): 11691–11696. Published online 2008 Aug 11. doi: 10.1073/pnas.0712239105

PMCID:: PMC2575282

Abstract Article PDF–1.0M

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