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Select item 73971171.

Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance

Hongwei Gao, Peirong Bai, Lin Xiao, Mengjia Shen, Qiuxiao Yu, Yuanyuan Lei, Wenting Huang, Xiang Lin, Xinyi Zheng, Tao Wei, Yong Jiang, Feng Ye, Hong Bu

J Biol Chem. 2020 Jul 31; 295(31): 10726–10740. Published online 2020 Jun 12. doi: 10.1074/jbc.RA119.012404

PMCID:: PMC7397117

Abstract Article PDF–5.2M

Select item 1339602.

TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4

Sohail Malik, Annika E. Wallberg, Yun Kyoung Kang, Robert G. Roeder

Mol Cell Biol. 2002 Aug; 22(15): 5626–5637. doi: 10.1128/MCB.22.15.5626-5637.2002

PMCID:: PMC133960

Abstract Article PDF–330K

Select item 386703.

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

J D Fondell, H Ge, R G Roeder

Proc Natl Acad Sci U S A. 1996 Aug 6; 93(16): 8329–8333. doi: 10.1073/pnas.93.16.8329

PMCID:: PMC38670

Summary Page Browse PDF–1.5M

Select item 29202864.

CDK8 is a positive regulator of transcriptional elongation within the serum response network

Aaron J. Donner, Christopher C. Ebmeier, Dylan J. Taatjes, Joaquín M. Espinosa

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Aug 11.

Published in final edited form as: Nat Struct Mol Biol. 2010 Feb; 17(2): 194–201. Published online 2010 Jan 24. doi: 10.1038/nsmb.1752

PMCID:: PMC2920286

Abstract Article PDF–2.1M

Select item 2918145.

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

Gerhard Mittler, Thomas Stühler, Lisa Santolin, Thomas Uhlmann, Elisabeth Kremmer, F. Lottspeich, Lucia Berti, Michael Meisterernst

EMBO J. 2003 Dec 15; 22(24): 6494–6504. doi: 10.1093/emboj/cdg619

PMCID:: PMC291814

Abstract Article PDF–382K

Select item 23963956.

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3

Krista D Meyer, Aaron J Donner, Matthew T Knuesel, Autumn G York, Joaquín M Espinosa, Dylan J Taatjes

EMBO J. 2008 May 21; 27(10): 1447–1457. Published online 2008 Apr 17. doi: 10.1038/emboj.2008.78

PMCID:: PMC2396395

Abstract Article PDF–303K

Select item 22232837.

STAGA Recruits Mediator to the MYC Oncoprotein To Stimulate Transcription and Cell Proliferation

Xiaohui Liu, Marina Vorontchikhina, Yuan-Liang Wang, Francesco Faiola, Ernest Martinez

Mol Cell Biol. 2008 Jan; 28(1): 108–121. Published online 2007 Oct 27. doi: 10.1128/MCB.01402-07

PMCID:: PMC2223283

Abstract Article PDF–664K

Select item 35663078.

The SCF–Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator

Michael A. Davis, Elizabeth A. Larimore, Brian M. Fissel, Jherek Swanger, Dylan J. Taatjes, Bruce E. Clurman

Genes Dev. 2013 Jan 15; 27(2): 151–156. doi: 10.1101/gad.207720.112

PMCID:: PMC3566307

Abstract Article PDF–1.2M

Select item 1224019.

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function invitro

Yun Kyoung Kang, Mohamed Guermah, Chao-Xing Yuan, Robert G. Roeder

Proc Natl Acad Sci U S A. 2002 Mar 5; 99(5): 2642–2647. Published online 2002 Feb 26. doi: 10.1073/pnas.261715899

PMCID:: PMC122401

Abstract Article PDF–285K

Select item 274736610.

Centromere specific assembly of CENP-A nucleosomes is mediated by HJURP

Daniel R. Foltz, Lars E.T. Jansen, Aaron O. Bailey, John R. Yates, III, Emily A. Bassett, Stacey Wood, Ben E. Black, Don W. Cleveland

Cell. Author manuscript; available in PMC 2010 May 1.

Published in final edited form as: Cell. 2009 May 1; 137(3): 472–484. doi: 10.1016/j.cell.2009.02.039

PMCID:: PMC2747366

Abstract Article PDF–2.3M

Select item 510493711.

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin

Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers

J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582

PMCID:: PMC5104937

Abstract Article PDF–4.4M

Select item 108404112.

Novel critical role of a human Mediator complex for basal RNA polymerase II transcription

Gerhard Mittler, Elisabeth Kremmer, H. Th. Marc Timmers, Michael Meisterernst

EMBO Rep. 2001 Sep 15; 2(9): 808–813. doi: 10.1093/embo-reports/kve186

PMCID:: PMC1084041

Abstract Article PDF–413K

Select item 31108613.

Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes

Yutaka Suzuki, Tatsuhiko Tsunoda, Jun Sese, Hirotoshi Taira, Junko Mizushima-Sugano, Hiroko Hata, Toshio Ota, Takao Isogai, Toshihiro Tanaka, Yusuke Nakamura, Akira Suyama, Yoshiyuki Sakaki, Shinichi Morishita, Kousaku Okubo, Sumio Sugano

Genome Res. 2001 May; 11(5): 677–684. doi: 10.1101/gr.164001

PMCID:: PMC311086

Abstract Article PDF–581K

Select item 410496414.

Subunit architecture and functional modular rearrangements of the transcriptional Mediator complex

Kuang-Lei Tsai, Chieri Tomomori-Sato, Shigeo Sato, Ronald C. Conaway, Joan W. Conaway, Francisco J. Asturias

Cell. Author manuscript; available in PMC 2015 Jun 5.

Published in final edited form as: Cell. 2014 Jun 5; 157(6): 1430–1444. Published online 2014 May 29. doi: 10.1016/j.cell.2014.05.015

Correction in:: volume 158 on page 463

PMCID:: PMC4104964

Abstract Article PDF–939K

Select item 359166515.

Identification of the Hypoxia-inducible Factor 2α Nuclear Interactome in Melanoma Cells Reveals Master Proteins Involved in Melanoma Development

Anne-Lise Steunou, Manuelle Ducoux-Petit, Ikrame Lazar, Bernard Monsarrat, Monique Erard, Catherine Muller, Eric Clottes, Odile Burlet-Schiltz, Laurence Nieto

Mol Cell Proteomics. 2013 Mar; 12(3): 736–748. Published online 2012 Dec 28. doi: 10.1074/mcp.M112.020727

PMCID:: PMC3591665

Abstract Article PDF–3.0M

Select item 282392216.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

Anna Malovannaya, Yehua Li, Yaroslava Bulynko, Sung Yun Jung, Yi Wang, Rainer B. Lanz, Bert W. O’Malley, Jun Qin

Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6): 2431–2436. Published online 2010 Jan 22. doi: 10.1073/pnas.0912599106

Correction in:: Proc Natl Acad Sci U S A. 2010 Mar 30; 107(13): 6118.

PMCID:: PMC2823922

Abstract Article PDF–566K

Select item 314532517.

Human Mediator Subunit Med26 Functions As A Docking Site For Transcription Elongation Factors

Hidehisa Takahashi, Tari J. Parmely, Shigeo Sato, Chieri Tomomori-Sato, Charles A. S. Banks, Stephanie E. Kong, Henrietta Szutorisz, Selene K. Swanson, Skylar Martin-Brown, Michael P. Washburn, Laurence Florens, Chris Seidel, Chengqi Lin, Edwin R. Smith, Ali Shilatifard, Ronald C. Conaway, Joan W. Conaway

Cell. Author manuscript; available in PMC 2012 Jul 8.

Published in final edited form as: Cell. 2011 Jul 8; 146(1): 92–104. doi: 10.1016/j.cell.2011.06.005

PMCID:: PMC3145325

Abstract Article PDF–1.9M

Select item 440166218.

FBXW7 modulates cellular stress response and metastatic potential via HSF1 post-translational modification

Nikos Kourtis, Rana S. Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T. Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt, Emily I. Chen, Julide T. Celebi, Charalampos Lazaris, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Iannis Aifantis

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 322–332. doi: 10.1038/ncb3121

PMCID:: PMC4401662

Abstract Article PDF–5.0M

Select item 455321419.

Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer

Manish Kumar, Ajay Matta, Olena Masui, Gunjan Srivastava, Jatinder Kaur, Alok Thakar, Nootan Kumar Shukla, Ajoy RoyChoudhury, Meherchand Sharma, Paul G. Walfish, K. W. Michael Siu, Shyam Singh Chauhan, Ranju Ralhan

J Transl Med. 2015; 13: 285. Published online 2015 Aug 30. doi: 10.1186/s12967-015-0637-3

PMCID:: PMC4553214

Abstract Article PDF–2.0M

Select item 1008090820.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

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PMC Links for Gene (Select 10025) (55)
PMC
tudor domain-containing protein 5 isoform 3 [Homo sapiens]
tudor domain-containing protein 5 isoform 3 [Homo sapiens]
gi|312283653|ref|NP_001186021.1|

Protein
Homo sapiens ribosomal protein L17, mRNA (cDNA clone MGC:22482 IMAGE:4251433), c...
Homo sapiens ribosomal protein L17, mRNA (cDNA clone MGC:22482 IMAGE:4251433), complete cds
gi|17389602|gb|BC017831.1|

Nucleotide
602543234F1 NIH_MGC_60 Homo sapiens cDNA clone IMAGE:4665561 5', mRNA sequence
602543234F1 NIH_MGC_60 Homo sapiens cDNA clone IMAGE:4665561 5', mRNA sequence
gi|13459431|gnl|dbEST|8206987|gb|BG 4.1|

Nucleotide

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