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Items: 1 to 20 of 31

1.
Systemic depletion of WWP1 improves insulin sensitivity and lowers triglyceride content in the liver of obese mice
Yuka Nozaki, Masaki Kobayashi, Hiroki Wakasawa, Shunsuke Hoshino, Fumika Suwa, Yuko Ose, Ryoma Tagawa, Yoshikazu Higami
FEBS Open Bio. 2023 Jun; 13(6): 1086–1094. Published online 2023 Apr 20. doi: 10.1002/2211-5463.13610
PMCID:
PMC10240335
AbstractArticlePDF–1.8M
2.
WWP1 Deficiency Alleviates Cardiac Remodeling Induced by Simulated Microgravity
Guohui Zhong, Dingsheng Zhao, Jianwei Li, Zifan Liu, Junjie Pan, Xinxin Yuan, Wenjuan Xing, Yinglong Zhao, Shukuan Ling, Yingxian Li
Front Cell Dev Biol. 2021; 9: 739944. Published online 2021 Oct 18. doi: 10.3389/fcell.2021.739944
PMCID:
PMC8558417
AbstractArticlePDF–11M
3.
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
Yu-Ru Lee, Ming Chen, Jonathan D. Lee, Jinfang Zhang, Shu-Yu Lin, Tian-Min Fu, Hao Chen, Tomoki Ishikawa, Shang-Yin Chiang, Jesse Katon, Yang Zhang, Yulia V. Shulga, Assaf C. Bester, Jacqueline Fung, Emanuele Monteleone, Lixin Wan, Chen Shen, Chih-Hung Hsu, Antonella Papa, John G. Clohessy, Julie Teruya-Feldstein, Suresh Jain, Hao Wu, Lydia Matesic, Ruey-Hwa Chen, Wenyi Wei, Pier Paolo Pandolfi
Science. Author manuscript; available in PMC 2020 Mar 19.
Published in final edited form as: Science. 2019 May 17; 364(6441): eaau0159. doi: 10.1126/science.aau0159
PMCID:
PMC7081834
AbstractArticlePDF–2.2M
4.
Ubiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration
Lei Shu, Hengwei Zhang, Brendan Boyce, Lianping Xing
J Bone Miner Res. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: J Bone Miner Res. 2013 Sep; 28(9): 1925–1935. doi: 10.1002/jbmr.1938
PMCID:
PMC3749248
AbstractArticlePDF–3.8M
5.
WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models
Takahiro Kishikawa, Hiroshi Higuchi, Limei Wang, Nivedita Panch, Valerie Maymi, Sachem Best, Samuel Lee, Genso Notoya, Alex Toker, Lydia E. Matesic, Gerburg M. Wulf, Wenyi Wei, Motoyuki Otsuka, Kazuhiko Koike, John G. Clohessy, Yu-Ru Lee, Pier Paolo Pandolfi
J Clin Invest. 2021 Dec 15; 131(24): e140436. Published online 2021 Dec 15. doi: 10.1172/JCI140436
PMCID:
PMC8670846
AbstractArticlePDF–3.0M
6.
The ubiquitin ligase WWP1 contributes to shifts in matrix proteolytic profiles and a myocardial aging phenotype with diastolic heart
Lydia E. Matesic, Lisa A. Freeburg, Laura B. Snyder, Lauren-Ashley Duncan, Amber Moore, Paige E. Perreault, Kia N. Zellars, Edie C. Goldsmith, Francis G. Spinale
Am J Physiol Heart Circ Physiol. 2020 Oct 1; 319(4): H765–H774. Published online 2020 Aug 21. doi: 10.1152/ajpheart.00620.2019
PMCID:
PMC7717125
AbstractArticle
7.
WWP1 knockout in mice exacerbates obesity‐related phenotypes in white adipose tissue but improves whole‐body glucose metabolism
Shunsuke Hoshino, Masaki Kobayashi, Ryoma Tagawa, Ryutaro Konno, Takuro Abe, Kazuhiro Furuya, Kumi Miura, Hiroki Wakasawa, Naoyuki Okita, Yuka Sudo, Yuhei Mizunoe, Yoshimi Nakagawa, Takeshi Nakamura, Hiroshi Kawabe, Yoshikazu Higami
FEBS Open Bio. 2020 Mar; 10(3): 306–315. Published online 2020 Feb 3. doi: 10.1002/2211-5463.12795
PMCID:
PMC7050250
AbstractArticlePDF–1.2M
8.
Tumor Necrosis Factor Inhibits Mesenchymal Stem Cell Differentiation into Osteoblasts Via the Ubiquitin E3 Ligase Wwp1
Lan Zhao, Jian Huang, Hengwei Zhang, Yi Wang, Lydia E. Matesic, Masahiko Takahata, Hani Awad, Di Chen, Lianping Xing
Stem Cells. Author manuscript; available in PMC 2013 Jul 11.
Published in final edited form as: Stem Cells. 2011 Oct; 29(10): 1601–1610. doi: 10.1002/stem.703
PMCID:
PMC3708970
AbstractArticlePDF–2.4M
9.
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened
Bo Lv, Michael W. Stuck, Paurav B. Desai, Oscar A. Cabrera, Gregory J. Pazour
J Cell Biol. 2021 Sep 6; 220(9): e202010177. Published online 2021 Jun 23. doi: 10.1083/jcb.202010177
PMCID:
PMC8236919
AbstractArticlePDF–7.4M
10.
Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis
Yu Hirata, Kazuhiro Nomura, Yoko Senga, Yuko Okada, Kenta Kobayashi, Shiki Okamoto, Yasuhiko Minokoshi, Michihiro Imamura, Shin’ichi Takeda, Tetsuya Hosooka, Wataru Ogawa
JCI Insight. 2019 Feb 21; 4(4): e124952. Published online 2019 Feb 21. doi: 10.1172/jci.insight.124952
PMCID:
PMC6478420
AbstractArticlePDF–14M
11.
Cardiomyocyte-Specific Overexpression of the Ubiquitin Ligase Wwp1 Contributes to Reduction in Connexin 43 and Arrhythmogenesis
Wassim A. Basheer, Brett S. Harris, Heather L. Mentrup, Measho Abreha, Elizabeth L. Thames, Jessica B. Lea, Deborah A. Swing, Neal G. Copeland, Nancy A. Jenkins, Robert L. Price, Lydia E. Matesic
J Mol Cell Cardiol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Nov; 88: 1–13. Published online 2015 Sep 16. doi: 10.1016/j.yjmcc.2015.09.004
PMCID:
PMC4641030
AbstractArticlePDF–2.4M
12.
E3 Ubiquitin Ligase, WWP1, Interacts with AMPKα2 and Down-regulates Its Expression in Skeletal Muscle C2C12 Cells
Jung Ok Lee, Soo Kyung Lee, Nami Kim, Ji Hae Kim, Ga Young You, Ji Wook Moon, Sha Jie, Su Jin Kim, Yong Woo Lee, Ho Jin Kang, Yongchul Lim, Sun Hwa Park, Hyeon Soo Kim
J Biol Chem. 2013 Feb 15; 288(7): 4673–4680. Published online 2013 Jan 4. doi: 10.1074/jbc.M112.406009
PMCID:
PMC3576072
AbstractArticlePDF–1.3M
13.
WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1) Negatively Regulates TLR4-Mediated TNF-α and IL-6 Production by Proteasomal Degradation of TNF Receptor Associated Factor 6 (TRAF6)
Xiao-Wen Lin, Wei-Cheng Xu, Jian-Gang Luo, Xue-Jiao Guo, Tao Sun, Xu-Li Zhao, Zhi-Jian Fu
PLoS One. 2013; 8(6): e67633. Published online 2013 Jun 17. doi: 10.1371/journal.pone.0067633
PMCID:
PMC3684580
AbstractArticlePDF–1.0M
14.
The E3 Ubiquitin Ligase WWP1 Selectively Targets HER4 and Its Proteolytically Derived Signaling Isoforms for Degradation
Shu-Mang Feng, Rebecca S. Muraoka-Cook, Debra Hunter, Melissa A. Sandahl, Laura S. Caskey, Keiji Miyazawa, Azeddine Atfi, H. Shelton Earp, III
Mol Cell Biol. 2009 Feb; 29(3): 892–906. Published online 2008 Dec 1. doi: 10.1128/MCB.00595-08
PMCID:
PMC2630679
AbstractArticlePDF–4.9M
15.
Transmembrane adaptor protein WBP1L regulates CXCR4 signalling and murine haematopoiesis
Simon Borna, Ales Drobek, Jarmila Kralova, Daniela Glatzova, Iva Splichalova, Matej Fabisik, Jana Pokorna, Tereza Skopcova, Pavla Angelisova, Veronika Kanderova, Julia Starkova, Petr Stanek, Orest V. Matveichuk, Nataliia Pavliuchenko, Katarzyna Kwiatkowska, Majd B. Protty, Michael G. Tomlinson, Meritxell Alberich‐Jorda, Vladimir Korinek, Tomas Brdicka
J Cell Mol Med. 2020 Jan; 24(2): 1980–1992. Published online 2019 Dec 17. doi: 10.1111/jcmm.14895
PMCID:
PMC6991692
AbstractArticlePDF–1.8M
16.
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalenceof Germline Recombination and Influencing Factors
Lin Luo, Mateusz C. Ambrozkiewicz, Fritz Benseler, Cui Chen, Emilie Dumontier, Susanne Falkner, Elisabetta Furlanis, Andrea M. Gomez, Naosuke Hoshina, Wei-Hsiang Huang, Mary Anne Hutchison, Yu Itoh-Maruoka, Laura A. Lavery, Wei Li, Tomohiko Maruo, Junko Motohashi, Emily Ling-Lin Pai, Kenneth A. Pelkey, Ariane Pereira, Thomas Philips, Jennifer L. Sinclair, Jeff A. Stogsdill, Lisa Traunmüller, Jiexin Wang, Joke Wortel, Wenjia You, Nashat Abumaria, Kevin T. Beier, Nils Brose, Harold A. Burgess, Constance L. Cepko, Jean-François Cloutier, Cagla Eroglu, Sandra Goebbels, Pascal S. Kaeser, Jeremy N. Kay, Wei Lu, Liqun Luo, Kenji Mandai, Chris J. McBain, Klaus-Armin Nave, Marco A.M. Prado, Vania F. Prado, Jeffrey Rothstein, John L.R. Rubenstein, Gesine Saher, Kenji Sakimura, Joshua R. Sanes, Peter Scheiffele, Yoshimi Takai, Hisashi Umemori, Matthijs Verhage, Michisuke Yuzaki, Huda Yahya Zoghbi, Hiroshi Kawabe, Ann Marie Craig
Neuron. Author manuscript; available in PMC 2021 Apr 8.
Published in final edited form as: Neuron. 2020 Apr 8; 106(1): 37–65.e5. Published online 2020 Feb 5. doi: 10.1016/j.neuron.2020.01.008
PMCID:
PMC7377387
AbstractArticlePDF–2.3M
17.
An atlas of combinatorial transcriptional regulation in mouse and man
The FANTOM consortium and RIKEN Omics Science Center
Cell. Author manuscript; available in PMC 2011 Mar 5.
Published in final edited form as: Cell. 2010 Mar 5; 140(5): 744–752. doi: 10.1016/j.cell.2010.01.044
Correction in:
volume 141 on page 369
PMCID:
PMC2836267
AbstractArticlePDF–2.2M
18.
Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method
Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko
Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501
PMCID:
PMC311119
AbstractArticlePDF–743K
19.
A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58
Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara
Dev Cell. Author manuscript; available in PMC 2011 Jun 7.
Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011
PMCID:
PMC3110151
AbstractArticlePDF–2.0M
20.
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin
Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064
PMCID:
PMC165511
AbstractArticlePDF–217K

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