PMC Links for Gene (Select 10980) - PMC

Baifu Qin, Shaomin Zou, Kai Li, Huashe Wang, Wenxia Wei, Boyu Zhang, Lishi Xiao, Hyun Ho Choi, Qin Tang, Dandan Huang, Qingxin Liu, Qihao Pan, Manqi Meng, Lekun Fang, Mong-Hong Lee

Br J Cancer. 2020 May 26; 122(11): 1673–1685. Published online 2020 Mar 30. doi: 10.1038/s41416-020-0779-9

Correction in:: Br J Cancer. 2020 Sep 15; 123(6): 1042–1044.

PMCID:: PMC7250844

Abstract Article PDF–3.6M

Select item 46950424.

COP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer

Shujun Gao, Lekun Fang, Liem Minh Phan, Aiham Qdaisat, Sai-Ching J. Yeung, Mong-Hong Lee

Oncotarget. 2015 Sep 29; 6(29): 28026–28041. Published online 2015 Aug 3. doi: 10.18632/oncotarget.4731

PMCID:: PMC4695042

Abstract Article PDF–11M

Select item 35623085.

CDK inhibitor p57^Kip2 is negatively regulated by COP9 signalosome subunit 6

Bo Chen, Ruiying Zhao, Chun-Hui Su, Monica Linan, Chieh Tseng, Liem Phan, Lekuan Fang, Heng-Yin Yang, Huiling Yang, Wenqian Wang, Xiaoyin Xu, Nan Jiang, Shouliang Cai, Feng Jin, Sai-Ching J. Yeung, Mong-Hong Lee

Cell Cycle. 2012 Dec 15; 11(24): 4633–4641. doi: 10.4161/cc.22887

PMCID:: PMC3562308

Abstract Article PDF–1.9M

Select item 78229216.

CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9

Yanli Zhang, Jianbing Hou, Shaomin Shi, Juan Du, Yudong Liu, Pan Huang, Qian Li, Lichao Liu, Huanrong Hu, Yacong Ji, Leiyang Guo, Yaqiong Shi, Yaling Liu, Hongjuan Cui

Cell Death Dis. 2021 Jan; 12(1): 118. Published online 2021 Jan 22. doi: 10.1038/s41419-021-03398-0

PMCID:: PMC7822921

Abstract Article PDF–5.8M

Select item 75788647.

EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis

Hyun Ho Choi, Shaomin Zou, Jian‐lin Wu, Huashe Wang, Liem Phan, Kai Li, Peng Zhang, Daici Chen, Qingxin Liu, Baifu Qin, Thu Anh Thai Nguyen, Sai‐Ching J. Yeung, Lekun Fang, Mong‐Hong Lee

Adv Sci (Weinh) 2020 Oct; 7(20): 2000681. Published online 2020 Sep 23. doi: 10.1002/advs.202000681

PMCID:: PMC7578864

Abstract Article PDF–5.0M

Select item 67436258.

CSN6 promotes tumorigenesis of gastric cancer by ubiquitin-independent proteasomal degradation of p16^INK4a

Wenqi Du, Zongxiang Liu, Wentao Zhu, Tongtong Li, Zhiman Zhu, Lulu Wei, Jun Song, Dongsheng Pei

Cancer Biol Med. 2019 Aug; 16(3): 514–529. doi: 10.20892/j.issn.2095-3941.2018.0410

PMCID:: PMC6743625

Abstract Article PDF–23M

Select item 51019989.

Quercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis

Lin Yang, Yanqing Liu, Mei Wang, Yayun Qian, Xiaoyun Dong, Hao Gu, Haibo Wang, Shiyu Guo, Tadashi Hisamitsu

Mol Med Rep. 2016 Nov; 14(5): 4559–4566. Published online 2016 Oct 10. doi: 10.3892/mmr.2016.5818

PMCID:: PMC5101998

Abstract Article PDF–1.8M

Select item 482562710.

CSN6 positively regulates c-Jun in a MEKK1-dependent manner

Jihyun Shin, Liem Phan, Jian Chen, Zhimin Lu, Mong-Hong Lee

Cell Cycle. 2015; 14(19): 3079–3087. Published online 2015 Aug 3. doi: 10.1080/15384101.2015.1078030

PMCID:: PMC4825627

Abstract Article PDF–717K

Select item 461318111.

Regulating the stability and localization of CDK inhibitor p27^Kip1 via CSN6-COP1 axis

Hyun Ho Choi, Sergei Guma, Lekun Fang, Liem Phan, Cristina Ivan, Keith Baggerly, Anil Sood, Mong-Hong Lee

Cell Cycle. 2015 Jul 18; 14(14): 2265–2273. Published online 2015 May 6. doi: 10.1080/15384101.2015.1046655

PMCID:: PMC4613181

Abstract Article PDF–789K

Select item 1100568912.

CSN6‐SPOP‐HMGCS1 Axis Promotes Hepatocellular Carcinoma Progression via YAP1 Activation

Kai Li, Jiayu Zhang, Haiwen Lyu, Jinneng Yang, Wenxia Wei, Yuzhi Wang, Haidan Luo, Yijing Zhang, Xin Jiang, Hairong Yi, Mengan Wang, Caiyun Zhang, Kang Wu, Lishi Xiao, Weijie Wen, Hui Xu, Guolin Li, Yunle Wan, Fang Yang, Runxiang Yang, Xinhui Fu, Baifu Qin, Zhongguo Zhou, Haipeng Zhang, Mong‐Hong Lee

Adv Sci (Weinh) 2024 Apr; 11(14): 2306827. Published online 2024 Feb 2. doi: 10.1002/advs.202306827

PMCID:: PMC11005689

Abstract Article PDF–9.1M

Select item 878450413.

Helicobacter pylori-induced reactive oxygen species direct turnover of CSN-associated STAMBPL1 and augment apoptotic cell death

Supattra Chaithongyot, Michael Naumann

Cell Mol Life Sci. 2022 Feb; 79(2): 86. Published online 2022 Jan 23. doi: 10.1007/s00018-022-04135-2

PMCID:: PMC8784504

Abstract Article PDF–4.3M

Select item 456009814.

ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer Development

Lekun Fang, Weisi Lu, Hyun Ho Choi, Sai-ching J. Yeung, Jung-Yu Tung, Chwan-Deng Hsiao, Enrique Fuentes-Mattei, David Menter, Lei Wang, Chuangqi Chen, Jianping Wang, Mong-Hong Lee

Cancer Cell. Author manuscript; available in PMC 2016 Aug 10.

Published in final edited form as: Cancer Cell. 2015 Aug 10; 28(2): 183–197. doi: 10.1016/j.ccell.2015.07.004

PMCID:: PMC4560098

Abstract Article PDF–1.6M

Select item 414082115.

Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

Melissa Birol, Radoslav Ivanov Enchev, André Padilla, Florian Stengel, Ruedi Aebersold, Stéphane Betzi, Yinshan Yang, François Hoh, Matthias Peter, Christian Dumas, Aude Echalier

PLoS One. 2014; 9(8): e105688. Published online 2014 Aug 21. doi: 10.1371/journal.pone.0105688

PMCID:: PMC4140821

Abstract Article PDF–2.2M

Select item 351674916.

The Organization of a CSN5-containing Subcomplex of the COP9 Signalosome

Giri Gowda Kotiguda, Dahlia Weinberg, Moshe Dessau, Chiara Salvi, Giovanna Serino, Daniel A. Chamovitz, Joel A. Hirsch

J Biol Chem. 2012 Dec 7; 287(50): 42031–42041. Published online 2012 Oct 18. doi: 10.1074/jbc.M112.387977

PMCID:: PMC3516749

Abstract Article PDF–3.2M

Select item 304940017.

Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers

Ruiying Zhao, Sai-Ching J. Yeung, Jian Chen, Tomoo Iwakuma, Chun-Hui Su, Bo Chen, Changju Qu, Fanmao Zhang, You-Tzung Chen, Yu-Li Lin, Dung-Fang Lee, Feng Jin, Rui Zhu, Tattym Shaikenov, Dos Sarbassov, Aysegul Sahin, Huamin Wang, Hua Wang, Chien-Chen Lai, Fuu-Jen Tsai, Guillermina Lozano, Mong-Hong Lee

J Clin Invest. 2011 Mar 1; 121(3): 851–865. Published online 2011 Feb 7. doi: 10.1172/JCI44111