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Items: 1 to 20 of 43

1.
The prognostic significance and potential mechanism of DBF4 zinc finger in hepatocellular carcinoma
Zhongkai Wu, Lilong Zhang, Xinyi Li, Li Liu, Tianrui Kuang, Zhendong Qiu, Wenhong Deng, Weixing Wang
Sci Rep. 2024; 14: 10662. Published online 2024 May 9. doi: 10.1038/s41598-024-60342-w
PMCID:
PMC11082141
AbstractArticlePDF–15M
2.
DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling
Nanda Kumar Sasi, Flavie Coquel, Yea-Lih Lin, Jeffrey P MacKeigan, Philippe Pasero, Michael Weinreich
Neoplasia. 2018 Oct; 20(10): 985–995. Published online 2018 Aug 26. doi: 10.1016/j.neo.2018.08.001
PMCID:
PMC6111017
AbstractArticlePDF–1004K
3.
DDK Promotes Tumor Chemoresistance and Survival via Multiple Pathways
Nanda Kumar Sasi, Arjun Bhutkar, Nathan J. Lanning, Jeffrey P. MacKeigan, Michael Weinreich
Neoplasia. 2017 May; 19(5): 439–450. Published online 2017 Apr 25. doi: 10.1016/j.neo.2017.03.001
PMCID:
PMC5406526
AbstractArticlePDF–1.3M
4.
Dynamic regulation of histone H3K9 is linked to the switch between replication and transcription at the Dbf4 origin-promoter locus
Kathleen Kylie, Julia Romero, Indeewari K.S. Lindamulage, James Knockleby, Hoyun Lee
Cell Cycle. 2016; 15(17): 2321–2335. Published online 2016 Jun 24. doi: 10.1080/15384101.2016.1201254
PMCID:
PMC5004705
AbstractArticlePDF–1.3M
5.
ATR–Chk1–APC/CCdh1-dependent stabilization of Cdc7–ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
Masayuki Yamada, Kenji Watanabe, Martin Mistrik, Eva Vesela, Iva Protivankova, Niels Mailand, MyungHee Lee, Hisao Masai, Jiri Lukas, Jiri Bartek
Genes Dev. 2013 Nov 15; 27(22): 2459–2472. doi: 10.1101/gad.224568.113
PMCID:
PMC3841735
AbstractArticlePDF–2.4M
6.
Molecular Mechanism of Activation of Human Cdc7 Kinase: BIPARTITE INTERACTION WITH Dbf4/ACTIVATOR OF S PHASE KINASE (ASK) ACTIVATION SUBUNIT STIMULATES ATP BINDING AND SUBSTRATE RECOGNITION
Ryo Kitamura, Rino Fukatsu, Naoko Kakusho, Yong-Soon Cho, Chika Taniyama, Satoshi Yamazaki, Gaik-theng Toh, Kazuo Yanagi, Naoko Arai, Ho-Jin Chang, Hisao Masai
J Biol Chem. 2011 Jul 1; 286(26): 23031–23043. Published online 2011 May 2. doi: 10.1074/jbc.M111.243311
PMCID:
PMC3123071
AbstractArticlePDF–2.1M
7.
Asymmetric bidirectional replication at the human DBF4 origin
Julia Romero, Hoyun Lee
Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Oct 25.
Published in final edited form as: Nat Struct Mol Biol. 2008 Jul; 15(7): 722–729. Published online 2008 Jun 8. doi: 10.1038/nsmb.1439
PMCID:
PMC2963641
AbstractArticlePDF–1.3M
8.
Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection
Nicoletta Bivi, Milena Romanello, Richard Harrison, Ian Clarke, David C Hoyle, Luigi Moro, Fulvia Ortolani, Antonella Bonetti, Franco Quadrifoglio, Gianluca Tell, Daniela Delneri
Genome Biol. 2009; 10(9): R93. Published online 2009 Sep 10. doi: 10.1186/gb-2009-10-9-r93
PMCID:
PMC2768982
AbstractArticlePDF–1.2M
9.
Cdc7-Dbf4 Kinase Overexpression in Multiple Cancers and Tumor Cell Lines Is Correlated with p53 Inactivation
Dorine Bonte, Charlotta Lindvall, Hongyu Liu, Karl Dykema, Kyle Furge, Michael Weinreich
Neoplasia. 2008 Sep; 10(9): 920–931. doi: 10.1593/neo.08216
PMCID:
PMC2517636
AbstractArticlePDF–3.2M
10.
A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells
Hiroyuki Kumagai, Noriko Sato, Masayuki Yamada, Daniel Mahony, Wolfgang Seghezzi, Emma Lees, Ken-Ichi Arai, Hisao Masai
Mol Cell Biol. 1999 Jul; 19(7): 5083–5095. doi: 10.1128/mcb.19.7.5083
PMCID:
PMC84351
AbstractArticlePDF–2.7M
11.
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks
Anja Göder, Chrystelle Antoinat Maric, Michael D. Rainey, Aisling O’Connor, Chiara Cazzaniga, Daniel Shamavu, Jean-Charles Cadoret, Corrado Santocanale
J Cell Biol. 2024 Aug 5; 223(8): e202402144. Published online 2024 Jun 12. doi: 10.1083/jcb.202402144
PMCID:
PMC11169917
AbstractArticlePDF–4.6M
12.
DBF4 Dependent Kinase Inhibition Suppresses Hepatocellular Carcinoma Progression and Potentiates Anti-Programmed Cell Death-1 Therapy
Liang Zhang, Jiawei Hong, Wei Chen, Wei Zhang, Xi Liu, Jiahua Lu, Hong Tang, Zhentao Yang, Ke Zhou, Haiyang Xie, Changku Jia, Donghai Jiang, Shusen Zheng
Int J Biol Sci. 2023; 19(11): 3412–3427. Published online 2023 Jul 3. doi: 10.7150/ijbs.80351
PMCID:
PMC10367558
AbstractArticlePDF–8.4M
13.
Identification and Validation of a Prognostic Model Based on Three MVI-Related Genes in Hepatocellular Carcinoma
Yongchang Tang, Lei Xu, Yupeng Ren, Yuxuan Li, Feng Yuan, Mingbo Cao, Yong Zhang, Meihai Deng, Zhicheng Yao
Int J Biol Sci. 2022; 18(1): 261–275. Published online 2022 Jan 1. doi: 10.7150/ijbs.66536
PMCID:
PMC8692135
AbstractArticlePDF–2.9M
14.
Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer
An Ning Cheng, Chi-Chen Fan, Yu-Kang Lo, Cheng-Liang Kuo, Hui-Chun Wang, I.-Hsin Lien, Shu-Yu Lin, Chung-Hsing Chen, Shih Sheng Jiang, I.-Shou Chang, Hsueh-Fen Juan, Ping-Chiang Lyu, Alan Yueh-Luen Lee
Sci Rep. 2017; 7: 17024. Published online 2017 Dec 5. doi: 10.1038/s41598-017-17126-2
PMCID:
PMC5717001
AbstractArticlePDF–3.9M
15.
DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach
Kevin Z. L. Wu, Guan-Nan Wang, Jennifer Fitzgerald, Huong Quachthithu, Michael D. Rainey, Angela Cattaneo, Angela Bachi, Corrado Santocanale
Nucleic Acids Res. 2016 Oct 14; 44(18): 8786–8798. Published online 2016 Jul 12. doi: 10.1093/nar/gkw626
PMCID:
PMC5062981
AbstractArticlePDF–4.7M
16.
Dbf4 Is Direct Downstream Target of Ataxia Telangiectasia Mutated (ATM) and Ataxia Telangiectasia and Rad3-related (ATR) Protein to Regulate Intra-S-phase Checkpoint
Alan Yueh-Luen Lee, Takuya Chiba, Lan N. Truong, An Ning Cheng, Johnny Do, Michael Jeffrey Cho, Longchuan Chen, Xiaohua Wu
J Biol Chem. 2012 Jan 20; 287(4): 2531–2543. Published online 2011 Nov 28. doi: 10.1074/jbc.M111.291104
PMCID:
PMC3268413
AbstractArticlePDF–2.5M
17.
Transcriptional Co-activator LEDGF Interacts with Cdc7-Activator of S-phase Kinase (ASK) and Stimulates Its Enzymatic Activity
Siobhan Hughes, Victoria Jenkins, Mohd Jamal Dar, Alan Engelman, Peter Cherepanov
J Biol Chem. 2010 Jan 1; 285(1): 541–554. Published online 2009 Oct 28. doi: 10.1074/jbc.M109.036491
PMCID:
PMC2804203
AbstractArticlePDF–4.6M
18.
Cdc7/Dbf4 and the Human S Checkpoint Response to UVC
Timothy P. Heffernan, Keziban Ünsal-Kaçmaz, Alexandra N. Heinloth, Dennis A. Simpson, Richard S. Paules, Aziz Sancar, Marila Cordeiro-Stone, William K. Kaufmann
J Biol Chem. Author manuscript; available in PMC 2007 Mar 30.
Published in final edited form as: J Biol Chem. 2007 Mar 30; 282(13): 9458–9468. Published online 2007 Feb 2. doi: 10.1074/jbc.M611292200
PMCID:
PMC1839878
AbstractArticlePDF–804K
19.
The role of Dbf4/Drf1-dependent kinase Cdc7 (Ddk) in DNA damage checkpoint control
Toshiya Tsuji, Eric Lau, Gary G. Chiang, Wei Jiang
Mol Cell. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Mol Cell. 2008 Dec 26; 32(6): 862–869. doi: 10.1016/j.molcel.2008.12.005
PMCID:
PMC4556649
AbstractArticlePDF–693K
20.
Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation
Subhalakshmi Sharma, Kateřina Čermáková, Jan De Rijck, Jonas Demeulemeester, Milan Fábry, Sara El Ashkar, Siska Van Belle, Martin Lepšík, Petr Tesina, Vojtěch Duchoslav, Petr Novák, Martin Hubálek, Pavel Srb, Frauke Christ, Pavlína Řezáčová, H. Courtney Hodges, Zeger Debyser, Václav Veverka
Proc Natl Acad Sci U S A. 2018 Jul 24; 115(30): E7053–E7062. Published online 2018 Jul 11. doi: 10.1073/pnas.1803909115
PMCID:
PMC6065015
AbstractArticlePDF–1.8M

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