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Select item 99955861.

Genetic variants and haplotypes in fibulin-5 (FBLN5) are associated with pseudoexfoliation glaucoma but not with pseudoexfoliation syndrome

Ramani Shyam Kapuganti, Barsha Bharati, Pranjya Paramita Mohanty, Debasmita Pankaj Alone

Biosci Rep. 2023 Mar 31; 43(3): BSR20221622. Published online 2023 Mar 2. doi: 10.1042/BSR20221622

PMCID:: PMC9995586

Abstract Article PDF–1.0M

Select item 68711342.

De novo variants in an extracellular matrix protein coding gene, fibulin-5 (FBLN5) are associated with pseudoexfoliation

Biswajit Padhy, Ramani Shyam Kapuganti, Bushra Hayat, Pranjya Paramita Mohanty, Debasmita Pankaj Alone

Eur J Hum Genet. 2019 Dec; 27(12): 1858–1866. Published online 2019 Jul 29. doi: 10.1038/s41431-019-0482-6

PMCID:: PMC6871134

Abstract Article PDF–706K

Select item 55412643.

Adult-onset demyelinating neuropathy associated with FBLN5 gene mutation

Si Cheng, He Lv, Wei Zhang, Zhaoxia Wang, Xin Shi, Wei Liang, Yun Yuan

Clin Neuropathol. 2017 Jul-Aug; 36(4): 171–177. Published online 2017 Mar 23. doi: 10.5414/NP301011

PMCID:: PMC5541264

Abstract Article PDF–1.5M

Select item 46079104.

Effect of fibulin-5 on adhesion, migration and invasion of hepatocellular carcinoma cells via an integrin-dependent mechanism

Jia-Cheng Tang, Jing-Hua Liu, Xiao-Long Liu, Xiao Liang, Xiu-Jun Cai

World J Gastroenterol. 2015 Oct 21; 21(39): 11127–11140. Published online 2015 Oct 21. doi: 10.3748/wjg.v21.i39.11127

PMCID:: PMC4607910

Abstract Article PDF–2.0M

Select item 42954775.

Fibulin-5 inhibits hepatocellular carcinoma cell migration and invasion by down-regulating matrix metalloproteinase-7 expression

Kangsheng Tu, Changwei Dou, Xin Zheng, Chao Li, Wei Yang, Yingmin Yao, Qingguang Liu

BMC Cancer. 2014; 14: 938. Published online 2014 Dec 12. doi: 10.1186/1471-2407-14-938

PMCID:: PMC4295477

Abstract Article PDF–1.8M

Select item 32723866.

Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin

Michaela Auer-Grumbach, Martin Weger, Regina Fink-Puches, Lea Papić, Eleonore Fröhlich, Piet Auer-Grumbach, Laila El Shabrawi-Caelen, Maria Schabhüttl, Christian Windpassinger, Jan Senderek, Herbert Budka, Slave Trajanoski, Andreas R. Janecke, Anton Haas, Dieter Metze, Thomas R. Pieber, Christian Guelly

Brain. Author manuscript; available in PMC 2012 Feb 5.

Published in final edited form as: Brain. 2011 Jun; 134(Pt 6): 1839–1852. Published online 2011 May 15. doi: 10.1093/brain/awr076

PMCID:: PMC3272386

Abstract Article PDF–2.6M

Select item 20640897.

Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo

Maretoshi Hirai, Tetsuya Ohbayashi, Masahito Horiguchi, Katsuya Okawa, Akari Hagiwara, Kenneth R. Chien, Toru Kita, Tomoyuki Nakamura

J Cell Biol. 2007 Mar 26; 176(7): 1061–1071. doi: 10.1083/jcb.200611026

PMCID:: PMC2064089

Abstract Article PDF–6.0M

Select item 107889218.

FBLN5 was Regulated by PRDM9, and Promoted Senescence and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells

Mengyao Zhao, Rong Rong, Chen Zhang, Haoqing Yang, Xiao Han, Zhipeng Fan, Ying Zheng, Jianpeng Zhang

Curr Stem Cell Res Ther. 2023 Nov 29; 19(3): 417–425. Published online 2023 Nov 29. doi: 10.2174/1574888X18666230822100054

PMCID:: PMC10788921

Abstract Article PDF–4.9M

Select item 105880489.

Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC

Motasim Masood, Qize Ding, Adam D. Cawte, David S. Rueda, Stefan W. Grimm, Ernesto Yagüe, Mona El-Bahrawy

Cell Commun Signal. 2023; 21: 295. Published online 2023 Oct 20. doi: 10.1186/s12964-023-01300-3

PMCID:: PMC10588048

Abstract Article PDF–9.4M

Select item 927588910.

Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5)

Yi Li, Xiaojuan Yang, Dan Lu

Bioengineered. 2022; 13(5): 11867–11880. Published online 2022 May 11. doi: 10.1080/21655979.2022.2060162

PMCID:: PMC9275889

Abstract Article PDF–6.1M

Select item 755098311.

FBLN5 is targeted by microRNA-27a-3p and suppresses tumorigenesis and progression in high-grade serous ovarian carcinoma

Rongrong Li, Huan Wu, Huiyang Jiang, Qiuman Wang, Zhiyuan Dou, Hanlin Ma, Shi Yan, Cunzhong Yuan, Ning Yang, Beihua Kong

Oncol Rep. 2020 Nov; 44(5): 2143–2151. Published online 2020 Sep 3. doi: 10.3892/or.2020.7749

PMCID:: PMC7550983

Abstract Article PDF–2.3M

Select item 622320412.

IDH1 mutation promotes lung cancer cell proliferation through methylation of Fibulin-5

Bingdi Yan, Yanbing Hu, Tiangang Ma, Yanjun Wang

Open Biol. 2018 Oct; 8(10): 180086. Published online 2018 Oct 10. doi: 10.1098/rsob.180086

PMCID:: PMC6223204

Abstract Article PDF–1.0M

Select item 304496613.

Fibulin-5 Is Up-regulated by Hypoxia in Endothelial Cells through a Hypoxia-inducible Factor-1 (HIF-1α)-dependent Mechanism

Anna Guadall, Mar Orriols, Ricardo Rodríguez-Calvo, Olivier Calvayrac, Javier Crespo, Rosa Aledo, José Martínez-González, Cristina Rodríguez

J Biol Chem. 2011 Mar 4; 286(9): 7093–7103. Published online 2010 Dec 30. doi: 10.1074/jbc.M110.162917

PMCID:: PMC3044966

Abstract Article PDF–2.2M

Select item 286847814.

Structural Effects of Fibulin 5 Missense Mutations Associated with Age-Related Macular Degeneration and Cutis Laxa

Richard P. O. Jones, Caroline Ridley, Thomas A. Jowitt, Ming-Chuan Wang, Marjorie Howard, Nicoletta Bobola, Tao Wang, Paul N. Bishop, Cay M. Kielty, Clair Baldock, Andrew J. Lotery, Dorothy Trump

Invest Ophthalmol Vis Sci. 2010 May; 51(5): 2356–2362. doi: 10.1167/iovs.09-4620

PMCID:: PMC2868478

Abstract Article PDF–346K

Select item 275799415.

Fibulin 5 Forms a Compact Dimer in Physiological Solutions

Richard P. O. Jones, Ming-Chuan Wang, Thomas A. Jowitt, Caroline Ridley, Kieran T. Mellody, Marjorie Howard, Tao Wang, Paul N. Bishop, Andrew J. Lotery, Cay M. Kielty, Clair Baldock, Dorothy Trump

J Biol Chem. 2009 Sep 18; 284(38): 25938–25943. Published online 2009 Jul 17. doi: 10.1074/jbc.M109.011627

PMCID:: PMC2757994

Abstract Article PDF–708K

Select item 490930116.

Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells

Wilson Chan, Hodan Ismail, Dominique Mayaki, Veronica Sanchez, Kerstin Tiedemann, Elaine C. Davis, Sabah N. A. Hussain

PLoS One. 2016; 11(6): e0156994. Published online 2016 Jun 15. doi: 10.1371/journal.pone.0156994

PMCID:: PMC4909301

Abstract Article PDF–1.3M

Select item 455813317.

Fibulin-5 inhibits Wnt/β-catenin signaling in lung cancer

Xiaojun Chen, Xiaomeng Song, Wen Yue, Dongshi Chen, Jian Yu, Zhi Yao, Lin Zhang

Oncotarget. 2015 Jun 20; 6(17): 15022–15034. Published online 2015 Apr 2. doi: 10.18632/oncotarget.3609

PMCID:: PMC4558133

Abstract Article PDF–8.0M

Select item 410585018.

COMPREHENSIVE CLINICAL AND MOLECULAR ANALYSIS OF 12 FAMILIES WITH TYPE 1 RECESSIVE CUTIS LAXA

Bert Callewaert, Chi-Ting Su, Tim Van Damme, Philip Vlummens, Fransiska Malfait, Olivier Vanakker, Bianca Schulz, Meghan Mac Neal, Elaine C. Davis, Joseph G.H. Lee, Aicha Salhi, Sheila Unger, Ketil Heimdal, Salome De Almeida, Uwe Kornak, Harald Gaspar, Jean-Luc Bresson, Katrina Prescott, Maria E. Gosendi, Sahar Mansour, Gérald E. Piérard, Suneeta Madan-Khetarpal, Frank C. Sciurba, Sofie Symoens, Paul J Coucke, Lionel Van Maldergem, Zsolt Urban, Anne De Paepe

Hum Mutat. Author manuscript; available in PMC 2014 Jul 22.

Published in final edited form as: Hum Mutat. 2013 Jan; 34(1): 111–121. Published online 2012 Aug 13. doi: 10.1002/humu.22165

PMCID:: PMC4105850

Abstract Article PDF–4.1M

Select item 382936619.

Fibulin-3, -4, and -5 Are Highly Susceptible to Proteolysis, Interact with Cells and Heparin, and Form Multimers

Jelena Djokic, Christine Fagotto-Kaufmann, Rainer Bartels, Valentin Nelea, Dieter P. Reinhardt

J Biol Chem. 2013 Aug 2; 288(31): 22821–22835. Published online 2013 Jun 19. doi: 10.1074/jbc.M112.439158

PMCID:: PMC3829366

Abstract Article PDF–3.7M

Select item 226729720.

Fibulin-5 binds human smooth-muscle cells through α5β1 and α4β1 integrins, but does not support receptor activation

Amanda C. Lomas, Kieran T. Mellody, Lyle J. Freeman, Daniel V. Bax, C. Adrian Shuttleworth, Cay M. Kielty

Biochem J. 2007 Aug 1; 405(Pt 3): 417–428. Prepublished online 2007 May 2. Published online 2007 Jul 13. doi: 10.1042/BJ20070400

PMCID:: PMC2267297

Abstract Article PDF–1.5M

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