PMC Links for Gene (Select 10265) - PMC

Select item 73840501.

Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway

Liying Zhu, Longguang Dai, Nenghong Yang, Mi Liu, Shuang Ma, Chengcheng Li, Jie Shen, Tao Lin, Dan Wang, Wei Pan, Xing Li

Cell Biochem Funct. 2020 Jul; 38(5): 621–629. Published online 2020 Mar 9. doi: 10.1002/cbf.3517

PMCID:: PMC7384050

Article PDF–3.3M

Select item 46712172.

Complete re-sequencing of a 2Mb topological domain encompassing the FTO/IRXB genes identifies a novel obesity-associated region upstream of IRX5

Lilian E. Hunt, Boris Noyvert, Leena Bhaw-Rosun, Abdul K. Sesay, Lavinia Paternoster, Ellen A. Nohr, George Davey Smith, Niels Tommerup, Thorkild I. A. Sørensen, Greg Elgar

Genome Med. 2015; 7: 126. Published online 2015 Dec 7. doi: 10.1186/s13073-015-0250-3

PMCID:: PMC4671217

Article PDF–1.3M

Select item 89522103.

The Hematopoietic TALE-Code Shows Normal Activity of IRX1 in Myeloid Progenitors and Reveals Ectopic Expression of IRX3 and IRX5 in Acute Myeloid Leukemia

Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod

Int J Mol Sci. 2022 Mar; 23(6): 3192. Published online 2022 Mar 16. doi: 10.3390/ijms23063192

PMCID:: PMC8952210

Article PDF–6.5M

Select item 83860034.

Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

Débora R. Sobreira, Amelia C. Joslin, Qi Zhang, Iain Williamson, Grace T. Hansen, Kathryn M. Farris, Noboru J. Sakabe, Nasa Sinnott-Armstrong, Grazyna Bozek, Sharon O. Jensen-Cody, Kyle H. Flippo, Carole Ober, Wendy A. Bickmore, Matthew Potthoff, Mengjie Chen, Melina Claussnitzer, Ivy Aneas, Marcelo A. Nóbrega

Science. Author manuscript; available in PMC 2022 Jun 4.

Published in final edited form as: Science. 2021 Jun 4; 372(6546): 1085–1091. doi: 10.1126/science.abf1008

PMCID:: PMC8386003

Article PDF–1.3M

Select item 65881705.

The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis

Linda Holmquist Mengelbier, Simon Lindell‐Munther, Hiroaki Yasui, Caroline Jansson, Javanshir Esfandyari, Jenny Karlsson, Kimberly Lau, Chi‐chung Hui, Daniel Bexell, Sevan Hopyan, David Gisselsson

J Pathol. 2019 Jan; 247(1): 86–98. Published online 2018 Nov 29. doi: 10.1002/path.5171

PMCID:: PMC6588170

Article PDF–5.4M

Select item 49599116.

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

Melina Claussnitzer, Simon N. Dankel, Kyoung-Han Kim, Gerald Quon, Wouter Meuleman, Christine Haugen, Viktoria Glunk, Isabel S. Sousa, Jacqueline L. Beaudry, Vijitha Puviindran, Nezar A. Abdennur, Jannel Liu, Per-Arne Svensson, Yi-Hsiang Hsu, Daniel J. Drucker, Gunnar Mellgren, Chi-Chung Hui, Hans Hauner, Manolis Kellis

N Engl J Med. Author manuscript; available in PMC 2016 Jul 25.

Published in final edited form as: N Engl J Med. 2015 Sep 3; 373(10): 895–907. Published online 2015 Aug 19. doi: 10.1056/NEJMoa1502214

PMCID:: PMC4959911

Article PDF–1.9M

Select item 82127667.

A duplication on chromosome 16q12 affecting the IRXB gene cluster is associated with autosomal dominant cone dystrophy with early tritanopic color vision defect

Susanne Kohl, Pablo Llavona, Alexandra Sauer, Peggy Reuter, Nicole Weisschuh, Melanie Kempf, Florian Alexander Dehmelt, Aristides B Arrenberg, Ieva Sliesoraityte, Eberhart Zrenner, Mary J van Schooneveld, Günther Rudolph, Laura Kühlewein, Bernd Wissinger

Hum Mol Genet. 2021 Jul 1; 30(13): 1218–1229. Published online 2021 Apr 22. doi: 10.1093/hmg/ddab117

PMCID:: PMC8212766

Article PDF–1.0M

Select item 18527898.

A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses

Shin-ichiro Kanno, Hiroyuki Kuzuoka, Shigeru Sasao, Zehui Hong, Li Lan, Satoshi Nakajima, Akira Yasui

EMBO J. 2007 Apr 18; 26(8): 2094–2103. Published online 2007 Mar 29. doi: 10.1038/sj.emboj.7601663

PMCID:: PMC1852789

Article PDF–389K

Select item 39407289.

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence

Beate St Pourcain, David H Skuse, William P Mandy, Kai Wang, Hakon Hakonarson, Nicholas J Timpson, David M Evans, John P Kemp, Susan M Ring, Wendy L McArdle, Jean Golding, George Davey Smith

Mol Autism. 2014; 5: 18. Published online 2014 Feb 24. doi: 10.1186/2040-2392-5-18

PMCID:: PMC3940728

Article PDF–962K

Select item 320295910.

Genome-Wide Association Scan for Survival on Dialysis in African-Americans with Type 2 Diabetes

Mariana Murea, Lingyi Lu, Lijun Ma, Pamela J. Hicks, Jasmin Divers, Caitrin W. McDonough, Carl D. Langefeld, Donald W. Bowden, Barry I. Freedman

Am J Nephrol. 2011 Jun; 33(6): 502–509. Published online 2011 May 5. doi: 10.1159/000327985

PMCID:: PMC3202959

Article PDF–425K

Select item 863966811.

TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease

Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko

Neuron. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031

PMCID:: PMC8639668

Article PDF–2.6M

Select item 800904812.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Article PDF–2.6M

Select item 607772213.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Article PDF–2.4M

Select item 732206714.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Article PDF–2.7M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Article PDF–2.2M

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Article PDF–118K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Article PDF–1.0M

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