PMC

Amino acid sequence identity and similarity matrices of bioluminescence pathway genes in the species of the Omphalotus lineage. The pairwise amino acid sequence identities and similarities of hispidin synthase (HispS), hispidin-3-hydroxylase (H3H), and luciferase (Luz) of the fungal species in the Omphalotus lineage, including Omphalotus guepiniiformis, were calculated in Sequence Identity and Similarity (http://imed.med.ucm.es/Tools/sias.html) using the sequence alignment obtained by Clustal Omega (https://www.ebi.ac.uk/Tools/msa/clustalo/). The percent identities and similarities were presented on the upper right and the bottom left, respectively. Og, O. guepiniiformis; Oo, O. olearius; Ng, Neonothopanus gardneri; Nn, N. nambi.

Metabolites produced by Lachnum papyraceum and in part also from Gilmaniella humicola (22–34, 35–37, 38–41, 42–45, and 47) and by Omphalotus olearius (48–50).

Unrooted Neighbor-Joining phylogram of sesquiterpene synthase (STS) of Hericium erinaceus were constructed based homologous protein sequences. STS from Coprinopsis cinereus (Cop), Omphalotus olearius (Omp), Fomitopsis pinicola (Fompi1), Stereum hirsutum (Sh) and the single STS described from Armillaria gallica (Armga1) and Boreostereum vibrans (SqtB) are labeled. Detail information of the sequences used in phylogram can be found in Supplement Table .

Phylogenetic clustering of putative basidiomycete sesquiterpene synthases. The protein sequences identified from the T. vaccinum genome are labeled in red; conceptually translated protein sequences of other basidiomycetes are from Antrodia cinnamomea, Armillaria gallica, Boreostereum vibrans, Coprinopsis cinerea, Coniophora puteana, Fomitopsis pinicola, Lignosus rhinoceros, Omphalotus olearius, Stereum hirsutum, and Schizophyllum commune; gene identifiers are given in brackets if no protein names are available.