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Items: 1 to 20 of 79

1.
ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancer
Samantha Hodder, Millie Fox, Ana Masara Binti Ahmad Mokhtar, Helen R. Mott, Darerca Owen
Small GTPases. 2023; 14(1): 14–25. Published online 2023 May 16. doi: 10.1080/21541248.2023.2212573
PMCID:
PMC10193877
AbstractArticlePDF–2.6M
2.
Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1
Yagmur Kan, YiTing Paung, Markus A. Seeliger, W. Todd Miller
Cells. 2023 Mar; 12(6): 900. Published online 2023 Mar 15. doi: 10.3390/cells12060900
PMCID:
PMC10047419
AbstractArticlePDF–8.4M
3.
TNK2 promoted esophageal cancer progression via activating egfr‐akt signaling
Anqing Zhang, Rongxin Zhang, Zhiming Yang, Rui Tian
J Clin Lab Anal. 2021 Mar; 35(3): e23700. Published online 2021 Jan 23. doi: 10.1002/jcla.23700
PMCID:
PMC7958005
AbstractArticlePDF–404K
4.
Identification of downstream signaling cascades of ACK1 and prognostic classifiers in non-small cell lung cancer
Jinhong Zhu, Yang Liu, Meng Zhao, Kui Cao, Jianqun Ma, Shiyun Peng
Aging (Albany NY) 2021 Feb 15; 13(3): 4482–4502. Published online 2021 Jan 20. doi: 10.18632/aging.202408
PMCID:
PMC7906148
AbstractArticlePDF–4.9M
5.
Research Progress of the Functional Role of ACK1 in Breast Cancer
Xia Liu, Xuan Wang, Lifang Li, Baolin Han
Biomed Res Int. 2019; 2019: 1018034. Published online 2019 Oct 20. doi: 10.1155/2019/1018034
PMCID:
PMC6854235
AbstractArticlePDF–1.0M
6.
Blockade of ACK1/TNK2 To Squelch the Survival of Prostate Cancer Stem-like Cells
Nupam P. Mahajan, Domenico Coppola, Jongphil Kim, Harshani R. Lawrence, Nicholas J. Lawrence, Kiran Mahajan
Sci Rep. 2018; 8: 1954. Published online 2018 Jan 31. doi: 10.1038/s41598-018-20172-z
PMCID:
PMC5792546
AbstractArticlePDF–1.7M
7.
Amplification of ACK1 promotes gastric tumorigenesis via ECD-dependent p53 ubiquitination degradation
Song-Hui Xu, Jin-Zhou Huang, Min Chen, Ming Zeng, Fei-Yan Zou, De Chen, Guang-Rong Yan
Oncotarget. 2017 Feb 21; 8(8): 12705–12716. Published online 2015 Oct 20. doi: 10.18632/oncotarget.6194
PMCID:
PMC5355047
AbstractArticlePDF–5.6M
8.
Involvement of Activated Cdc42 Kinase1 in Colitis and Colorectal Neoplasms
Chaolan Lv, Hongxiang Gu, Xinmei Zhao, Liyun Huang, Sanxi Zhou, Fachao Zhi
Med Sci Monit. 2016; 22: 4794–4802. Published online 2016 Dec 7. doi: 10.12659/MSM.902274
PMCID:
PMC5158129
AbstractArticlePDF–673K
9.
Ack1 overexpression promotes metastasis and indicates poor prognosis of hepatocellular carcinoma
Xiong Lei, Yun-feng Li, Guo-dong Chen, Di-peng Ou, Xiao-xin Qiu, Chao-hui Zuo, Lian-Yue Yang
Oncotarget. 2015 Dec 1; 6(38): 40622–40641. Published online 2015 Oct 20. doi: 10.18632/oncotarget.5872
PMCID:
PMC4747357
AbstractArticlePDF–12M
10.
Identification and characterization of Tyrosine Kinase Non-receptor 2 mutations in leukemia through integration of kinase inhibitor screening and genomic analysis
Julia E. Maxson, Melissa L. Abel, Jinhua Wang, Xianming Deng, Sina Reckel, Samuel B. Luty, Huahang Sun, Julie Gorenstein, Seamus Hughes, Daniel Bottomly, Beth Wilmot, Shannon K. McWeeney, Jerald Radich, Oliver Hantschel, Richard E Middleton, Nathanael S. Gray, Brian J. Druker, Jeffrey W. Tyner
Cancer Res. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Cancer Res. 2016 Jan 1; 76(1): 127–138. Published online 2015 Dec 17. doi: 10.1158/0008-5472.CAN-15-0817
PMCID:
PMC4703549
AbstractArticlePDF–1.3M
11.
Cancer-associated Mutations Activate the Nonreceptor Tyrosine Kinase Ack1
Victoria Prieto-Echagüe, Azad Gucwa, Barbara P. Craddock, Deborah A. Brown, W. Todd Miller
J Biol Chem. 2010 Apr 2; 285(14): 10605–10615. Published online 2010 Jan 28. doi: 10.1074/jbc.M109.060459
PMCID:
PMC2856269
AbstractArticlePDF–1.7M
12.
Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1
Edward Htun van der Horst, Yan Y. Degenhardt, Astrid Strelow, Anthony Slavin, Lawrence Chinn, Jessica Orf, Minqing Rong, Shyun Li, Lei-Hoon See, Ken Q. C. Nguyen, Timothy Hoey, Holger Wesche, Scott Powers
Proc Natl Acad Sci U S A. 2005 Nov 1; 102(44): 15901–15906. Published online 2005 Oct 24. doi: 10.1073/pnas.0508014102
PMCID:
PMC1276100
AbstractArticlePDF–524K
13.
ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway
Di Zheng, Zhun Wei, Chong Zhang, Wenda Liu, Changtian Gong, Fei Wu, Weichun Guo
Biol Direct. 2024; 19: 28. Published online 2024 Apr 22. doi: 10.1186/s13062-024-00472-3
PMCID:
PMC11034355
AbstractArticlePDF–15M
14.
Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk
Yagmur Kan, YiTing Paung, Yunyoung Kim, Markus A. Seeliger, W. Todd Miller
Biochemistry. Author manuscript; available in PMC 2023 Mar 29.
Published in final edited form as: Biochemistry. 2023 Mar 21; 62(6): 1124–1137. Published online 2023 Feb 28. doi: 10.1021/acs.biochem.2c00685
PMCID:
PMC10052838
AbstractArticlePDF–1.1M
15.
Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells
Boon Tin Chua, Shu Jing Lim, Su Chin Tham, Wei Jie Poh, Axel Ullrich
Mol Oncol. 2010 Aug; 4(4): 323–334. Published online 2010 Mar 19. doi: 10.1016/j.molonc.2010.03.001
PMCID:
PMC5527913
AbstractArticlePDF–1.0M
16.
Whole-Exome Sequencing in Familial Parkinson Disease
Janice L. Farlow, Laurie A. Robak, Kurt Hetrick, Kevin Bowling, Eric Boerwinkle, Zeynep H. Coban-Akdemir, Tomasz Gambin, Richard A. Gibbs, Shen Gu, Preti Jain, Joseph Jankovic, Shalini Jhangiani, Kaveeta Kaw, Dongbing Lai, Hai Lin, Hua Ling, Yunlong Liu, James R. Lupski, Donna Muzny, Paula Porter, Elizabeth Pugh, Janson White, Kimberly Doheny, Richard M. Myers, Joshua M. Shulman, Tatiana Foroud
JAMA Neurol. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: JAMA Neurol. 2016 Jan; 73(1): 68–75. doi: 10.1001/jamaneurol.2015.3266
PMCID:
PMC4946647
AbstractArticlePDF–720K
17.
Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1
Meghan L Rudd, Hassan Mohamed, Jessica C Price, Andrea J O’Hara, Matthieu Le Gallo, Mary Ellen Urick, NISC Comparative Sequencing Program, Pedro Cruz, Suiyuan Zhang, Nancy F Hansen, Andrew K Godwin, Dennis C Sgroi, Tyra G Wolfsberg, James C Mullikin, Maria J Merino, Daphne W Bell
BMC Cancer. 2014; 14: 884. Published online 2014 Nov 26. doi: 10.1186/1471-2407-14-884
PMCID:
PMC4258955
AbstractArticlePDF–502K
18.
Bosutinib inhibits migration and invasion via ack1 in kras mutant non-small cell lung cancer
Daniel SW Tan, Benjamin Haaland, Jia Min Gan, Su Chin Tham, Indrajit Sinha, Eng Huat Tan, Kiat Hon Lim, Angela Takano, Sai Sakktee Krisna, Minn Minn Myint Thu, Hoe Peng Liew, Axel Ullrich, Wan-Teck Lim, Boon Tin Chua
Mol Cancer. 2014; 13: 13. Published online 2014 Jan 24. doi: 10.1186/1476-4598-13-13
PMCID:
PMC3930897
AbstractArticlePDF–2.9M
19.
Ack1-mediated Androgen Receptor Phosphorylation Modulates Radiation Resistance in Castration-resistant Prostate Cancer
Kiran Mahajan, Domenico Coppola, Bhupendra Rawal, Y. Ann Chen, Harshani R. Lawrence, Robert W. Engelman, Nicholas J. Lawrence, Nupam P. Mahajan
J Biol Chem. 2012 Jun 22; 287(26): 22112–22122. Published online 2012 May 7. doi: 10.1074/jbc.M112.357384
PMCID:
PMC3381169
AbstractArticlePDF–2.6M
20.
Ack1 Tyrosine Kinase Activation Correlates with Pancreatic Cancer Progression
Kiran Mahajan, Domenico Coppola, Y. Ann Chen, Weiwei Zhu, Harshani R. Lawrence, Nicholas J. Lawrence, Nupam P. Mahajan
Am J Pathol. 2012 Apr; 180(4): 1386–1393. doi: 10.1016/j.ajpath.2011.12.028
PMCID:
PMC3349895
AbstractArticlePDF–1.3M

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