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Select item 104944001.

Cortex-restricted deletion of Foxp1 impairs barrel formation and induces aberrant tactile responses in a mouse model of autism

Xue Li, Shishuai Hao, Shimin Zou, Xiaomeng Tu, Weixi Kong, Tian Jiang, Jie-Guang Chen

Mol Autism. 2023; 14: 34. Published online 2023 Sep 11. doi: 10.1186/s13229-023-00567-0

PMCID:: PMC10494400

Abstract Article PDF–12M

Select item 102394712.

A single-cell trajectory atlas of striatal development

Ashley G. Anderson, Ashwinikumar Kulkarni, Genevieve Konopka

Sci Rep. 2023; 13: 9031. Published online 2023 Jun 3. doi: 10.1038/s41598-023-36255-5

PMCID:: PMC10239471

Abstract Article PDF–4.7M

Select item 93754933.

Endothelial Foxp1 Regulates Neointimal Hyperplasia Via Matrix Metalloproteinase‐9/Cyclin Dependent Kinase Inhibitor 1B Signal Pathway

Xiaoli Chen, Jianfei Xu, Wenzhen Bao, Hongda Li, Wenrun Wu, Jiwen Liu, Jingjiang Pi, Brian Tomlinson, Paul Chan, Chengchao Ruan, Qi Zhang, Lin Zhang, Huimin Fan, Edward Morrisey, Zhongmin Liu, Yuzhen Zhang, Li Lin, Jie Liu, Tao Zhuang

J Am Heart Assoc. 2022 Aug 2; 11(15): e026378. Published online 2022 Jul 29. doi: 10.1161/JAHA.122.026378

Correction in:: J Am Heart Assoc. 2023 Feb 21; 12(4): e020899.

PMCID:: PMC9375493

Abstract Article PDF–3.8M

Select item 88727294.

Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome

Jing Wang, Henning Fröhlich, Felipe Bodaleo Torres, Rangel Leal Silva, Gernot Poschet, Amit Agarwal, Gudrun A. Rappold

Proc Natl Acad Sci U S A. 2022 Feb 22; 119(8): e2112852119. Published online 2022 Feb 14. doi: 10.1073/pnas.2112852119

PMCID:: PMC8872729

Abstract Article PDF–2.2M

Select item 87753225.

Disrupted Mitochondrial Network Drives Deficits of Learning and Memory in a Mouse Model of FOXP1 Haploinsufficiency

Jing Wang, Gudrun A. Rappold, Henning Fröhlich

Genes (Basel) 2022 Jan; 13(1): 127. Published online 2022 Jan 11. doi: 10.3390/genes13010127

PMCID:: PMC8775322

Abstract Article PDF–1.6M

Select item 82553286.

FOXP1 negatively regulates intrinsic excitability in D2 striatal projection neurons by promoting inwardly rectifying and leak potassium currents

Nitin Khandelwal, Sheridan Cavalier, Volodymyr Rybalchenko, Ashwinikumar Kulkarni, Ashley G. Anderson, Genevieve Konopka, Jay R. Gibson

Mol Psychiatry. 2021; 26(6): 1761–1774. Published online 2021 Jan 5. doi: 10.1038/s41380-020-00995-x

PMCID:: PMC8255328

Abstract Article PDF–3.1M

Select item 77786017.

Endothelial Klf2-Foxp1-TGFβ signal mediates the inhibitory effects of simvastatin on maladaptive cardiac remodeling

Hongda Li, Yanfang Wang, Jiwen Liu, Xiaoli Chen, Yunhao Duan, Xiaoyu Wang, Yajing Shen, Yashu Kuang, Tao Zhuang, Brain Tomlinson, Paul Chan, Zuoren Yu, Yu Cheng, Lin Zhang, Zhongmin Liu, Yuzhen Zhang, Zhenlin Zhao, Qi Zhang, Jie Liu

Theranostics. 2021; 11(4): 1609–1625. Published online 2021 Jan 1. doi: 10.7150/thno.48153

PMCID:: PMC7778601

Abstract Article PDF–3.7M

Select item 68252838.

Gastrointestinal dysfunction in autism displayed by altered motility and achalasia in Foxp1^+/− mice

Henning Fröhlich, Marie Luise Kollmeyer, Valerie Catherine Linz, Manuel Stuhlinger, Dieter Groneberg, Amelie Reigl, Eugen Zizer, Andreas Friebe, Beate Niesler, Gudrun Rappold

Proc Natl Acad Sci U S A. 2019 Oct 29; 116(44): 22237–22245. Published online 2019 Oct 14. doi: 10.1073/pnas.1911429116

PMCID:: PMC6825283

Abstract Article PDF–1.5M

Select item 48686299.

Foxp1 controls naive CD8⁺ T cell quiescence by simultaneously repressing key pathways in cellular metabolism and cell cycle progression

Hairong Wei, Jianlin Geng, Bi Shi, Zhenghui Liu, Yin-Hu Wang, Anna C. Stevens, Stephanie L Sprout, Min Yao, Haikun Wang, Hui Hu

J Immunol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: J Immunol. 2016 May 1; 196(9): 3537–3541. Published online 2016 Mar 21. doi: 10.4049/jimmunol.1501896

PMCID:: PMC4868629

Abstract Article PDF–333K

Select item 468328010.

Forkhead Box P1 (FOXP1) Transcription Factor Regulates Hepatic Glucose Homeostasis

Yongkang Zou, Ning Gong, Ying Cui, Xiaojuan Wang, Anfang Cui, Qi Chen, Tao Jiao, Xueyu Dong, Hao Yang, Shutian Zhang, Fude Fang, Yongsheng Chang

J Biol Chem. 2015 Dec 18; 290(51): 30607–30615. Published online 2015 Oct 26. doi: 10.1074/jbc.M115.681627

PMCID:: PMC4683280

Abstract Article PDF–1.3M

Select item 450174811.

Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling

Jianzhi Zhao, Hanjun Li, Rujiang Zhou, Gang Ma, Joseph D. Dekker, Haley O. Tucker, Zhengju Yao, Xizhi Guo

PLoS One. 2015; 10(7): e0131674. Published online 2015 Jul 14. doi: 10.1371/journal.pone.0131674

PMCID:: PMC4501748

Abstract Article PDF–2.7M

Select item 281098412.

Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development

Xiaoming Feng, Gregory C. Ippolito, Lifeng Tian, Karla Wiehagen, Soyoung Oh, Arivazhagan Sambandam, Jessica Willen, Ralph M. Bunte, Shanna D. Maika, June V. Harriss, Andrew J. Caton, Avinash Bhandoola, Philip W. Tucker, Hui Hu

Blood. 2010 Jan 21; 115(3): 510–518. Prepublished online 2009 Nov 12. doi: 10.1182/blood-2009-07-232694

PMCID:: PMC2810984

Abstract Article

Select item 1123488713.

Compensation between FOXP transcription factors maintains proper striatal function

Newaz I. Ahmed, Nitin Khandelwal, Ashley G. Anderson, Emily Oh, Rachael M. Vollmer, Ashwinikumar Kulkarni, Jay R. Gibson, Genevieve Konopka

Cell Rep. Author manuscript; available in PMC 2024 Jul 10.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114257. Published online 2024 May 17. doi: 10.1016/j.celrep.2024.114257

PMCID:: PMC11234887

Abstract Article PDF–2.9M

Select item 1103139614.

Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1

Meng Wu, Weicheng Tang, Ying Chen, Liru Xue, Jun Dai, Yan Li, Xiaoran Zhu, Chuqing Wu, Jiaqiang Xiong, Jinjin Zhang, Tong Wu, Su Zhou, Dan Chen, Chaoyang Sun, Jing Yu, Hongyi Li, Yican Guo, Yibao Huang, Qingqing Zhu, Simin Wei, Ziliang Zhou, Mingfu Wu, Ya Li, Tao Xiang, Huiying Qiao, Shixuan Wang

Nat Aging. 2024; 4(4): 527–545. Published online 2024 Apr 9. doi: 10.1038/s43587-024-00607-1

PMCID:: PMC11031396

Abstract Article PDF–30M

Select item 897419515.

Forkhead box protein 1 transcriptionally activates sestrin1 to alleviate oxidized low-density lipoprotein-induced inflammation and lipid accumulation in macrophages

Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou

Bioengineered. 2022; 13(2): 2917–2926. Published online 2022 Jan 19. doi: 10.1080/21655979.2021.2000228

PMCID:: PMC8974195

Abstract Article PDF–2.9M

Select item 753489916.

Transcription factor Foxp1 regulates Foxp3 chromatin binding and maintains regulatory T cell function

Catherine Konopacki, Yuri Pritykin, Yury Rubtsov, Christina S. Leslie, Alexander Y. Rudensky

Nat Immunol. Author manuscript; available in PMC 2020 Oct 5.

Published in final edited form as: Nat Immunol. 2019 Feb; 20(2): 232–242. Published online 2019 Jan 14. doi: 10.1038/s41590-018-0291-z

PMCID:: PMC7534899

Abstract Article PDF–2.9M

Select item 750207217.

A novel epigenetic regulation of circFoxp1 on Foxp1 in colon cancer cells

Yanwei Luo, Fengxia Liu, Jinqi Ma, Yunfeng Fu, Rong Gui

Cell Death Dis. 2020 Sep; 11(9): 782. Published online 2020 Sep 19. doi: 10.1038/s41419-020-03007-6

PMCID:: PMC7502072

Abstract Article PDF–1.3M

Select item 713793018.

Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development

Ashley G. Anderson, Ashwinikumar Kulkarni, Matthew Harper, Genevieve Konopka

Cell Rep. Author manuscript; available in PMC 2020 Apr 7.

Published in final edited form as: Cell Rep. 2020 Mar 3; 30(9): 3051–3066.e7. doi: 10.1016/j.celrep.2020.02.030

PMCID:: PMC7137930

Abstract Article PDF–4.1M

Select item 683831219.

Foxp1 controls brown/beige adipocyte differentiation and thermogenesis through regulating β3-AR desensitization

Pei Liu, Sixia Huang, Shifeng Ling, Shuqin Xu, Fuhua Wang, Wei Zhang, Rujiang Zhou, Lin He, Xuechun Xia, Zhengju Yao, Ying Fan, Niansong Wang, Congxia Hu, Xiaodong Zhao, Haley O. Tucker, Jiqiu Wang, Xizhi Guo

Nat Commun. 2019; 10: 5070. Published online 2019 Nov 7. doi: 10.1038/s41467-019-12988-8

PMCID:: PMC6838312

Abstract Article PDF–2.8M

Select item 612677320.

Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion

Shuqin Xu, Pei Liu, Yuanxing Chen, Yi Chen, Wei Zhang, Haixia Zhao, Yiwei Cao, Fuhua Wang, Nana Jiang, Shifeng Lin, Baojie Li, Zhenlin Zhang, Zhanying Wei, Ying Fan, Yunyun Jin, Lin He, Rujiang Zhou, Joseph D. Dekker, Haley O. Tucker, Simon E. Fisher, Zhengju Yao, Quansheng Liu, Xuechun Xia, Xizhi Guo

Proc Natl Acad Sci U S A. 2018 Aug 28; 115(35): 8799–8804. Published online 2018 Aug 13. doi: 10.1073/pnas.1721820115