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Items: 1 to 20 of 204

1.
Induction of Glucose Production by Heterocyclic Amines is Dependent on N-acetyltransferase 2 Genetic Polymorphism in Cryopreserved Human Hepatocytes
Kennedy M. Walls, Kyung U. Hong, David W. Hein
Toxicol Lett. Author manuscript; available in PMC 2024 Jul 7.
Published in final edited form as: Toxicol Lett. 2023 Jul 1; 383: 192–195. Published online 2023 Jul 7. doi: 10.1016/j.toxlet.2023.07.002
PMCID:
PMC10528954
AbstractArticlePDF–409K
2.
N-Acetyltransferase 2 Haplotype Modifies Risks for Both Dyslipidemia and Urinary Bladder Cancer
Kyung U. Hong, David W. Hein
Pharmacogenet Genomics. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Pharmacogenet Genomics. 2023 Aug 1; 33(6): 136–137. Published online 2023 May 29. doi: 10.1097/FPC.0000000000000500
PMCID:
PMC10524719
AbstractArticlePDF–293K
3.
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances
Raúl A. Salazar-González, Mark A. Doll, David W Hein
Arch Toxicol. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Arch Toxicol. 2023 Jan; 97(1): 189–199. Published online 2022 Sep 23. doi: 10.1007/s00204-022-03383-2
PMCID:
PMC10187882
AbstractArticlePDF–956K
4.
NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review
Jorge E. Gutiérrez-Virgen, Maricela Piña-Pozas, Esther A. Hernández-Tobías, Lucia Taja-Chayeb, Ma. de Lourdes López-González, Marco A. Meraz-Ríos, Rocío Gómez
PLoS One. 2023; 18(4): e0283726. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283726
PMCID:
PMC10079069
AbstractArticlePDF–2.5M
5.
Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing
Maano V. Masiphephethu, Margaretha Sariko, Thomas Walongo, Athanasia Maro, Dorcus Mduma, Jean Gratz, Mohammad Alshaer, Charles A. Peloquin, Estomih Mduma, Stellah G. Mpagama, Tania Thomas, Eric R. Houpt, Afsatou Traore, Pascal Bessong, Scott K. Heysell, Darwin J. Operario
Tuberculosis (Edinb) Author manuscript; available in PMC 2023 Jan 29.
Published in final edited form as: Tuberculosis (Edinb). 2022 Sep; 136: 102246. Published online 2022 Aug 8. doi: 10.1016/j.tube.2022.102246
PMCID:
PMC9884397
AbstractArticlePDF–864K
6.
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines
Kyung U Hong, Raúl A Salazar-González, Kennedy M Walls, David W Hein
Toxicol Sci. 2022 Dec; 190(2): 158–172. Published online 2022 Sep 26. doi: 10.1093/toxsci/kfac103
PMCID:
PMC9702998
AbstractArticlePDF–922K
7.
Influence of NAT2 Genotype and Maturation on Isoniazid Exposure in Low-Birth-Weight and Preterm Infants With or Without Human Immunodeficiency Virus (HIV) Exposure
Agathe Béranger, Adrie Bekker, Belén P Solans, Mark F Cotton, Mark Mirochnick, Avy Violari, Jiajia Wang, Mae Cababasay, Lubbe Wiesner, Renee Browning, Jack Moye, Edmund V Capparelli, Radojka M Savic
Clin Infect Dis. 2022 Sep 15; 75(6): 1037–1045. Published online 2022 Feb 4. doi: 10.1093/cid/ciac001
PMCID:
PMC9522418
AbstractArticlePDF–8.5M
8.
Expression of Arylamine N-Acetyltransferase 2 Activity in Immortalized Human Bronchial Epithelial Cells
James T.F. Wise, Raúl A. Salazar-González, Mariam R. Habil, Mark A. Doll, David W. Hein
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2022 May 1; 442: 115993. Published online 2022 Mar 27. doi: 10.1016/j.taap.2022.115993
PMCID:
PMC9112076
AbstractArticlePDF–1.3M
9.
Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia
Entesar M Tebien, Hiba B Khalil, Jeremy Mills, Abozer Y. Elderdery
Asian Pac J Cancer Prev. 2020 Dec; 21(12): 3711–3717. doi: 10.31557/APJCP.2020.21.12.3711
PMCID:
PMC8046315
AbstractArticlePDF–397K
10.
Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2
Dr. Louis P. Conway, Dr. Veronica Rendo, M. Sc. Mário S. P. Correia, Prof. Dr. Ingvar A. Bergdahl, Prof. Dr. Tobias Sjöblom, Prof. Dr. Daniel Globisch
Angew Chem Int Ed Engl. 2020 Aug 17; 59(34): 14342–14346. Published online 2020 Jul 8. doi: 10.1002/anie.202005915
PMCID:
PMC7497018
AbstractArticlePDF–2.0M
11.
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes
Mariam R. Habil, Mark A. Doll, David W. Hein
Pharmacogenet Genomics. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Pharmacogenet Genomics. 2020 Apr; 30(3): 61–65. doi: 10.1097/FPC.0000000000000394
PMCID:
PMC7060095
AbstractArticlePDF–219K
12.
The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis
Jeong Yee, So Min Kim, Ji Min Han, Nari Lee, Ha Young Yoon, Hye Sun Gwak
Sci Rep. 2020; 10: 3658. Published online 2020 Feb 27. doi: 10.1038/s41598-020-60467-8
PMCID:
PMC7046788
AbstractArticlePDF–2.4M
13.
Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay
Kristin J. Baldauf, Raúl A. Salazar-González, Mark A. Doll, William M. Pierce, Jr., J. Christopher States, David W. Hein
Environ Mol Mutagen. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: Environ Mol Mutagen. 2020 Feb; 61(2): 235–245. Published online 2019 Sep 30. doi: 10.1002/em.22331
PMCID:
PMC7017392
AbstractArticlePDF–604K
14.
NAT2 gene polymorphisms and endometriosis risk: A PRISMA-compliant meta-analysis
Zhangming Wei, Mengmeng Zhang, Xinyue Zhang, Mingyu Yi, Xiaomeng Xia, Xiaoling Fang
PLoS One. 2019; 14(12): e0227043. Published online 2019 Dec 27. doi: 10.1371/journal.pone.0227043
PMCID:
PMC6934289
AbstractArticlePDF–1.3M
15.
N‐acetyl transferase 2/environmental factors and their association as a modulating risk factor for sporadic colon and rectal cancer
Lucia M. Procopciuc, Gelu Osian, Mihaela Iancu
J Clin Lab Anal. 2017 Sep; 31(5): e22098. Published online 2016 Nov 24. doi: 10.1002/jcla.22098
PMCID:
PMC6816822
AbstractArticlePDF–328K
16.
Doneness Preferences, Meat and Meat-derived Heterocyclic Amines Intake, and NAT2 Polymorphisms: Association with Colorectal Adenoma in Japanese Brazilians
Sanjeev Budhathoki, Motoki Iwasaki, Taiki Yamaji, Gerson Shigeaki Hamada, Nelson Tomio Miyajima, Jose Carlos Zampieri, Sangita Sharma, Mohammadreza Pakseresht, Fariba Kolahdooz, Junko Ishihara, Ribeka Takachi, Hadrien Charvat, Loïic Le Marchand, Shoichiro Tsugane
Eur J Cancer Prev. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: Eur J Cancer Prev. 2020 Jan; 29(1): 7–14. doi: 10.1097/CEJ.0000000000000506
PMCID:
PMC6761046
AbstractArticlePDF–345K
17.
Association between NAT2 polymorphisms and acute leukemia risk: A meta-analysis
Xiaoxiao Zhu, Yanbing Liu, Guangwu Chen, Qiang Guo, Zhen Zhang, Lin Zhao, Ran Wei, Xunqiang Yin, Yunhong Zhang, Bin Wang, Xia Li
Medicine (Baltimore) 2019 Mar; 98(12): e14942. Published online 2019 Mar 22. doi: 10.1097/MD.0000000000014942
PMCID:
PMC6709067
AbstractArticlePDF–829K
18.
Genomewide Association Study Confirming the Association of NAT2 with Susceptibility to Antituberculosis Drug-Induced Liver Injury in Thai Patients
Supharat Suvichapanich, Sukanya Wattanapokayakit, Taisei Mushiroda, Hideki Yanai, Charoen Chuchottawon, Tassawan Kantima, Supalert Nedsuwan, Wimon Suwankesawong, Cholticha Sonsupap, Roongkarn Pannarunothai, Sukanya Tumpattanakul, Warawut Bamrungram, Achara Chaiwong, Surakameth Mahasirimongkol, Sasithorn Mameechai, Weerapat Panthong, Nantawan Klungtes, Amara Munsoo, Udomrat Chauychana, Molrudee Maneerat, Koya Fukunaga, Yosuke Omae, Katsushi Tokunaga
Antimicrob Agents Chemother. 2019 Aug; 63(8): e02692-18. Prepublished online 2019 May 20. Published online 2019 Jul 25. doi: 10.1128/AAC.02692-18
PMCID:
PMC6658740
AbstractArticlePDF–1.4M
19.
Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis
Anushka Naidoo, Maxwell Chirehwa, Veron Ramsuran, Helen McIlleron, Kogieleum Naidoo, Nonhlanhla Yende-Zuma, Ravesh Singh, Sinaye Ncgapu, John Adamson, Katya Govender, Paolo Denti, Nesri Padayatchi
Pharmacogenomics. 2019 Mar; 20(4): 225–240. Published online 2019 Feb 15. doi: 10.2217/pgs-2018-0166
PMCID:
PMC6562923
AbstractArticlePDF–2.2M
20.
N-ACETYLTRANSFERASE 2 ENZYME GENOTYPE-PHENOTYPE DISCORDANCES IN BOTH HIV-NEGATIVE AND HIV-POSITIVE NIGERIANS
Olayinka A. Kotila, Olufunmilayo I. Fawole, Olufunmilayo I. Olopade, Adejumoke I. Ayede, Adeyinka G. Falusi, Chinedum P. Babalola
Pharmacogenet Genomics. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Pharmacogenet Genomics. 2019 Jul; 29(5): 106–113. doi: 10.1097/FPC.0000000000000373
PMCID:
PMC6542708
AbstractArticlePDF–802K

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