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Select item 93026831.

Understanding the impact of ZBTB18 missense variation on transcription factor function in neurodevelopment and disease

Julian I.‐T. Heng, Leon Viti, Kye Pugh, Owen J. Marshall, Mark Agostino

J Neurochem. 2022 May; 161(3): 219–235. Published online 2022 Feb 18. doi: 10.1111/jnc.15572

PMCID:: PMC9302683

Abstract Article PDF–1.7M

Select item 80634392.

Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis

Sarah Bazzocco, Higinio Dopeso, Águeda Martínez-Barriocanal, Estefanía Anguita, Rocío Nieto, Jing Li, Elia García-Vidal, Valentina Maggio, Paulo Rodrigues, Priscila Guimarães de Marcondes, Simo Schwartz, Jr, Lauri A. Aaltonen, Alex Sánchez, John M. Mariadason, Diego Arango

Clin Epigenetics. 2021; 13: 88. Published online 2021 Apr 23. doi: 10.1186/s13148-021-01070-0

PMCID:: PMC8063439

Abstract Article PDF–1.3M

Select item 79805333.

The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation

Bin Xie, Tariq E. Khoyratty, Enas Abu-Shah, Pablo F. Cespedes, Andrew J. MacLean, Gabriela Pirgova, Zhiyuan Hu, Ahmed A. Ahmed, Michael L. Dustin, Irina A. Udalova, Tal I. Arnon

J Immunol. 2021 Apr 1; 206(7): 1515–1527. Published online 2021 Feb 19. doi: 10.4049/jimmunol.2000367

PMCID:: PMC7980533

Abstract Article PDF–1.6M

Select item 59676214.

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression

Vita Fedele, Fangping Dai, Anie Priscilla Masilamani, Dieter Henrik Heiland, Eva Kling, Ana Maria Gätjens-Sanchez, Roberto Ferrarese, Leonardo Platania, Doostkam Soroush, Hyunsoo Kim, Sven Nelander, Astrid Weyerbrock, Marco Prinz, Andrea Califano, Antonio Iavarone, Markus Bredel, Maria Stella Carro

Mol Cancer Res. Author manuscript; available in PMC 2018 May 24.

Published in final edited form as: Mol Cancer Res. 2017 Aug; 15(8): 998–1011. Published online 2017 May 16. doi: 10.1158/1541-7786.MCR-16-0494

PMCID:: PMC5967621

Abstract Article PDF–1.8M

Select item 40232235.

A de novo non-sense mutation in ZBTB18 in a patient with features of the 1q43q44 microdeletion syndrome

Sonja A de Munnik, Sixto García-Miñaúr, Alexander Hoischen, Bregje W van Bon, Kym M Boycott, Jeroen Schoots, Lies H Hoefsloot, Nine VAM Knoers, Ernie MHF Bongers, Han G Brunner

Eur J Hum Genet. 2014 Jun; 22(6): 844–846. Published online 2013 Nov 6. doi: 10.1038/ejhg.2013.249

PMCID:: PMC4023223

Abstract Article PDF–303K

Select item 53608446.

Genetic and phenotypic dissection of 1q43q44 microdeletion syndrome and neurodevelopmental phenotypes associated with mutations in ZBTB18 and HNRNPU

Christel Depienne, Caroline Nava, Boris Keren, Solveig Heide, Agnès Rastetter, Sandrine Passemard, Sandra Chantot-Bastaraud, Marie-Laure Moutard, Pankaj B. Agrawal, Grace VanNoy, Joan M. Stoler, David J. Amor, Thierry Billette de Villemeur, Diane Doummar, Caroline Alby, Valérie Cormier-Daire, Catherine Garel, Pauline Marzin, Sophie Scheidecker, Anne de Saint-Martin, Edouard Hirsch, Christian Korff, Armand Bottani, Laurence Faivre, Alain Verloes, Christine Orzechowski, Lydie Burglen, Bruno Leheup, Joelle Roume, Joris Andrieux, Frenny Sheth, Chaitanya Datar, Michael J. Parker, Laurent Pasquier, Sylvie Odent, Sophie Naudion, Marie-Ange Delrue, Cédric Le Caignec, Marie Vincent, Bertrand Isidor, Florence Renaldo, Fiona Stewart, Annick Toutain, Udo Koehler, Birgit Häckl, Celina von Stülpnagel, Gerhard Kluger, Rikke S. Møller, Deb Pal, Tord Jonson, Maria Soller, Nienke E. Verbeek, Mieke M. van Haelst, Carolien de Kovel, Bobby Koeleman, Glen Monroe, Gijs van Haaften, DDD Study, Tania Attié-Bitach, Lucile Boutaud, Delphine Héron, Cyril Mignot

Hum Genet. 2017; 136(4): 463–479. Published online 2017 Mar 10. doi: 10.1007/s00439-017-1772-0

PMCID:: PMC5360844

Abstract Article PDF–2.3M

Select item 227957.

Crystal structure of the BTB domain from PLZF

K. Farid Ahmad, Christian K. Engel, Gilbert G. Privé

Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21): 12123–12128. doi: 10.1073/pnas.95.21.12123

PMCID:: PMC22795

Abstract Article PDF–1.5M

Select item 92537098.

Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism

Anie P. Masilamani, Rana Schulzki, Shuai Yuan, Ira V. Haase, Eva Kling, Franziska Dewes, Geoffroy Andrieux, Melanie Börries, Oliver Schnell, Dieter H. Heiland, Oliver Schilling, Roberto Ferrarese, Maria S. Carro

iScience. 2022 Jul 15; 25(7): 104625. Published online 2022 Jun 17. doi: 10.1016/j.isci.2022.104625

PMCID:: PMC9253709

Abstract Article PDF–5.3M

Select item 1252509.

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

François Fuks, Wendy A. Burgers, Nadia Godin, Masataka Kasai, Tony Kouzarides

EMBO J. 2001 May 15; 20(10): 2536–2544. doi: 10.1093/emboj/20.10.2536

PMCID:: PMC125250

Abstract Article PDF–279K

Select item 54580410.

Myc represses transcription through recruitment of DNA methyltransferase corepressor

Carmen Brenner, Rachel Deplus, Céline Didelot, Axelle Loriot, Emmanuelle Viré, Charles De Smet, Arantxa Gutierrez, Davide Danovi, David Bernard, Thierry Boon, Pier Giuseppe Pelicci, Bruno Amati, Tony Kouzarides, Yvan de Launoit, Luciano Di Croce, François Fuks

EMBO J. 2005 Jan 26; 24(2): 336–346. Published online 2004 Dec 16. doi: 10.1038/sj.emboj.7600509

PMCID:: PMC545804

Abstract Article PDF–241K

Select item 330798511.

RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion

C Xiang, V Baubet, S Pal, L Holderbaum, V Tatard, P Jiang, R V Davuluri, N Dahmane

Cell Death Differ. 2012 Apr; 19(4): 692–702. Published online 2011 Nov 18. doi: 10.1038/cdd.2011.144

PMCID:: PMC3307985

Abstract Article PDF–805K

Select item 968403012.

ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma

Roberto Ferrarese, Annalisa Izzo, Geoffroy Andrieux, Simon Lagies, Johanna Paulina Bartmuss, Anie Priscilla Masilamani, Alix Wasilenko, Daniela Osti, Stefania Faletti, Rana Schulzki, Shuai Yuan, Eva Kling, Valentino Ribecco, Dieter Henrik Heiland, Stefan Tholen, Marco Prinz, Giuliana Pelicci, Bernd Kammerer, Melanie Boerries, Maria Stella Carro

Life Sci Alliance. 2023 Jan; 6(1): e202201400. Published online 2022 Nov 22. doi: 10.26508/lsa.202201400

PMCID:: PMC9684030

Abstract Article PDF–3.3M

Select item 398146813.

Parallel SCF Adaptor Capture Proteomics Reveals a Role for SCF^FBXL17 in NRF2 Activation via BACH1 Repressor Turnover

Meng-Kwang Marcus Tan, Hui-Jun Lim, Eric J. Bennett, Yang Shi, J. Wade Harper

Mol Cell. Author manuscript; available in PMC 2014 Oct 10.

Published in final edited form as: Mol Cell. 2013 Oct 10; 52(1): 9–24. Published online 2013 Sep 12. doi: 10.1016/j.molcel.2013.08.018

PMCID:: PMC3981468

Abstract Article PDF–5.8M

Select item 449199614.

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

Elena Enzo, Giulia Santinon, Arianna Pocaterra, Mariaceleste Aragona, Silvia Bresolin, Mattia Forcato, Daniela Grifoni, Annalisa Pession, Francesca Zanconato, Giulia Guzzo, Silvio Bicciato, Sirio Dupont

EMBO J. 2015 May 12; 34(10): 1349–1370. Published online 2015 Mar 21. doi: 10.15252/embj.201490379

PMCID:: PMC4491996

Abstract Article PDF–1.4M

Select item 399653715.

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism

Roser Corominas, Xinping Yang, Guan Ning Lin, Shuli Kang, Yun Shen, Lila Ghamsari, Martin Broly, Maria Rodriguez, Stanley Tam, Shelly A. Wanamaker, Changyu Fan, Song Yi, Murat Tasan, Irma Lemmens, Xingyan Kuang, Nan Zhao, Dheeraj Malhotra, Jacob J. Michaelson, Vladimir Vacic, Michael A. Calderwood, Frederick P. Roth, Jan Tavernier, Steve Horvath, Kourosh Salehi-Ashtiani, Dmitry Korkin, Jonathan Sebat, David E. Hill, Tong Hao, Marc Vidal, Lilia M. Iakoucheva

Nat Commun. 2014; 5: 3650. Published online 2014 Apr 11. doi: 10.1038/ncomms4650

Correction in:: Nat Commun. 2023; 14: 569.

PMCID:: PMC3996537

Abstract Article PDF–1.9M

Select item 296748916.

A Human MAP Kinase Interactome

Sourav Bandyopadhyay, Chih-yuan Chiang, Jyoti Srivastava, Merril Gersten, Suhaila White, Russell Bell, Cornelia Kurschner, Christopher H. Martin, Mike Smoot, Sudhir Sahasrabudhe, Diane L. Barber, Sumit K. Chanda, Trey Ideker

Nat Methods. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Nat Methods. 2010 Oct; 7(10): 801–805. doi: 10.1038/nmeth.1506

PMCID:: PMC2967489

Abstract Article PDF–1.2M

Select item 800904817.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 509804118.

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions

Charles A. S. Banks, Gina Boanca, Zachary T. Lee, Cassandra G. Eubanks, Gaye L. Hattem, Allison Peak, Lauren E. Weems, Juliana J. Conkright, Laurence Florens, Michael P. Washburn

Mol Cell Proteomics. 2016 Nov; 15(11): 3435–3449. Published online 2016 Sep 8. doi: 10.1074/mcp.M116.060509

PMCID:: PMC5098041

Abstract Article PDF–2.1M

Select item 311015119.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

Select item 268304720.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

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